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The map label for this gene is mnaA [H]

Identifier: 169823826

GI number: 169823826

Start: 149489

End: 150580

Strand: Direct

Name: mnaA [H]

Synonym: FMG_0129

Alternate gene names: 169823826

Gene position: 149489-150580 (Clockwise)

Preceding gene: 169823825

Following gene: 169823832

Centisome position: 8.32

GC content: 36.72

Gene sequence:

>1092_bases
ATGAAAAAAGTAATGGTGGTTTTTGGGACAAGACCAGAAGCTATTAAAATGTGTCCACTTGTAAAAGAACTCAAAAAAAG
AGACGAATTCGAAGTTTGTGTACTTGTAACTGGACAGCACAAAGAAATGTTGCGTCAAGTATTGGACGTTTTCGAAATAA
AAGAAGACTACAACTTGGATATCATGAAAGAAAAACAAAGCTTGTTCGATGTTACCACAACTATTTTAGACAAAATAAAA
TCTATATTAGAAGAAGAAAAACCAGACATTGTCTTGGTTCACGGAGATACTTCGACAAGTTTTGTTGCAGGACTTGCCGC
ATTTTATTTGAGAATACCAGTAGGTCATGTGGAAGCTGGATTGAGAACTTACAACAAATACTCTCCATATCCGGAAGAAT
TCAACAGACAAGCCATAGGATCGTTGGCAGATTTCCACTTCGCACCAACTACAACTGCAAGGGATAATTTGCTTCGAGAA
AACAAAGACGAATCCAAAGTTTTCGTAACGGGAAACACAGTAATAGATGCACTTCAGACAACAGTTGTTGACAATTATCA
AAACGAAAATTTGATTGAAGGCAAGAAAATGATTCTTCTAACAATGCACAGAAGAGAAAACTTGGGAGAATCCATGAAGA
ATTCCTTCAGAGCAATCAAACGAGTTGTCAACGAAAACGAAGATATATATGTGATTTATCCGATACATTTGAATCCAAAA
GTACGAGAAATCGCAAACGAAGTATTTGACAATCATCCTAGAATCAAACTAATTGAGCCGTTGAATGTAGTTGATTTTCA
CAATTTCATGAAACAATCATTCTTCGTAATGACAGATTCAGGCGGAATTCAAGAAGAAGCTCCAGCGCTTGGAAAACCTG
TTTTGGTAATGAGAGACACAACAGAAAGACCAGAAGGAGTAGAGGCAGGGACATTAAAATTAACTGGGCTTTGCGAAGAA
GACATCTACAACGAAATGACCAAACTTCTTACCGATAAAAATGAATACGACAAAATGAGTGAAGCCACAAACCCTTACGG
AGATGGCCACGCATCAGAAAGAATCTGTGACATTTTATCAAAAAATCTATAA

Upstream 100 bases:

>100_bases
AAGAAACATCGATGCTGAAAACAAATACAATTTCTACAAATTATAAAATAAATTAAAGGGCGCTAAATTTGCAGCGCCTT
TTTTTAAAAAGAGGTAAAAA

Downstream 100 bases:

>100_bases
ACAAAAAAAATCCAACTTCATATAGAAGTTGGATTTTGTATTTAAACGTCAAATAAATTTGACGCGTTAACAGATTGGAT
TTTCTCAATATCTTAATCTG

Product: UDP-N-acetyl-glucosamine-2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKKVMVVFGTRPEAIKMCPLVKELKKRDEFEVCVLVTGQHKEMLRQVLDVFEIKEDYNLDIMKEKQSLFDVTTTILDKIK
SILEEEKPDIVLVHGDTSTSFVAGLAAFYLRIPVGHVEAGLRTYNKYSPYPEEFNRQAIGSLADFHFAPTTTARDNLLRE
NKDESKVFVTGNTVIDALQTTVVDNYQNENLIEGKKMILLTMHRRENLGESMKNSFRAIKRVVNENEDIYVIYPIHLNPK
VREIANEVFDNHPRIKLIEPLNVVDFHNFMKQSFFVMTDSGGIQEEAPALGKPVLVMRDTTERPEGVEAGTLKLTGLCEE
DIYNEMTKLLTDKNEYDKMSEATNPYGDGHASERICDILSKNL

Sequences:

>Translated_363_residues
MKKVMVVFGTRPEAIKMCPLVKELKKRDEFEVCVLVTGQHKEMLRQVLDVFEIKEDYNLDIMKEKQSLFDVTTTILDKIK
SILEEEKPDIVLVHGDTSTSFVAGLAAFYLRIPVGHVEAGLRTYNKYSPYPEEFNRQAIGSLADFHFAPTTTARDNLLRE
NKDESKVFVTGNTVIDALQTTVVDNYQNENLIEGKKMILLTMHRRENLGESMKNSFRAIKRVVNENEDIYVIYPIHLNPK
VREIANEVFDNHPRIKLIEPLNVVDFHNFMKQSFFVMTDSGGIQEEAPALGKPVLVMRDTTERPEGVEAGTLKLTGLCEE
DIYNEMTKLLTDKNEYDKMSEATNPYGDGHASERICDILSKNL
>Mature_363_residues
MKKVMVVFGTRPEAIKMCPLVKELKKRDEFEVCVLVTGQHKEMLRQVLDVFEIKEDYNLDIMKEKQSLFDVTTTILDKIK
SILEEEKPDIVLVHGDTSTSFVAGLAAFYLRIPVGHVEAGLRTYNKYSPYPEEFNRQAIGSLADFHFAPTTTARDNLLRE
NKDESKVFVTGNTVIDALQTTVVDNYQNENLIEGKKMILLTMHRRENLGESMKNSFRAIKRVVNENEDIYVIYPIHLNPK
VREIANEVFDNHPRIKLIEPLNVVDFHNFMKQSFFVMTDSGGIQEEAPALGKPVLVMRDTTERPEGVEAGTLKLTGLCEE
DIYNEMTKLLTDKNEYDKMSEATNPYGDGHASERICDILSKNL

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=377, Percent_Identity=22.0159151193634, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI4885285, Length=377, Percent_Identity=22.0159151193634, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI298566312, Length=377, Percent_Identity=22.0159151193634, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI48994967, Length=371, Percent_Identity=53.3692722371968, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41471; Mature: 41471

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVMVVFGTRPEAIKMCPLVKELKKRDEFEVCVLVTGQHKEMLRQVLDVFEIKEDYNLD
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCC
IMKEKQSLFDVTTTILDKIKSILEEEKPDIVLVHGDTSTSFVAGLAAFYLRIPVGHVEAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHH
LRTYNKYSPYPEEFNRQAIGSLADFHFAPTTTARDNLLRENKDESKVFVTGNTVIDALQT
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEECHHHHHHHHH
TVVDNYQNENLIEGKKMILLTMHRRENLGESMKNSFRAIKRVVNENEDIYVIYPIHLNPK
HHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCH
VREIANEVFDNHPRIKLIEPLNVVDFHNFMKQSFFVMTDSGGIQEEAPALGKPVLVMRDT
HHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCEEEEECC
TERPEGVEAGTLKLTGLCEEDIYNEMTKLLTDKNEYDKMSEATNPYGDGHASERICDILS
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHH
KNL
CCC
>Mature Secondary Structure
MKKVMVVFGTRPEAIKMCPLVKELKKRDEFEVCVLVTGQHKEMLRQVLDVFEIKEDYNLD
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCC
IMKEKQSLFDVTTTILDKIKSILEEEKPDIVLVHGDTSTSFVAGLAAFYLRIPVGHVEAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHH
LRTYNKYSPYPEEFNRQAIGSLADFHFAPTTTARDNLLRENKDESKVFVTGNTVIDALQT
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEECHHHHHHHHH
TVVDNYQNENLIEGKKMILLTMHRRENLGESMKNSFRAIKRVVNENEDIYVIYPIHLNPK
HHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCH
VREIANEVFDNHPRIKLIEPLNVVDFHNFMKQSFFVMTDSGGIQEEAPALGKPVLVMRDT
HHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCEEEEECC
TERPEGVEAGTLKLTGLCEEDIYNEMTKLLTDKNEYDKMSEATNPYGDGHASERICDILS
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHH
KNL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]