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The map label for this gene is dnaA [H]

Identifier: 169823698

GI number: 169823698

Start: 365

End: 1822

Strand: Direct

Name: dnaA [H]

Synonym: FMG_0001

Alternate gene names: 169823698

Gene position: 365-1822 (Clockwise)

Preceding gene: NA

Following gene: 169823699

Centisome position: 0.02

GC content: 35.12

Gene sequence:

>1458_bases
ATGACCGACAAAGATGAACTCTGGTTAAAAATCTCTAACACATTTAAACAGGAAATGTCGGATTTGAACTTCAACACGTG
GATTGCACCATTAAAACCTCTTTATTTAACAAATACTGAATTTATTTTGCTTTCTCCAAATAGATTTACCAAAAAAACAA
TCTATAACAAATACTACGACGATATTCAAAAATACTTGGATTTCATCAGTAATGTCAAGAGAAAAGTAGTCATCATAGAC
CGTTACGAAATGGATAACTACAAAGACGAAAATATAATTCAAAACCAAAATATTGATGGTCAACGATCAATTCTAGTAAA
TGAAGATGAATCTGAGGAAAAATACAAGATTGAAGATCCTGTAGCAACCCAACCAGAACAAACACAAGAACAGGCAGAAG
AACAAACAGATTTTAGCCCTTACGGCAAGAATTTAATCGCCAAATACAAATTCGATACATTTGTAAAAGGCAAAAACAAC
GAACTAGCATTAGCTGCAGCACTTGCAGTCGCACAAAACCCAGCCACAGCATACAATCCATTGTTTATCCATGGAAAAGC
CGGATTGGGGAAGACTCACTTGATGCATGCCATTGCTCACGAAATACTTAAAAACAACCCAAAAGCGAGGGTTATTTACA
CTACGAGTGAATCATTTACAAACGAGCTTATTTCTTCAATTGGAGATAAATCTACGAAAAAGAATTCACAATTTAGACAA
AAATACCGAAATATAGACGTGCTTCTAATTGACGATATTCAATTTATTGCTGGAAAACAAGGTACACAAGAGGAGTTTTT
CCACACATTCAATGAATTGTACAACCACAACAAGCAAATCATCCTTTCCAGTGATAGACCTCCAAAAGAGATCAAAACAT
TGGAAGAGAGGTTGGTGTCTCGTTTTGAGTGGGGATTGATGGCAGACATTCAACCACCAGATTACGAAACGCGTGTGGCC
ATTGTAAACGAGTATTTGGATAGAAATAATACATCACTTCCACCTGAAATAATCGATTATATCGCTATGAATGTCAAAAG
CAATATTCGTGAGTTGGAAGGGGCAGTAATGAATGTTGTAGGTCAGAAAACTCTGATAGGAGATGGCAACATTACATTGG
ATTTGGCGAAAAACGTATTAAAACAACTTATCGCCGAAACTCAATTGAGACCTGTAACTATAGATTTAATCATTGAGTGC
GTGTGTGATAGATACAATGTCACTTTAGATGATCTTTTATCCAAGAAACGCTCCAAACAAATAGCATATCCAAGGCAAAT
AGCAATGTATGTGTCCAGAAAATTGTTGGATATTTCGTTGGTTAGTATTGCTTCAAGTTTTGGCAAGGATCACTCAACAG
TTATGCATGGAATCAAGAAAATTGAGAGTGATATCAAGAAAAATTCAGAATTTGACGAAGAAATTGAAAATCTAATCAAT
TACATTCAAAATTCTTAA

Upstream 100 bases:

>100_bases
AATTTTTTTTGTTTAATTTGAAAAATAGCTATTTATTTCATGTGGATAACTTATCATTTTGTGGATAAACTTGTTGATAA
CTAAAAAAACGAGGTGAAAA

Downstream 100 bases:

>100_bases
TATATTAAACTTAAAAATTGTGGATAAGTGTATTTTAAAGTTTTCTATCCACATTTTAATATTAATAACTATGTGGATAA
GTTGTTGATAACTTTAAAGT

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTDKDELWLKISNTFKQEMSDLNFNTWIAPLKPLYLTNTEFILLSPNRFTKKTIYNKYYDDIQKYLDFISNVKRKVVIID
RYEMDNYKDENIIQNQNIDGQRSILVNEDESEEKYKIEDPVATQPEQTQEQAEEQTDFSPYGKNLIAKYKFDTFVKGKNN
ELALAAALAVAQNPATAYNPLFIHGKAGLGKTHLMHAIAHEILKNNPKARVIYTTSESFTNELISSIGDKSTKKNSQFRQ
KYRNIDVLLIDDIQFIAGKQGTQEEFFHTFNELYNHNKQIILSSDRPPKEIKTLEERLVSRFEWGLMADIQPPDYETRVA
IVNEYLDRNNTSLPPEIIDYIAMNVKSNIRELEGAVMNVVGQKTLIGDGNITLDLAKNVLKQLIAETQLRPVTIDLIIEC
VCDRYNVTLDDLLSKKRSKQIAYPRQIAMYVSRKLLDISLVSIASSFGKDHSTVMHGIKKIESDIKKNSEFDEEIENLIN
YIQNS

Sequences:

>Translated_485_residues
MTDKDELWLKISNTFKQEMSDLNFNTWIAPLKPLYLTNTEFILLSPNRFTKKTIYNKYYDDIQKYLDFISNVKRKVVIID
RYEMDNYKDENIIQNQNIDGQRSILVNEDESEEKYKIEDPVATQPEQTQEQAEEQTDFSPYGKNLIAKYKFDTFVKGKNN
ELALAAALAVAQNPATAYNPLFIHGKAGLGKTHLMHAIAHEILKNNPKARVIYTTSESFTNELISSIGDKSTKKNSQFRQ
KYRNIDVLLIDDIQFIAGKQGTQEEFFHTFNELYNHNKQIILSSDRPPKEIKTLEERLVSRFEWGLMADIQPPDYETRVA
IVNEYLDRNNTSLPPEIIDYIAMNVKSNIRELEGAVMNVVGQKTLIGDGNITLDLAKNVLKQLIAETQLRPVTIDLIIEC
VCDRYNVTLDDLLSKKRSKQIAYPRQIAMYVSRKLLDISLVSIASSFGKDHSTVMHGIKKIESDIKKNSEFDEEIENLIN
YIQNS
>Mature_484_residues
TDKDELWLKISNTFKQEMSDLNFNTWIAPLKPLYLTNTEFILLSPNRFTKKTIYNKYYDDIQKYLDFISNVKRKVVIIDR
YEMDNYKDENIIQNQNIDGQRSILVNEDESEEKYKIEDPVATQPEQTQEQAEEQTDFSPYGKNLIAKYKFDTFVKGKNNE
LALAAALAVAQNPATAYNPLFIHGKAGLGKTHLMHAIAHEILKNNPKARVIYTTSESFTNELISSIGDKSTKKNSQFRQK
YRNIDVLLIDDIQFIAGKQGTQEEFFHTFNELYNHNKQIILSSDRPPKEIKTLEERLVSRFEWGLMADIQPPDYETRVAI
VNEYLDRNNTSLPPEIIDYIAMNVKSNIRELEGAVMNVVGQKTLIGDGNITLDLAKNVLKQLIAETQLRPVTIDLIIECV
CDRYNVTLDDLLSKKRSKQIAYPRQIAMYVSRKLLDISLVSIASSFGKDHSTVMHGIKKIESDIKKNSEFDEEIENLINY
IQNS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=485, Percent_Identity=38.5567010309278, Blast_Score=334, Evalue=6e-93,
Organism=Escherichia coli, GI226510964, Length=232, Percent_Identity=21.1206896551724, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 55905; Mature: 55774

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKDELWLKISNTFKQEMSDLNFNTWIAPLKPLYLTNTEFILLSPNRFTKKTIYNKYYD
CCCCCCEEEEEHHHHHHHHHHCCCCCEECCCCCEEECCCEEEEECCCCHHHHHHHHHHHH
DIQKYLDFISNVKRKVVIIDRYEMDNYKDENIIQNQNIDGQRSILVNEDESEEKYKIEDP
HHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCC
VATQPEQTQEQAEEQTDFSPYGKNLIAKYKFDTFVKGKNNELALAAALAVAQNPATAYNP
CCCCCHHHHHHHHHHCCCCCCCCCCEEEEECHHEECCCCCCCHHHHHHHHHCCCCCCCCC
LFIHGKAGLGKTHLMHAIAHEILKNNPKARVIYTTSESFTNELISSIGDKSTKKNSQFRQ
EEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHH
KYRNIDVLLIDDIQFIAGKQGTQEEFFHTFNELYNHNKQIILSSDRPPKEIKTLEERLVS
HHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
RFEWGLMADIQPPDYETRVAIVNEYLDRNNTSLPPEIIDYIAMNVKSNIRELEGAVMNVV
HHCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GQKTLIGDGNITLDLAKNVLKQLIAETQLRPVTIDLIIECVCDRYNVTLDDLLSKKRSKQ
CCEEEECCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCC
IAYPRQIAMYVSRKLLDISLVSIASSFGKDHSTVMHGIKKIESDIKKNSEFDEEIENLIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YIQNS
HHCCC
>Mature Secondary Structure 
TDKDELWLKISNTFKQEMSDLNFNTWIAPLKPLYLTNTEFILLSPNRFTKKTIYNKYYD
CCCCCEEEEEHHHHHHHHHHCCCCCEECCCCCEEECCCEEEEECCCCHHHHHHHHHHHH
DIQKYLDFISNVKRKVVIIDRYEMDNYKDENIIQNQNIDGQRSILVNEDESEEKYKIEDP
HHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCC
VATQPEQTQEQAEEQTDFSPYGKNLIAKYKFDTFVKGKNNELALAAALAVAQNPATAYNP
CCCCCHHHHHHHHHHCCCCCCCCCCEEEEECHHEECCCCCCCHHHHHHHHHCCCCCCCCC
LFIHGKAGLGKTHLMHAIAHEILKNNPKARVIYTTSESFTNELISSIGDKSTKKNSQFRQ
EEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHH
KYRNIDVLLIDDIQFIAGKQGTQEEFFHTFNELYNHNKQIILSSDRPPKEIKTLEERLVS
HHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHH
RFEWGLMADIQPPDYETRVAIVNEYLDRNNTSLPPEIIDYIAMNVKSNIRELEGAVMNVV
HHCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GQKTLIGDGNITLDLAKNVLKQLIAETQLRPVTIDLIIECVCDRYNVTLDDLLSKKRSKQ
CCEEEECCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCC
IAYPRQIAMYVSRKLLDISLVSIASSFGKDHSTVMHGIKKIESDIKKNSEFDEEIENLIN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YIQNS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA