| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is sppA [H]
Identifier: 169630869
GI number: 169630869
Start: 3844663
End: 3846414
Strand: Reverse
Name: sppA [H]
Synonym: MAB_3789c
Alternate gene names: 169630869
Gene position: 3846414-3844663 (Counterclockwise)
Preceding gene: 169630873
Following gene: 169630868
Centisome position: 75.91
GC content: 66.04
Gene sequence:
>1752_bases ATGTTTGCGTTCACCACGCCCACAGACGTCCACGACCTGCTGGCCAAGGTCGACACCGCACGTCATCGGGGAGTGCCGAG GGACTGCATTCTGGAGCTAGACCTGCTTGAGGTGCCGCCGGAGTCGGTCCACCTCGACCCGTTGGGTCTGGTGCTCTCGG GTGGGAGCAGACCACTGTCGCTGCGGCACACCATCGCCGCCATCCACCGCGCCATCGAGGATCCGCGGGTGGCTGGGCTG ATCGCTCGGGTACAGATACCGCCGGCCGCGGCTGGCGCCGTCCAGGAGTTGCGGGCCGCTATCGAGGCGTTCAGCGCCGT CAAACCCAGCCTGGCATGGTCAGAGACGTATCCGAGCACGCTTGCCTATTACCTTGCGTCGGCGTTCGGCGAGGTGTGGA TGCAACCGTCCGGAACGGTGGGGCTCATCGGATTCGCGGCCAAGGGCACGTTCCTGCGCGGTGCGCTCGACAAGGCCGGC GTAGAGGCACAGTTCCTCACCCGTGGCCAATACAAGTCGGCGGCAAATCTTTTCACCGAAGACGGCTACACCGACGCGCA GCGGGAGGCCGATGGACGATTGCTGGAGAGCCTGTCGGAACAGGTTCGGGACAGTGTGGCGGTGTCGCGCAAGCTCGACC CCGCCGAAGTGGATGCCCTGGCGGACCGGGCGCCGCTGCGTCGTACCGATGCGGTCGCCGGTGGATTGGTAGACCGCATC GGCTATCGCGATGAGGCCTACGCGCGTATTGGTGAGCTCATCGGCCTGCAAGATGACAGGGATCCTCCGCTGCTGTATTT GGCGCGTTACGCCCGTGCCACCAAGCCGCAAGTACCCAGCCTGTCGTCGCTCCCGGGGCGCCCGTCGCGGCCGGCCATCG GCGTAGTGACGCTGGCGGGCCCCATCGTGAGCGGCCGCAGCGGCCCACGGCTTTTTCCACCGGGACCGGCCAGTGGTGGT GATGTGATTGCCGAGGCGCTCCGCGATGCCGTCGCCGACGATTCGGTCGCCGCCATAGTGCTGCGGGTAGACAGTCCCGG CGGTTCGGTCAACGGTTCGGAAACCATTTGGCGGGAGGTAGTCCGCGCGCGTGAGGCGGGTAAACCTGTCGTGGTGTCCA TGGGTTCGGTGGCGGGTTCGGGCGGTTACTACGTCGCCATGTCAGCCGATGCGATCATCGCCAACCCGGGTACCGTCACC GGGTCCATCGGCGTGCTGACCGGAAAGTTCATCACCAAGGGTCTCAAGGAGAAGCTCGGCGTCGGTTCGGACAGCTTGCG CACCAACGCCAATGCCGACGCATGGTCGAGTAACGAACCGTTCACCGACGAGCAGCGCGATCTTGTCGAGGCCGAGATCG ACATGCATTACGAAGACTTCGTGCAGCGGGTCGCCGACGGACGCAATCTGACCGTCGATGCCGTCAAAGCAGTTGCCCAG GGCAGGATCTGGTCTGGCAAGGACGCGTTGGAGCACGGATTGGTCGACGAGCTCGGCGGCTTCCGGGAGGCAGTGGCAAA GGCCAAGCAGCTCGCGGACATCGGTGCCGACGACAATGTCCGGATCGCGAACTTCCCGAGCTCGCCGCTGTCGTCGCTGC TGCGGCAGCGGTCATCGTCGCAGCCGGCCGCGGCGGCCGTCACTGACGCGGTACTGGGCCGGGTGGCGCAGCTGGCGGTG GAGACGGTGCAGCGTGCTCAGCGAACCCTCGGCAGCGCGCAGGCGATGATGTTGGGCGACTACCGCTTTTAG
Upstream 100 bases:
>100_bases CCCCTCCGCCAGCGAATGGTTCCGACCCTACGCGCCGCGTGGTACGGGAGCACGGATTTGTGGTCGGCGGGATTACCGCA TTCGTCGGTACGCTCAAGAC
Downstream 100 bases:
>100_bases TGCCCCAGCGCGTTTCGCCTGGGCGGGGGCCCGCACCCGCTAACGTGTCGTGTGCAGGCGGCAGAAGGGGCGTGGCGTGA ACACCGAACTGACCGTATTT
Product: protease IV SppA
Products: NA
Alternate protein names: Endopeptidase IV; Protease IV homolog; Signal peptide peptidase [H]
Number of amino acids: Translated: 583; Mature: 583
Protein sequence:
>583_residues MFAFTTPTDVHDLLAKVDTARHRGVPRDCILELDLLEVPPESVHLDPLGLVLSGGSRPLSLRHTIAAIHRAIEDPRVAGL IARVQIPPAAAGAVQELRAAIEAFSAVKPSLAWSETYPSTLAYYLASAFGEVWMQPSGTVGLIGFAAKGTFLRGALDKAG VEAQFLTRGQYKSAANLFTEDGYTDAQREADGRLLESLSEQVRDSVAVSRKLDPAEVDALADRAPLRRTDAVAGGLVDRI GYRDEAYARIGELIGLQDDRDPPLLYLARYARATKPQVPSLSSLPGRPSRPAIGVVTLAGPIVSGRSGPRLFPPGPASGG DVIAEALRDAVADDSVAAIVLRVDSPGGSVNGSETIWREVVRAREAGKPVVVSMGSVAGSGGYYVAMSADAIIANPGTVT GSIGVLTGKFITKGLKEKLGVGSDSLRTNANADAWSSNEPFTDEQRDLVEAEIDMHYEDFVQRVADGRNLTVDAVKAVAQ GRIWSGKDALEHGLVDELGGFREAVAKAKQLADIGADDNVRIANFPSSPLSSLLRQRSSSQPAAAAVTDAVLGRVAQLAV ETVQRAQRTLGSAQAMMLGDYRF
Sequences:
>Translated_583_residues MFAFTTPTDVHDLLAKVDTARHRGVPRDCILELDLLEVPPESVHLDPLGLVLSGGSRPLSLRHTIAAIHRAIEDPRVAGL IARVQIPPAAAGAVQELRAAIEAFSAVKPSLAWSETYPSTLAYYLASAFGEVWMQPSGTVGLIGFAAKGTFLRGALDKAG VEAQFLTRGQYKSAANLFTEDGYTDAQREADGRLLESLSEQVRDSVAVSRKLDPAEVDALADRAPLRRTDAVAGGLVDRI GYRDEAYARIGELIGLQDDRDPPLLYLARYARATKPQVPSLSSLPGRPSRPAIGVVTLAGPIVSGRSGPRLFPPGPASGG DVIAEALRDAVADDSVAAIVLRVDSPGGSVNGSETIWREVVRAREAGKPVVVSMGSVAGSGGYYVAMSADAIIANPGTVT GSIGVLTGKFITKGLKEKLGVGSDSLRTNANADAWSSNEPFTDEQRDLVEAEIDMHYEDFVQRVADGRNLTVDAVKAVAQ GRIWSGKDALEHGLVDELGGFREAVAKAKQLADIGADDNVRIANFPSSPLSSLLRQRSSSQPAAAAVTDAVLGRVAQLAV ETVQRAQRTLGSAQAMMLGDYRF >Mature_583_residues MFAFTTPTDVHDLLAKVDTARHRGVPRDCILELDLLEVPPESVHLDPLGLVLSGGSRPLSLRHTIAAIHRAIEDPRVAGL IARVQIPPAAAGAVQELRAAIEAFSAVKPSLAWSETYPSTLAYYLASAFGEVWMQPSGTVGLIGFAAKGTFLRGALDKAG VEAQFLTRGQYKSAANLFTEDGYTDAQREADGRLLESLSEQVRDSVAVSRKLDPAEVDALADRAPLRRTDAVAGGLVDRI GYRDEAYARIGELIGLQDDRDPPLLYLARYARATKPQVPSLSSLPGRPSRPAIGVVTLAGPIVSGRSGPRLFPPGPASGG DVIAEALRDAVADDSVAAIVLRVDSPGGSVNGSETIWREVVRAREAGKPVVVSMGSVAGSGGYYVAMSADAIIANPGTVT GSIGVLTGKFITKGLKEKLGVGSDSLRTNANADAWSSNEPFTDEQRDLVEAEIDMHYEDFVQRVADGRNLTVDAVKAVAQ GRIWSGKDALEHGLVDELGGFREAVAKAKQLADIGADDNVRIANFPSSPLSSLLRQRSSSQPAAAAVTDAVLGRVAQLAV ETVQRAQRTLGSAQAMMLGDYRF
Specific function: Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane [H]
COG id: COG0616
COG function: function code OU; Periplasmic serine proteases (ClpP class)
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S49 family [H]
Homologues:
Organism=Escherichia coli, GI1788064, Length=498, Percent_Identity=33.9357429718875, Blast_Score=214, Evalue=2e-56, Organism=Escherichia coli, GI1787527, Length=175, Percent_Identity=31.4285714285714, Blast_Score=77, Evalue=4e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004634 - InterPro: IPR004635 - InterPro: IPR002142 [H]
Pfam domain/function: PF01343 Peptidase_S49 [H]
EC number: 3.4.21.-
Molecular weight: Translated: 61658; Mature: 61658
Theoretical pI: Translated: 5.30; Mature: 5.30
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 1.4 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFAFTTPTDVHDLLAKVDTARHRGVPRDCILELDLLEVPPESVHLDPLGLVLSGGSRPLS CCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEHHHHCCCCCEECCCCEEEEECCCCCCH LRHTIAAIHRAIEDPRVAGLIARVQIPPAAAGAVQELRAAIEAFSAVKPSLAWSETYPST HHHHHHHHHHHHCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH LAYYLASAFGEVWMQPSGTVGLIGFAAKGTFLRGALDKAGVEAQFLTRGQYKSAANLFTE HHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHCC DGYTDAQREADGRLLESLSEQVRDSVAVSRKLDPAEVDALADRAPLRRTDAVAGGLVDRI CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH GYRDEAYARIGELIGLQDDRDPPLLYLARYARATKPQVPSLSSLPGRPSRPAIGVVTLAG CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECC PIVSGRSGPRLFPPGPASGGDVIAEALRDAVADDSVAAIVLRVDSPGGSVNGSETIWREV CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHH VRAREAGKPVVVSMGSVAGSGGYYVAMSADAIIANPGTVTGSIGVLTGKFITKGLKEKLG HHHHHCCCCEEEEECCCCCCCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHC VGSDSLRTNANADAWSSNEPFTDEQRDLVEAEIDMHYEDFVQRVADGRNLTVDAVKAVAQ CCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHC GRIWSGKDALEHGLVDELGGFREAVAKAKQLADIGADDNVRIANFPSSPLSSLLRQRSSS CCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCC QPAAAAVTDAVLGRVAQLAVETVQRAQRTLGSAQAMMLGDYRF CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC >Mature Secondary Structure MFAFTTPTDVHDLLAKVDTARHRGVPRDCILELDLLEVPPESVHLDPLGLVLSGGSRPLS CCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEHHHHCCCCCEECCCCEEEEECCCCCCH LRHTIAAIHRAIEDPRVAGLIARVQIPPAAAGAVQELRAAIEAFSAVKPSLAWSETYPST HHHHHHHHHHHHCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH LAYYLASAFGEVWMQPSGTVGLIGFAAKGTFLRGALDKAGVEAQFLTRGQYKSAANLFTE HHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHCC DGYTDAQREADGRLLESLSEQVRDSVAVSRKLDPAEVDALADRAPLRRTDAVAGGLVDRI CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH GYRDEAYARIGELIGLQDDRDPPLLYLARYARATKPQVPSLSSLPGRPSRPAIGVVTLAG CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECC PIVSGRSGPRLFPPGPASGGDVIAEALRDAVADDSVAAIVLRVDSPGGSVNGSETIWREV CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHH VRAREAGKPVVVSMGSVAGSGGYYVAMSADAIIANPGTVTGSIGVLTGKFITKGLKEKLG HHHHHCCCCEEEEECCCCCCCCEEEEEECCEEEECCCCCCCCHHHHHHHHHHHHHHHHHC VGSDSLRTNANADAWSSNEPFTDEQRDLVEAEIDMHYEDFVQRVADGRNLTVDAVKAVAQ CCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHC GRIWSGKDALEHGLVDELGGFREAVAKAKQLADIGADDNVRIANFPSSPLSSLLRQRSSS CCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCC QPAAAAVTDAVLGRVAQLAVETVQRAQRTLGSAQAMMLGDYRF CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]