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The map label for this gene is metX [H]

Identifier: 169630767

GI number: 169630767

Start: 3743570

End: 3744724

Strand: Direct

Name: metX [H]

Synonym: MAB_3688

Alternate gene names: 169630767

Gene position: 3743570-3744724 (Clockwise)

Preceding gene: 169630766

Following gene: 169630768

Centisome position: 73.88

GC content: 67.79

Gene sequence:

>1155_bases
GTGACCATCGAACAGCAGCTTCCGGTCCCCCACATCGCCCTACCCCAGGGCGATGAGATCGCCTATGTACCAATAGGTTC
GATCACTCTGGAAAGCGGTGCTGTGATCGACGACGTGACCATCGCGGTACAGAGCTGGGGCGAGCTCTCACCCCGGCGCG
ACAACGTGGTGTTCGTGTGCCACGCGCTCACCGCCGATTCTCATGTGGTCGGACCCGCCGGGCCCGACCACATCACCGGC
GGCTGGTGGGAGGGGATCATCGGCCCGGGCGCGGCGATCGACACCGATCACTGGTGCGCCGTGGCCACCAATGTCCTGGG
AGGCTGCCGAGGCACCACCGGCCCCACTTCCCTCGCCCGCGACGGCAAGCCCTGGGGTTCACGATTCCCCGAAGTCTCGG
TGCGCGACCAGGTGAACGCCGACGTCGCCGCCCTCGCCCAGCTGGGCATCACCGAGGTCGCGGCCGTCGTCGGCGGTTCG
ATGGGCGGCGCCCGTGCGCTGGAATGGGCTGTGATGCATCCGGATGCGGTTCGTGCGGCCCTGGTACTGGCAGTGGGCGC
GCGGGCCACCGGCGACCAGATCGGCACGCAGAGTACGCAGATCGCCGCCATCCAGACTGATCCGGACTGGCAGGGTGGCG
ACTACCACGGCAGCGGACGCAGCCCCGGGAAGGGACTGAATCTGGCCCGGCGGATCGCGCATCTGACCTACCGCGGCGAG
GTCGAATTGGACACCCGGTTCGGCAACGACCCGCAGGTCGGCCCGGACGGCCCCGAAGACCCCTGGGCGGATGGCCGATA
CGCGGTGCAGAGCTACCTGGAACATCAGGGCAACAAGTTCGTTCGGCGCTTCGACGCGGGCAGCTACGTCATCCTGACCG
AGTCGCTCAACCGCCACGACGTCGGTCGGGGCCGCGGCGGTGTGGAGAAGGCGCTACGCGGCTGCCCGGTCCCTGTCGTG
GTCGGCGGTATCACCTCCGACCGGCTCTACCCGCTGCGACTGCAGGAGGAATTAGCGGACCTGCTGCCTGGTTGTACCGG
CTTGCGGGTGGTCGAGTCGGTGCACGGCCATGACGCATTCCTCATCGAGTTCGACGCGGTGAGCGAGTTGGTGCGGGAAA
CGCTCGCACTGGCCAAGGCAACACAGGCTTCGTAA

Upstream 100 bases:

>100_bases
TGGCCGTCGGCATCGAGGGCATCGACGACATCCTGGCCGACCTGGAGTCCGGATTCACGGCCGTACGCAGGCTCAAACAA
CCCGCGGCGGTGGCATCATC

Downstream 100 bases:

>100_bases
ACACCGAACCCAGAGGGAGCGCGAATGCCGGACGCACAGGCAGAACCATCGCTTTCGTTCGGTTCGCAGGCAGCCGCCTA
CGAACGAGGCCGGCCCTCCT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTIEQQLPVPHIALPQGDEIAYVPIGSITLESGAVIDDVTIAVQSWGELSPRRDNVVFVCHALTADSHVVGPAGPDHITG
GWWEGIIGPGAAIDTDHWCAVATNVLGGCRGTTGPTSLARDGKPWGSRFPEVSVRDQVNADVAALAQLGITEVAAVVGGS
MGGARALEWAVMHPDAVRAALVLAVGARATGDQIGTQSTQIAAIQTDPDWQGGDYHGSGRSPGKGLNLARRIAHLTYRGE
VELDTRFGNDPQVGPDGPEDPWADGRYAVQSYLEHQGNKFVRRFDAGSYVILTESLNRHDVGRGRGGVEKALRGCPVPVV
VGGITSDRLYPLRLQEELADLLPGCTGLRVVESVHGHDAFLIEFDAVSELVRETLALAKATQAS

Sequences:

>Translated_384_residues
MTIEQQLPVPHIALPQGDEIAYVPIGSITLESGAVIDDVTIAVQSWGELSPRRDNVVFVCHALTADSHVVGPAGPDHITG
GWWEGIIGPGAAIDTDHWCAVATNVLGGCRGTTGPTSLARDGKPWGSRFPEVSVRDQVNADVAALAQLGITEVAAVVGGS
MGGARALEWAVMHPDAVRAALVLAVGARATGDQIGTQSTQIAAIQTDPDWQGGDYHGSGRSPGKGLNLARRIAHLTYRGE
VELDTRFGNDPQVGPDGPEDPWADGRYAVQSYLEHQGNKFVRRFDAGSYVILTESLNRHDVGRGRGGVEKALRGCPVPVV
VGGITSDRLYPLRLQEELADLLPGCTGLRVVESVHGHDAFLIEFDAVSELVRETLALAKATQAS
>Mature_383_residues
TIEQQLPVPHIALPQGDEIAYVPIGSITLESGAVIDDVTIAVQSWGELSPRRDNVVFVCHALTADSHVVGPAGPDHITGG
WWEGIIGPGAAIDTDHWCAVATNVLGGCRGTTGPTSLARDGKPWGSRFPEVSVRDQVNADVAALAQLGITEVAAVVGGSM
GGARALEWAVMHPDAVRAALVLAVGARATGDQIGTQSTQIAAIQTDPDWQGGDYHGSGRSPGKGLNLARRIAHLTYRGEV
ELDTRFGNDPQVGPDGPEDPWADGRYAVQSYLEHQGNKFVRRFDAGSYVILTESLNRHDVGRGRGGVEKALRGCPVPVVV
GGITSDRLYPLRLQEELADLLPGCTGLRVVESVHGHDAFLIEFDAVSELVRETLALAKATQAS

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=241, Percent_Identity=34.8547717842324, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 40583; Mature: 40452

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEQQLPVPHIALPQGDEIAYVPIGSITLESGAVIDDVTIAVQSWGELSPRRDNVVFVC
CCCCCCCCCCEEECCCCCCEEEEECCCEEECCCCEEEHEEEEEHHCCCCCCCCCCEEEEE
HALTADSHVVGPAGPDHITGGWWEGIIGPGAAIDTDHWCAVATNVLGGCRGTTGPTSLAR
EEECCCCEEECCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHCC
DGKPWGSRFPEVSVRDQVNADVAALAQLGITEVAAVVGGSMGGARALEWAVMHPDAVRAA
CCCCHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCHHHHHH
LVLAVGARATGDQIGTQSTQIAAIQTDPDWQGGDYHGSGRSPGKGLNLARRIAHLTYRGE
HHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCC
VELDTRFGNDPQVGPDGPEDPWADGRYAVQSYLEHQGNKFVRRFDAGSYVILTESLNRHD
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHEECCCCEEEEECCCCCCC
VGRGRGGVEKALRGCPVPVVVGGITSDRLYPLRLQEELADLLPGCTGLRVVESVHGHDAF
CCCCCCCHHHHHHCCCCCEEEECCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHCCCCEE
LIEFDAVSELVRETLALAKATQAS
EEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIEQQLPVPHIALPQGDEIAYVPIGSITLESGAVIDDVTIAVQSWGELSPRRDNVVFVC
CCCCCCCCCEEECCCCCCEEEEECCCEEECCCCEEEHEEEEEHHCCCCCCCCCCEEEEE
HALTADSHVVGPAGPDHITGGWWEGIIGPGAAIDTDHWCAVATNVLGGCRGTTGPTSLAR
EEECCCCEEECCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHCC
DGKPWGSRFPEVSVRDQVNADVAALAQLGITEVAAVVGGSMGGARALEWAVMHPDAVRAA
CCCCHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCHHHHHH
LVLAVGARATGDQIGTQSTQIAAIQTDPDWQGGDYHGSGRSPGKGLNLARRIAHLTYRGE
HHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCC
VELDTRFGNDPQVGPDGPEDPWADGRYAVQSYLEHQGNKFVRRFDAGSYVILTESLNRHD
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHEECCCCEEEEECCCCCCC
VGRGRGGVEKALRGCPVPVVVGGITSDRLYPLRLQEELADLLPGCTGLRVVESVHGHDAF
CCCCCCCHHHHHHCCCCCEEEECCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHCCCCEE
LIEFDAVSELVRETLALAKATQAS
EEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]