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The map label for this gene is pgm [C]

Identifier: 169630740

GI number: 169630740

Start: 3714184

End: 3715797

Strand: Direct

Name: pgm [C]

Synonym: MAB_3661

Alternate gene names: 169630740

Gene position: 3714184-3715797 (Clockwise)

Preceding gene: 169630739

Following gene: 169630742

Centisome position: 73.3

GC content: 65.68

Gene sequence:

>1614_bases
ATGACTGTGGCAGCAGAAACGATCCAGGAGTGGATCGACCACGACCCGGATCCCCAGACCGTCGCCGAGCTGCGCGCGTG
CTCCGAAGACGAGCTTGCCCAGCGTTTCTCGGATCCACTGGTGTTCGGCACGGCGGGCCTGCGCGGCCCCGTGCGCGGCG
GCCCGAATGGAATGAACCTGGCGGTGGTGTTGCGCACCACCTATGGGCTGGCCAAGGTCCTCAAGGATCGATGCCTGGGC
GGCTCCACCGTGGTGGTGGGCCGCGACGCCCGCCACGGATCCGAGAAGTTTGCGCTAGGCGCGGCCGAAGTCCTTGCTGC
CGAAGGATTCACGGTGGTGTTGTTACCCCGTCCGCTGCCGACGCCGGTGCTGGCCTTCGCGGTGCGGCAGGTGGATGCGG
CGGCAGGCATCCAAATCACCGCATCCCATAATCCGCCCGCGGACAACGGCTACAAGGTGTACTGGTCGGGCGGAGCCCAG
ATCATCTCCCCCACCGATCGTGAAATCGAAGCGGCAACGGCGGCAGCGCCTTTCGCCGATCAAATTCCCCGCACCCCGGT
CGAGCCCACCGGCGAGTCCTTGATCGATGCCTATGTTCAGCGCGCCGCGACGGTGCGCCGCGGCGCGGGCAACTTGCGTG
TCGTCCTCACCGCACTTCACGGGGTCGGTGGCGCCACCGCCGTGGCCACCCTGAACGCCGCGGGCATCACCGACATCCAC
CTGGTGGACGAGCAGTTCCAGCCGAATCCGGACTTTCCCACTGTCGAGTTTCCGAATCCGGAAGAACGAGGCGCCTCCGA
CGCGGTGCTGGCCCGGGCCGCCGAGGTGGACGCGGCCCTGGCGATCGCCCTCGATCCCGACGCCGATCGATGCGCCATCG
GAGTCCCCACCACCACGGGTTGGCGCATGTTGTCTGGAGATGAAACCGGTTGGCTGCTGGGCGATTACATTCTTTCCACA
CAACCGGATTCCTCGATTCCTCCGGTGGTTGCCAGCACGGTGGTCTCCTCACGCATGCTGGCGCGCATCGCGGCATCCCT
CGGCGCCCGCCATGTGGAAACCCTTACGGGGTTCAAATGGCTGGTACGCGCGGCAGATTCCGATCTCGTCTATGCCTATG
AGGAAGCCATCGGTCATTGCGTGGATCCGGTGGCGGTCCGCGACAAGGACGGCATCTCGGCGGCGGTGCTCGCCTGCGAC
CTGGTCACCCATCTACGCGAGCTCGGCACCAGTGTGGAGGAAAAACTCGAGAACCTTGCGATCCGGCATGGCATCCACGT
GACCTCTCAGGTGTCACGGCGCATGGACTCACTCGAGGACATCGAAGCGATGATGACCCGACTGCGCCAGAACATCCCCG
CTGCCTTGTCCGGATTTCCCATCACCGCGGAAGATCTTCTGGAGCGACGCGGCCAGCAGCGCACCGACGCGGTGGTCCTC
TCGGGCGAGATCGGCGGGTCGTCCATCCGTCTGGTACTCCGGCCGTCGGGAACCGAACCAAAAGTCAAGTGCTACATCGA
GGTCCGCGAACCCGTGATCACCGACCCCACCGTGGCGCGGATCTGGGCCGGGGTGGTGGTCTCCGAGCTGGAGGCTTACG
CCCGGAACATCTGA

Upstream 100 bases:

>100_bases
GAATGACCGGCGAATCCCTGAATCATGAGGAGGTGCTGGCGGCGGGCCGAGCGTCGGCCACCCGCATGGGCCAACTTCTA
CGCGCGGTGATTGGTCGGCT

Downstream 100 bases:

>100_bases
CGCGGCCCGAGCTATCGGGGCCCGAACTGGCGATCACCGGCATCGCCCAACCCGGGCACGATGTAGGCGGCGTCGTTGAG
ACCCTCGTCGATCGTGGCAG

Product: phosphomannomutase PmmB

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MTVAAETIQEWIDHDPDPQTVAELRACSEDELAQRFSDPLVFGTAGLRGPVRGGPNGMNLAVVLRTTYGLAKVLKDRCLG
GSTVVVGRDARHGSEKFALGAAEVLAAEGFTVVLLPRPLPTPVLAFAVRQVDAAAGIQITASHNPPADNGYKVYWSGGAQ
IISPTDREIEAATAAAPFADQIPRTPVEPTGESLIDAYVQRAATVRRGAGNLRVVLTALHGVGGATAVATLNAAGITDIH
LVDEQFQPNPDFPTVEFPNPEERGASDAVLARAAEVDAALAIALDPDADRCAIGVPTTTGWRMLSGDETGWLLGDYILST
QPDSSIPPVVASTVVSSRMLARIAASLGARHVETLTGFKWLVRAADSDLVYAYEEAIGHCVDPVAVRDKDGISAAVLACD
LVTHLRELGTSVEEKLENLAIRHGIHVTSQVSRRMDSLEDIEAMMTRLRQNIPAALSGFPITAEDLLERRGQQRTDAVVL
SGEIGGSSIRLVLRPSGTEPKVKCYIEVREPVITDPTVARIWAGVVVSELEAYARNI

Sequences:

>Translated_537_residues
MTVAAETIQEWIDHDPDPQTVAELRACSEDELAQRFSDPLVFGTAGLRGPVRGGPNGMNLAVVLRTTYGLAKVLKDRCLG
GSTVVVGRDARHGSEKFALGAAEVLAAEGFTVVLLPRPLPTPVLAFAVRQVDAAAGIQITASHNPPADNGYKVYWSGGAQ
IISPTDREIEAATAAAPFADQIPRTPVEPTGESLIDAYVQRAATVRRGAGNLRVVLTALHGVGGATAVATLNAAGITDIH
LVDEQFQPNPDFPTVEFPNPEERGASDAVLARAAEVDAALAIALDPDADRCAIGVPTTTGWRMLSGDETGWLLGDYILST
QPDSSIPPVVASTVVSSRMLARIAASLGARHVETLTGFKWLVRAADSDLVYAYEEAIGHCVDPVAVRDKDGISAAVLACD
LVTHLRELGTSVEEKLENLAIRHGIHVTSQVSRRMDSLEDIEAMMTRLRQNIPAALSGFPITAEDLLERRGQQRTDAVVL
SGEIGGSSIRLVLRPSGTEPKVKCYIEVREPVITDPTVARIWAGVVVSELEAYARNI
>Mature_536_residues
TVAAETIQEWIDHDPDPQTVAELRACSEDELAQRFSDPLVFGTAGLRGPVRGGPNGMNLAVVLRTTYGLAKVLKDRCLGG
STVVVGRDARHGSEKFALGAAEVLAAEGFTVVLLPRPLPTPVLAFAVRQVDAAAGIQITASHNPPADNGYKVYWSGGAQI
ISPTDREIEAATAAAPFADQIPRTPVEPTGESLIDAYVQRAATVRRGAGNLRVVLTALHGVGGATAVATLNAAGITDIHL
VDEQFQPNPDFPTVEFPNPEERGASDAVLARAAEVDAALAIALDPDADRCAIGVPTTTGWRMLSGDETGWLLGDYILSTQ
PDSSIPPVVASTVVSSRMLARIAASLGARHVETLTGFKWLVRAADSDLVYAYEEAIGHCVDPVAVRDKDGISAAVLACDL
VTHLRELGTSVEEKLENLAIRHGIHVTSQVSRRMDSLEDIEAMMTRLRQNIPAALSGFPITAEDLLERRGQQRTDAVVLS
GEIGGSSIRLVLRPSGTEPKVKCYIEVREPVITDPTVARIWAGVVVSELEAYARNI

Specific function: This Enzyme Participates In Both The Breakdown And Synthesis Of Glucose. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=580, Percent_Identity=32.9310344827586, Blast_Score=253, Evalue=4e-67,
Organism=Homo sapiens, GI31377548, Length=560, Percent_Identity=31.0714285714286, Blast_Score=223, Evalue=4e-58,
Organism=Escherichia coli, GI1786904, Length=505, Percent_Identity=26.9306930693069, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788361, Length=442, Percent_Identity=23.7556561085973, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71993870, Length=576, Percent_Identity=30.7291666666667, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71993878, Length=308, Percent_Identity=33.7662337662338, Blast_Score=160, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323934, Length=574, Percent_Identity=30.6620209059233, Blast_Score=231, Evalue=2e-61,
Organism=Drosophila melanogaster, GI20129809, Length=562, Percent_Identity=32.2064056939502, Blast_Score=241, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24651977, Length=482, Percent_Identity=34.2323651452282, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24653722, Length=482, Percent_Identity=29.8755186721992, Blast_Score=196, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 57094; Mature: 56963

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAAETIQEWIDHDPDPQTVAELRACSEDELAQRFSDPLVFGTAGLRGPVRGGPNGMNL
CCCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEE
AVVLRTTYGLAKVLKDRCLGGSTVVVGRDARHGSEKFALGAAEVLAAEGFTVVLLPRPLP
EEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
TPVLAFAVRQVDAAAGIQITASHNPPADNGYKVYWSGGAQIISPTDREIEAATAAAPFAD
HHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHCCCCHH
QIPRTPVEPTGESLIDAYVQRAATVRRGAGNLRVVLTALHGVGGATAVATLNAAGITDIH
HCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCHHHHEEECCCCCEEEE
LVDEQFQPNPDFPTVEFPNPEERGASDAVLARAAEVDAALAIALDPDADRCAIGVPTTTG
EECCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCEEEEEEECCCCCCEEECCCCCCC
WRMLSGDETGWLLGDYILSTQPDSSIPPVVASTVVSSRMLARIAASLGARHVETLTGFKW
CEEECCCCCCEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LVRAADSDLVYAYEEAIGHCVDPVAVRDKDGISAAVLACDLVTHLRELGTSVEEKLENLA
HHHHCCCCEEHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IRHGIHVTSQVSRRMDSLEDIEAMMTRLRQNIPAALSGFPITAEDLLERRGQQRTDAVVL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCCCEEEE
SGEIGGSSIRLVLRPSGTEPKVKCYIEVREPVITDPTVARIWAGVVVSELEAYARNI
EECCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVAAETIQEWIDHDPDPQTVAELRACSEDELAQRFSDPLVFGTAGLRGPVRGGPNGMNL
CCCHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEE
AVVLRTTYGLAKVLKDRCLGGSTVVVGRDARHGSEKFALGAAEVLAAEGFTVVLLPRPLP
EEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCC
TPVLAFAVRQVDAAAGIQITASHNPPADNGYKVYWSGGAQIISPTDREIEAATAAAPFAD
HHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCHHHHHHHCCCCHH
QIPRTPVEPTGESLIDAYVQRAATVRRGAGNLRVVLTALHGVGGATAVATLNAAGITDIH
HCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHCCCCHHHHEEECCCCCEEEE
LVDEQFQPNPDFPTVEFPNPEERGASDAVLARAAEVDAALAIALDPDADRCAIGVPTTTG
EECCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHCCEEEEEEECCCCCCEEECCCCCCC
WRMLSGDETGWLLGDYILSTQPDSSIPPVVASTVVSSRMLARIAASLGARHVETLTGFKW
CEEECCCCCCEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LVRAADSDLVYAYEEAIGHCVDPVAVRDKDGISAAVLACDLVTHLRELGTSVEEKLENLA
HHHHCCCCEEHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IRHGIHVTSQVSRRMDSLEDIEAMMTRLRQNIPAALSGFPITAEDLLERRGQQRTDAVVL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCCCCCCCEEEE
SGEIGGSSIRLVLRPSGTEPKVKCYIEVREPVITDPTVARIWAGVVVSELEAYARNI
EECCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]