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The map label for this gene is virS [H]

Identifier: 169630702

GI number: 169630702

Start: 3671917

End: 3672936

Strand: Direct

Name: virS [H]

Synonym: MAB_3623

Alternate gene names: 169630702

Gene position: 3671917-3672936 (Clockwise)

Preceding gene: 169630696

Following gene: 169630710

Centisome position: 72.46

GC content: 66.76

Gene sequence:

>1020_bases
ATGAACATCCGACTGGTTCGGTTCGCGGCGTTGAGCGGGTACGTCGACGTAGCCAGGGCATCCGGTCTGGATCCGGCGCG
AATGATGCGGGAGCACGGTCTGGACCCGGCGGGCCTCGCCCAACCCGATCGCCGGGTGGCCGCCGACGCCGTCATCGCGC
TCCTGGAGGCCTCCGCCGACGCCAGCGGAGTGGATGACTTCGGTCTCAGACTCGCCGAACGGAGGCGACTATCCAGCCTC
GGCCCGCTCAGCCTGGCGCTACGGGAACAGCCCACCGTGCGCGACGTCGTCGCGATGCTGTGTCGGTACGAATCGATGTA
CAACGAGTCCTTGCGGATCCGGGTTGTCGAGCGCGACGGAATCGCCGCCGTCCGGCTGGCCCTTGACGCCGGGGGTGCCG
CCGCCACCCAATCCACCGATTTGGCACTCGCCGCTCTTGCCGGAGTGCTACGCACCTTCTTGAGCAACACGTGGCATCCG
CTGCGGGTCAATCTGCGCCGGCCGAAGCCCTCGGCCCCCGCCATGCATCACCGCATCTTCGGGCCACGCATCGAGTTCGC
GCAGCAGCTCGACGAGATCGTCGTCTACACCTCCGATCTCGACCGCCGGAACGACAGTTTCGACCCGCTACTGCGCCAGT
ACAGCCAGGCGGTCCTTGAGCCGCCGGAAAGGCCTGGCGACACGACAACCACCGATCGTGTCCGAGATCTCATCGAGGTG
CTGCTGCCCCTCGGCCGTTGCTCGGTCGAACAGGTCGCCCAGGGCCTGGGAGTCGACCGGCGGACGGTTCACCGGCAGCT
GGCCAGCGAGGGCACGAGCTTCAGCGCTCTGTTGGACACCATCCGGCTCGATTTGGCCGATCACCTCGTCACGAGCGATC
GCCACAGCCTGACCGAGATCTCCGAAATGCTGGCGTTTTCATCACCAAGCAACTTCAGTCGGTGGTTTCGCGGGCATCGC
GCGATGAGCCCCCGCACCTGGCGAAACCTGCGTGCCGACGCGATCGCCGCGCACAGCTGA

Upstream 100 bases:

>100_bases
GGCCCGCCTTTCATCCGTCTCGTGTGTATCTCCGACGTTAGGGAGGCGAGAGGGGGGATACTTATCTTTACGAGACAGGT
TTCTATTCATTTAGGGACAT

Downstream 100 bases:

>100_bases
ACCGGCGGCCAATACTCAACGAGGTCCGCCGACCGCTTCGCACTGCCCTGCCATCTTCCGTACACTCGCCATTTGTGTCT
TTCGCCGATGCCACCATCGC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNIRLVRFAALSGYVDVARASGLDPARMMREHGLDPAGLAQPDRRVAADAVIALLEASADASGVDDFGLRLAERRRLSSL
GPLSLALREQPTVRDVVAMLCRYESMYNESLRIRVVERDGIAAVRLALDAGGAAATQSTDLALAALAGVLRTFLSNTWHP
LRVNLRRPKPSAPAMHHRIFGPRIEFAQQLDEIVVYTSDLDRRNDSFDPLLRQYSQAVLEPPERPGDTTTTDRVRDLIEV
LLPLGRCSVEQVAQGLGVDRRTVHRQLASEGTSFSALLDTIRLDLADHLVTSDRHSLTEISEMLAFSSPSNFSRWFRGHR
AMSPRTWRNLRADAIAAHS

Sequences:

>Translated_339_residues
MNIRLVRFAALSGYVDVARASGLDPARMMREHGLDPAGLAQPDRRVAADAVIALLEASADASGVDDFGLRLAERRRLSSL
GPLSLALREQPTVRDVVAMLCRYESMYNESLRIRVVERDGIAAVRLALDAGGAAATQSTDLALAALAGVLRTFLSNTWHP
LRVNLRRPKPSAPAMHHRIFGPRIEFAQQLDEIVVYTSDLDRRNDSFDPLLRQYSQAVLEPPERPGDTTTTDRVRDLIEV
LLPLGRCSVEQVAQGLGVDRRTVHRQLASEGTSFSALLDTIRLDLADHLVTSDRHSLTEISEMLAFSSPSNFSRWFRGHR
AMSPRTWRNLRADAIAAHS
>Mature_339_residues
MNIRLVRFAALSGYVDVARASGLDPARMMREHGLDPAGLAQPDRRVAADAVIALLEASADASGVDDFGLRLAERRRLSSL
GPLSLALREQPTVRDVVAMLCRYESMYNESLRIRVVERDGIAAVRLALDAGGAAATQSTDLALAALAGVLRTFLSNTWHP
LRVNLRRPKPSAPAMHHRIFGPRIEFAQQLDEIVVYTSDLDRRNDSFDPLLRQYSQAVLEPPERPGDTTTTDRVRDLIEV
LLPLGRCSVEQVAQGLGVDRRTVHRQLASEGTSFSALLDTIRLDLADHLVTSDRHSLTEISEMLAFSSPSNFSRWFRGHR
AMSPRTWRNLRADAIAAHS

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37503; Mature: 37503

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRLVRFAALSGYVDVARASGLDPARMMREHGLDPAGLAQPDRRVAADAVIALLEASAD
CCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
ASGVDDFGLRLAERRRLSSLGPLSLALREQPTVRDVVAMLCRYESMYNESLRIRVVERDG
CCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCC
IAAVRLALDAGGAAATQSTDLALAALAGVLRTFLSNTWHPLRVNLRRPKPSAPAMHHRIF
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHC
GPRIEFAQQLDEIVVYTSDLDRRNDSFDPLLRQYSQAVLEPPERPGDTTTTDRVRDLIEV
CCHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LLPLGRCSVEQVAQGLGVDRRTVHRQLASEGTSFSALLDTIRLDLADHLVTSDRHSLTEI
HHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SEMLAFSSPSNFSRWFRGHRAMSPRTWRNLRADAIAAHS
HHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIRLVRFAALSGYVDVARASGLDPARMMREHGLDPAGLAQPDRRVAADAVIALLEASAD
CCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
ASGVDDFGLRLAERRRLSSLGPLSLALREQPTVRDVVAMLCRYESMYNESLRIRVVERDG
CCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCC
IAAVRLALDAGGAAATQSTDLALAALAGVLRTFLSNTWHPLRVNLRRPKPSAPAMHHRIF
CEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHC
GPRIEFAQQLDEIVVYTSDLDRRNDSFDPLLRQYSQAVLEPPERPGDTTTTDRVRDLIEV
CCHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LLPLGRCSVEQVAQGLGVDRRTVHRQLASEGTSFSALLDTIRLDLADHLVTSDRHSLTEI
HHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SEMLAFSSPSNFSRWFRGHRAMSPRTWRNLRADAIAAHS
HHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]