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The map label for this gene is yhdG [H]

Identifier: 169630679

GI number: 169630679

Start: 3649208

End: 3650683

Strand: Reverse

Name: yhdG [H]

Synonym: MAB_3599c

Alternate gene names: 169630679

Gene position: 3650683-3649208 (Counterclockwise)

Preceding gene: 169630680

Following gene: 169630678

Centisome position: 72.05

GC content: 62.4

Gene sequence:

>1476_bases
ATGCCAGGTAGCGGATTGTGGCGAACCAAGTCTGTCGAACAGTCGATTGCGGATACCGACGAGCCGGAGACCAAGCTTCG
TAGGGACCTAACGTGGTGGGATCTCACCGTTTTCGGGGTCTCGGTGGTTATCGGGGCGGGTATCTTCACCGTCACGGCGT
CGACGGCGGCCAACGTCACCGGGCCGGCGATCTCACTCTCCTTCATCATGGCTGCGATCGGATGCGGGCTGGCGGCGATG
TGCTACGCGGAATTCGCCTCCACCATCCCGGTTGCCGGGAGTGCCTACACCTTTTCCTATGCGACGTTCGGCGAGTTCGC
CGCCTGGATCCTGGGCTGGGATCTGATTCTGGAGTTCTCGGTCGGTGCGGCCACCGTCGCCAAGGGCTGGTCCAGTTATC
TGAGTACGGTATTTGGGTTATCCAGTGGCGCAGTACATCTCGGAGCGGTCAAGATCGACTGGGGTGCATTGCTCATTGTG
TCGGTGCTGACCGTGCTGCTCGCGGTCGGTACCAAGCTGTCCTCGCGGGTATCCCTTGTCATCACCACCATCAAGGTGCT
GGTGGTGCTGCTGGTCATCATTGTCGGTGCGTTCTTCATCAAGACGGCCAACTACACACCGTTCATCCCTCCGGCGGAGG
CGGGCAGTTCCAGTAGGCAGGGACTAGACCAGTCCCTGTTCTCTTTCGTCGCGGGCGGCTCGGGAAGTCAGTACGGCTGG
TTCGGTGTGCTCGCGGGTGCGTCGATCGTTTTCTTCGCGTTCATCGGTTTCGATGTCGTCGCCACGACCGCGGAGGAGAC
GCGGAACCCGCAGAAGGATGTGCCGCGCGGCATCATCGCTTCGTTGGTCATCGTGACCGTCCTGTACGTCGCGGTGACTG
TGGTGCTCTCGGGCATGGTCAAGTACAGCGATCTGCGGGTCGCTGACTCCCATCCGAATCTGTCCACGGCATTCCACCTC
AACGGTGTCGACTGGGCCGCCAAGGTGATCGCGGTCGGTGCATTGGCGGGGCTGACCACCGTGGTCATGGTGCTGATGCT
CGGGCAGATCCGCGTTATTTTCGCGATGTGCCGCGACGGGCTGCTGCCGCGTGAGCTGGCGCGAACCGGCTCGCACGGCA
CACCGATACGGATCACGCTGATCGTTGGCTTTCTTGTTGCGGTAGCCGCTTCTCTCACCCCGATCGAGGGGCTGGAGGAG
ATTGTCAACGTCGGCACGTTGTTCGCGTTTGTGCTGGTGTCGGCCGGCGTCATCGTGCTGCGGCGCTCCCGGCCCGACCT
GCCCCGCAGCTTCCGTACGCCCGGCGTGCCGTGGCTACCGATTGTGGCGATCGTGGCGTGCGGGTGGTTGATGCTCAATC
TCGCGGTGCGGACCTGGTTGTTCGCCTTGAGCTGGATGGTCATCGGCGTGATCGTGTACTTCGCCTACAGCCGCAAGCAC
TCGGTGCTTGGGCTGCGCGTCGACGTCGAGCAGTAA

Upstream 100 bases:

>100_bases
TGATCTATCTGGAACCCGATCTGGATCGTTCGGCGGCAAATTCTTAGCTAGCCGGTGTGATCAACCGTCGTGAGCATGGG
GGTTGTGCGAGACTGCCGTA

Downstream 100 bases:

>100_bases
CCCGGTTTTCCCCGCAGGACCTGCGGGGGTGACGCGCGCCACCAGGCACTTTACAAATCATACTGATTTGTCTAGACACG
CGACGAAACATGCCTTATCG

Product: putative amino acid permease

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MPGSGLWRTKSVEQSIADTDEPETKLRRDLTWWDLTVFGVSVVIGAGIFTVTASTAANVTGPAISLSFIMAAIGCGLAAM
CYAEFASTIPVAGSAYTFSYATFGEFAAWILGWDLILEFSVGAATVAKGWSSYLSTVFGLSSGAVHLGAVKIDWGALLIV
SVLTVLLAVGTKLSSRVSLVITTIKVLVVLLVIIVGAFFIKTANYTPFIPPAEAGSSSRQGLDQSLFSFVAGGSGSQYGW
FGVLAGASIVFFAFIGFDVVATTAEETRNPQKDVPRGIIASLVIVTVLYVAVTVVLSGMVKYSDLRVADSHPNLSTAFHL
NGVDWAAKVIAVGALAGLTTVVMVLMLGQIRVIFAMCRDGLLPRELARTGSHGTPIRITLIVGFLVAVAASLTPIEGLEE
IVNVGTLFAFVLVSAGVIVLRRSRPDLPRSFRTPGVPWLPIVAIVACGWLMLNLAVRTWLFALSWMVIGVIVYFAYSRKH
SVLGLRVDVEQ

Sequences:

>Translated_491_residues
MPGSGLWRTKSVEQSIADTDEPETKLRRDLTWWDLTVFGVSVVIGAGIFTVTASTAANVTGPAISLSFIMAAIGCGLAAM
CYAEFASTIPVAGSAYTFSYATFGEFAAWILGWDLILEFSVGAATVAKGWSSYLSTVFGLSSGAVHLGAVKIDWGALLIV
SVLTVLLAVGTKLSSRVSLVITTIKVLVVLLVIIVGAFFIKTANYTPFIPPAEAGSSSRQGLDQSLFSFVAGGSGSQYGW
FGVLAGASIVFFAFIGFDVVATTAEETRNPQKDVPRGIIASLVIVTVLYVAVTVVLSGMVKYSDLRVADSHPNLSTAFHL
NGVDWAAKVIAVGALAGLTTVVMVLMLGQIRVIFAMCRDGLLPRELARTGSHGTPIRITLIVGFLVAVAASLTPIEGLEE
IVNVGTLFAFVLVSAGVIVLRRSRPDLPRSFRTPGVPWLPIVAIVACGWLMLNLAVRTWLFALSWMVIGVIVYFAYSRKH
SVLGLRVDVEQ
>Mature_490_residues
PGSGLWRTKSVEQSIADTDEPETKLRRDLTWWDLTVFGVSVVIGAGIFTVTASTAANVTGPAISLSFIMAAIGCGLAAMC
YAEFASTIPVAGSAYTFSYATFGEFAAWILGWDLILEFSVGAATVAKGWSSYLSTVFGLSSGAVHLGAVKIDWGALLIVS
VLTVLLAVGTKLSSRVSLVITTIKVLVVLLVIIVGAFFIKTANYTPFIPPAEAGSSSRQGLDQSLFSFVAGGSGSQYGWF
GVLAGASIVFFAFIGFDVVATTAEETRNPQKDVPRGIIASLVIVTVLYVAVTVVLSGMVKYSDLRVADSHPNLSTAFHLN
GVDWAAKVIAVGALAGLTTVVMVLMLGQIRVIFAMCRDGLLPRELARTGSHGTPIRITLIVGFLVAVAASLTPIEGLEEI
VNVGTLFAFVLVSAGVIVLRRSRPDLPRSFRTPGVPWLPIVAIVACGWLMLNLAVRTWLFALSWMVIGVIVYFAYSRKHS
VLGLRVDVEQ

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of D-Alanine, D-Serine And Glycine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=423, Percent_Identity=36.1702127659575, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI4507047, Length=433, Percent_Identity=36.9515011547344, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI258614003, Length=424, Percent_Identity=36.0849056603774, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI258614005, Length=449, Percent_Identity=35.6347438752784, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI114326544, Length=436, Percent_Identity=35.0917431192661, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI114326550, Length=436, Percent_Identity=35.0917431192661, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI181337167, Length=439, Percent_Identity=36.6742596810934, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI110347453, Length=430, Percent_Identity=33.953488372093, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI186910308, Length=446, Percent_Identity=23.542600896861, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI186910306, Length=446, Percent_Identity=23.542600896861, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI186910304, Length=446, Percent_Identity=23.542600896861, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI187423910, Length=494, Percent_Identity=22.0647773279352, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7657591, Length=494, Percent_Identity=22.0647773279352, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI115648063, Length=447, Percent_Identity=23.489932885906, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI115648022, Length=447, Percent_Identity=23.489932885906, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI33286428, Length=405, Percent_Identity=25.1851851851852, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI7657683, Length=370, Percent_Identity=21.8918918918919, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1790653, Length=453, Percent_Identity=24.7240618101545, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786302, Length=372, Percent_Identity=22.3118279569892, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786789, Length=382, Percent_Identity=22.5130890052356, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081869, Length=462, Percent_Identity=23.1601731601732, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786602, Length=427, Percent_Identity=22.248243559719, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI2367353, Length=457, Percent_Identity=22.9759299781182, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788480, Length=454, Percent_Identity=23.7885462555066, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081708, Length=441, Percent_Identity=19.9546485260771, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786694, Length=350, Percent_Identity=22.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082023, Length=240, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789017, Length=460, Percent_Identity=22.1739130434783, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI87081915, Length=409, Percent_Identity=22.4938875305623, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=416, Percent_Identity=36.7788461538462, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17531343, Length=436, Percent_Identity=32.1100917431193, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17533459, Length=432, Percent_Identity=32.6388888888889, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI193208714, Length=431, Percent_Identity=23.6658932714617, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32566695, Length=431, Percent_Identity=23.6658932714617, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537453, Length=352, Percent_Identity=24.1477272727273, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71993915, Length=432, Percent_Identity=22.6851851851852, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17568033, Length=450, Percent_Identity=20.2222222222222, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=246, Percent_Identity=23.1707317073171, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=455, Percent_Identity=22.6373626373626, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71995382, Length=431, Percent_Identity=22.5058004640371, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI221512776, Length=436, Percent_Identity=35.0917431192661, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24666159, Length=436, Percent_Identity=35.0917431192661, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24668806, Length=445, Percent_Identity=31.9101123595506, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI21356285, Length=445, Percent_Identity=31.9101123595506, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24668802, Length=445, Percent_Identity=31.9101123595506, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24667468, Length=445, Percent_Identity=34.6067415730337, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI161077963, Length=445, Percent_Identity=33.7078651685393, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI281366235, Length=430, Percent_Identity=33.4883720930233, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI116007820, Length=430, Percent_Identity=33.4883720930233, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI116007818, Length=426, Percent_Identity=33.5680751173709, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI85725152, Length=426, Percent_Identity=33.5680751173709, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI21357367, Length=457, Percent_Identity=21.2253829321663, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45550968, Length=482, Percent_Identity=25.5186721991701, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19921172, Length=482, Percent_Identity=25.5186721991701, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221331183, Length=461, Percent_Identity=23.644251626898, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647653, Length=461, Percent_Identity=23.644251626898, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664379, Length=461, Percent_Identity=23.644251626898, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651635, Length=435, Percent_Identity=24.367816091954, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651633, Length=435, Percent_Identity=24.367816091954, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52092; Mature: 51961

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGSGLWRTKSVEQSIADTDEPETKLRRDLTWWDLTVFGVSVVIGAGIFTVTASTAANVT
CCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCHHHEEECCCCCCCC
GPAISLSFIMAAIGCGLAAMCYAEFASTIPVAGSAYTFSYATFGEFAAWILGWDLILEFS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
VGAATVAKGWSSYLSTVFGLSSGAVHLGAVKIDWGALLIVSVLTVLLAVGTKLSSRVSLV
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHH
ITTIKVLVVLLVIIVGAFFIKTANYTPFIPPAEAGSSSRQGLDQSLFSFVAGGSGSQYGW
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCCCHH
FGVLAGASIVFFAFIGFDVVATTAEETRNPQKDVPRGIIASLVIVTVLYVAVTVVLSGMV
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
KYSDLRVADSHPNLSTAFHLNGVDWAAKVIAVGALAGLTTVVMVLMLGQIRVIFAMCRDG
HHCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLPRELARTGSHGTPIRITLIVGFLVAVAASLTPIEGLEEIVNVGTLFAFVLVSAGVIVL
CCHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE
RRSRPDLPRSFRTPGVPWLPIVAIVACGWLMLNLAVRTWLFALSWMVIGVIVYFAYSRKH
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVLGLRVDVEQ
CEEEEEEECCC
>Mature Secondary Structure 
PGSGLWRTKSVEQSIADTDEPETKLRRDLTWWDLTVFGVSVVIGAGIFTVTASTAANVT
CCCCCCCCHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCHHHEEECCCCCCCC
GPAISLSFIMAAIGCGLAAMCYAEFASTIPVAGSAYTFSYATFGEFAAWILGWDLILEFS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
VGAATVAKGWSSYLSTVFGLSSGAVHLGAVKIDWGALLIVSVLTVLLAVGTKLSSRVSLV
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHH
ITTIKVLVVLLVIIVGAFFIKTANYTPFIPPAEAGSSSRQGLDQSLFSFVAGGSGSQYGW
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCCCHH
FGVLAGASIVFFAFIGFDVVATTAEETRNPQKDVPRGIIASLVIVTVLYVAVTVVLSGMV
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
KYSDLRVADSHPNLSTAFHLNGVDWAAKVIAVGALAGLTTVVMVLMLGQIRVIFAMCRDG
HHCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLPRELARTGSHGTPIRITLIVGFLVAVAASLTPIEGLEEIVNVGTLFAFVLVSAGVIVL
CCHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEE
RRSRPDLPRSFRTPGVPWLPIVAIVACGWLMLNLAVRTWLFALSWMVIGVIVYFAYSRKH
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVLGLRVDVEQ
CEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]