| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is secA1 [H]
Identifier: 169630660
GI number: 169630660
Start: 3627862
End: 3630651
Strand: Reverse
Name: secA1 [H]
Synonym: MAB_3580c
Alternate gene names: 169630660
Gene position: 3630651-3627862 (Counterclockwise)
Preceding gene: 169630661
Following gene: 169630659
Centisome position: 71.65
GC content: 63.26
Gene sequence:
>2790_bases GTGCTGTCGAAGTTGCTGCGCCTCGGTGAAGGTCGCATGGTCAAGCGTCTCAAGGGCGTGGCCGATTACGTCAACACCCT GTCCGACGACATCGAGAAGCTCTCCGATGCCGAGCTGCAGGCCAAGACCGGCGAGTTCAAGGGGCGCCTGGAGAAGGGCG AGACCCTTGATGACCTGATGCCCGAGGCATTCGCGGTCGCGCGGGAGGCATCCTGGCGCGTGCTGAGCCAGCGGCACTTC GATGTGCAGGTGATGGGTGGCGCCGCGCTGCACGCAGGAAACATCGCCGAGATGAAGACCGGTGAAGGCAAGACCCTGAC CTGTGTGCTGCCCGCATATCTGAACGCGCTGGCCGGTAAGGGCACCCACGTCGTCACCGTCAACGACTACCTGGCCAAGC GTGACTCGGAGTGGATGGGCCGCGTACACCGCTTCCTAGGGCTGGATGTGGGCGTGATCCTGTCGCAGATGACCCCGTTG GAGCGTCGCGACGCGTACAACGCCGACATCACCTACGGCACCAACAATGAGTTCGGCTTCGACTATCTGCGCGACAACAT GACCCATTCGCTCGACGAGCTGGTGCAACGTGGACATGCCTTCGCCATCGTCGACGAGGTCGACTCGATCCTCATCGACG AGGCCCGAACCCCGCTGATCATCTCGGGCCCGGCCGATGGCGCGTCCAATTGGTACACCGAGTTCGCACGGATCGTCCCC CTGATGGAGAAGGACACCCACTACGAGGTGGACATCCGCAAGCGCACTATCGGGGTGCACGAGCTGGGCGTGGAGTTCGT CGAAGACCAGCTGGGCATCGACAATCTGTACGAGGCGGCCAACTCGCCGCTGGTGAGCTACCTGAACAACGCCATCAAGG CCAAGGAACTGTTCACCCGCGACAAGGACTACATCGTGCGCGAGGGTGAGGTGCTGATCGTCGACGAGTTCACCGGCCGT GTGCTGATGGGGCGTCGTTACAACGAGGGCATGCACCAGGCCATCGAGGCCAAGGAGCGGGTGGAGATCAAGGCCGAGAA CCAGACGCTGGCCACCATCACCCTGCAGAACTACTTCCGTCTCTACGACAAGCTCGCCGGCATGACCGGTACTGCCCAGA CCGAGGCGGCCGAGCTCAACGAGATCTACAAGCTCGGTGTGGTGTCCATCCCCACCAACAGGCCGATGGTGCGCAAGGAC CAGTCCGACCTCATCTACAAGACCGAGGAAGCCAAGTACATCGCCGTTGTCGACGATGTGGTGGAGCGGTACGAGAAGGG ACAGCCCGTCCTCATCGGTACCACGAGTGTTGAACGCTCCGAATACCTTTCGCGACAGTTCACCAAGCGTCGCGTTCCGC ACAATGTGCTCAACGCCAAGTACCACGAACAAGAAGCCGCCATCATCGCGGAGGCCGGGCGCCGCGGCGCCATCACGGTG GCCACCAACATGGCCGGCCGTGGTACCGACATCGTGCTGGGCGGTAACCCGGACTTTCTGGCGGACAAGCACCTTCGCGA GCAAGGCCTGGACCCGGTGGAGACTCCGGACGAATACCAGGCCGCCTGGGACGAGACGCTGCAGAAGTTCAAGGACGCTG CCGAAACCGAGGCCAAGGAGGTGCAGGAGGCCGGTGGACTATACGTGCTGGGCACCGAACGGCACGAATCACGGCGTATC GACAACCAGCTGCGTGGGCGCTCCGGGCGTCAGGGCGACCCGGGCGAGTCCCGCTTCTATCTGTCGCTGCAGGATGAACT GATGCGCCGCTTCAATGGTGCTGCGCTGGAAACGATCCTGACGCGCATGAACGTCCCGGACGACGTGCCGATCGAGGCCA AGATGGTGACCAATGCCATCAAGAGTGCGCAAACTCAGGTTGAGCAGCAGAACTTCGAGGTCCGAAAGAACGTCCTCAAG TACGACGAGGTGATGAACCAACAGCGCAAGGTCATCTATGCCGAGCGTCGCCGGATCCTCGACGGGGAGGATCTGCAGCC GCAGATCCAGGAGATGATCACCGACACCATCGCCGCCTACGTCGATGGCGCCACCGCCGATGGCTACCACGAGGACTGGG ACTTCGACGCGCTCTGGACCGCGCTCAAGACGCTGTACCCGGTAAGCCTCAAGCCCGAAGAGCTGATCGCCTCCGGCGAG TACGGTGAGGCCGACGAACTGAGCCCCGAGGATCTCAAGGCTGCCCTGCTCGAGGACGCGAAGAAGGCTTATAAGGCAAG GGAAGCCGAGATCGACGGGCTGGCGGGTGAGGGCTCTATGCGCCAACTGGAGCGCAACATTCTGCTCAGTGTGATCGACC GCAAATGGCGTGAGCACCTCTACGAGATGGACTACCTCAAGGAGGGCATCGGCCTGCGTGCCATGGCGCAGCGCGACCCG CTGGTCGAGTACCAGCGCGAGGGCTACGACATGTTCACCGCGATGCTTGACGGCCTCAAGGAAGAGTCGGTGGGCTTCCT GTTCAATATCAACGTCGAGGTCCAGCAGCCGGACGGCGCCGCCGTCGCCCCTCAGGAAGCACCCGAGGGTCTGGCTGAAT TCGCTTCTGCCGCAGCTCAAGCCGCGCACGGGGAGCTGCGGGCCAAGGGGCTTGAAGAGTCCACTCCGGAGCTGACGTAT TCGGGTCCTGCCGAGGACGGTTCGGCGCAGTCCCGACACGAAAACGGCGCAGCCTCGGCGTCGGGTGGTGGCACGCGCCG TGAGCGCCGGGAAGCGGCACGCAACGCGGGACGCACCTCCAAGCCGGCGAAGTCGCGCCGCAAGCGCTAG
Upstream 100 bases:
>100_bases ATTCCGCGCAGGGCAGACATTGGACGGCGCCGCCGGGGGCGACGCCTACGATGGGACTCGCTGAATCTGACAAGTCCTAA CGAGTACAGGGGATATTGAC
Downstream 100 bases:
>100_bases CCGTCGACACCTACCGGACATCCCGAGGTGCGGGATGCCCGGTAGGCGCTCGTCACGGGGGTCTCTCGATACTCCGCAAC GCTGCGACAGTCGGATGGCC
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 929; Mature: 929
Protein sequence:
>929_residues MLSKLLRLGEGRMVKRLKGVADYVNTLSDDIEKLSDAELQAKTGEFKGRLEKGETLDDLMPEAFAVAREASWRVLSQRHF DVQVMGGAALHAGNIAEMKTGEGKTLTCVLPAYLNALAGKGTHVVTVNDYLAKRDSEWMGRVHRFLGLDVGVILSQMTPL ERRDAYNADITYGTNNEFGFDYLRDNMTHSLDELVQRGHAFAIVDEVDSILIDEARTPLIISGPADGASNWYTEFARIVP LMEKDTHYEVDIRKRTIGVHELGVEFVEDQLGIDNLYEAANSPLVSYLNNAIKAKELFTRDKDYIVREGEVLIVDEFTGR VLMGRRYNEGMHQAIEAKERVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELNEIYKLGVVSIPTNRPMVRKD QSDLIYKTEEAKYIAVVDDVVERYEKGQPVLIGTTSVERSEYLSRQFTKRRVPHNVLNAKYHEQEAAIIAEAGRRGAITV ATNMAGRGTDIVLGGNPDFLADKHLREQGLDPVETPDEYQAAWDETLQKFKDAAETEAKEVQEAGGLYVLGTERHESRRI DNQLRGRSGRQGDPGESRFYLSLQDELMRRFNGAALETILTRMNVPDDVPIEAKMVTNAIKSAQTQVEQQNFEVRKNVLK YDEVMNQQRKVIYAERRRILDGEDLQPQIQEMITDTIAAYVDGATADGYHEDWDFDALWTALKTLYPVSLKPEELIASGE YGEADELSPEDLKAALLEDAKKAYKAREAEIDGLAGEGSMRQLERNILLSVIDRKWREHLYEMDYLKEGIGLRAMAQRDP LVEYQREGYDMFTAMLDGLKEESVGFLFNINVEVQQPDGAAVAPQEAPEGLAEFASAAAQAAHGELRAKGLEESTPELTY SGPAEDGSAQSRHENGAASASGGGTRRERREAARNAGRTSKPAKSRRKR
Sequences:
>Translated_929_residues MLSKLLRLGEGRMVKRLKGVADYVNTLSDDIEKLSDAELQAKTGEFKGRLEKGETLDDLMPEAFAVAREASWRVLSQRHF DVQVMGGAALHAGNIAEMKTGEGKTLTCVLPAYLNALAGKGTHVVTVNDYLAKRDSEWMGRVHRFLGLDVGVILSQMTPL ERRDAYNADITYGTNNEFGFDYLRDNMTHSLDELVQRGHAFAIVDEVDSILIDEARTPLIISGPADGASNWYTEFARIVP LMEKDTHYEVDIRKRTIGVHELGVEFVEDQLGIDNLYEAANSPLVSYLNNAIKAKELFTRDKDYIVREGEVLIVDEFTGR VLMGRRYNEGMHQAIEAKERVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELNEIYKLGVVSIPTNRPMVRKD QSDLIYKTEEAKYIAVVDDVVERYEKGQPVLIGTTSVERSEYLSRQFTKRRVPHNVLNAKYHEQEAAIIAEAGRRGAITV ATNMAGRGTDIVLGGNPDFLADKHLREQGLDPVETPDEYQAAWDETLQKFKDAAETEAKEVQEAGGLYVLGTERHESRRI DNQLRGRSGRQGDPGESRFYLSLQDELMRRFNGAALETILTRMNVPDDVPIEAKMVTNAIKSAQTQVEQQNFEVRKNVLK YDEVMNQQRKVIYAERRRILDGEDLQPQIQEMITDTIAAYVDGATADGYHEDWDFDALWTALKTLYPVSLKPEELIASGE YGEADELSPEDLKAALLEDAKKAYKAREAEIDGLAGEGSMRQLERNILLSVIDRKWREHLYEMDYLKEGIGLRAMAQRDP LVEYQREGYDMFTAMLDGLKEESVGFLFNINVEVQQPDGAAVAPQEAPEGLAEFASAAAQAAHGELRAKGLEESTPELTY SGPAEDGSAQSRHENGAASASGGGTRRERREAARNAGRTSKPAKSRRKR >Mature_929_residues MLSKLLRLGEGRMVKRLKGVADYVNTLSDDIEKLSDAELQAKTGEFKGRLEKGETLDDLMPEAFAVAREASWRVLSQRHF DVQVMGGAALHAGNIAEMKTGEGKTLTCVLPAYLNALAGKGTHVVTVNDYLAKRDSEWMGRVHRFLGLDVGVILSQMTPL ERRDAYNADITYGTNNEFGFDYLRDNMTHSLDELVQRGHAFAIVDEVDSILIDEARTPLIISGPADGASNWYTEFARIVP LMEKDTHYEVDIRKRTIGVHELGVEFVEDQLGIDNLYEAANSPLVSYLNNAIKAKELFTRDKDYIVREGEVLIVDEFTGR VLMGRRYNEGMHQAIEAKERVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELNEIYKLGVVSIPTNRPMVRKD QSDLIYKTEEAKYIAVVDDVVERYEKGQPVLIGTTSVERSEYLSRQFTKRRVPHNVLNAKYHEQEAAIIAEAGRRGAITV ATNMAGRGTDIVLGGNPDFLADKHLREQGLDPVETPDEYQAAWDETLQKFKDAAETEAKEVQEAGGLYVLGTERHESRRI DNQLRGRSGRQGDPGESRFYLSLQDELMRRFNGAALETILTRMNVPDDVPIEAKMVTNAIKSAQTQVEQQNFEVRKNVLK YDEVMNQQRKVIYAERRRILDGEDLQPQIQEMITDTIAAYVDGATADGYHEDWDFDALWTALKTLYPVSLKPEELIASGE YGEADELSPEDLKAALLEDAKKAYKAREAEIDGLAGEGSMRQLERNILLSVIDRKWREHLYEMDYLKEGIGLRAMAQRDP LVEYQREGYDMFTAMLDGLKEESVGFLFNINVEVQQPDGAAVAPQEAPEGLAEFASAAAQAAHGELRAKGLEESTPELTY SGPAEDGSAQSRHENGAASASGGGTRRERREAARNAGRTSKPAKSRRKR
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=851, Percent_Identity=49.3537015276146, Blast_Score=796, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 103984; Mature: 103984
Theoretical pI: Translated: 4.79; Mature: 4.79
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLSKLLRLGEGRMVKRLKGVADYVNTLSDDIEKLSDAELQAKTGEFKGRLEKGETLDDLM CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCCCCCCHHHHH PEAFAVAREASWRVLSQRHFDVQVMGGAALHAGNIAEMKTGEGKTLTCVLPAYLNALAGK HHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCCHHCCCCCCCEEEEEHHHHHHHHCCC GTHVVTVNDYLAKRDSEWMGRVHRFLGLDVGVILSQMTPLERRDAYNADITYGTNNEFGF CCEEEEECHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCCEEEECCCCCCCH DYLRDNMTHSLDELVQRGHAFAIVDEVDSILIDEARTPLIISGPADGASNWYTEFARIVP HHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH LMEKDTHYEVDIRKRTIGVHELGVEFVEDQLGIDNLYEAANSPLVSYLNNAIKAKELFTR HHCCCCCEEEEEHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHC DKDYIVREGEVLIVDEFTGRVLMGRRYNEGMHQAIEAKERVEIKAENQTLATITLQNYFR CCCCEEECCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHEEEEECCCEEEEEEHHHHHH LYDKLAGMTGTAQTEAAELNEIYKLGVVSIPTNRPMVRKDQSDLIYKTEEAKYIAVVDDV HHHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEECCCCEEHHHHHH VERYEKGQPVLIGTTSVERSEYLSRQFTKRRVPHNVLNAKYHEQEAAIIAEAGRRGAITV HHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCCEEEE ATNMAGRGTDIVLGGNPDFLADKHLREQGLDPVETPDEYQAAWDETLQKFKDAAETEAKE EECCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH VQEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLQDELMRRFNGAALETIL HHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHH TRMNVPDDVPIEAKMVTNAIKSAQTQVEQQNFEVRKNVLKYDEVMNQQRKVIYAERRRIL HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC DGEDLQPQIQEMITDTIAAYVDGATADGYHEDWDFDALWTALKTLYPVSLKPEELIASGE CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCC YGEADELSPEDLKAALLEDAKKAYKAREAEIDGLAGEGSMRQLERNILLSVIDRKWREHL CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH YEMDYLKEGIGLRAMAQRDPLVEYQREGYDMFTAMLDGLKEESVGFLFNINVEVQQPDGA HHHHHHHHCCCCEEHHHCCCHHHHHHCCHHHHHHHHHCCHHCCCCEEEEEEEEEECCCCC AVAPQEAPEGLAEFASAAAQAAHGELRAKGLEESTPELTYSGPAEDGSAQSRHENGAASA CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHCCCCCCCC SGGGTRRERREAARNAGRTSKPAKSRRKR CCCCCHHHHHHHHHHCCCCCCCHHHHCCC >Mature Secondary Structure MLSKLLRLGEGRMVKRLKGVADYVNTLSDDIEKLSDAELQAKTGEFKGRLEKGETLDDLM CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCCCCCCHHHHH PEAFAVAREASWRVLSQRHFDVQVMGGAALHAGNIAEMKTGEGKTLTCVLPAYLNALAGK HHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCCHHCCCCCCCEEEEEHHHHHHHHCCC GTHVVTVNDYLAKRDSEWMGRVHRFLGLDVGVILSQMTPLERRDAYNADITYGTNNEFGF CCEEEEECHHHHHCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCCEEEECCCCCCCH DYLRDNMTHSLDELVQRGHAFAIVDEVDSILIDEARTPLIISGPADGASNWYTEFARIVP HHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHH LMEKDTHYEVDIRKRTIGVHELGVEFVEDQLGIDNLYEAANSPLVSYLNNAIKAKELFTR HHCCCCCEEEEEHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHC DKDYIVREGEVLIVDEFTGRVLMGRRYNEGMHQAIEAKERVEIKAENQTLATITLQNYFR CCCCEEECCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHEEEEECCCEEEEEEHHHHHH LYDKLAGMTGTAQTEAAELNEIYKLGVVSIPTNRPMVRKDQSDLIYKTEEAKYIAVVDDV HHHHHCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEECCCCEEHHHHHH VERYEKGQPVLIGTTSVERSEYLSRQFTKRRVPHNVLNAKYHEQEAAIIAEAGRRGAITV HHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHCCCCCEEEE ATNMAGRGTDIVLGGNPDFLADKHLREQGLDPVETPDEYQAAWDETLQKFKDAAETEAKE EECCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH VQEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLQDELMRRFNGAALETIL HHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHH TRMNVPDDVPIEAKMVTNAIKSAQTQVEQQNFEVRKNVLKYDEVMNQQRKVIYAERRRIL HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC DGEDLQPQIQEMITDTIAAYVDGATADGYHEDWDFDALWTALKTLYPVSLKPEELIASGE CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCC YGEADELSPEDLKAALLEDAKKAYKAREAEIDGLAGEGSMRQLERNILLSVIDRKWREHL CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH YEMDYLKEGIGLRAMAQRDPLVEYQREGYDMFTAMLDGLKEESVGFLFNINVEVQQPDGA HHHHHHHHCCCCEEHHHCCCHHHHHHCCHHHHHHHHHCCHHCCCCEEEEEEEEEECCCCC AVAPQEAPEGLAEFASAAAQAAHGELRAKGLEESTPELTYSGPAEDGSAQSRHENGAASA CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCHHHCCCCCCCC SGGGTRRERREAARNAGRTSKPAKSRRKR CCCCCHHHHHHHHHHCCCCCCCHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11717254 [H]