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The map label for this gene is moeZ [H]

Identifier: 169630606

GI number: 169630606

Start: 3572233

End: 3573408

Strand: Reverse

Name: moeZ [H]

Synonym: MAB_3525c

Alternate gene names: 169630606

Gene position: 3573408-3572233 (Counterclockwise)

Preceding gene: 169630607

Following gene: 169630605

Centisome position: 70.52

GC content: 64.37

Gene sequence:

>1176_bases
GTGCCCACATTGCCGCCGTTGGTACGTCCCGCCGCGGAACTGACCCGCGAAGAAGTCGCCCGGTACAGCCGGCATCTGAT
CATTCCCGACCTGGGTGTGGACGGGCAGAAACGCCTCAAGAACGCCAAGGTGCTCGTCATCGGCGCCGGCGGGCTGGGAT
CCCCGACGCTGCTGTACCTGGCCGCTGCGGGTGTCGGCACCATCGGCATCGTCGAGTTCGATGTGGTCGACGAGTCCAAC
CTGCAGCGCCAGATCATCCACGGCCAGTCCGATATCGGCAGGTCCAAGGCACAGAGCGCGCGCGATTCGGTGTTGGAGAT
CAACCCGCTGGTCGAGGTGCGGCTGCATGAGTTGCGTCTGGATCCGGAAAATGCGGTCGAGCTCTTTGCGCAGTACGACC
TGATCCTGGACGGTACCGACAACTTCGCGACGCGTTACCTGGTCAACGATGCCGCGGTGCTTGCGCACAAGCCCTATGTG
TGGGGCTCCATCTACCGCTTCGAGGGGCAGGTCTCGGTCTTTTGGGAGGACGCCCCGGACGGGCTCGGCCTGAACTACCG
CGATCTGTACCCCGAGCCGCCGCCGCCGGGCATGGTGCCCTCCTGCGCCGAGGGTGGGGTTCTGGGCATCCTGTGCGCCT
CCATCGCCTCGGTGATGGGTACCGAGGCGATCAAGCTGATCACCGGCATCGGTGACTCGCTGCTGGGCCGCCTCATGGTG
TACGACGCACTCGACATGACCTACCGCACCATAAAGATCCGCAAGGATCCGGCCACGCCCAAGATCACCGAGCTCATCGA
CTATGAGGCATTCTGCGGTGTGATCAGCGACGAGGCCTCGGCCGCTGTCGCCGATTCCACCATCACGCCGCGTGAGCTGC
GTGAGCTGCTCGACACCGACAAGAAGGTGGCACTGATCGACGTACGTGAGCCGGTCGAATGGGACATCGTCCACATCGAC
GGTGCCGAGCTGGTGCCCAAGTCGACCCTTGAGTCCGGAGACGGCCTGGCCAAGCTGCCACAGGACCGGCAGGCGGTGCT
GTATTGCAAGACGGGTATTCGGTCGGCAGAGGCGCTCGTGGCCGTGAAAAAGGCGGGCTTCTCGGATGCGGTGCATCTGC
AGGGCGGTATCGCCGCCTGGGCCAAGCAGGTGGACCCCGACATGGTCATGTACTGA

Upstream 100 bases:

>100_bases
GCCGTACCCGATTCCGTAGCGGTCACTGGTCTGGCTCCGGGAAGGGTTGGCATCCCGATACTGTTGATGCTGCTGTAGCC
CTCAACCATCAGGAGTCACG

Downstream 100 bases:

>100_bases
CCGACTGGGCACCAGCAACAGCCACACGTTACGGACGTGCCACCTGTGACTGCCGACACGAACGGCGAGCGAACACAACC
CAGTTCATTGCAGGCGGTAA

Product: molybdenum cofactor biosynthesis protein MoeB1

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MPTLPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVLVIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESN
LQRQIIHGQSDIGRSKAQSARDSVLEINPLVEVRLHELRLDPENAVELFAQYDLILDGTDNFATRYLVNDAAVLAHKPYV
WGSIYRFEGQVSVFWEDAPDGLGLNYRDLYPEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMV
YDALDMTYRTIKIRKDPATPKITELIDYEAFCGVISDEASAAVADSTITPRELRELLDTDKKVALIDVREPVEWDIVHID
GAELVPKSTLESGDGLAKLPQDRQAVLYCKTGIRSAEALVAVKKAGFSDAVHLQGGIAAWAKQVDPDMVMY

Sequences:

>Translated_391_residues
MPTLPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVLVIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESN
LQRQIIHGQSDIGRSKAQSARDSVLEINPLVEVRLHELRLDPENAVELFAQYDLILDGTDNFATRYLVNDAAVLAHKPYV
WGSIYRFEGQVSVFWEDAPDGLGLNYRDLYPEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMV
YDALDMTYRTIKIRKDPATPKITELIDYEAFCGVISDEASAAVADSTITPRELRELLDTDKKVALIDVREPVEWDIVHID
GAELVPKSTLESGDGLAKLPQDRQAVLYCKTGIRSAEALVAVKKAGFSDAVHLQGGIAAWAKQVDPDMVMY
>Mature_390_residues
PTLPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVLVIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNL
QRQIIHGQSDIGRSKAQSARDSVLEINPLVEVRLHELRLDPENAVELFAQYDLILDGTDNFATRYLVNDAAVLAHKPYVW
GSIYRFEGQVSVFWEDAPDGLGLNYRDLYPEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMVY
DALDMTYRTIKIRKDPATPKITELIDYEAFCGVISDEASAAVADSTITPRELRELLDTDKKVALIDVREPVEWDIVHIDG
AELVPKSTLESGDGLAKLPQDRQAVLYCKTGIRSAEALVAVKKAGFSDAVHLQGGIAAWAKQVDPDMVMY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=414, Percent_Identity=38.8888888888889, Blast_Score=239, Evalue=2e-63,
Organism=Homo sapiens, GI4885649, Length=132, Percent_Identity=37.1212121212121, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI38045944, Length=114, Percent_Identity=36.8421052631579, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI38045942, Length=114, Percent_Identity=36.8421052631579, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1787048, Length=249, Percent_Identity=37.7510040160643, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI87082356, Length=250, Percent_Identity=35.6, Blast_Score=148, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17540406, Length=411, Percent_Identity=36.2530413625304, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI193203301, Length=141, Percent_Identity=32.6241134751773, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71984476, Length=118, Percent_Identity=36.4406779661017, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=407, Percent_Identity=36.6093366093366, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6320598, Length=140, Percent_Identity=32.1428571428571, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6322639, Length=217, Percent_Identity=26.2672811059908, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325438, Length=124, Percent_Identity=28.2258064516129, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582879, Length=404, Percent_Identity=39.8514851485149, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24660640, Length=139, Percent_Identity=35.9712230215827, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573937, Length=191, Percent_Identity=25.6544502617801, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42398; Mature: 42267

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVLVIGAGGLGSPTLLYL
CCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHCCCEEEEEECCCCCCCHHEEE
AAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRSKAQSARDSVLEINPLVEVRLHELRL
ECCCCCEEEEEEEEECCCCCCHHHHHCCCCCCCHHHHHHHHCCEEEECCHHEEEEEHHCC
DPENAVELFAQYDLILDGTDNFATRYLVNDAAVLAHKPYVWGSIYRFEGQVSVFWEDAPD
CHHHHHHHHHHEEEEEECCCCCEEEEEECCCCEEEECCCEEEEEEEECCEEEEEEECCCC
GLGLNYRDLYPEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMV
CCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
YDALDMTYRTIKIRKDPATPKITELIDYEAFCGVISDEASAAVADSTITPRELRELLDTD
HHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHCCC
KKVALIDVREPVEWDIVHIDGAELVPKSTLESGDGLAKLPQDRQAVLYCKTGIRSAEALV
CEEEEEEECCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHH
AVKKAGFSDAVHLQGGIAAWAKQVDPDMVMY
HHHHCCCCCEEEECCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PTLPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVLVIGAGGLGSPTLLYL
CCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHCCCEEEEEECCCCCCCHHEEE
AAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRSKAQSARDSVLEINPLVEVRLHELRL
ECCCCCEEEEEEEEECCCCCCHHHHHCCCCCCCHHHHHHHHCCEEEECCHHEEEEEHHCC
DPENAVELFAQYDLILDGTDNFATRYLVNDAAVLAHKPYVWGSIYRFEGQVSVFWEDAPD
CHHHHHHHHHHEEEEEECCCCCEEEEEECCCCEEEECCCEEEEEEEECCEEEEEEECCCC
GLGLNYRDLYPEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMV
CCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
YDALDMTYRTIKIRKDPATPKITELIDYEAFCGVISDEASAAVADSTITPRELRELLDTD
HHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHCCC
KKVALIDVREPVEWDIVHIDGAELVPKSTLESGDGLAKLPQDRQAVLYCKTGIRSAEALV
CEEEEEEECCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHH
AVKKAGFSDAVHLQGGIAAWAKQVDPDMVMY
HHHHCCCCCEEEECCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]