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The map label for this gene is bcd [H]

Identifier: 169630568

GI number: 169630568

Start: 3528825

End: 3530036

Strand: Direct

Name: bcd [H]

Synonym: MAB_3487

Alternate gene names: 169630568

Gene position: 3528825-3530036 (Clockwise)

Preceding gene: 169630567

Following gene: 169630569

Centisome position: 69.64

GC content: 65.1

Gene sequence:

>1212_bases
ATGGCAATCAATTTGGAACTCCCCAAGAAGTTGCAGGCCATCGTCGAGAAGGGGCATCAGGGCGCTGCGGAGCTGGTGCG
GCCCATCTCTCGCAAGTATGACCTGGCCGAGCACGCCTACCCCGTCGAACTGGAGACCCTGGAGACGCTATTCGCGGGCG
TCACCGCGGCCGGCACCTTCGCCTTCGCCGGCGCCGAGGCCTTCCGCGCCGAAGAGAACACCGCTAAGCAAAACGTCAAC
GGCGCCAACATGTCCGCGCTGCTCAATGCCCTCGAAATGAGCTGGGGCGATGTCGGTCTGCTGCTGACGGTGCCCTACCA
GGGCCTGGGCAACGCCGCCGTATCGAGCGTCACCAGCAAGGAAGACGGTGACCGCTTCGGCAAGATCTGGGCGGCCATGG
CCATCACCGAGCCCGGCTTCGGCTCGGACTCGGCAGCCGTCTCGACCACCGCCAAGCTCGACGGTGACGAGTACGTCATC
AACGGCGAAAAGATCTTCGTCACCGCCGGCTCCCGCGCCACCCACATCGTGGTCTGGGCGACGCTGGACAAGACCAAGGG
CCGCCCCGCCATCAAGTCCTTCCTGGTGCCGCGTGAACACCCTGGCGTGACGATCGAGCGCCTCGAAGAGAAGCTGGGCA
TCAAGGCCTCGGACACCGCCGTCATCCGCTTCGACAACGCCCGGATCCCCAAGGATTACATCCTGTCCGATCCGGAGATC
AACACCGAAAAGGGTTTCGGCGGTGTGATGAGCACCTTCGACAACACCCGCCCGATCGTGGCCGCCATGGCCGTGGGTGT
CTCCCGGGCCTCGCTGGAGGAGCTGCGCAAGATCCTCGAGGACGCAGGCATCGAGATCTCCTATGACCGGCCGGCGCATG
CGCAGCACGCGGCTGCTGCCGAGTTCCTGCGGATGGAGGCCGACTGGGAGTCGTCGTACCTGCTGACGCTGCGTAGCGCA
TGGCAGGCCGACAACAACGTGCCCAACTCGATGGAGGCCTCGATGGCCAAGGCCAAAGCCGGCCGCGTCGGCAGCGACAT
CACCCTCAAGGCCGTCGAGATGGCCGGAACCACCGGCTATTCCGAGCGCACCCTGTTGGAGAAGTGGGGCCGCGACTCCA
AGATCCTGGACATCTTCGAGGGCACCCAGCAGATTCAGCAGCTGGTGGTGGCGCGCCGCCTGCTGGGGCTGAGCTCCGCA
GAACTCAAGTGA

Upstream 100 bases:

>100_bases
GCGCTGGTACCGCAACCTGCGCGCCATCGGTGTCGCCGAAGGCGTCGTTGTCCTGTAGCCATCCACTCCCCGGTCTTATC
TACTAAACGAAAGTCTTTCC

Downstream 100 bases:

>100_bases
CGCACTGATCAAGATCCATTGCGGCCCTTCCGGGGAACTCTCCGGAGGGGCCGCACCCTTTTCGTCGAGCCCATTGAGCA
CGAAGCAACAAATACAGCTA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAINLELPKKLQAIVEKGHQGAAELVRPISRKYDLAEHAYPVELETLETLFAGVTAAGTFAFAGAEAFRAEENTAKQNVN
GANMSALLNALEMSWGDVGLLLTVPYQGLGNAAVSSVTSKEDGDRFGKIWAAMAITEPGFGSDSAAVSTTAKLDGDEYVI
NGEKIFVTAGSRATHIVVWATLDKTKGRPAIKSFLVPREHPGVTIERLEEKLGIKASDTAVIRFDNARIPKDYILSDPEI
NTEKGFGGVMSTFDNTRPIVAAMAVGVSRASLEELRKILEDAGIEISYDRPAHAQHAAAAEFLRMEADWESSYLLTLRSA
WQADNNVPNSMEASMAKAKAGRVGSDITLKAVEMAGTTGYSERTLLEKWGRDSKILDIFEGTQQIQQLVVARRLLGLSSA
ELK

Sequences:

>Translated_403_residues
MAINLELPKKLQAIVEKGHQGAAELVRPISRKYDLAEHAYPVELETLETLFAGVTAAGTFAFAGAEAFRAEENTAKQNVN
GANMSALLNALEMSWGDVGLLLTVPYQGLGNAAVSSVTSKEDGDRFGKIWAAMAITEPGFGSDSAAVSTTAKLDGDEYVI
NGEKIFVTAGSRATHIVVWATLDKTKGRPAIKSFLVPREHPGVTIERLEEKLGIKASDTAVIRFDNARIPKDYILSDPEI
NTEKGFGGVMSTFDNTRPIVAAMAVGVSRASLEELRKILEDAGIEISYDRPAHAQHAAAAEFLRMEADWESSYLLTLRSA
WQADNNVPNSMEASMAKAKAGRVGSDITLKAVEMAGTTGYSERTLLEKWGRDSKILDIFEGTQQIQQLVVARRLLGLSSA
ELK
>Mature_402_residues
AINLELPKKLQAIVEKGHQGAAELVRPISRKYDLAEHAYPVELETLETLFAGVTAAGTFAFAGAEAFRAEENTAKQNVNG
ANMSALLNALEMSWGDVGLLLTVPYQGLGNAAVSSVTSKEDGDRFGKIWAAMAITEPGFGSDSAAVSTTAKLDGDEYVIN
GEKIFVTAGSRATHIVVWATLDKTKGRPAIKSFLVPREHPGVTIERLEEKLGIKASDTAVIRFDNARIPKDYILSDPEIN
TEKGFGGVMSTFDNTRPIVAAMAVGVSRASLEELRKILEDAGIEISYDRPAHAQHAAAAEFLRMEADWESSYLLTLRSAW
QADNNVPNSMEASMAKAKAGRVGSDITLKAVEMAGTTGYSERTLLEKWGRDSKILDIFEGTQQIQQLVVARRLLGLSSAE
LK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=406, Percent_Identity=31.0344827586207, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI187960098, Length=319, Percent_Identity=33.8557993730408, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI4557231, Length=319, Percent_Identity=33.8557993730408, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI4501859, Length=263, Percent_Identity=30.4182509505703, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4501857, Length=278, Percent_Identity=28.0575539568345, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI21361497, Length=292, Percent_Identity=29.4520547945205, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI76496475, Length=410, Percent_Identity=26.0975609756098, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4557235, Length=412, Percent_Identity=25.9708737864078, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI226958412, Length=276, Percent_Identity=26.0869565217391, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI226958414, Length=276, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7656849, Length=332, Percent_Identity=24.0963855421687, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4503943, Length=282, Percent_Identity=23.758865248227, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI87081958, Length=265, Percent_Identity=26.0377358490566, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786223, Length=268, Percent_Identity=24.6268656716418, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=333, Percent_Identity=35.4354354354354, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17570075, Length=318, Percent_Identity=34.2767295597484, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17534899, Length=323, Percent_Identity=33.1269349845201, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17508101, Length=266, Percent_Identity=33.0827067669173, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17506239, Length=267, Percent_Identity=29.9625468164794, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17538396, Length=276, Percent_Identity=28.2608695652174, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=329, Percent_Identity=26.1398176291793, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71990804, Length=210, Percent_Identity=31.9047619047619, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=272, Percent_Identity=27.2058823529412, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=276, Percent_Identity=25.3623188405797, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=150, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=272, Percent_Identity=25.7352941176471, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=211, Percent_Identity=30.3317535545024, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=150, Percent_Identity=28.6666666666667, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=274, Percent_Identity=23.7226277372263, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24660351, Length=325, Percent_Identity=36.3076923076923, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24646207, Length=315, Percent_Identity=31.4285714285714, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356377, Length=293, Percent_Identity=32.7645051194539, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24666513, Length=264, Percent_Identity=31.8181818181818, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281363737, Length=322, Percent_Identity=25.776397515528, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920834, Length=306, Percent_Identity=27.4509803921569, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21355753, Length=276, Percent_Identity=26.4492753623188, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 43531; Mature: 43400

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINLELPKKLQAIVEKGHQGAAELVRPISRKYDLAEHAYPVELETLETLFAGVTAAGTF
CEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHH
AFAGAEAFRAEENTAKQNVNGANMSALLNALEMSWGDVGLLLTVPYQGLGNAAVSSVTSK
HHHCHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCC
EDGDRFGKIWAAMAITEPGFGSDSAAVSTTAKLDGDEYVINGEKIFVTAGSRATHIVVWA
CCCHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCEEEECCCEEEEEECCCCEEEEEEE
TLDKTKGRPAIKSFLVPREHPGVTIERLEEKLGIKASDTAVIRFDNARIPKDYILSDPEI
EECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCCCCC
NTEKGFGGVMSTFDNTRPIVAAMAVGVSRASLEELRKILEDAGIEISYDRPAHAQHAAAA
CCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHH
EFLRMEADWESSYLLTLRSAWQADNNVPNSMEASMAKAKAGRVGSDITLKAVEMAGTTGY
HHHHHCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCC
SERTLLEKWGRDSKILDIFEGTQQIQQLVVARRLLGLSSAELK
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AINLELPKKLQAIVEKGHQGAAELVRPISRKYDLAEHAYPVELETLETLFAGVTAAGTF
EECCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHH
AFAGAEAFRAEENTAKQNVNGANMSALLNALEMSWGDVGLLLTVPYQGLGNAAVSSVTSK
HHHCHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHCC
EDGDRFGKIWAAMAITEPGFGSDSAAVSTTAKLDGDEYVINGEKIFVTAGSRATHIVVWA
CCCHHHHHHHHHEEECCCCCCCCCCCEEEEEEECCCEEEECCCEEEEEECCCCEEEEEEE
TLDKTKGRPAIKSFLVPREHPGVTIERLEEKLGIKASDTAVIRFDNARIPKDYILSDPEI
EECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCCCCC
NTEKGFGGVMSTFDNTRPIVAAMAVGVSRASLEELRKILEDAGIEISYDRPAHAQHAAAA
CCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHH
EFLRMEADWESSYLLTLRSAWQADNNVPNSMEASMAKAKAGRVGSDITLKAVEMAGTTGY
HHHHHCCCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCC
SERTLLEKWGRDSKILDIFEGTQQIQQLVVARRLLGLSSAELK
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]