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The map label for this gene is acdA [H]

Identifier: 169630567

GI number: 169630567

Start: 3527370

End: 3528782

Strand: Direct

Name: acdA [H]

Synonym: MAB_3486

Alternate gene names: 169630567

Gene position: 3527370-3528782 (Clockwise)

Preceding gene: 169630566

Following gene: 169630568

Centisome position: 69.61

GC content: 67.02

Gene sequence:

>1413_bases
ATGACCAACACGTTGACCCCGCGCGACGAGAAAAAGGCCGCCAAGAGCAAGAGCCTGGCGAAGCACGAGACCGGCGTCGG
CCTCCAGAAGCACAAGCGTGGCGCGATCGACATCCTCATCGCGGTGCTGACCCCGATCGCGGGCTCTGAGCTGCTGGACA
AGTACAACCTGCGCGGAGCCTTCAATAAGGGCATCTTCGAGAGCACGAAGGGCCTGTTCACCACCCTCGGCGTTGCCAAC
CGCACCTTCAAGAAGGTGACCGGCAGCAAGGGCGGACCCAAGCGCCTCGACAAGGCGAACGCCGACTACTTCGACCTCAA
CCCCGAGGACGAGCAGAAGATGATCGCCGACACGGTGAAGGAATTCGCCGTCGAGGTCATCCGCCCGGCCGCCTACGAGT
CGGACAAGAACAAGACCTACCCCGCCGACCTGCTGGGTAAGGTCGCCGAGCTGGGCGTCACCGCCATCAACATCCCCGAG
GATTTCGACGGCATCGCCTCGCAGCGCTCCACCGTCACCAACTCACTTGTCGCCGAGGCGCTTTCGTACGGTGACATGGG
CCTGGCCCTGCCGATCCTGGCTCCCTCGGGTGTGGCCAGCGCGCTGACCAACTGGGGCAGTGCCGACCAGCAGGCCACCT
ACCTCAAGGAGTTCGCGGGCGAGAACGTGCCGCAGGCCTCGGTCGTGATCGCCGAGCCGCAGGCCCTCTTCGATCCGTTC
AGCCTCAAGACCACGGCCACCCGCACCCCCAGCGGATTCCGCCTCAACGGCACCAAGTCGCTGGTCCCGGCCGCCGCGCA
GGCCGAGCTGTTCATTGTGGCCGCCAACTACAACGGCCGCCCGACGCTGTTCATCGTCGAGTCCGGCACCGAGGGCATCA
CCGTCGAGGAGGACCCGAGCATGGGCATCCGCGGCGCGGCACTGGGCCGGTTGAACCTCAACAATGTCGCGGTTCCCGCC
GCCAACATCCTCGGCGAAGAAGAAGGCAGCGACACGGCGCTCGCTAACTACTCCGAAGCCGTTGCCCTCGCCCGGCTGGG
TTGGGCATCGCTCGCGGTCGGCACCGGCCAGGCCGTGCTCGACTACGTGATCCCCTACGTGAAGCAGCGTGAGGCGTTCG
GTGAGCCCATCGCCCGCCGCCAGGCCGTTGCCTTCATGTGTGCCAACATCGCGATCGAGCTCGACGGCCTGCGCCTGGTC
ACCCTCCGCGGCGCCTCGCGCGCCGAGCAGGGCCTGCCCTTCGTCCGCGAGGCCGCACTGGCCCGCAAGCTGGCCACCGA
CAAGGGCATGCAGATCGGCCTGGACGGTGTGCAGCTGCTCGGCGGCCACGGCTTCACCAAGGAGCACCCGGTGGAGCGCT
GGTACCGCAACCTGCGCGCCATCGGTGTCGCCGAAGGCGTCGTTGTCCTGTAG

Upstream 100 bases:

>100_bases
GAGGATCTTACCGCTTAGTAAGATACGGTTCTTACTTCGGAGTAAGGTAACGACCAGATACTCCGGCAGAACCCCTTTGA
CCCCAGAAACGGCTGGTGAC

Downstream 100 bases:

>100_bases
CCATCCACTCCCCGGTCTTATCTACTAAACGAAAGTCTTTCCATGGCAATCAATTTGGAACTCCCCAAGAAGTTGCAGGC
CATCGTCGAGAAGGGGCATC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTNTLTPRDEKKAAKSKSLAKHETGVGLQKHKRGAIDILIAVLTPIAGSELLDKYNLRGAFNKGIFESTKGLFTTLGVAN
RTFKKVTGSKGGPKRLDKANADYFDLNPEDEQKMIADTVKEFAVEVIRPAAYESDKNKTYPADLLGKVAELGVTAINIPE
DFDGIASQRSTVTNSLVAEALSYGDMGLALPILAPSGVASALTNWGSADQQATYLKEFAGENVPQASVVIAEPQALFDPF
SLKTTATRTPSGFRLNGTKSLVPAAAQAELFIVAANYNGRPTLFIVESGTEGITVEEDPSMGIRGAALGRLNLNNVAVPA
ANILGEEEGSDTALANYSEAVALARLGWASLAVGTGQAVLDYVIPYVKQREAFGEPIARRQAVAFMCANIAIELDGLRLV
TLRGASRAEQGLPFVREAALARKLATDKGMQIGLDGVQLLGGHGFTKEHPVERWYRNLRAIGVAEGVVVL

Sequences:

>Translated_470_residues
MTNTLTPRDEKKAAKSKSLAKHETGVGLQKHKRGAIDILIAVLTPIAGSELLDKYNLRGAFNKGIFESTKGLFTTLGVAN
RTFKKVTGSKGGPKRLDKANADYFDLNPEDEQKMIADTVKEFAVEVIRPAAYESDKNKTYPADLLGKVAELGVTAINIPE
DFDGIASQRSTVTNSLVAEALSYGDMGLALPILAPSGVASALTNWGSADQQATYLKEFAGENVPQASVVIAEPQALFDPF
SLKTTATRTPSGFRLNGTKSLVPAAAQAELFIVAANYNGRPTLFIVESGTEGITVEEDPSMGIRGAALGRLNLNNVAVPA
ANILGEEEGSDTALANYSEAVALARLGWASLAVGTGQAVLDYVIPYVKQREAFGEPIARRQAVAFMCANIAIELDGLRLV
TLRGASRAEQGLPFVREAALARKLATDKGMQIGLDGVQLLGGHGFTKEHPVERWYRNLRAIGVAEGVVVL
>Mature_469_residues
TNTLTPRDEKKAAKSKSLAKHETGVGLQKHKRGAIDILIAVLTPIAGSELLDKYNLRGAFNKGIFESTKGLFTTLGVANR
TFKKVTGSKGGPKRLDKANADYFDLNPEDEQKMIADTVKEFAVEVIRPAAYESDKNKTYPADLLGKVAELGVTAINIPED
FDGIASQRSTVTNSLVAEALSYGDMGLALPILAPSGVASALTNWGSADQQATYLKEFAGENVPQASVVIAEPQALFDPFS
LKTTATRTPSGFRLNGTKSLVPAAAQAELFIVAANYNGRPTLFIVESGTEGITVEEDPSMGIRGAALGRLNLNNVAVPAA
NILGEEEGSDTALANYSEAVALARLGWASLAVGTGQAVLDYVIPYVKQREAFGEPIARRQAVAFMCANIAIELDGLRLVT
LRGASRAEQGLPFVREAALARKLATDKGMQIGLDGVQLLGGHGFTKEHPVERWYRNLRAIGVAEGVVVL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=32.0652173913043, Blast_Score=175, Evalue=7e-44,
Organism=Homo sapiens, GI4557233, Length=391, Percent_Identity=28.3887468030691, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI187960098, Length=373, Percent_Identity=29.4906166219839, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI4557231, Length=373, Percent_Identity=29.4906166219839, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=28.4552845528455, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI7656849, Length=365, Percent_Identity=26.8493150684932, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=29.0909090909091, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI4501857, Length=390, Percent_Identity=25.1282051282051, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4557235, Length=386, Percent_Identity=26.6839378238342, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI76496475, Length=386, Percent_Identity=26.6839378238342, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4503943, Length=362, Percent_Identity=26.2430939226519, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI7669494, Length=363, Percent_Identity=26.1707988980716, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI21361497, Length=349, Percent_Identity=25.214899713467, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI87081958, Length=366, Percent_Identity=25.9562841530055, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1786223, Length=370, Percent_Identity=25.4054054054054, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=362, Percent_Identity=31.767955801105, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=31.9672131147541, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=373, Percent_Identity=32.171581769437, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17534899, Length=373, Percent_Identity=32.7077747989276, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=29.4736842105263, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71990804, Length=303, Percent_Identity=30.3630363036304, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17533517, Length=380, Percent_Identity=26.8421052631579, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=378, Percent_Identity=24.6031746031746, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=25.8666666666667, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=30.1818181818182, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=30.379746835443, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=24.6073298429319, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=24.8663101604278, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=356, Percent_Identity=24.1573033707865, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=293, Percent_Identity=24.9146757679181, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666513, Length=366, Percent_Identity=33.3333333333333, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356377, Length=374, Percent_Identity=29.6791443850267, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24660351, Length=367, Percent_Identity=31.0626702997275, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24646207, Length=365, Percent_Identity=27.3972602739726, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21355753, Length=370, Percent_Identity=28.6486486486486, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281363737, Length=337, Percent_Identity=24.9258160237389, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19920834, Length=388, Percent_Identity=22.680412371134, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 50013; Mature: 49881

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTLTPRDEKKAAKSKSLAKHETGVGLQKHKRGAIDILIAVLTPIAGSELLDKYNLRGA
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCH
FNKGIFESTKGLFTTLGVANRTFKKVTGSKGGPKRLDKANADYFDLNPEDEQKMIADTVK
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEECCCCCHHHHHHHHHHH
EFAVEVIRPAAYESDKNKTYPADLLGKVAELGVTAINIPEDFDGIASQRSTVTNSLVAEA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
LSYGDMGLALPILAPSGVASALTNWGSADQQATYLKEFAGENVPQASVVIAEPQALFDPF
HHCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCHHHCCCC
SLKTTATRTPSGFRLNGTKSLVPAAAQAELFIVAANYNGRPTLFIVESGTEGITVEEDPS
CCCEECCCCCCCEEECCCHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCEEEECCCC
MGIRGAALGRLNLNNVAVPAANILGEEEGSDTALANYSEAVALARLGWASLAVGTGQAVL
CCCCCEEEEEECCCCEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCCHHHHH
DYVIPYVKQREAFGEPIARRQAVAFMCANIAIELDGLRLVTLRGASRAEQGLPFVREAAL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCEEEEEECCCCHHHHCCCHHHHHHH
ARKLATDKGMQIGLDGVQLLGGHGFTKEHPVERWYRNLRAIGVAEGVVVL
HHHHHHCCCCEECCCHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure 
TNTLTPRDEKKAAKSKSLAKHETGVGLQKHKRGAIDILIAVLTPIAGSELLDKYNLRGA
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCH
FNKGIFESTKGLFTTLGVANRTFKKVTGSKGGPKRLDKANADYFDLNPEDEQKMIADTVK
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEECCCCCHHHHHHHHHHH
EFAVEVIRPAAYESDKNKTYPADLLGKVAELGVTAINIPEDFDGIASQRSTVTNSLVAEA
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
LSYGDMGLALPILAPSGVASALTNWGSADQQATYLKEFAGENVPQASVVIAEPQALFDPF
HHCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCHHHCCCC
SLKTTATRTPSGFRLNGTKSLVPAAAQAELFIVAANYNGRPTLFIVESGTEGITVEEDPS
CCCEECCCCCCCEEECCCHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCEEEECCCC
MGIRGAALGRLNLNNVAVPAANILGEEEGSDTALANYSEAVALARLGWASLAVGTGQAVL
CCCCCEEEEEECCCCEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCCHHHHH
DYVIPYVKQREAFGEPIARRQAVAFMCANIAIELDGLRLVTLRGASRAEQGLPFVREAAL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCEEEEEECCCCHHHHCCCHHHHHHH
ARKLATDKGMQIGLDGVQLLGGHGFTKEHPVERWYRNLRAIGVAEGVVVL
HHHHHHCCCCEECCCHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]