BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is pnbA [H]

Identifier: 169630533

GI number: 169630533

Start: 3495269

End: 3496774

Strand: Reverse

Name: pnbA [H]

Synonym: MAB_3452c

Alternate gene names: 169630533

Gene position: 3496774-3495269 (Counterclockwise)

Preceding gene: 169630534

Following gene: 169630532

Centisome position: 69.01

GC content: 65.27

Gene sequence:

>1506_bases
ATGGCAAAGAAGCCCATCCGCATCAACACCGTCAACGGCACTGTCGAAGGATTCACCCGCGGCGGCGTGCACCGCTTCCG
TGGGATTCCCTACGCCGAGCCGCCGGTGGGTCCGTTGCGCCTGCGTGCGCCCCGGCCGGCCCTGCCGTGGACGGGGGTGC
GCACGTGTCGTGCGTGGGGAGCGGCGTCCATTCAGCAGCATCGCTACGCAATCATCTTGCCCGGCAAGCCGCAGAAGCTC
AGCGAGGACTGCCTTACTCTCAATGTCGTTGCCCCCGAGGGGCCGGTCAGTGGACCCTTGCCGGTCATGTTTTTCATCCA
CGGCGGTGGCTACTTCCTGGGCAGCTCGGCCACCCCGCTCTATGACGGGGCGAGCCTGGCGCGGCGGGGATGCGTGTACG
TCTCGGTCAACTATCGGCTGGGTGGGCTTGGCTGCGTTGACCTTTCCTCGTTGTCCGATGACAAGCACACCATTGACAGC
AACCTGTACCTGCGCGATTTGGTGCTCGCGCTGCAATGGGTGCACGACAACATCGGGGCCTTTGGCGGCGATCCCAACAA
CGTGACGATTTTCGGGGAGAGTGCCGGATCGCACGCGGTGAACACACTGCTCGCGGTGCCGTCGGCTGCGGGCTTGTTCC
ACCGGGCGATCTGCCAGAGCACTGCCAGTGGGCTGGTGGTCAGCGCCGAGGACGCGGCGGTGAATGCGCGTCAGTTCGCG
AAGTACCTCGGTGCCAGCGACTCGAACGCCGCGGCAACCGTGCTGGCGGCCAAGCCGAAGGATCTGGTGAAGGCGCTGTT
CCGGCTTATCGGGTCGGCCAAGCATGTACCGGGGCTATCGCTGCGGATCGGGCCGAGTATCGACGGAGATGTGTTGCCAC
AGGACCCGATCGAGGCTATGGAACGTGGTGAGTCACATCGTGTTCCACTCATCATCGGATACAACGCCGAAGAGGCCACC
CTGTTCACCAAGGTGCTCAAGATCCTGCCGATTACCCCGGAGGCACTCGAGCATTCCTTGTCCAAGGGCGGGCCCGACTT
CGTACGGCGCATCATCGAGGGCTACGACGGATATCCGTCGCAGCAGGCGCTGCTGCAGCTGGCCGGTGACCTGGCATTTG
GTTCGGCAGCGTGGCGGGTGGCCGAGGCGCACGGCCGGTACGCGCCGACGTACTTCTACCGGTATGACTACACGACACGG
GCACTGCGCCGTTATGGGCTGGGCCCCACCCACGCCATCGAACTGCTCGCGGTATTCGGCACGTACCGCACAGTTGCCGG
GCCGTTCCTCGCCGGGCGCGCAGACCGTGCCGTGGCACGTTCCGTGAGTGACGAGATGCAAAGGCGCTGGCTGGCTTTCG
CGCACACCGGAGTGCCCGGTGACGGTTGGCCCGCCCACACGGTGCCCGATCGTCAGGTGCTGATCATCGACAACCCGTCT
CGGTTGGAGGCTGATCCCGACGCGGACCGCCGCCCGCTATGGCAGGACGTCACCTCCATCGTCTAG

Upstream 100 bases:

>100_bases
TAGACCCGGAAGCCGCTCGGCGTGCGGCGTGGGAAGGCTTCAGTCTCACTCTCTAAATCCGCCATTGTGGCCCAACTGGT
TGGTTGCCTAGGATATGCCG

Downstream 100 bases:

>100_bases
CCCACACGCGGCGGTACGTTGGGCTTCATGATCATCGTGACGAGCAACGACATCCCCGGCTACAAGATCGCCGCGGTATT
CGGCGAGGTCTTCGGACTCA

Product: carboxylesterase LipT

Products: NA

Alternate protein names: Intracellular esterase B; PNB carboxy-esterase; PNBCE [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MAKKPIRINTVNGTVEGFTRGGVHRFRGIPYAEPPVGPLRLRAPRPALPWTGVRTCRAWGAASIQQHRYAIILPGKPQKL
SEDCLTLNVVAPEGPVSGPLPVMFFIHGGGYFLGSSATPLYDGASLARRGCVYVSVNYRLGGLGCVDLSSLSDDKHTIDS
NLYLRDLVLALQWVHDNIGAFGGDPNNVTIFGESAGSHAVNTLLAVPSAAGLFHRAICQSTASGLVVSAEDAAVNARQFA
KYLGASDSNAAATVLAAKPKDLVKALFRLIGSAKHVPGLSLRIGPSIDGDVLPQDPIEAMERGESHRVPLIIGYNAEEAT
LFTKVLKILPITPEALEHSLSKGGPDFVRRIIEGYDGYPSQQALLQLAGDLAFGSAAWRVAEAHGRYAPTYFYRYDYTTR
ALRRYGLGPTHAIELLAVFGTYRTVAGPFLAGRADRAVARSVSDEMQRRWLAFAHTGVPGDGWPAHTVPDRQVLIIDNPS
RLEADPDADRRPLWQDVTSIV

Sequences:

>Translated_501_residues
MAKKPIRINTVNGTVEGFTRGGVHRFRGIPYAEPPVGPLRLRAPRPALPWTGVRTCRAWGAASIQQHRYAIILPGKPQKL
SEDCLTLNVVAPEGPVSGPLPVMFFIHGGGYFLGSSATPLYDGASLARRGCVYVSVNYRLGGLGCVDLSSLSDDKHTIDS
NLYLRDLVLALQWVHDNIGAFGGDPNNVTIFGESAGSHAVNTLLAVPSAAGLFHRAICQSTASGLVVSAEDAAVNARQFA
KYLGASDSNAAATVLAAKPKDLVKALFRLIGSAKHVPGLSLRIGPSIDGDVLPQDPIEAMERGESHRVPLIIGYNAEEAT
LFTKVLKILPITPEALEHSLSKGGPDFVRRIIEGYDGYPSQQALLQLAGDLAFGSAAWRVAEAHGRYAPTYFYRYDYTTR
ALRRYGLGPTHAIELLAVFGTYRTVAGPFLAGRADRAVARSVSDEMQRRWLAFAHTGVPGDGWPAHTVPDRQVLIIDNPS
RLEADPDADRRPLWQDVTSIV
>Mature_500_residues
AKKPIRINTVNGTVEGFTRGGVHRFRGIPYAEPPVGPLRLRAPRPALPWTGVRTCRAWGAASIQQHRYAIILPGKPQKLS
EDCLTLNVVAPEGPVSGPLPVMFFIHGGGYFLGSSATPLYDGASLARRGCVYVSVNYRLGGLGCVDLSSLSDDKHTIDSN
LYLRDLVLALQWVHDNIGAFGGDPNNVTIFGESAGSHAVNTLLAVPSAAGLFHRAICQSTASGLVVSAEDAAVNARQFAK
YLGASDSNAAATVLAAKPKDLVKALFRLIGSAKHVPGLSLRIGPSIDGDVLPQDPIEAMERGESHRVPLIIGYNAEEATL
FTKVLKILPITPEALEHSLSKGGPDFVRRIIEGYDGYPSQQALLQLAGDLAFGSAAWRVAEAHGRYAPTYFYRYDYTTRA
LRRYGLGPTHAIELLAVFGTYRTVAGPFLAGRADRAVARSVSDEMQRRWLAFAHTGVPGDGWPAHTVPDRQVLIIDNPSR
LEADPDADRRPLWQDVTSIV

Specific function: Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol [H]

COG id: COG2272

COG function: function code I; Carboxylesterase type B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-B carboxylesterase/lipase family [H]

Homologues:

Organism=Homo sapiens, GI68508957, Length=516, Percent_Identity=32.7519379844961, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI68508965, Length=517, Percent_Identity=32.8820116054159, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI68508967, Length=517, Percent_Identity=32.8820116054159, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI37622885, Length=485, Percent_Identity=32.3711340206186, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI297747275, Length=497, Percent_Identity=32.9979879275654, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI33563374, Length=500, Percent_Identity=32.6, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI4557351, Length=533, Percent_Identity=30.0187617260788, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI37622887, Length=482, Percent_Identity=31.9502074688797, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI256222771, Length=527, Percent_Identity=31.1195445920304, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI24308209, Length=527, Percent_Identity=31.1195445920304, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI31317256, Length=527, Percent_Identity=31.1195445920304, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI298231153, Length=525, Percent_Identity=29.9047619047619, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI219521907, Length=525, Percent_Identity=29.9047619047619, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI7662470, Length=532, Percent_Identity=30.6390977443609, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI4557239, Length=519, Percent_Identity=29.6724470134875, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI7710112, Length=519, Percent_Identity=29.4797687861272, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI298231184, Length=527, Percent_Identity=26.5654648956357, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI298231188, Length=454, Percent_Identity=28.6343612334802, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI262359974, Length=505, Percent_Identity=30.8910891089109, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI21450749, Length=502, Percent_Identity=29.6812749003984, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI310117651, Length=503, Percent_Identity=30.6163021868787, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI310117649, Length=503, Percent_Identity=30.6163021868787, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI51593088, Length=525, Percent_Identity=29.5238095238095, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI148536848, Length=508, Percent_Identity=30.7086614173228, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI262359971, Length=545, Percent_Identity=28.6238532110092, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI30840978, Length=553, Percent_Identity=28.9330922242315, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI298231190, Length=271, Percent_Identity=33.5793357933579, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI310117653, Length=531, Percent_Identity=29.0018832391714, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI310117655, Length=400, Percent_Identity=30.5, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310117657, Length=417, Percent_Identity=29.9760191846523, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI55770862, Length=312, Percent_Identity=31.7307692307692, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI169216018, Length=222, Percent_Identity=36.036036036036, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI310133037, Length=222, Percent_Identity=36.036036036036, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI169215613, Length=222, Percent_Identity=36.036036036036, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17507681, Length=523, Percent_Identity=29.8279158699809, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI32566411, Length=522, Percent_Identity=30.2681992337165, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71999970, Length=531, Percent_Identity=28.4369114877589, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI86563868, Length=510, Percent_Identity=27.6470588235294, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17564872, Length=481, Percent_Identity=28.8981288981289, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17564870, Length=481, Percent_Identity=28.8981288981289, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17559616, Length=402, Percent_Identity=30.3482587064677, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17548187, Length=509, Percent_Identity=27.7013752455796, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17509963, Length=526, Percent_Identity=26.425855513308, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI193208562, Length=507, Percent_Identity=25.6410256410256, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17561818, Length=359, Percent_Identity=30.6406685236769, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17556436, Length=487, Percent_Identity=29.5687885010267, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17557304, Length=383, Percent_Identity=31.8537859007833, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI115534610, Length=506, Percent_Identity=27.6679841897233, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17558862, Length=399, Percent_Identity=28.3208020050125, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25146735, Length=224, Percent_Identity=36.1607142857143, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17557292, Length=300, Percent_Identity=31.3333333333333, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI193209277, Length=514, Percent_Identity=26.4591439688716, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17537193, Length=504, Percent_Identity=27.7777777777778, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32564350, Length=440, Percent_Identity=28.8636363636364, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17562340, Length=547, Percent_Identity=27.4223034734918, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17563740, Length=515, Percent_Identity=25.4368932038835, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17562530, Length=474, Percent_Identity=27.0042194092827, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17537191, Length=331, Percent_Identity=29.0030211480363, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI193209280, Length=515, Percent_Identity=25.2427184466019, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17557282, Length=404, Percent_Identity=28.960396039604, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17558864, Length=509, Percent_Identity=27.5049115913556, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI25146726, Length=271, Percent_Identity=31.3653136531365, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI71995288, Length=450, Percent_Identity=28.2222222222222, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17568173, Length=320, Percent_Identity=29.6875, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17542512, Length=491, Percent_Identity=25.8655804480652, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI72001551, Length=517, Percent_Identity=24.3713733075435, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17538680, Length=264, Percent_Identity=28.4090909090909, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25146759, Length=256, Percent_Identity=34.375, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI25146757, Length=256, Percent_Identity=34.375, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17564874, Length=248, Percent_Identity=34.6774193548387, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17566952, Length=339, Percent_Identity=26.8436578171091, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71981701, Length=277, Percent_Identity=29.2418772563177, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32565351, Length=209, Percent_Identity=32.5358851674641, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71981720, Length=249, Percent_Identity=29.718875502008, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71996781, Length=322, Percent_Identity=26.3975155279503, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25146753, Length=205, Percent_Identity=33.6585365853659, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17550574, Length=254, Percent_Identity=29.1338582677165, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193209734, Length=267, Percent_Identity=28.0898876404494, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115535198, Length=294, Percent_Identity=28.2312925170068, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71989495, Length=310, Percent_Identity=27.4193548387097, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI32566453, Length=358, Percent_Identity=23.7430167597765, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17550926, Length=358, Percent_Identity=23.7430167597765, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17737813, Length=497, Percent_Identity=31.58953722334, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24644835, Length=512, Percent_Identity=30.859375, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI28571561, Length=495, Percent_Identity=31.1111111111111, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI17737817, Length=497, Percent_Identity=29.9798792756539, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28573189, Length=542, Percent_Identity=29.8892988929889, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI17985995, Length=548, Percent_Identity=30.1094890510949, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28573188, Length=504, Percent_Identity=29.1666666666667, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24658187, Length=474, Percent_Identity=29.746835443038, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI221378204, Length=538, Percent_Identity=28.8104089219331, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24644839, Length=458, Percent_Identity=30.7860262008734, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI17737825, Length=459, Percent_Identity=30.9368191721133, Blast_Score=168, Evalue=8e-42,
Organism=Drosophila melanogaster, GI281361699, Length=568, Percent_Identity=29.5774647887324, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17136862, Length=568, Percent_Identity=29.5774647887324, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24649335, Length=542, Percent_Identity=30.4428044280443, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24649333, Length=542, Percent_Identity=30.4428044280443, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI161077134, Length=444, Percent_Identity=31.0810810810811, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24639611, Length=487, Percent_Identity=31.4168377823409, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24583084, Length=484, Percent_Identity=28.3057851239669, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24649337, Length=531, Percent_Identity=30.1318267419962, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI21356403, Length=552, Percent_Identity=28.804347826087, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281361279, Length=361, Percent_Identity=32.6869806094183, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24644854, Length=361, Percent_Identity=32.6869806094183, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571563, Length=530, Percent_Identity=28.1132075471698, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17737819, Length=423, Percent_Identity=30.4964539007092, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21358071, Length=496, Percent_Identity=27.0161290322581, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28574499, Length=462, Percent_Identity=27.9220779220779, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221473947, Length=544, Percent_Identity=26.8382352941176, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19920512, Length=340, Percent_Identity=33.5294117647059, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI281362121, Length=297, Percent_Identity=34.6801346801347, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281362119, Length=297, Percent_Identity=34.6801346801347, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281362123, Length=297, Percent_Identity=34.6801346801347, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363491, Length=366, Percent_Identity=31.9672131147541, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI161077136, Length=366, Percent_Identity=31.9672131147541, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI28574501, Length=325, Percent_Identity=28.3076923076923, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281361282, Length=357, Percent_Identity=30.5322128851541, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24582902, Length=530, Percent_Identity=29.0566037735849, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24665507, Length=323, Percent_Identity=30.6501547987616, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17136608, Length=323, Percent_Identity=30.6501547987616, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24584490, Length=329, Percent_Identity=31.0030395136778, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24584488, Length=329, Percent_Identity=31.0030395136778, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24584486, Length=329, Percent_Identity=31.0030395136778, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24584484, Length=329, Percent_Identity=31.0030395136778, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17136262, Length=329, Percent_Identity=31.0030395136778, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24582900, Length=313, Percent_Identity=32.2683706070287, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17647727, Length=254, Percent_Identity=33.0708661417323, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24762554, Length=548, Percent_Identity=22.992700729927, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17137794, Length=457, Percent_Identity=26.6958424507659, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24582896, Length=457, Percent_Identity=26.6958424507659, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24582898, Length=457, Percent_Identity=26.6958424507659, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19922254, Length=186, Percent_Identity=32.7956989247312, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644842, Length=118, Percent_Identity=37.2881355932203, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002018
- InterPro:   IPR019826
- InterPro:   IPR019819
- InterPro:   IPR000997 [H]

Pfam domain/function: PF00135 COesterase [H]

EC number: NA

Molecular weight: Translated: 53997; Mature: 53866

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00122 CARBOXYLESTERASE_B_1 ; PS00941 CARBOXYLESTERASE_B_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKPIRINTVNGTVEGFTRGGVHRFRGIPYAEPPVGPLRLRAPRPALPWTGVRTCRAWG
CCCCCEEEEECCCCCCCHHCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHCC
AASIQQHRYAIILPGKPQKLSEDCLTLNVVAPEGPVSGPLPVMFFIHGGGYFLGSSATPL
CCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCEEECCCCCCC
YDGASLARRGCVYVSVNYRLGGLGCVDLSSLSDDKHTIDSNLYLRDLVLALQWVHDNIGA
CCCHHHHHCCEEEEEEECEECCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCC
FGGDPNNVTIFGESAGSHAVNTLLAVPSAAGLFHRAICQSTASGLVVSAEDAAVNARQFA
CCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEECCHHHCCHHHHH
KYLGASDSNAAATVLAAKPKDLVKALFRLIGSAKHVPGLSLRIGPSIDGDVLPQDPIEAM
HHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHH
ERGESHRVPLIIGYNAEEATLFTKVLKILPITPEALEHSLSKGGPDFVRRIIEGYDGYPS
HCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCH
QQALLQLAGDLAFGSAAWRVAEAHGRYAPTYFYRYDYTTRALRRYGLGPTHAIELLAVFG
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHHHH
TYRTVAGPFLAGRADRAVARSVSDEMQRRWLAFAHTGVPGDGWPAHTVPDRQVLIIDNPS
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCC
RLEADPDADRRPLWQDVTSIV
CCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
AKKPIRINTVNGTVEGFTRGGVHRFRGIPYAEPPVGPLRLRAPRPALPWTGVRTCRAWG
CCCCEEEEECCCCCCCHHCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHCC
AASIQQHRYAIILPGKPQKLSEDCLTLNVVAPEGPVSGPLPVMFFIHGGGYFLGSSATPL
CCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCEEECCCCCCC
YDGASLARRGCVYVSVNYRLGGLGCVDLSSLSDDKHTIDSNLYLRDLVLALQWVHDNIGA
CCCHHHHHCCEEEEEEECEECCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCC
FGGDPNNVTIFGESAGSHAVNTLLAVPSAAGLFHRAICQSTASGLVVSAEDAAVNARQFA
CCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEECCHHHCCHHHHH
KYLGASDSNAAATVLAAKPKDLVKALFRLIGSAKHVPGLSLRIGPSIDGDVLPQDPIEAM
HHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHH
ERGESHRVPLIIGYNAEEATLFTKVLKILPITPEALEHSLSKGGPDFVRRIIEGYDGYPS
HCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCH
QQALLQLAGDLAFGSAAWRVAEAHGRYAPTYFYRYDYTTRALRRYGLGPTHAIELLAVFG
HHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHHHH
TYRTVAGPFLAGRADRAVARSVSDEMQRRWLAFAHTGVPGDGWPAHTVPDRQVLIIDNPS
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCC
RLEADPDADRRPLWQDVTSIV
CCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7828905; 8969506; 9384377; 10535917 [H]