Click here to switch to the map view.

The map label for this gene is codB [H]

Identifier: 169630513

GI number: 169630513

Start: 3477239

End: 3478564

Strand: Reverse

Name: codB [H]

Synonym: MAB_3432c

Alternate gene names: 169630513

Gene position: 3478564-3477239 (Counterclockwise)

Preceding gene: 169630514

Following gene: 169630512

Centisome position: 68.65

GC content: 64.63

Gene sequence:

>1326_bases
ATGACGATAAAAGCCGCCGCCACAGTAGATATCGACGTAATTTCCGCTGACGCACCCGAATCGCCGGCCTCGGAATACGA
GAATGAGCCGGTCCCACCGCACTCGCGACGAAGCCTGCTGTCCGTCGCGGCGGTGTGGCTCGGATTCCCGATGATCCTCA
CCTGCGCCGTTTTCGGTGGACTCATCGTCTATTCGTTGGGCTTCTGGCGCGGCATGCTGGCGATCGCATTGGGCAATGCC
GTCCTGACGGCCTACGTCGGAGCCTTGAGCTATCTGGCGGGCAAGACGGGAAAGAACTTCGGGCTCACCGCGATTGAGAC
GTTCGGGCGTGGCGGATACCGAGTGGTTTGCGGCTTCCTGGCCACCGTGGTGATCGGCTGGTTCGCATTCCAGACGGGTT
TGACGGGCTCGGTTCTGGCCACCTGTGCCGGATGGGATGCCCGGTGGACGGCGCTGGCCGCGGGCGTCGGATACGTAGCG
GTGACGCTCGTTGGCATCAGGGCGCTCTCAGCGATAGGGCTGATCGCGGCGCCGCTTTATCTACTGCTGGGCATCACGGC
AATCGTTCTAGCCCTGCGTGATTCGACGATCTCCGATGCGGTCGAGTACCGTGGGGGAGCGGGTGTTGCCGCCATGAGCA
TGGGCGCCGCGGTGACATTGGTAGTTGCCTGCTTCATCGATTCGGGAACCATGACCGCTGACTTCACGCGATGGTCTCGC
AATGGACGGCAAGGCTTTTGGGCTTCCGTTGCGGCCTTCCCGATCGGGAACTGTGCGGCCATGGTCGTCGGCGGTGTGAT
CGTCGCCCTGGGCGCCGCACGTTCACCCGCGACCGACGGCGGCAATTTCCTCGGTACGCTGATCGACACCGGCGGCTGGT
TGGTACCGGTGTCGATCGTGTTCGTCTTCGTGAACCTGGGCTCGGTCTGCACACATTGCCTGTACAACGGTGCCGTCGGA
TGGAGCCAGCTCACCGGTCACACGATGCGATTGCTTGCCGTGCTGTTGGGTGCGGCGGGAGTGTTGTTGGCCGTGCTGGG
AGTGTGGTCGCACTTCGAGCAGTGGCTGACGCTCTTGGGTGTGGTGGTTCCACCGATCGGGACGGTGCTCATCCTCGACC
AGTTGGTGTTGCCCCGTTTCGGGATAGCCGTCCGTGATGCCGCAATTCGTTGGGAGTCCTTCGGGGCGTGGGCGGCGGGC
GCGGCGTCGGCGTTGGCCGCCCACCTGTGGGCGCCGCAGCTTTCTGACGCCCTGACGGGAATCGCGACCGCCGCGCTTGT
GTACCTCGCAGCCGCTCGCGGCGCGCGGCGGGGCGTGCCGGCATGA

Upstream 100 bases:

>100_bases
CGCACGTCTAGGCGGCTCGACCCCGCGTACGTACCGTCGTCACTTACACGTAACCGGCGCGGACCGCGTACGCAACATCA
CGCCGAGATCCTGTGCGGCG

Downstream 100 bases:

>100_bases
CGGGGCAGGTCGACGCGCAGCCCTATCCGTGGCCGTTTGACGGCCCCGTGGATCCCGGTCGCACCGCCGTACTGTGCATC
GACTGGCAGGTCGACTTCTG

Product: cytosine permease

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTIKAAATVDIDVISADAPESPASEYENEPVPPHSRRSLLSVAAVWLGFPMILTCAVFGGLIVYSLGFWRGMLAIALGNA
VLTAYVGALSYLAGKTGKNFGLTAIETFGRGGYRVVCGFLATVVIGWFAFQTGLTGSVLATCAGWDARWTALAAGVGYVA
VTLVGIRALSAIGLIAAPLYLLLGITAIVLALRDSTISDAVEYRGGAGVAAMSMGAAVTLVVACFIDSGTMTADFTRWSR
NGRQGFWASVAAFPIGNCAAMVVGGVIVALGAARSPATDGGNFLGTLIDTGGWLVPVSIVFVFVNLGSVCTHCLYNGAVG
WSQLTGHTMRLLAVLLGAAGVLLAVLGVWSHFEQWLTLLGVVVPPIGTVLILDQLVLPRFGIAVRDAAIRWESFGAWAAG
AASALAAHLWAPQLSDALTGIATAALVYLAAARGARRGVPA

Sequences:

>Translated_441_residues
MTIKAAATVDIDVISADAPESPASEYENEPVPPHSRRSLLSVAAVWLGFPMILTCAVFGGLIVYSLGFWRGMLAIALGNA
VLTAYVGALSYLAGKTGKNFGLTAIETFGRGGYRVVCGFLATVVIGWFAFQTGLTGSVLATCAGWDARWTALAAGVGYVA
VTLVGIRALSAIGLIAAPLYLLLGITAIVLALRDSTISDAVEYRGGAGVAAMSMGAAVTLVVACFIDSGTMTADFTRWSR
NGRQGFWASVAAFPIGNCAAMVVGGVIVALGAARSPATDGGNFLGTLIDTGGWLVPVSIVFVFVNLGSVCTHCLYNGAVG
WSQLTGHTMRLLAVLLGAAGVLLAVLGVWSHFEQWLTLLGVVVPPIGTVLILDQLVLPRFGIAVRDAAIRWESFGAWAAG
AASALAAHLWAPQLSDALTGIATAALVYLAAARGARRGVPA
>Mature_440_residues
TIKAAATVDIDVISADAPESPASEYENEPVPPHSRRSLLSVAAVWLGFPMILTCAVFGGLIVYSLGFWRGMLAIALGNAV
LTAYVGALSYLAGKTGKNFGLTAIETFGRGGYRVVCGFLATVVIGWFAFQTGLTGSVLATCAGWDARWTALAAGVGYVAV
TLVGIRALSAIGLIAAPLYLLLGITAIVLALRDSTISDAVEYRGGAGVAAMSMGAAVTLVVACFIDSGTMTADFTRWSRN
GRQGFWASVAAFPIGNCAAMVVGGVIVALGAARSPATDGGNFLGTLIDTGGWLVPVSIVFVFVNLGSVCTHCLYNGAVGW
SQLTGHTMRLLAVLLGAAGVLLAVLGVWSHFEQWLTLLGVVVPPIGTVLILDQLVLPRFGIAVRDAAIRWESFGAWAAGA
ASALAAHLWAPQLSDALTGIATAALVYLAAARGARRGVPA

Specific function: Required for cytosine transport into the cell [H]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI1786530, Length=401, Percent_Identity=28.428927680798, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 45373; Mature: 45242

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKAAATVDIDVISADAPESPASEYENEPVPPHSRRSLLSVAAVWLGFPMILTCAVFGG
CCEEEEEEEEEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVYSLGFWRGMLAIALGNAVLTAYVGALSYLAGKTGKNFGLTAIETFGRGGYRVVCGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHH
ATVVIGWFAFQTGLTGSVLATCAGWDARWTALAAGVGYVAVTLVGIRALSAIGLIAAPLY
HHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLGITAIVLALRDSTISDAVEYRGGAGVAAMSMGAAVTLVVACFIDSGTMTADFTRWSR
HHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHC
NGRQGFWASVAAFPIGNCAAMVVGGVIVALGAARSPATDGGNFLGTLIDTGGWLVPVSIV
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHH
FVFVNLGSVCTHCLYNGAVGWSQLTGHTMRLLAVLLGAAGVLLAVLGVWSHFEQWLTLLG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVPPIGTVLILDQLVLPRFGIAVRDAAIRWESFGAWAAGAASALAAHLWAPQLSDALTG
HHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHH
IATAALVYLAAARGARRGVPA
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TIKAAATVDIDVISADAPESPASEYENEPVPPHSRRSLLSVAAVWLGFPMILTCAVFGG
CEEEEEEEEEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]