Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 169630443

GI number: 169630443

Start: 3412364

End: 3413320

Strand: Reverse

Name: etfA [H]

Synonym: MAB_3362c

Alternate gene names: 169630443

Gene position: 3413320-3412364 (Counterclockwise)

Preceding gene: 169630444

Following gene: 169630441

Centisome position: 67.36

GC content: 68.65

Gene sequence:

>957_bases
ATGGCTGAAGTACTTGTGCTCGTTGAGCATTCAGAGGGTGCGCTGAAGAAGGTCAGCGCCGAGCTCATCACCGCCGCCCG
CGTCCTGGGCGAGCCCTCGGCCGTCGTTGCCGGTCCCGCCGGTACCGCCGCGCCGCTGATCGACGGACTCAAGGAGGCCG
GCGCCGCCAAGATCTACGTCGCCGAGTCCGATGTCGTCGACAGCTACCTGGTGACCCCTAAGGTCGACATCCTTGCTGCG
CTGGCCGAAACCGCCAGCCCCGCGGGCATCCTGATCGCCGCCACCACCGAGGGCAAAGAGGTCGCCGGACGTCTGGCCGC
ACGCCTGGGCTCGGGCCTGCTGACCGACGTGGTCGAGGTCCGTGAGGGTGGCAAGGCTCTGCACTCGATCTTCGGTGGCG
CGTTCACCGTTGAGGCCCAGGCCAACGGCGATGCCCCTGTCATCACGGTGCGTCCGGGTGCGGTGGAAGCTGCGCCTGCC
GCCGGTGCGGGCGAGCAGGTCGCCGTCGAGGTACCCGCGCCCGCCGAGAACGCCACCAAGGTCACCTCTCGCCAGCCGGT
GGTCGGCGGCGACCGTCCGGAGCTCACCGAGGCCAGCATCGTCGTGTCCGGCGGTCGTGGTGTCGGTAGCGCCGACAAGT
TCAGCGTCGTGGAGGCTCTGGCCGACTCGCTCGGTGCCGCCGTCGGCGCCTCGCGTGCCGCCGTCGACTCGGGCTACTAC
CCGGGCCAGTTCCAGGTGGGTCAGACCGGTAAGACTGTGTCGCCTCAGCTGTACATCGCCCTGGGTATCTCGGGCGCCAT
CCAGCACCGCGCCGGTATGCAGACGTCGAAGACCATCGTCGCGGTCAACAAGGACGAGGAAGCCCCCATCTTCGAGATCG
CCGACTTCGGCGTGGTGGGCGATCTGTTCAACGTCGCACCGCAGCTCACCGACGCCGTGAAGGCCCGCAAGGGCTAA

Upstream 100 bases:

>100_bases
AGGGCGAGGGCGGCACCAAGGTCGCCGAATTCCTGGTTGCCCAAAAGATCATCTAAATCGACCCCCTTAATACCCAAACG
AGAGAGTAACGAGAATCGAT

Downstream 100 bases:

>100_bases
GTCCGTCTTCGGGACGGCTGACGTTACGCCACTGGACTATCCAGAGCCCCAGACCACCGCGTCGAGGGCGCTGGATAGTC
CTTTCGGCGTTCATGGGGAT

Product: electron transfer flavoprotein subunit alpha FixB

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAEVLVLVEHSEGALKKVSAELITAARVLGEPSAVVAGPAGTAAPLIDGLKEAGAAKIYVAESDVVDSYLVTPKVDILAA
LAETASPAGILIAATTEGKEVAGRLAARLGSGLLTDVVEVREGGKALHSIFGGAFTVEAQANGDAPVITVRPGAVEAAPA
AGAGEQVAVEVPAPAENATKVTSRQPVVGGDRPELTEASIVVSGGRGVGSADKFSVVEALADSLGAAVGASRAAVDSGYY
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADFGVVGDLFNVAPQLTDAVKARKG

Sequences:

>Translated_318_residues
MAEVLVLVEHSEGALKKVSAELITAARVLGEPSAVVAGPAGTAAPLIDGLKEAGAAKIYVAESDVVDSYLVTPKVDILAA
LAETASPAGILIAATTEGKEVAGRLAARLGSGLLTDVVEVREGGKALHSIFGGAFTVEAQANGDAPVITVRPGAVEAAPA
AGAGEQVAVEVPAPAENATKVTSRQPVVGGDRPELTEASIVVSGGRGVGSADKFSVVEALADSLGAAVGASRAAVDSGYY
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADFGVVGDLFNVAPQLTDAVKARKG
>Mature_317_residues
AEVLVLVEHSEGALKKVSAELITAARVLGEPSAVVAGPAGTAAPLIDGLKEAGAAKIYVAESDVVDSYLVTPKVDILAAL
AETASPAGILIAATTEGKEVAGRLAARLGSGLLTDVVEVREGGKALHSIFGGAFTVEAQANGDAPVITVRPGAVEAAPAA
GAGEQVAVEVPAPAENATKVTSRQPVVGGDRPELTEASIVVSGGRGVGSADKFSVVEALADSLGAAVGASRAAVDSGYYP
GQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADFGVVGDLFNVAPQLTDAVKARKG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=314, Percent_Identity=41.4012738853503, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI189181759, Length=270, Percent_Identity=42.2222222222222, Blast_Score=204, Evalue=1e-52,
Organism=Escherichia coli, GI1787990, Length=243, Percent_Identity=34.5679012345679, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786226, Length=250, Percent_Identity=35.2, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87082157, Length=238, Percent_Identity=31.9327731092437, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=315, Percent_Identity=38.7301587301587, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6325261, Length=323, Percent_Identity=34.6749226006192, Blast_Score=166, Evalue=6e-42,
Organism=Drosophila melanogaster, GI17136898, Length=314, Percent_Identity=41.4012738853503, Blast_Score=211, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24652801, Length=314, Percent_Identity=41.4012738853503, Blast_Score=211, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31823; Mature: 31692

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVLVLVEHSEGALKKVSAELITAARVLGEPSAVVAGPAGTAAPLIDGLKEAGAAKIYV
CCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCEEEEE
AESDVVDSYLVTPKVDILAALAETASPAGILIAATTEGKEVAGRLAARLGSGLLTDVVEV
ECCCCCCCEECCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHH
REGGKALHSIFGGAFTVEAQANGDAPVITVRPGAVEAAPAAGAGEQVAVEVPAPAENATK
HHCHHHHHHHHCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCC
VTSRQPVVGGDRPELTEASIVVSGGRGVGSADKFSVVEALADSLGAAVGASRAAVDSGYY
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADFGVVG
CCEEEECCCCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCEEEECCCCHHH
DLFNVAPQLTDAVKARKG
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEVLVLVEHSEGALKKVSAELITAARVLGEPSAVVAGPAGTAAPLIDGLKEAGAAKIYV
CEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCEEEEE
AESDVVDSYLVTPKVDILAALAETASPAGILIAATTEGKEVAGRLAARLGSGLLTDVVEV
ECCCCCCCEECCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHH
REGGKALHSIFGGAFTVEAQANGDAPVITVRPGAVEAAPAAGAGEQVAVEVPAPAENATK
HHCHHHHHHHHCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCC
VTSRQPVVGGDRPELTEASIVVSGGRGVGSADKFSVVEALADSLGAAVGASRAAVDSGYY
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
PGQFQVGQTGKTVSPQLYIALGISGAIQHRAGMQTSKTIVAVNKDEEAPIFEIADFGVVG
CCEEEECCCCCCCCCEEEEEEECCHHHHHHCCCCCCCEEEEECCCCCCCEEEECCCCHHH
DLFNVAPQLTDAVKARKG
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]