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The map label for this gene is desA1 [H]

Identifier: 169630435

GI number: 169630435

Start: 3402276

End: 3403262

Strand: Direct

Name: desA1 [H]

Synonym: MAB_3354

Alternate gene names: 169630435

Gene position: 3402276-3403262 (Clockwise)

Preceding gene: 169630431

Following gene: 169630436

Centisome position: 67.14

GC content: 62.51

Gene sequence:

>987_bases
ATGGCCCAGAAGGAATTCACCGACCTCGAGCTCCTACACGAGCTCGAACCCGTGGTCGAGGAGAACACTCATCGCCACCT
CGGCGTATTCAAAGAGTGGAACCCGCACGACTACATCCCCTGGTCGGACGGCAAGAACTACAAGGCCCTGGGCGGGCAGG
ACTGGGATCCGGAGCAGTGCAAGCTGTCCGAGGTCGCGAGGGTGGCCATGGTCACCAACCTGCTCACCGAGGACAACCTG
CCCGCCTATCACCGCGAGATCGCCATGAACTTCACCATGGACGGCCCGTGGGGCACCTGGGTCAACCGCTGGACCGCCGA
GGAAAACCGGCACAGCATCGCCATCCGCGACTACCTGGTGGTCACCCGCTCGGTGGACCCGGTGGAACTGGAGAAGCTAC
GGATGGAGCAGATGACCCGCGGCTTCTCCCCCGGCCAGAACCGCCAGGGCGGCGACGAACTCTTCGCCGAGAGCCTGTTC
GACTCGGTGGCCTACGTGTCCTTTCAAGAGTTGGCCACCCGCGTCTCGCACCGCAACACCGGGGTCGCGTGTGCCGAGCC
GATCGCGCAGGAGCTGCTCAAACACATCTCCAACGACGAGAACCTGCACATGATCTTCTACCGCAACATGGTCGAGGCAG
GTCTCGAGATCGCGCCCAACCAGGCGGTGAAATCCATCCATAAGGTGCTCGACAACTTCACGATGCCCGGCTACACGATT
CCTGGCTTTCGCCGCAATGCCGTCACCATCGCCACCGGCGGTGTCTACGACCCACAACTGCACCTTGCCGAGGTTGTGCA
ACCCGTGCTGCGTAAGTGGCGCATCTTCGAACGCGACGACATCAACGGTGAGGGCGAGTGGTACCGCGAAGACCTGGACC
GCATCATCACCGACCTCAAGAAGACGGCCTCCGACTTCGATGAGGTCAAGGCCAAGTACCTGGAACGCCAGGCCAAGCGC
GCAGAACGCCAGGCCGCCAAAGTCTAG

Upstream 100 bases:

>100_bases
CAGTGAGGGACCTTCGTCACTAGAGGCACCGCGGACATGCTCGGTCAAATATAAGTGTCACTTTCAGACACAGATAATCC
CGCAACCGAGGAACGCATCC

Downstream 100 bases:

>100_bases
CTCTCTCCGCTCCCCGTAACGTCGACATGGGCAAACGGCGATATGCCGTTCAGTACCATTGATCGGGGCCATCTTCCGGC
CGGCGGGTAGAAGAGGGAAT

Product: acyl-[acyl-carrier protein] desaturase DesA1

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA1 [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MAQKEFTDLELLHELEPVVEENTHRHLGVFKEWNPHDYIPWSDGKNYKALGGQDWDPEQCKLSEVARVAMVTNLLTEDNL
PAYHREIAMNFTMDGPWGTWVNRWTAEENRHSIAIRDYLVVTRSVDPVELEKLRMEQMTRGFSPGQNRQGGDELFAESLF
DSVAYVSFQELATRVSHRNTGVACAEPIAQELLKHISNDENLHMIFYRNMVEAGLEIAPNQAVKSIHKVLDNFTMPGYTI
PGFRRNAVTIATGGVYDPQLHLAEVVQPVLRKWRIFERDDINGEGEWYREDLDRIITDLKKTASDFDEVKAKYLERQAKR
AERQAAKV

Sequences:

>Translated_328_residues
MAQKEFTDLELLHELEPVVEENTHRHLGVFKEWNPHDYIPWSDGKNYKALGGQDWDPEQCKLSEVARVAMVTNLLTEDNL
PAYHREIAMNFTMDGPWGTWVNRWTAEENRHSIAIRDYLVVTRSVDPVELEKLRMEQMTRGFSPGQNRQGGDELFAESLF
DSVAYVSFQELATRVSHRNTGVACAEPIAQELLKHISNDENLHMIFYRNMVEAGLEIAPNQAVKSIHKVLDNFTMPGYTI
PGFRRNAVTIATGGVYDPQLHLAEVVQPVLRKWRIFERDDINGEGEWYREDLDRIITDLKKTASDFDEVKAKYLERQAKR
AERQAAKV
>Mature_327_residues
AQKEFTDLELLHELEPVVEENTHRHLGVFKEWNPHDYIPWSDGKNYKALGGQDWDPEQCKLSEVARVAMVTNLLTEDNLP
AYHREIAMNFTMDGPWGTWVNRWTAEENRHSIAIRDYLVVTRSVDPVELEKLRMEQMTRGFSPGQNRQGGDELFAESLFD
SVAYVSFQELATRVSHRNTGVACAEPIAQELLKHISNDENLHMIFYRNMVEAGLEIAPNQAVKSIHKVLDNFTMPGYTIP
GFRRNAVTIATGGVYDPQLHLAEVVQPVLRKWRIFERDDINGEGEWYREDLDRIITDLKKTASDFDEVKAKYLERQAKRA
ERQAAKV

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 37828; Mature: 37697

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKEFTDLELLHELEPVVEENTHRHLGVFKEWNPHDYIPWSDGKNYKALGGQDWDPEQC
CCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
KLSEVARVAMVTNLLTEDNLPAYHREIAMNFTMDGPWGTWVNRWTAEENRHSIAIRDYLV
HHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCHHHHHHHCCCCCCCEEEEEHEEE
VTRSVDPVELEKLRMEQMTRGFSPGQNRQGGDELFAESLFDSVAYVSFQELATRVSHRNT
EECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVACAEPIAQELLKHISNDENLHMIFYRNMVEAGLEIAPNQAVKSIHKVLDNFTMPGYTI
CCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCC
PGFRRNAVTIATGGVYDPQLHLAEVVQPVLRKWRIFERDDINGEGEWYREDLDRIITDLK
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KTASDFDEVKAKYLERQAKRAERQAAKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQKEFTDLELLHELEPVVEENTHRHLGVFKEWNPHDYIPWSDGKNYKALGGQDWDPEQC
CCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
KLSEVARVAMVTNLLTEDNLPAYHREIAMNFTMDGPWGTWVNRWTAEENRHSIAIRDYLV
HHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCHHHHHHHCCCCCCCEEEEEHEEE
VTRSVDPVELEKLRMEQMTRGFSPGQNRQGGDELFAESLFDSVAYVSFQELATRVSHRNT
EECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVACAEPIAQELLKHISNDENLHMIFYRNMVEAGLEIAPNQAVKSIHKVLDNFTMPGYTI
CCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCC
PGFRRNAVTIATGGVYDPQLHLAEVVQPVLRKWRIFERDDINGEGEWYREDLDRIITDLK
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KTASDFDEVKAKYLERQAKRAERQAAKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]