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The map label for this gene is baeS [H]

Identifier: 169630421

GI number: 169630421

Start: 3386749

End: 3387885

Strand: Direct

Name: baeS [H]

Synonym: MAB_3340

Alternate gene names: 169630421

Gene position: 3386749-3387885 (Clockwise)

Preceding gene: 169630420

Following gene: 169630424

Centisome position: 66.84

GC content: 67.37

Gene sequence:

>1137_bases
GTGACACGTCCCCGATACGGCATCGGCCTGCGCCTGCTGGTGGTGAACTCACTGGTGGTCCTGGCCGGAATAGCCACGAC
CAGCGTGGTCGCCGCGATCGTCGGGCCGCCGATGTTCCGCCGCCTCATGGATCAACAGGTATCGCCCGGCGCCGGGAACG
ATCACCCCTATGAGCGTGCCTTCCGCGATGCCACCGCGATGTCCATCGGGTTCGCGGTCGCGGTGTCGGCCCTGGCCGCG
CTCACGCTCAGTTGGTATCTGAGCCATCGAGTGCATCGCTCGGCCACCGCGCTGTCGCAGGCGGCCTCCGCCGTTGCCGA
CGGGAATTACGACATTCGGGTGCCGCCACCCCGGTTGGGCAAGGAATTCGACGCCGTCGCCGCGGCGTTCAACAAGATGG
CGCAGCGGCTCGGCGCGGTGGACGAGGCGCGTAGACAGATGCTGGCGGACCTGGCTCACGAGATACGGACGCCCGTGGCG
GTGCTTGAGGCGTACATGGAAGCGGTGGAAGACGGTGTGCAACAACTGGATCAGCAGACGGTCGCGACGCTACGGGACCA
GACCCGTCGACTGACGCGGTTCAGTATCGACGTCAACGCGCTGTCGGTCGCCGAGAGCCGCACCACGTCGATTGACGCGA
GATCGGTGTCTCCGGCCGATTTGGTCACTACCGCGGTCGCCGCGTTCGCGCCGCGCTATCAGACAAAGGGAGTCATCCTC
ACTTCTCACGCCGACGACGGGCTGCCCGATGTATGGGCCGATCCTGAACGCATGGGCCAGGTGCTGAGCAACCTGCTCGA
CAACGCCCTACGTCACACCGGCCCGGGCGGCCAGGTCACCGTGACGGCGACAGCGACCGGCACCGGCGCCACGATCGCCG
TCGCCGACACCGGCGACGGAGTTCCGGCCGAGCATCTGGACCGACTGTTCGATCGCTTCTATCGCGCCGATGCCGCCCGC
GATCGGCAGCACGGTGGAGCAGGTATCGGGTTGTCGATCGCCAAGGCACTTGTCGAGGCGCACGAGGGACGCATCGAGGC
GCACAGCGCGGGACACGCGGCCGGGACCACCTTCACCGTGTCTCTGCCCCGTCCGAGCGATCATCCGGAAAAAGCACCCG
GTCAGCGGCCCGGCTGA

Upstream 100 bases:

>100_bases
TCCACGTCGGGCATCTGCGTCAGAAGCTGGGCGATAGCCCCTCCCAGCCGCGATACGTGATGACCGTCCGCGGTGTCGGC
TATCGCATGGGGACCGGATC

Downstream 100 bases:

>100_bases
ATCACCGTGGGACGCGTCTTGGTGGCGGGGATGGTTGCCAGCGGCGCCTTGTTATCGGGGTCCGGCGCCGAGCTCATGTG
CGGGTCATTGGAGTGGATGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTRPRYGIGLRLLVVNSLVVLAGIATTSVVAAIVGPPMFRRLMDQQVSPGAGNDHPYERAFRDATAMSIGFAVAVSALAA
LTLSWYLSHRVHRSATALSQAASAVADGNYDIRVPPPRLGKEFDAVAAAFNKMAQRLGAVDEARRQMLADLAHEIRTPVA
VLEAYMEAVEDGVQQLDQQTVATLRDQTRRLTRFSIDVNALSVAESRTTSIDARSVSPADLVTTAVAAFAPRYQTKGVIL
TSHADDGLPDVWADPERMGQVLSNLLDNALRHTGPGGQVTVTATATGTGATIAVADTGDGVPAEHLDRLFDRFYRADAAR
DRQHGGAGIGLSIAKALVEAHEGRIEAHSAGHAAGTTFTVSLPRPSDHPEKAPGQRPG

Sequences:

>Translated_378_residues
MTRPRYGIGLRLLVVNSLVVLAGIATTSVVAAIVGPPMFRRLMDQQVSPGAGNDHPYERAFRDATAMSIGFAVAVSALAA
LTLSWYLSHRVHRSATALSQAASAVADGNYDIRVPPPRLGKEFDAVAAAFNKMAQRLGAVDEARRQMLADLAHEIRTPVA
VLEAYMEAVEDGVQQLDQQTVATLRDQTRRLTRFSIDVNALSVAESRTTSIDARSVSPADLVTTAVAAFAPRYQTKGVIL
TSHADDGLPDVWADPERMGQVLSNLLDNALRHTGPGGQVTVTATATGTGATIAVADTGDGVPAEHLDRLFDRFYRADAAR
DRQHGGAGIGLSIAKALVEAHEGRIEAHSAGHAAGTTFTVSLPRPSDHPEKAPGQRPG
>Mature_377_residues
TRPRYGIGLRLLVVNSLVVLAGIATTSVVAAIVGPPMFRRLMDQQVSPGAGNDHPYERAFRDATAMSIGFAVAVSALAAL
TLSWYLSHRVHRSATALSQAASAVADGNYDIRVPPPRLGKEFDAVAAAFNKMAQRLGAVDEARRQMLADLAHEIRTPVAV
LEAYMEAVEDGVQQLDQQTVATLRDQTRRLTRFSIDVNALSVAESRTTSIDARSVSPADLVTTAVAAFAPRYQTKGVILT
SHADDGLPDVWADPERMGQVLSNLLDNALRHTGPGGQVTVTATATGTGATIAVADTGDGVPAEHLDRLFDRFYRADAARD
RQHGGAGIGLSIAKALVEAHEGRIEAHSAGHAAGTTFTVSLPRPSDHPEKAPGQRPG

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=35.4243542435424, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786783, Length=278, Percent_Identity=31.294964028777, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786600, Length=257, Percent_Identity=33.852140077821, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=29.2, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790346, Length=275, Percent_Identity=27.6363636363636, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=29.3617021276596, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787894, Length=313, Percent_Identity=26.8370607028754, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789149, Length=354, Percent_Identity=26.271186440678, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=28.936170212766, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790861, Length=290, Percent_Identity=27.9310344827586, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788279, Length=297, Percent_Identity=24.5791245791246, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787374, Length=279, Percent_Identity=24.3727598566308, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=25.2, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790551, Length=334, Percent_Identity=26.0479041916168, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=330, Percent_Identity=25.7575757575758, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=25.7510729613734, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=31.4893617021277, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=28.4518828451883, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789808, Length=291, Percent_Identity=24.3986254295533, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40059; Mature: 39927

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPRYGIGLRLLVVNSLVVLAGIATTSVVAAIVGPPMFRRLMDQQVSPGAGNDHPYERA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHH
FRDATAMSIGFAVAVSALAALTLSWYLSHRVHRSATALSQAASAVADGNYDIRVPPPRLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHC
KEFDAVAAAFNKMAQRLGAVDEARRQMLADLAHEIRTPVAVLEAYMEAVEDGVQQLDQQT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VATLRDQTRRLTRFSIDVNALSVAESRTTSIDARSVSPADLVTTAVAAFAPRYQTKGVIL
HHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
TSHADDGLPDVWADPERMGQVLSNLLDNALRHTGPGGQVTVTATATGTGATIAVADTGDG
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCC
VPAEHLDRLFDRFYRADAARDRQHGGAGIGLSIAKALVEAHEGRIEAHSAGHAAGTTFTV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEE
SLPRPSDHPEKAPGQRPG
ECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRPRYGIGLRLLVVNSLVVLAGIATTSVVAAIVGPPMFRRLMDQQVSPGAGNDHPYERA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHH
FRDATAMSIGFAVAVSALAALTLSWYLSHRVHRSATALSQAASAVADGNYDIRVPPPRLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHC
KEFDAVAAAFNKMAQRLGAVDEARRQMLADLAHEIRTPVAVLEAYMEAVEDGVQQLDQQT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
VATLRDQTRRLTRFSIDVNALSVAESRTTSIDARSVSPADLVTTAVAAFAPRYQTKGVIL
HHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
TSHADDGLPDVWADPERMGQVLSNLLDNALRHTGPGGQVTVTATATGTGATIAVADTGDG
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCC
VPAEHLDRLFDRFYRADAARDRQHGGAGIGLSIAKALVEAHEGRIEAHSAGHAAGTTFTV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEE
SLPRPSDHPEKAPGQRPG
ECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]