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The map label for this gene is yycF [H]

Identifier: 169630420

GI number: 169630420

Start: 3386003

End: 3386752

Strand: Direct

Name: yycF [H]

Synonym: MAB_3339

Alternate gene names: 169630420

Gene position: 3386003-3386752 (Clockwise)

Preceding gene: 169630414

Following gene: 169630421

Centisome position: 66.82

GC content: 66.27

Gene sequence:

>750_bases
ATGGACGGTTCATCTCGCACTGCCGCCGCAGGTCCCGTACCGGACTACCGGGCACTGGTGGTCGACGACGAAGTGCCGCT
GGCAGAGGTGGTCGCCAGTTATCTCAAGCGAGAATCCTTCGAAGTTCATCTCGCACACGACGGCCGCCGCGCACTCGATC
TGGCGCGCGAGGTCGATCCCGACGTGGTGATCCTCGATATCGGCCTGCCCGGCGTGGACGGCATCGAGGTCTGCCGGCAA
CTCCGCGTCTTCTCAGACGCCTACGTGGTCATGCTGACCGCCCGCGACACCGAGGTGGACACCATCGTCGGCCTGTCGGT
GGGAGCCGACGATTACGTCACCAAGCCCTTCAGCCCGCGGGAGGTCGTCGCCCGGGTGCGCGCCATGCTCCGCCGGCCCC
GCCGCGCGCCGGAATCGCCAGCGGCAGTGACTCCGGAACTGAGCCCTCCCCGCGTCTTCGGAGCGTTGCGCATCAATGTC
GACGGCCGCGAGGTGCACGTCGGAGAAAGGCCAGTCACATTGACCCGCACGGAATTTGACGTCCTGGCCGCGCTGTCATC
CCGGCCGGGCATCGTGCTGAGCAGAAAGCAACTGCTCGACACGGTGTGGGGCGACACCTGGGTGGGCAACGACAACATTG
TCGATGTCCACGTCGGGCATCTGCGTCAGAAGCTGGGCGATAGCCCCTCCCAGCCGCGATACGTGATGACCGTCCGCGGT
GTCGGCTATCGCATGGGGACCGGATCGTGA

Upstream 100 bases:

>100_bases
CTATCGGTGCGCCAAGGAAACTCTGAAGTTTCGATGAAGAAACGCGGCCCAGGCACCGCGACCTTCGACCTGGGCCAAGC
TCTCGGTGCACCATTGGCGC

Downstream 100 bases:

>100_bases
CACGTCCCCGATACGGCATCGGCCTGCGCCTGCTGGTGGTGAACTCACTGGTGGTCCTGGCCGGAATAGCCACGACCAGC
GTGGTCGCCGCGATCGTCGG

Product: putative sensory transduction protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFEVHLAHDGRRALDLAREVDPDVVILDIGLPGVDGIEVCRQ
LRVFSDAYVVMLTARDTEVDTIVGLSVGADDYVTKPFSPREVVARVRAMLRRPRRAPESPAAVTPELSPPRVFGALRINV
DGREVHVGERPVTLTRTEFDVLAALSSRPGIVLSRKQLLDTVWGDTWVGNDNIVDVHVGHLRQKLGDSPSQPRYVMTVRG
VGYRMGTGS

Sequences:

>Translated_249_residues
MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFEVHLAHDGRRALDLAREVDPDVVILDIGLPGVDGIEVCRQ
LRVFSDAYVVMLTARDTEVDTIVGLSVGADDYVTKPFSPREVVARVRAMLRRPRRAPESPAAVTPELSPPRVFGALRINV
DGREVHVGERPVTLTRTEFDVLAALSSRPGIVLSRKQLLDTVWGDTWVGNDNIVDVHVGHLRQKLGDSPSQPRYVMTVRG
VGYRMGTGS
>Mature_249_residues
MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFEVHLAHDGRRALDLAREVDPDVVILDIGLPGVDGIEVCRQ
LRVFSDAYVVMLTARDTEVDTIVGLSVGADDYVTKPFSPREVVARVRAMLRRPRRAPESPAAVTPELSPPRVFGALRINV
DGREVHVGERPVTLTRTEFDVLAALSSRPGIVLSRKQLLDTVWGDTWVGNDNIVDVHVGHLRQKLGDSPSQPRYVMTVRG
VGYRMGTGS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=39.5652173913043, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=43.1718061674009, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=39.5652173913043, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=39.647577092511, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=41.4529914529915, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=33.1932773109244, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=36.480686695279, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=37.0044052863436, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=36.9565217391304, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693140, Length=225, Percent_Identity=32.8888888888889, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=33.9055793991416, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=31.140350877193, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=32.3275862068966, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=31.4410480349345, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=39.2523364485981, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27228; Mature: 27228

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFEVHLAHDGRRALDLAREVDP
CCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCC
DVVILDIGLPGVDGIEVCRQLRVFSDAYVVMLTARDTEVDTIVGLSVGADDYVTKPFSPR
CEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCHH
EVVARVRAMLRRPRRAPESPAAVTPELSPPRVFGALRINVDGREVHVGERPVTLTRTEFD
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCEEEECCCCEEEEECHHH
VLAALSSRPGIVLSRKQLLDTVWGDTWVGNDNIVDVHVGHLRQKLGDSPSQPRYVMTVRG
HHHHHCCCCCEEEEHHHHHHHHCCCEECCCCCEEEEEHHHHHHHHCCCCCCCEEEEEEEC
VGYRMGTGS
CCEECCCCC
>Mature Secondary Structure
MDGSSRTAAAGPVPDYRALVVDDEVPLAEVVASYLKRESFEVHLAHDGRRALDLAREVDP
CCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCC
DVVILDIGLPGVDGIEVCRQLRVFSDAYVVMLTARDTEVDTIVGLSVGADDYVTKPFSPR
CEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCHH
EVVARVRAMLRRPRRAPESPAAVTPELSPPRVFGALRINVDGREVHVGERPVTLTRTEFD
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCEEEECCCCEEEEECHHH
VLAALSSRPGIVLSRKQLLDTVWGDTWVGNDNIVDVHVGHLRQKLGDSPSQPRYVMTVRG
HHHHHCCCCCEEEEHHHHHHHHCCCEECCCCCEEEEEHHHHHHHHCCCCCCCEEEEEEEC
VGYRMGTGS
CCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]