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The map label for this gene is bioI [H]

Identifier: 169630397

GI number: 169630397

Start: 3354641

End: 3355822

Strand: Direct

Name: bioI [H]

Synonym: MAB_3316

Alternate gene names: 169630397

Gene position: 3354641-3355822 (Clockwise)

Preceding gene: 169630396

Following gene: 169630399

Centisome position: 66.2

GC content: 64.64

Gene sequence:

>1182_bases
ATGACCACTGCTAACCCCGTCACCCCGCGAATCCCCTGGGATTCCCGAGATCCTTATGTCTACCTCGAAGACTTACGAGC
CCACGGTGACGTGGTCTTAGACGAAAATGCCGGTACCTGGGTGGTTCTCGGCTATCAGCCCGCCCGCGAGGTGCTAGGTG
GTTCCGGCTGGTCGAGCGATCCACTCGCAAGCCCCCAGCTGCGGGCACAGGCTCCCGAATTCCTCGATTCGTCCGGCTTC
GGCAGGAACATGCTCTTCGCCGACGAACCAGACCACACCGAGCTCAGGGGGACCGTCCGCGACGTGTTCACCCCAGGGTT
CATCGCCGGCCTGCGGGAGGGCGTACACACCATCGCCTCGCATGTTGTCGAATACCCCTCCACAGGAGAATATTTCGACT
TCATGGCCGATATCGCCCTGCCTCTGCCGATCGCCATCATCGGCGAATGGCTTGGCCTCGACGACTCGTCGGCCGCTGTC
CTGCGCCAGGAATCCCCGGCCATCATTCAGATGCTCGGCGCCTTCGCCGACGTCGATACGGTCATGGCTGGCACCGCCGC
CGGCGTCACCCTCGCCACCGAACTACTGCCTCTGGCGGCCGACCGCCGCGCACACCCGGGCGACGACCTGCTCAGCCTGA
TCGCGTCCAACACCGACCTACCCCTGGAAGACGTCGTCACAACGGCCCTCATTATCGCCATAGCGGGCCATGAGACAACG
GCAAACCTGTTAGGAGCAAGCATGGTTCGGCTGCTGACTCCACGTCCCGACGGCACCCGGCTGGCAGATGATATCGATCC
TGACGACCCCACGGTTATCACCGAGCTGCTTCGGCTGGACGGTCCGGTCCTGGCCACCGCACGCGTGGCGACCAGGGCAC
ACACCCTCGCCGGCAATACCATAGAGGGGGGACAGACTGTGTTGATCGCGATTGCCGCCGCCAACCGCGATCCACAGGTG
TTCGTGGACCCCGCCGTCTTCCGGCGTGATCGCACGAGCCCGCCACTGGCCTTCGGGTACGGCACACACCACTGCCTGGG
CTCGGCGCTGGCCCGGCTGGAGACCACGTTAGTCCTGCGCGAGGTGCTGGCACGTCAACCGGTGATAACAGGCCCCGTAA
GCTGGCGCGACACTCCCGCGATTCGGGGACCACGCAGCATCCCGATGCGCTTCCAAACGTAG

Upstream 100 bases:

>100_bases
CTCGATGATCTCGACGGGGTCGGCGAACCCGTTTCCCCGTTAGGTAGACAGCATATCGCGTGGGTGCGTGACCGCGGCCT
ACCCTTCGGATTGGATCGCC

Downstream 100 bases:

>100_bases
CTGACGCTGCCGCATAGGAATCATCTGCGCCGCTACAACAATCCGAGCATCTGCAGATCGGTGACGTATTTGAGAATGAT
CGGTGCCGAGATATGTGGAA

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTTANPVTPRIPWDSRDPYVYLEDLRAHGDVVLDENAGTWVVLGYQPAREVLGGSGWSSDPLASPQLRAQAPEFLDSSGF
GRNMLFADEPDHTELRGTVRDVFTPGFIAGLREGVHTIASHVVEYPSTGEYFDFMADIALPLPIAIIGEWLGLDDSSAAV
LRQESPAIIQMLGAFADVDTVMAGTAAGVTLATELLPLAADRRAHPGDDLLSLIASNTDLPLEDVVTTALIIAIAGHETT
ANLLGASMVRLLTPRPDGTRLADDIDPDDPTVITELLRLDGPVLATARVATRAHTLAGNTIEGGQTVLIAIAAANRDPQV
FVDPAVFRRDRTSPPLAFGYGTHHCLGSALARLETTLVLREVLARQPVITGPVSWRDTPAIRGPRSIPMRFQT

Sequences:

>Translated_393_residues
MTTANPVTPRIPWDSRDPYVYLEDLRAHGDVVLDENAGTWVVLGYQPAREVLGGSGWSSDPLASPQLRAQAPEFLDSSGF
GRNMLFADEPDHTELRGTVRDVFTPGFIAGLREGVHTIASHVVEYPSTGEYFDFMADIALPLPIAIIGEWLGLDDSSAAV
LRQESPAIIQMLGAFADVDTVMAGTAAGVTLATELLPLAADRRAHPGDDLLSLIASNTDLPLEDVVTTALIIAIAGHETT
ANLLGASMVRLLTPRPDGTRLADDIDPDDPTVITELLRLDGPVLATARVATRAHTLAGNTIEGGQTVLIAIAAANRDPQV
FVDPAVFRRDRTSPPLAFGYGTHHCLGSALARLETTLVLREVLARQPVITGPVSWRDTPAIRGPRSIPMRFQT
>Mature_392_residues
TTANPVTPRIPWDSRDPYVYLEDLRAHGDVVLDENAGTWVVLGYQPAREVLGGSGWSSDPLASPQLRAQAPEFLDSSGFG
RNMLFADEPDHTELRGTVRDVFTPGFIAGLREGVHTIASHVVEYPSTGEYFDFMADIALPLPIAIIGEWLGLDDSSAAVL
RQESPAIIQMLGAFADVDTVMAGTAAGVTLATELLPLAADRRAHPGDDLLSLIASNTDLPLEDVVTTALIIAIAGHETTA
NLLGASMVRLLTPRPDGTRLADDIDPDDPTVITELLRLDGPVLATARVATRAHTLAGNTIEGGQTVLIAIAAANRDPQVF
VDPAVFRRDRTSPPLAFGYGTHHCLGSALARLETTLVLREVLARQPVITGPVSWRDTPAIRGPRSIPMRFQT

Specific function: Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 42093; Mature: 41962

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTANPVTPRIPWDSRDPYVYLEDLRAHGDVVLDENAGTWVVLGYQPAREVLGGSGWSSD
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCEEEEECCCHHHHHHCCCCCCCC
PLASPQLRAQAPEFLDSSGFGRNMLFADEPDHTELRGTVRDVFTPGFIAGLREGVHTIAS
CCCCCHHHHCCCHHHCCCCCCCCCEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
HVVEYPSTGEYFDFMADIALPLPIAIIGEWLGLDDSSAAVLRQESPAIIQMLGAFADVDT
HHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
VMAGTAAGVTLATELLPLAADRRAHPGDDLLSLIASNTDLPLEDVVTTALIIAIAGHETT
HHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHH
ANLLGASMVRLLTPRPDGTRLADDIDPDDPTVITELLRLDGPVLATARVATRAHTLAGNT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
IEGGQTVLIAIAAANRDPQVFVDPAVFRRDRTSPPLAFGYGTHHCLGSALARLETTLVLR
CCCCCEEEEEEEECCCCCEEEECHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
EVLARQPVITGPVSWRDTPAIRGPRSIPMRFQT
HHHHCCCEEECCCCCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure 
TTANPVTPRIPWDSRDPYVYLEDLRAHGDVVLDENAGTWVVLGYQPAREVLGGSGWSSD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCEEEEECCCHHHHHHCCCCCCCC
PLASPQLRAQAPEFLDSSGFGRNMLFADEPDHTELRGTVRDVFTPGFIAGLREGVHTIAS
CCCCCHHHHCCCHHHCCCCCCCCCEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
HVVEYPSTGEYFDFMADIALPLPIAIIGEWLGLDDSSAAVLRQESPAIIQMLGAFADVDT
HHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
VMAGTAAGVTLATELLPLAADRRAHPGDDLLSLIASNTDLPLEDVVTTALIIAIAGHETT
HHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHH
ANLLGASMVRLLTPRPDGTRLADDIDPDDPTVITELLRLDGPVLATARVATRAHTLAGNT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
IEGGQTVLIAIAAANRDPQVFVDPAVFRRDRTSPPLAFGYGTHHCLGSALARLETTLVLR
CCCCCEEEEEEEECCCCCEEEECHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
EVLARQPVITGPVSWRDTPAIRGPRSIPMRFQT
HHHHCCCEEECCCCCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8763940; 9387221; 9384377 [H]