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The map label for this gene is recG [H]

Identifier: 169630359

GI number: 169630359

Start: 3315418

End: 3317658

Strand: Reverse

Name: recG [H]

Synonym: MAB_3278c

Alternate gene names: 169630359

Gene position: 3317658-3315418 (Counterclockwise)

Preceding gene: 169630360

Following gene: 169630358

Centisome position: 65.47

GC content: 64.21

Gene sequence:

>2241_bases
GTGGCAAAACTTTCCGATCGCCTGGATCATGTATTGGGAAACAAGGCATCCGACGTTCTCGATGCCGAATTCGGTCTGAT
TACTGTCGAAGACCTTCTTCACCACTACCCGCGCCGATACAGCACTGACTTCAGCCTGCGCGATGAACAGGACGGCGAAA
GCGCCAAGCCTGGGGAACACACCACGCTGGTGGGATTCATCACCTCTGCGGAGCTGAAGAGAATGCGTAACCGCAAGGGG
CAGTTCCTCTCCGTCACGCTGGGCAGTGCACCGCATGCCGTACAGGCCACCTTCTTTCACCCGCACAAGGTGAAACGTGA
CCTGCAGGTAGGTAATCGGGTGATGCTCTCAGGCGCTGTCGGGGAGTTTCGGGGCAAGCCCCAGTTGACCCACCCCGACT
ATTTGGTGCTGGAAACCGCGCTCGGGGAGAGCACCGAAACGCGGGGAAGCACCGCGCTGCGCGGCATCGCCGGGGCCGCT
CGGGATGCCTCCACGGCCATCTCGGCCTTCCAGCGCAATGTGTTTCCGATCTACCCGGCAACCAAGAACCTGGAGAGCTG
GGATATCTACCGCTGCATCGACCAGGTGCTCACCCAGTTGGATCCGGTGCCCGAGGCGCTGCCGGACGCGGTATTGGCAG
AGTACGGTCTGATGTCCCTCGATGAGGCGCTGCGCAAGATCCACATGTCGGAGGACGCCTCCGAACAGAAGCAGGCGCGC
CGCCGGCTGGCGTTCGATGAGGCGCTGGGTCTGCAACTGGCGTTGGCCATGCGGCGCGGCAGTGAGATCGGTTCGGCGGG
CCCGCCGATGCCACTGGCCCAAGCCGGGCTGCGTGCAGATCTTTTGGGCCAGTTGCCCTTCGACCTTACCGAGGGGCAGC
GCCACGTCGTGGCAGAAATCGGGGAAGACCTCGCTGGGGTCAAGCCGATGAACAGGCTGCTTCAGGGCGAGGTCGGCTCC
GGTAAGACTGTCGTCGCATTGCTGGCGATGATGCAGGCTATCGATGCCGGGTATCAGTGTGCGCTGCTCGCGCCCACCGA
GGTGTTGGCGGTTCAGCATGCCCGATCACTGCGAGCGATGCTCGGATCTTTAGCGACGGCGGGGGAATTGGGTGCACCCG
ACGATGCGACCAGCATCGCGCTGCTCACCGGTTCGATGTCGCCTGCGGTGAAGAAGCAGATCAAGGCCGATGTGGCGACC
GGCCTAGCGGGCATCGTCATCGGAACTCATGCGCTGCTGCAGGACTCGGTGGACTTTCACAATCTGGGCCTGGTGGTTGT
GGACGAGCAGCACCGCTTCGGCGTCGAACAGCGGGATCGCTTGCGGGCCAAGGCTTCGCAAGGCATCGTGCCGCACCTGT
TGGTGATGACGGCCACGCCTATCCCGCGTACGGTGGCGCTCACCGTGTTCGGCGATCTGGAGACCTCCACGTTGCGCGAG
CTTCCGCGGGGGCGGCAACCCATCACCACGACAGCGGTGTTCACTCGCGAGAAGCCGGGCTGGCTCGCCCGCGGCTGGGA
GCGGATCGCCGAGGAGGTCGCCGCGGGCCGGCAGGCCTACGTGGTGGCCTCGCGAATCGACGCCGACGACAAAGACTCCG
GTCCGGAAGAGGCGGAGGAGAAGCGTCCGCCGCCGGTCCCGGTCACCGAGTTGTATGAGACCATCCGTGGCTCGCTGCTT
CCCGGGCTACGGATCGGTCTGCTGCATGGACGGCTGCCCTCGGAGCAGAAGGACGCCGTGATGACGGCGTTCAACGCGGG
CGAGATCGATGTCCTGGTGTGTACGACAGTGATTGAGGTCGGTGTGGACGTGCCCAACGCCACCGTGATGCTCATCATGG
ATGCCGATAGGTTCGGAATCAGCCAGTTGCATCAGCTGCGGGGCCGGGTTGGCCGTGGTGGCAATAAGGGGCTGTGCCTT
TTGGTCAGCCCTTGCAGCCCAGCGGGCTCGGCCGGGCGCCGGTTGCGTGCGGTGCAGGACACTCTCGATGGGTTCACGCT
TGCCGAGCTGGACTTGGAGGAGCGGCGTGAGGGTGATGTCTTGGGGCGTGACCAGTCTGGGCGCGCGGTGAACCTCCGGC
TGCTTTCGCTGCTGGATCACCGCGACATGATCGAGACGGCGCGGGAGATGGCGATGCGTGCCTGTGCGGACGATCCTGAG
CTGGCGCAGCAACCCGCTTTGGCGGGTATGGCTCGGCGTTTCCTGGTAGCCGATCAGATCGAGTACCTGGACAAGTCGTG
A

Upstream 100 bases:

>100_bases
CGAGCACACCCGGTCGCATCACGGAGGCGTCGAGGTGATGATCTACCGCACCGGGCAGCACACCGACGTGGTTCACATCG
GTGTCGAGTGACGGGGAATA

Downstream 100 bases:

>100_bases
GTAATCGCACCATGCTCATCGTCGCCATCGCAGCGGCGATCGCGGTGGTGGTGGCGTATCAGGTGTCGACTCGATACCGC
TTGCTACGTGCTAATGCTGT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 746; Mature: 745

Protein sequence:

>746_residues
MAKLSDRLDHVLGNKASDVLDAEFGLITVEDLLHHYPRRYSTDFSLRDEQDGESAKPGEHTTLVGFITSAELKRMRNRKG
QFLSVTLGSAPHAVQATFFHPHKVKRDLQVGNRVMLSGAVGEFRGKPQLTHPDYLVLETALGESTETRGSTALRGIAGAA
RDASTAISAFQRNVFPIYPATKNLESWDIYRCIDQVLTQLDPVPEALPDAVLAEYGLMSLDEALRKIHMSEDASEQKQAR
RRLAFDEALGLQLALAMRRGSEIGSAGPPMPLAQAGLRADLLGQLPFDLTEGQRHVVAEIGEDLAGVKPMNRLLQGEVGS
GKTVVALLAMMQAIDAGYQCALLAPTEVLAVQHARSLRAMLGSLATAGELGAPDDATSIALLTGSMSPAVKKQIKADVAT
GLAGIVIGTHALLQDSVDFHNLGLVVVDEQHRFGVEQRDRLRAKASQGIVPHLLVMTATPIPRTVALTVFGDLETSTLRE
LPRGRQPITTTAVFTREKPGWLARGWERIAEEVAAGRQAYVVASRIDADDKDSGPEEAEEKRPPPVPVTELYETIRGSLL
PGLRIGLLHGRLPSEQKDAVMTAFNAGEIDVLVCTTVIEVGVDVPNATVMLIMDADRFGISQLHQLRGRVGRGGNKGLCL
LVSPCSPAGSAGRRLRAVQDTLDGFTLAELDLEERREGDVLGRDQSGRAVNLRLLSLLDHRDMIETAREMAMRACADDPE
LAQQPALAGMARRFLVADQIEYLDKS

Sequences:

>Translated_746_residues
MAKLSDRLDHVLGNKASDVLDAEFGLITVEDLLHHYPRRYSTDFSLRDEQDGESAKPGEHTTLVGFITSAELKRMRNRKG
QFLSVTLGSAPHAVQATFFHPHKVKRDLQVGNRVMLSGAVGEFRGKPQLTHPDYLVLETALGESTETRGSTALRGIAGAA
RDASTAISAFQRNVFPIYPATKNLESWDIYRCIDQVLTQLDPVPEALPDAVLAEYGLMSLDEALRKIHMSEDASEQKQAR
RRLAFDEALGLQLALAMRRGSEIGSAGPPMPLAQAGLRADLLGQLPFDLTEGQRHVVAEIGEDLAGVKPMNRLLQGEVGS
GKTVVALLAMMQAIDAGYQCALLAPTEVLAVQHARSLRAMLGSLATAGELGAPDDATSIALLTGSMSPAVKKQIKADVAT
GLAGIVIGTHALLQDSVDFHNLGLVVVDEQHRFGVEQRDRLRAKASQGIVPHLLVMTATPIPRTVALTVFGDLETSTLRE
LPRGRQPITTTAVFTREKPGWLARGWERIAEEVAAGRQAYVVASRIDADDKDSGPEEAEEKRPPPVPVTELYETIRGSLL
PGLRIGLLHGRLPSEQKDAVMTAFNAGEIDVLVCTTVIEVGVDVPNATVMLIMDADRFGISQLHQLRGRVGRGGNKGLCL
LVSPCSPAGSAGRRLRAVQDTLDGFTLAELDLEERREGDVLGRDQSGRAVNLRLLSLLDHRDMIETAREMAMRACADDPE
LAQQPALAGMARRFLVADQIEYLDKS
>Mature_745_residues
AKLSDRLDHVLGNKASDVLDAEFGLITVEDLLHHYPRRYSTDFSLRDEQDGESAKPGEHTTLVGFITSAELKRMRNRKGQ
FLSVTLGSAPHAVQATFFHPHKVKRDLQVGNRVMLSGAVGEFRGKPQLTHPDYLVLETALGESTETRGSTALRGIAGAAR
DASTAISAFQRNVFPIYPATKNLESWDIYRCIDQVLTQLDPVPEALPDAVLAEYGLMSLDEALRKIHMSEDASEQKQARR
RLAFDEALGLQLALAMRRGSEIGSAGPPMPLAQAGLRADLLGQLPFDLTEGQRHVVAEIGEDLAGVKPMNRLLQGEVGSG
KTVVALLAMMQAIDAGYQCALLAPTEVLAVQHARSLRAMLGSLATAGELGAPDDATSIALLTGSMSPAVKKQIKADVATG
LAGIVIGTHALLQDSVDFHNLGLVVVDEQHRFGVEQRDRLRAKASQGIVPHLLVMTATPIPRTVALTVFGDLETSTLREL
PRGRQPITTTAVFTREKPGWLARGWERIAEEVAAGRQAYVVASRIDADDKDSGPEEAEEKRPPPVPVTELYETIRGSLLP
GLRIGLLHGRLPSEQKDAVMTAFNAGEIDVLVCTTVIEVGVDVPNATVMLIMDADRFGISQLHQLRGRVGRGGNKGLCLL
VSPCSPAGSAGRRLRAVQDTLDGFTLAELDLEERREGDVLGRDQSGRAVNLRLLSLLDHRDMIETAREMAMRACADDPEL
AQQPALAGMARRFLVADQIEYLDKS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=714, Percent_Identity=36.8347338935574, Blast_Score=352, Evalue=4e-98,
Organism=Escherichia coli, GI1787357, Length=408, Percent_Identity=35.7843137254902, Blast_Score=223, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 80787; Mature: 80656

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLSDRLDHVLGNKASDVLDAEFGLITVEDLLHHYPRRYSTDFSLRDEQDGESAKPGEH
CCCHHHHHHHHHCCCHHHHHHCCCCEEEHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCC
TTLVGFITSAELKRMRNRKGQFLSVTLGSAPHAVQATFFHPHKVKRDLQVGNRVMLSGAV
EEEEEEHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECHHHHHHHHHHCCEEEEECCH
GEFRGKPQLTHPDYLVLETALGESTETRGSTALRGIAGAARDASTAISAFQRNVFPIYPA
HHCCCCCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCEEECCC
TKNLESWDIYRCIDQVLTQLDPVPEALPDAVLAEYGLMSLDEALRKIHMSEDASEQKQAR
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RRLAFDEALGLQLALAMRRGSEIGSAGPPMPLAQAGLRADLLGQLPFDLTEGQRHVVAEI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCCCHHHHHHH
GEDLAGVKPMNRLLQGEVGSGKTVVALLAMMQAIDAGYQCALLAPTEVLAVQHARSLRAM
HHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
LGSLATAGELGAPDDATSIALLTGSMSPAVKKQIKADVATGLAGIVIGTHALLQDSVDFH
HHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
NLGLVVVDEQHRFGVEQRDRLRAKASQGIVPHLLVMTATPIPRTVALTVFGDLETSTLRE
HCCEEEECCHHHCCCCHHHHHHHHHHCCCCCEEHHHCCCCCCCEEEEEEECCCCHHHHHH
LPRGRQPITTTAVFTREKPGWLARGWERIAEEVAAGRQAYVVASRIDADDKDSGPEEAEE
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHH
KRPPPVPVTELYETIRGSLLPGLRIGLLHGRLPSEQKDAVMTAFNAGEIDVLVCTTVIEV
CCCCCCCHHHHHHHHHHHCCCCHHEEHHHCCCCCCHHCCEEEEECCCCEEEHHHHHHHHH
GVDVPNATVMLIMDADRFGISQLHQLRGRVGRGGNKGLCLLVSPCSPAGSAGRRLRAVQD
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
TLDGFTLAELDLEERREGDVLGRDQSGRAVNLRLLSLLDHRDMIETAREMAMRACADDPE
HHCCCEEEECCHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LAQQPALAGMARRFLVADQIEYLDKS
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKLSDRLDHVLGNKASDVLDAEFGLITVEDLLHHYPRRYSTDFSLRDEQDGESAKPGEH
CCHHHHHHHHHCCCHHHHHHCCCCEEEHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCC
TTLVGFITSAELKRMRNRKGQFLSVTLGSAPHAVQATFFHPHKVKRDLQVGNRVMLSGAV
EEEEEEHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECHHHHHHHHHHCCEEEEECCH
GEFRGKPQLTHPDYLVLETALGESTETRGSTALRGIAGAARDASTAISAFQRNVFPIYPA
HHCCCCCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCEEECCC
TKNLESWDIYRCIDQVLTQLDPVPEALPDAVLAEYGLMSLDEALRKIHMSEDASEQKQAR
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RRLAFDEALGLQLALAMRRGSEIGSAGPPMPLAQAGLRADLLGQLPFDLTEGQRHVVAEI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHCCCCCCCCCCHHHHHHH
GEDLAGVKPMNRLLQGEVGSGKTVVALLAMMQAIDAGYQCALLAPTEVLAVQHARSLRAM
HHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
LGSLATAGELGAPDDATSIALLTGSMSPAVKKQIKADVATGLAGIVIGTHALLQDSVDFH
HHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
NLGLVVVDEQHRFGVEQRDRLRAKASQGIVPHLLVMTATPIPRTVALTVFGDLETSTLRE
HCCEEEECCHHHCCCCHHHHHHHHHHCCCCCEEHHHCCCCCCCEEEEEEECCCCHHHHHH
LPRGRQPITTTAVFTREKPGWLARGWERIAEEVAAGRQAYVVASRIDADDKDSGPEEAEE
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHH
KRPPPVPVTELYETIRGSLLPGLRIGLLHGRLPSEQKDAVMTAFNAGEIDVLVCTTVIEV
CCCCCCCHHHHHHHHHHHCCCCHHEEHHHCCCCCCHHCCEEEEECCCCEEEHHHHHHHHH
GVDVPNATVMLIMDADRFGISQLHQLRGRVGRGGNKGLCLLVSPCSPAGSAGRRLRAVQD
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
TLDGFTLAELDLEERREGDVLGRDQSGRAVNLRLLSLLDHRDMIETAREMAMRACADDPE
HHCCCEEEECCHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LAQQPALAGMARRFLVADQIEYLDKS
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]