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The map label for this gene is ywbI [H]

Identifier: 169630289

GI number: 169630289

Start: 3249871

End: 3250764

Strand: Reverse

Name: ywbI [H]

Synonym: MAB_3208c

Alternate gene names: 169630289

Gene position: 3250764-3249871 (Counterclockwise)

Preceding gene: 169630290

Following gene: 169630287

Centisome position: 64.15

GC content: 63.09

Gene sequence:

>894_bases
ATGGAGTTGAGGCAGCTTGAGTATTTTCTCGCGGTGGCCGAACACGCTAACTTCACACGCGCTGCCGAAGCTCTGCACGT
CGCTCAACCCTGGGTCAGTGCGCAAGTGCGGCGGCTGGAGCGAGAACTGGGCAATGAGCTGTTCGATCGTTCCAGCAGGG
TGCTCAGGCTGACCGAGTTCGGCAAGGCGCTGCTGCCGCTTGCCGGAGCCGCGCTTCGGACGGTGGGTGAAATACGTTCG
GCCGCTGACGCCATGGCGGGAGTGCTGTGCGGCCAGCTTGCGATCGGTACGGTGCCACACCCGTCACCCCTGCTGGCTGA
GGCACTGGCGGCCTACCGCAGGGCGCACCCGGCGGTGACAGTGACGTTGACCGAGGCCAGGTCTGACCAGTTGGCCACAG
CGGTCGTGGAACGTCGGCTGGATATGGCAGTAATGGCATGGCTGGCTCAGCCGCCGTCTCAACTGCGCGAACGGATCTTG
GCCAAGGAAAATATCGTGGCGGTGGTCCATCGCGATGACCCCTTGGCGGGGCGCGAGTCGGTCGCGCTGGCAGAGTTGCG
CGATCGCGCGCTGATAAGTCACCCGCAGGGATGCGAGATACGGACAGCGCTCGATCAGGCCTGTCTGGCAACAGGATTTA
CGCCGCGCGTTGTCTTTGAGACAAGCTCGGCCGACATGATGAGACATCTCGTGGTGAGAGATCTGGGTGTAGCGGTGACC
CCCAGATTGCCACGCGAACAGCTGGGCAGGCTCCGGCAGATCGATCTTTCCGATAGGGCGATGAGTGGGCGGCTGTCTCT
GTTGTGGAGGGGAAAAGGGGCCACTCTCGAGGCGGTGGCCTTTGCGGCGTGCATTGACGAATTGTGCCGGAAGGACGCCA
ATCTCGTGTCGTGA

Upstream 100 bases:

>100_bases
GCGCTGGGGGTGGCCAAATTCGGGCCCTTCTGGACCGTCAACTACTGACCGTTGGGTTGGTCGCGGCGGTAGGGTTCTAT
GGGGGCGCTGGTGATTCATC

Downstream 100 bases:

>100_bases
CGGCTGTGACGGTCCAGGTTGGCGGATCGGTCAGCCGTACCACTCGAACGCGACGAACACCGCCAGCACGATCAGCACGA
TCAGCACGATATTGACGCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MELRQLEYFLAVAEHANFTRAAEALHVAQPWVSAQVRRLERELGNELFDRSSRVLRLTEFGKALLPLAGAALRTVGEIRS
AADAMAGVLCGQLAIGTVPHPSPLLAEALAAYRRAHPAVTVTLTEARSDQLATAVVERRLDMAVMAWLAQPPSQLRERIL
AKENIVAVVHRDDPLAGRESVALAELRDRALISHPQGCEIRTALDQACLATGFTPRVVFETSSADMMRHLVVRDLGVAVT
PRLPREQLGRLRQIDLSDRAMSGRLSLLWRGKGATLEAVAFAACIDELCRKDANLVS

Sequences:

>Translated_297_residues
MELRQLEYFLAVAEHANFTRAAEALHVAQPWVSAQVRRLERELGNELFDRSSRVLRLTEFGKALLPLAGAALRTVGEIRS
AADAMAGVLCGQLAIGTVPHPSPLLAEALAAYRRAHPAVTVTLTEARSDQLATAVVERRLDMAVMAWLAQPPSQLRERIL
AKENIVAVVHRDDPLAGRESVALAELRDRALISHPQGCEIRTALDQACLATGFTPRVVFETSSADMMRHLVVRDLGVAVT
PRLPREQLGRLRQIDLSDRAMSGRLSLLWRGKGATLEAVAFAACIDELCRKDANLVS
>Mature_297_residues
MELRQLEYFLAVAEHANFTRAAEALHVAQPWVSAQVRRLERELGNELFDRSSRVLRLTEFGKALLPLAGAALRTVGEIRS
AADAMAGVLCGQLAIGTVPHPSPLLAEALAAYRRAHPAVTVTLTEARSDQLATAVVERRLDMAVMAWLAQPPSQLRERIL
AKENIVAVVHRDDPLAGRESVALAELRDRALISHPQGCEIRTALDQACLATGFTPRVVFETSSADMMRHLVVRDLGVAVT
PRLPREQLGRLRQIDLSDRAMSGRLSLLWRGKGATLEAVAFAACIDELCRKDANLVS

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=280, Percent_Identity=33.5714285714286, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790399, Length=244, Percent_Identity=31.9672131147541, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787530, Length=242, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787879, Length=277, Percent_Identity=29.6028880866426, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788297, Length=243, Percent_Identity=30.8641975308642, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI2367136, Length=240, Percent_Identity=27.0833333333333, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788296, Length=242, Percent_Identity=28.099173553719, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=31.5573770491803, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=35.1724137931034, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787806, Length=298, Percent_Identity=26.8456375838926, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI145693105, Length=244, Percent_Identity=24.1803278688525, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788481, Length=244, Percent_Identity=28.2786885245902, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789204, Length=240, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787589, Length=144, Percent_Identity=34.0277777777778, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=242, Percent_Identity=23.5537190082645, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32500; Mature: 32500

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQLEYFLAVAEHANFTRAAEALHVAQPWVSAQVRRLERELGNELFDRSSRVLRLTEF
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEHHHH
GKALLPLAGAALRTVGEIRSAADAMAGVLCGQLAIGTVPHPSPLLAEALAAYRRAHPAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEE
VTLTEARSDQLATAVVERRLDMAVMAWLAQPPSQLRERILAKENIVAVVHRDDPLAGRES
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEECCCCCCCCHH
VALAELRDRALISHPQGCEIRTALDQACLATGFTPRVVFETSSADMMRHLVVRDLGVAVT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCC
PRLPREQLGRLRQIDLSDRAMSGRLSLLWRGKGATLEAVAFAACIDELCRKDANLVS
CCCCHHHHCHHHCCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MELRQLEYFLAVAEHANFTRAAEALHVAQPWVSAQVRRLERELGNELFDRSSRVLRLTEF
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEHHHH
GKALLPLAGAALRTVGEIRSAADAMAGVLCGQLAIGTVPHPSPLLAEALAAYRRAHPAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEE
VTLTEARSDQLATAVVERRLDMAVMAWLAQPPSQLRERILAKENIVAVVHRDDPLAGRES
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEEECCCCCCCCHH
VALAELRDRALISHPQGCEIRTALDQACLATGFTPRVVFETSSADMMRHLVVRDLGVAVT
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCC
PRLPREQLGRLRQIDLSDRAMSGRLSLLWRGKGATLEAVAFAACIDELCRKDANLVS
CCCCHHHHCHHHCCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]