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The map label for this gene is dmsA [H]

Identifier: 169630124

GI number: 169630124

Start: 3092259

End: 3094583

Strand: Direct

Name: dmsA [H]

Synonym: MAB_3041

Alternate gene names: 169630124

Gene position: 3092259-3094583 (Clockwise)

Preceding gene: 169630121

Following gene: 169630129

Centisome position: 61.03

GC content: 66.62

Gene sequence:

>2325_bases
GTGATCAGGCCCGCGTTTTCCGCTGTTCAGGTGAGTGGCTCGGCACGGCTTTCCCACACCCACTGGGGCGCGTTCACCCC
CGAGGTCCGGGACGGCGAAGTGATCGGCGTCACTCCGATCGAGACCGATCTAGACCCCTCCCCGCTGCTGCAGAACATTC
CTGGTTCCATCCGGCACCAGGCCCGGGTGACCGCGCCGGCGGTGCGCAGCGGCTGGCTGCGGGAGGGCCCTGGCCCCAGC
GACAAGCGTGGCGCCGACGAATACGTCGAGGTGTCCTGGGATGAGCTGACCGAACTGCTGGCCGATGAACTGCGGCGCGT
CGTCGACACCCATGGCAACGAGGCTATCTACGGGGGCTCATACGGCTGGGCCAGCGCAGGGCGCTTCCACCACGCCCAGA
GTCAGGTGCACAGGTTCCTGAAACTGCTGGGCGGGTATACCTTTTCGCGTCATTCCTATAGCCTCGGCGCGACCGGCGTC
ATCATGCCGCACGTCATCGGAACCCACGACGGGCTGTTCAAGCGATCCACATCCTGGGACGTGATCGTCGAAAACACCGA
TCTGCTGATCGCGTTCGGCGGAATCGCGCTGAAGAACACGGGTGTCAACCATGGCGGCACCACCGCGCACCCGGCGCGCG
ATGCCCTCAACAGATTCCGCGACCGCGGTGGACGCATCGTCTCCTTTAGTCCGCTACACGATGACATCGACGGCGAATGC
GAATGGCACGCCCCGATTCCCGGGACCGACGTGGCGGTCATGCTGGCGCTGGCGCATGTGCTGGCGGTGGAGAAGCTCGC
AGATCTGACCTTCTTGAGCAGCTACTGCACCGGCTACGAGCGGTTCGAGCGCTATCTACTGGGCGTCGACGACGGCGTAC
CCAAGAGCCCGGAGTGGGCGGCACCCATCAGTGGCCTGGACGCGGCCGAGCTGCGCACCTTGGCCCGCCGCATGGCGGCA
GGGCGCACTCTGGTGACGGTCAGCTGGTCCCTGCAACGGGTGCGCCATGGTGAGCAGGCACCCTGGATGGGACTCACCCT
GGCCGCGATGCTCGGTCAGATCGGGCTTCCGGGAGGCGGTTTCGGCCATGGCTACGGCTCGATGAACGAGCCCGGGCTGG
CCCCGGTGAGCTGTCCGCTGCCCACCTTTCCGCAGGGCCCCAACCCCGTCGAGACGTTCATCCCGGTGGCGGCCATCAGC
GAGCTCCTGCTGCGCCCTGGGCAGACGCTCGCCTACAACGGTCAAACACTGACCTTGCCGGACATCCGCTGCGTCTATTG
GGCGGGCGGCAACCCCTTCCATCATCATCAGAATCTGCCCAGACTGCGCCGCGCGCTGTCCCGGGTCGACACCGTCGTCG
TGCACGACCCGGTGTGGACCGCGATGGCCAAGCACGCCGACATCGTCGTGCCGTCCACCACCAGTCTGGAGCGCGATGAC
TTCTCCGGTAGCCGCAACGACCCACTGCTGGTGGCGATGAAAGCCGTCGCACCGCCCTATGCCAACTCCCGTGACGACTA
CACCACGTTCTCGGCACTCGCCGACAGACTCGGATTCGGCGAGCAGTTCAGCGAGGGACGCACCGCCGCCCAGTGGCTGC
GCCACATCTACACCGAGTGGGCCGGCGCGCTGAACTTTTCGGTGCCCTCCTTCGACGAATTCTGGGACCGCGGCTATCTG
GAGTTGCCGACCGATGCCGGCCTGACGCTGCTGTCGGACTTCCGTGAGAACCCCGCTGCGCACCCGTTGCACACTCCCAG
CGGGCGCATCGAAATCTTTTCCGAGACCATCGACGGCTTCGGATACTCCGACTGCGGTGGTCACCCACAGTGGTACGAAC
CCACCGAATGGCTGGGCGGTGAGCGCGCTCAGCGTTTTCCGTTGCATCTGATCGCCAATCAGCCGCGCACCAGGCTGCAC
AGCCAGCTCGACTTCGGTGGCACCAGCCAAGGGTCGAAGGTGCGGGGACGCGAGCCTCTCCGGATACATCCGCAGGACGC
CGCCACCCGTGGTATCGCCGACGGCGACGTGGTGCGGGTGTTCAACGACCGCGGCGCCTGCCTGGCCGGGGCGGTCCTCG
ATGAGGGCCTACGACGCCAGGTGGTGCAGCTGTCGACCGGGGCATGGTTTGACCCGATCGAGCCCGCCGACCCGAATTCT
GCTTGCGCCCATGGCAATCCGAATGTGCTGACAGACGACTCGGGAACCTCGTCGCTGGCGCAGGGCTGCACCGGGCAGCA
CGTGCTGGTGCAGATCGAACGGTTCGAGGGGACGCCACCGCCGGTGCGGGCACACACCCCGCCGCGGTTCGTCGCCCGCG
ACTAG

Upstream 100 bases:

>100_bases
CGGTTTGGATTTACGTACTTGGCAGAATGTATACCAACCCACTGGTCGGTCGGTACTCGCCTGCCCGGTTTCGTCGGACA
GAAAGCCTAGAGTCATTCAG

Downstream 100 bases:

>100_bases
AGCGCGGTCAGGACGGCGGCAAGCGCCCGCGGCACCCGCCCCACTACCCGCGTGCCATCGGCGAGATGCTCGGTGGACTG
CACCTGCCCCTCGGTGTGGA

Product: putative biotin sulfoxide reductase BisC

Products: Biotin [C]

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 774; Mature: 774

Protein sequence:

>774_residues
MIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDPSPLLQNIPGSIRHQARVTAPAVRSGWLREGPGPS
DKRGADEYVEVSWDELTELLADELRRVVDTHGNEAIYGGSYGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGV
IMPHVIGTHDGLFKRSTSWDVIVENTDLLIAFGGIALKNTGVNHGGTTAHPARDALNRFRDRGGRIVSFSPLHDDIDGEC
EWHAPIPGTDVAVMLALAHVLAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPKSPEWAAPISGLDAAELRTLARRMAA
GRTLVTVSWSLQRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEPGLAPVSCPLPTFPQGPNPVETFIPVAAIS
ELLLRPGQTLAYNGQTLTLPDIRCVYWAGGNPFHHHQNLPRLRRALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDD
FSGSRNDPLLVAMKAVAPPYANSRDDYTTFSALADRLGFGEQFSEGRTAAQWLRHIYTEWAGALNFSVPSFDEFWDRGYL
ELPTDAGLTLLSDFRENPAAHPLHTPSGRIEIFSETIDGFGYSDCGGHPQWYEPTEWLGGERAQRFPLHLIANQPRTRLH
SQLDFGGTSQGSKVRGREPLRIHPQDAATRGIADGDVVRVFNDRGACLAGAVLDEGLRRQVVQLSTGAWFDPIEPADPNS
ACAHGNPNVLTDDSGTSSLAQGCTGQHVLVQIERFEGTPPPVRAHTPPRFVARD

Sequences:

>Translated_774_residues
MIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDPSPLLQNIPGSIRHQARVTAPAVRSGWLREGPGPS
DKRGADEYVEVSWDELTELLADELRRVVDTHGNEAIYGGSYGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGV
IMPHVIGTHDGLFKRSTSWDVIVENTDLLIAFGGIALKNTGVNHGGTTAHPARDALNRFRDRGGRIVSFSPLHDDIDGEC
EWHAPIPGTDVAVMLALAHVLAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPKSPEWAAPISGLDAAELRTLARRMAA
GRTLVTVSWSLQRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEPGLAPVSCPLPTFPQGPNPVETFIPVAAIS
ELLLRPGQTLAYNGQTLTLPDIRCVYWAGGNPFHHHQNLPRLRRALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDD
FSGSRNDPLLVAMKAVAPPYANSRDDYTTFSALADRLGFGEQFSEGRTAAQWLRHIYTEWAGALNFSVPSFDEFWDRGYL
ELPTDAGLTLLSDFRENPAAHPLHTPSGRIEIFSETIDGFGYSDCGGHPQWYEPTEWLGGERAQRFPLHLIANQPRTRLH
SQLDFGGTSQGSKVRGREPLRIHPQDAATRGIADGDVVRVFNDRGACLAGAVLDEGLRRQVVQLSTGAWFDPIEPADPNS
ACAHGNPNVLTDDSGTSSLAQGCTGQHVLVQIERFEGTPPPVRAHTPPRFVARD
>Mature_774_residues
MIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDPSPLLQNIPGSIRHQARVTAPAVRSGWLREGPGPS
DKRGADEYVEVSWDELTELLADELRRVVDTHGNEAIYGGSYGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGV
IMPHVIGTHDGLFKRSTSWDVIVENTDLLIAFGGIALKNTGVNHGGTTAHPARDALNRFRDRGGRIVSFSPLHDDIDGEC
EWHAPIPGTDVAVMLALAHVLAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPKSPEWAAPISGLDAAELRTLARRMAA
GRTLVTVSWSLQRVRHGEQAPWMGLTLAAMLGQIGLPGGGFGHGYGSMNEPGLAPVSCPLPTFPQGPNPVETFIPVAAIS
ELLLRPGQTLAYNGQTLTLPDIRCVYWAGGNPFHHHQNLPRLRRALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDD
FSGSRNDPLLVAMKAVAPPYANSRDDYTTFSALADRLGFGEQFSEGRTAAQWLRHIYTEWAGALNFSVPSFDEFWDRGYL
ELPTDAGLTLLSDFRENPAAHPLHTPSGRIEIFSETIDGFGYSDCGGHPQWYEPTEWLGGERAQRFPLHLIANQPRTRLH
SQLDFGGTSQGSKVRGREPLRIHPQDAATRGIADGDVVRVFNDRGACLAGAVLDEGLRRQVVQLSTGAWFDPIEPADPNS
ACAHGNPNVLTDDSGTSSLAQGCTGQHVLVQIERFEGTPPPVRAHTPPRFVARD

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=785, Percent_Identity=38.2165605095541, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1787231, Length=790, Percent_Identity=39.1139240506329, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI145693196, Length=773, Percent_Identity=39.1979301423027, Blast_Score=522, Evalue=1e-149,
Organism=Escherichia coli, GI87081797, Length=712, Percent_Identity=30.3370786516854, Blast_Score=262, Evalue=5e-71,
Organism=Escherichia coli, GI1787870, Length=815, Percent_Identity=28.5889570552147, Blast_Score=241, Evalue=2e-64,
Organism=Escherichia coli, GI171474008, Length=750, Percent_Identity=27.8666666666667, Blast_Score=225, Evalue=1e-59,
Organism=Escherichia coli, GI3868721, Length=639, Percent_Identity=21.9092331768388, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 84340; Mature: 84340

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDPSPLLQNIPGSIRHQ
CCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCHHHHHH
ARVTAPAVRSGWLREGPGPSDKRGADEYVEVSWDELTELLADELRRVVDTHGNEAIYGGS
HHCCCHHHHCCCCCCCCCCCCCCCCCHHEECCHHHHHHHHHHHHHHHHHCCCCCEEECCC
YGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGVIMPHVIGTHDGLFKRSTSWD
CCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEECCCEECCCCCCEECCCCCE
VIVENTDLLIAFGGIALKNTGVNHGGTTAHPARDALNRFRDRGGRIVSFSPLHDDIDGEC
EEEECCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCE
EWHAPIPGTDVAVMLALAHVLAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPKSPEWA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
APISGLDAAELRTLARRMAAGRTLVTVSWSLQRVRHGEQAPWMGLTLAAMLGQIGLPGGG
CCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
FGHGYGSMNEPGLAPVSCPLPTFPQGPNPVETFIPVAAISELLLRPGQTLAYNGQTLTLP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEECC
DIRCVYWAGGNPFHHHQNLPRLRRALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDD
CEEEEEECCCCCCHHCCCCHHHHHHHHHHCEEEEECCHHHHHHCCCCEEECCCCCCCCCC
FSGSRNDPLLVAMKAVAPPYANSRDDYTTFSALADRLGFGEQFSEGRTAAQWLRHIYTEW
CCCCCCCCEEEEEEHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHH
AGALNFSVPSFDEFWDRGYLELPTDAGLTLLSDFRENPAAHPLHTPSGRIEIFSETIDGF
HCCEECCCCCHHHHHCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHCCC
GYSDCGGHPQWYEPTEWLGGERAQRFPLHLIANQPRTRLHSQLDFGGTSQGSKVRGREPL
CCCCCCCCCCCCCCHHHCCCCCHHHCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCC
RIHPQDAATRGIADGDVVRVFNDRGACLAGAVLDEGLRRQVVQLSTGAWFDPIEPADPNS
EECCCHHHHCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ACAHGNPNVLTDDSGTSSLAQGCTGQHVLVQIERFEGTPPPVRAHTPPRFVARD
CCCCCCCCEEECCCCCHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRPAFSAVQVSGSARLSHTHWGAFTPEVRDGEVIGVTPIETDLDPSPLLQNIPGSIRHQ
CCCCCCCEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCHHHHHH
ARVTAPAVRSGWLREGPGPSDKRGADEYVEVSWDELTELLADELRRVVDTHGNEAIYGGS
HHCCCHHHHCCCCCCCCCCCCCCCCCHHEECCHHHHHHHHHHHHHHHHHCCCCCEEECCC
YGWASAGRFHHAQSQVHRFLKLLGGYTFSRHSYSLGATGVIMPHVIGTHDGLFKRSTSWD
CCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCEECCCEECCCCCCEECCCCCE
VIVENTDLLIAFGGIALKNTGVNHGGTTAHPARDALNRFRDRGGRIVSFSPLHDDIDGEC
EEEECCCEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCE
EWHAPIPGTDVAVMLALAHVLAVEKLADLTFLSSYCTGYERFERYLLGVDDGVPKSPEWA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
APISGLDAAELRTLARRMAAGRTLVTVSWSLQRVRHGEQAPWMGLTLAAMLGQIGLPGGG
CCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
FGHGYGSMNEPGLAPVSCPLPTFPQGPNPVETFIPVAAISELLLRPGQTLAYNGQTLTLP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEECC
DIRCVYWAGGNPFHHHQNLPRLRRALSRVDTVVVHDPVWTAMAKHADIVVPSTTSLERDD
CEEEEEECCCCCCHHCCCCHHHHHHHHHHCEEEEECCHHHHHHCCCCEEECCCCCCCCCC
FSGSRNDPLLVAMKAVAPPYANSRDDYTTFSALADRLGFGEQFSEGRTAAQWLRHIYTEW
CCCCCCCCEEEEEEHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHH
AGALNFSVPSFDEFWDRGYLELPTDAGLTLLSDFRENPAAHPLHTPSGRIEIFSETIDGF
HCCEECCCCCHHHHHCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHCCC
GYSDCGGHPQWYEPTEWLGGERAQRFPLHLIANQPRTRLHSQLDFGGTSQGSKVRGREPL
CCCCCCCCCCCCCCHHHCCCCCHHHCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCC
RIHPQDAATRGIADGDVVRVFNDRGACLAGAVLDEGLRRQVVQLSTGAWFDPIEPADPNS
EECCCHHHHCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
ACAHGNPNVLTDDSGTSSLAQGCTGQHVLVQIERFEGTPPPVRAHTPPRFVARD
CCCCCCCCEEECCCCCHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]