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The map label for this gene is mmgC [H]

Identifier: 169630123

GI number: 169630123

Start: 3090994

End: 3092148

Strand: Reverse

Name: mmgC [H]

Synonym: MAB_3040c

Alternate gene names: 169630123

Gene position: 3092148-3090994 (Counterclockwise)

Preceding gene: 169630125

Following gene: 169630122

Centisome position: 61.02

GC content: 61.3

Gene sequence:

>1155_bases
ATGGCCGGCGCCGTTAAGTTCAAACGCACCATTTTCGAACCCGAGCACGAACTGTTCCGCGAGTCGTTCAAGACCTTCCT
GGATCGGCACGCTGAGCCGTACAAGGAGGAGTGGGAGAAGAACAAGATCGTCGACCGTGCACTGTGGGTCGAGGCCGGCA
AACAGGGCTTCCTGGGCACCGACATGCCCGAGGAGTTCGGTGGCGGTGGTCTTATCGATTTCCGCTACAACACGATCATC
ACCGAAGAGGTGACCAAGGGACGCCACACCGGCGTCGGATTCAGCCTGCATAACGATGTCGCCGGCCCGTACTTCCGGGA
CCTGGCCAATGACGAGCAGAAGGCCCGCTGGTTCCCCGGCTTCTGTTCCGGCGAGCTGATTTCGGCCATCGCCATGACCG
AGCCCGGCACCGGAAGCGATCTGCAGGGCATCAAGACCCGCGCCGTCAAGGACGGCGATCATTACATTCTCAATGGCGCA
AAGACCTTCATCACCAACGGCATCAACGCCGACCTGGTGATCGTGGTCGCACAGACCGATCCGGAAAAGGGCGCGCTGGG
TTTCTCGCTGATCGTTGTGGAGCGCGGCATGGAGGGCTTCGAACGCGGCCGCAAGCTCGACAAGGTCGGTCTGGATGCTC
AGGACACCGCCGAACTGTCCTTCACCGACGTCCGGGTGCCTGCGGCCAACCTGCTGGGTGAAGAGGGTCAGGGCTTCATC
TACCTGATGAAGAACCTGCCGCAGGAGCGTATGTCGATCGCCGTCATGGCGGCCGCCGCGATGGAGTCGGTGCTCGAAGA
GACCATTGCGTACACGACCGAGCGCAAGGCATTCGGCAAGCCCATCAAGAGCTTCCAGAACAGTCGTTTCCTGCTCGCCG
AGCTGGCCACCGACGCAACGGTCATCCGGGTCATGGTCGACGAGTTCATCTCGTTGCTCAACAAAGAAGAGCTGAGTGTC
GAGCAGGCCGCGATGGCCAAGTGGTACAGCACCGAGAAGCAGGTCCACCTGATCGACCGCTGCCTGCAGCTGCACGGCGG
GTACGGCTTCATGCGCGAGTACCCGGTGGCCCGGGCATACATGGACTCCCGTATCCAGACGATCTACGGCGGCACTACCG
AGATCATGAAGGAGATCATCGGGCGTTCGCTCTAG

Upstream 100 bases:

>100_bases
CTAGGCTTTCTGTCCGACGAAACCGGGCAGGCGAGTACCGACCGACCAGTGGGTTGGTATACATTCTGCCAAGTACGTAA
ATCCAAACCGGAAGGTGATC

Downstream 100 bases:

>100_bases
TCGCCCATGCACATTCGTGACGCGACGGCCGCCGATGCGGCCGCGTGTGCGGCAATCTATGCGCCGTATGTGACCGATAC
GGCCATCTCGTTTGAGGAGG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRALWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTII
TEEVTKGRHTGVGFSLHNDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIKTRAVKDGDHYILNGA
KTFITNGINADLVIVVAQTDPEKGALGFSLIVVERGMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFI
YLMKNLPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAELATDATVIRVMVDEFISLLNKEELSV
EQAAMAKWYSTEKQVHLIDRCLQLHGGYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL

Sequences:

>Translated_384_residues
MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRALWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTII
TEEVTKGRHTGVGFSLHNDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIKTRAVKDGDHYILNGA
KTFITNGINADLVIVVAQTDPEKGALGFSLIVVERGMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFI
YLMKNLPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAELATDATVIRVMVDEFISLLNKEELSV
EQAAMAKWYSTEKQVHLIDRCLQLHGGYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL
>Mature_383_residues
AGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRALWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTIIT
EEVTKGRHTGVGFSLHNDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIKTRAVKDGDHYILNGAK
TFITNGINADLVIVVAQTDPEKGALGFSLIVVERGMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFIY
LMKNLPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAELATDATVIRVMVDEFISLLNKEELSVE
QAAMAKWYSTEKQVHLIDRCLQLHGGYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=49.868073878628, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=33.6, Blast_Score=228, Evalue=9e-60,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=34.2318059299191, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=34.7058823529412, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI4557233, Length=382, Percent_Identity=34.0314136125654, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=30.7486631016043, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=32.8, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=32.8, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=32.4675324675325, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=32.4675324675325, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI21361497, Length=335, Percent_Identity=33.4328358208955, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI4503943, Length=373, Percent_Identity=27.8820375335121, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI7669494, Length=351, Percent_Identity=27.6353276353276, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38505218, Length=281, Percent_Identity=25.9786476868327, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI211971008, Length=284, Percent_Identity=26.7605633802817, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI48976061, Length=284, Percent_Identity=26.7605633802817, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI218563752, Length=310, Percent_Identity=26.1290322580645, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081958, Length=376, Percent_Identity=29.2553191489362, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1786223, Length=374, Percent_Identity=24.331550802139, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082384, Length=282, Percent_Identity=25.177304964539, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=34.8837209302326, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17538396, Length=369, Percent_Identity=32.520325203252, Blast_Score=214, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=32.6259946949602, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17534899, Length=386, Percent_Identity=32.1243523316062, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=351, Percent_Identity=30.1994301994302, Blast_Score=190, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=29.5392953929539, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=387, Percent_Identity=30.749354005168, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17551932, Length=381, Percent_Identity=30.7086614173228, Blast_Score=180, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=30.2387267904509, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71985184, Length=348, Percent_Identity=31.8965517241379, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=31.6725978647687, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71982178, Length=266, Percent_Identity=30.8270676691729, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=32.3144104803493, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=263, Percent_Identity=32.6996197718631, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17534353, Length=364, Percent_Identity=27.7472527472527, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=29.2887029288703, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17562446, Length=286, Percent_Identity=29.020979020979, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI86563381, Length=267, Percent_Identity=26.9662921348315, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=267, Percent_Identity=26.9662921348315, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=32.6145552560647, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=32.6315789473684, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=30.8510638297872, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24660351, Length=370, Percent_Identity=32.1621621621622, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=28.3783783783784, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI281363737, Length=344, Percent_Identity=31.3953488372093, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19920834, Length=376, Percent_Identity=28.4574468085106, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42899; Mature: 42768

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRALWVEAGKQGFLGT
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DMPEEFGGGGLIDFRYNTIITEEVTKGRHTGVGFSLHNDVAGPYFRDLANDEQKARWFPG
CCCHHHCCCCEEEEEECEEEHHHHHCCCCCCCCEEECCCCCCHHHHHHCCCCHHHCCCCC
FCSGELISAIAMTEPGTGSDLQGIKTRAVKDGDHYILNGAKTFITNGINADLVIVVAQTD
CCCHHHHHHHHCCCCCCCCCCCHHHHHHEECCCEEEECCHHHHHCCCCCCCEEEEEEECC
PEKGALGFSLIVVERGMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFI
CCCCCCCEEEEEEHHCHHHHHHCCHHHHCCCCCCCCCCEEEEEEECCHHHHCCCCCCCEE
YLMKNLPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAELATDAT
EEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHCCHH
VIRVMVDEFISLLNKEELSVEQAAMAKWYSTEKQVHLIDRCLQLHGGYGFMREYPVARAY
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCHHHHHH
MDSRIQTIYGGTTEIMKEIIGRSL
HHHHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
AGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRALWVEAGKQGFLGT
CCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DMPEEFGGGGLIDFRYNTIITEEVTKGRHTGVGFSLHNDVAGPYFRDLANDEQKARWFPG
CCCHHHCCCCEEEEEECEEEHHHHHCCCCCCCCEEECCCCCCHHHHHHCCCCHHHCCCCC
FCSGELISAIAMTEPGTGSDLQGIKTRAVKDGDHYILNGAKTFITNGINADLVIVVAQTD
CCCHHHHHHHHCCCCCCCCCCCHHHHHHEECCCEEEECCHHHHHCCCCCCCEEEEEEECC
PEKGALGFSLIVVERGMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFI
CCCCCCCEEEEEEHHCHHHHHHCCHHHHCCCCCCCCCCEEEEEEECCHHHHCCCCCCCEE
YLMKNLPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAELATDAT
EEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHCCHH
VIRVMVDEFISLLNKEELSVEQAAMAKWYSTEKQVHLIDRCLQLHGGYGFMREYPVARAY
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHCHHHHHH
MDSRIQTIYGGTTEIMKEIIGRSL
HHHHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]