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The map label for this gene is pimA [H]

Identifier: 169629978

GI number: 169629978

Start: 2946070

End: 2947197

Strand: Reverse

Name: pimA [H]

Synonym: MAB_2894c

Alternate gene names: 169629978

Gene position: 2947197-2946070 (Counterclockwise)

Preceding gene: 169629979

Following gene: 169629977

Centisome position: 58.16

GC content: 65.87

Gene sequence:

>1128_bases
ATGCGCATCGGGATGGTCTGCCCGTACTCCTTTGACGTACCGGGTGGCGTCCAGTCCCATGTCGTGCAGCTGGCAGAGGT
CATGCGTGATCGCGGCCACCACGTGAGCCTGCTTGCGCCGTCGTCGTCGGATCTGGAGCTGCCCGAGTTCGTGGTCTCCG
GCGGCAAGGCCGTTCCGATCCCGTACAACGGATCGGTGGCGCGGCTTCGATTCGGCCCGGCTACCTATGCCAAGACCAGG
CGCTGGCTTGTCGACGGCGACTTTGACGTTCTGCACCTGCATGAACCGAACGCGCCGAGCCTGTCGATGCTGGCGCTCAT
GGTGGCAGAGGGGCCGATTGTCGCGACGTTCCACACGTCCACCACCAAGTCGTTGACGCTCAGCGTGTTTCAAGCCGTGC
TACGTCCCTGGCACGAGAAGATCGTGGGCCGGATAGCGGTCTCGGAGCTGGCCCGGCGCTGGCAGATGGAGGCGCTGGGA
TCCGACGCGGTGGAGATCCCCAATGGTGTCGACGTTCGCTCCTTCTCGGGCGCGCCCGTTCTTGAGGGGTACCCACGCGA
AGGTAAAACGGTGCTGTTCCTGGGGCGCTACGACGAGCCGCGCAAGGGCATGGACGTGCTGATGGGCGCACTGCCGAAGA
TCGCGACCAGCTTTCCCGATGTGGAGATCTTGATCGTGGGGCGCGGCGACGAAGCCGAATTGCGCACGCAGGCGGGACCG
CTGGCTAAGCATCTGAAGTTTCTGGGACAGGTCGACGACGCCACCAAGGCTTCGGCCATGCGCAGCGCCGACGTCTACTG
TGCGCCCAATATCGGCGGCGAGAGCTTCGGCATTGTCTTGGTGGAGGCGATGGCGGCGGGCACGGCCGTCGTCGCCAGCT
CGCTGGATGCCTTCCGCCGGGTGCTTCTGGACGGCACTGCGGGCCGGCTGACACCCACCGGCGATCCCGATGCCTTGGCG
GCGGCCCTCATCGATGTGCTGGGTAATGACGAAGGCCGGGCACAGCTGGTCGCGGCCGGCACCGAGGCGGTGCAGCGGTA
CGACTGGTCGGTGGTCGCCCAGCAGATCATGCTCGTCTATGAGACCGTCACCGCCTCTGGCGCGCGGGTGAAGGTGGACA
GTTGGTGA

Upstream 100 bases:

>100_bases
TCGACGATTTGTCCGAGGAGCGCCGCTCCAAACTGCGGACGGCGCCGCCGCAGGAGCCTGCGGCCTCCCGGGAGACCGAT
CCCGTTGGTGGGCAGGCGTA

Downstream 100 bases:

>100_bases
CGTTCTCGGCGTTGACGGTCGTCGTCATCGCCATCATCGCCCTATTGGTCGCGCTCGGCCTGCTCTGGGCCTACCTGGTG
GCCAACCGCCTGGACCGGCT

Product: phosphatidylinositol alpha-mannosyltransferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MRIGMVCPYSFDVPGGVQSHVVQLAEVMRDRGHHVSLLAPSSSDLELPEFVVSGGKAVPIPYNGSVARLRFGPATYAKTR
RWLVDGDFDVLHLHEPNAPSLSMLALMVAEGPIVATFHTSTTKSLTLSVFQAVLRPWHEKIVGRIAVSELARRWQMEALG
SDAVEIPNGVDVRSFSGAPVLEGYPREGKTVLFLGRYDEPRKGMDVLMGALPKIATSFPDVEILIVGRGDEAELRTQAGP
LAKHLKFLGQVDDATKASAMRSADVYCAPNIGGESFGIVLVEAMAAGTAVVASSLDAFRRVLLDGTAGRLTPTGDPDALA
AALIDVLGNDEGRAQLVAAGTEAVQRYDWSVVAQQIMLVYETVTASGARVKVDSW

Sequences:

>Translated_375_residues
MRIGMVCPYSFDVPGGVQSHVVQLAEVMRDRGHHVSLLAPSSSDLELPEFVVSGGKAVPIPYNGSVARLRFGPATYAKTR
RWLVDGDFDVLHLHEPNAPSLSMLALMVAEGPIVATFHTSTTKSLTLSVFQAVLRPWHEKIVGRIAVSELARRWQMEALG
SDAVEIPNGVDVRSFSGAPVLEGYPREGKTVLFLGRYDEPRKGMDVLMGALPKIATSFPDVEILIVGRGDEAELRTQAGP
LAKHLKFLGQVDDATKASAMRSADVYCAPNIGGESFGIVLVEAMAAGTAVVASSLDAFRRVLLDGTAGRLTPTGDPDALA
AALIDVLGNDEGRAQLVAAGTEAVQRYDWSVVAQQIMLVYETVTASGARVKVDSW
>Mature_375_residues
MRIGMVCPYSFDVPGGVQSHVVQLAEVMRDRGHHVSLLAPSSSDLELPEFVVSGGKAVPIPYNGSVARLRFGPATYAKTR
RWLVDGDFDVLHLHEPNAPSLSMLALMVAEGPIVATFHTSTTKSLTLSVFQAVLRPWHEKIVGRIAVSELARRWQMEALG
SDAVEIPNGVDVRSFSGAPVLEGYPREGKTVLFLGRYDEPRKGMDVLMGALPKIATSFPDVEILIVGRGDEAELRTQAGP
LAKHLKFLGQVDDATKASAMRSADVYCAPNIGGESFGIVLVEAMAAGTAVVASSLDAFRRVLLDGTAGRLTPTGDPDALA
AALIDVLGNDEGRAQLVAAGTEAVQRYDWSVVAQQIMLVYETVTASGARVKVDSW

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Contrary to pimB, the mannosyltransferase pim

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI9755344, Length=389, Percent_Identity=22.107969151671, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 40118; Mature: 40118

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGMVCPYSFDVPGGVQSHVVQLAEVMRDRGHHVSLLAPSSSDLELPEFVVSGGKAVPI
CEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCCEEEC
PYNGSVARLRFGPATYAKTRRWLVDGDFDVLHLHEPNAPSLSMLALMVAEGPIVATFHTS
CCCCCEEEEEECCHHHHHCCEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEECC
TTKSLTLSVFQAVLRPWHEKIVGRIAVSELARRWQMEALGSDAVEIPNGVDVRSFSGAPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCC
LEGYPREGKTVLFLGRYDEPRKGMDVLMGALPKIATSFPDVEILIVGRGDEAELRTQAGP
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCH
LAKHLKFLGQVDDATKASAMRSADVYCAPNIGGESFGIVLVEAMAAGTAVVASSLDAFRR
HHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCCHHHHEEEHHHCCHHHHHHHHHHHHH
VLLDGTAGRLTPTGDPDALAAALIDVLGNDEGRAQLVAAGTEAVQRYDWSVVAQQIMLVY
HHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
ETVTASGARVKVDSW
HHHCCCCCEEEECCC
>Mature Secondary Structure
MRIGMVCPYSFDVPGGVQSHVVQLAEVMRDRGHHVSLLAPSSSDLELPEFVVSGGKAVPI
CEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCCEEEC
PYNGSVARLRFGPATYAKTRRWLVDGDFDVLHLHEPNAPSLSMLALMVAEGPIVATFHTS
CCCCCEEEEEECCHHHHHCCEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEEECC
TTKSLTLSVFQAVLRPWHEKIVGRIAVSELARRWQMEALGSDAVEIPNGVDVRSFSGAPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCC
LEGYPREGKTVLFLGRYDEPRKGMDVLMGALPKIATSFPDVEILIVGRGDEAELRTQAGP
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCH
LAKHLKFLGQVDDATKASAMRSADVYCAPNIGGESFGIVLVEAMAAGTAVVASSLDAFRR
HHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCCCHHHHEEEHHHCCHHHHHHHHHHHHH
VLLDGTAGRLTPTGDPDALAAALIDVLGNDEGRAQLVAAGTEAVQRYDWSVVAQQIMLVY
HHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
ETVTASGARVKVDSW
HHHCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12068013 [H]