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The map label for this gene is ribD [H]

Identifier: 169629892

GI number: 169629892

Start: 2856415

End: 2857437

Strand: Reverse

Name: ribD [H]

Synonym: MAB_2808c

Alternate gene names: 169629892

Gene position: 2857437-2856415 (Counterclockwise)

Preceding gene: 169629893

Following gene: 169629889

Centisome position: 56.39

GC content: 67.16

Gene sequence:

>1023_bases
ATGACCAACCCGATCGGCCTCGACGAGGCCATGGATCTGGCGATCCGGGCCGCCGAAGAGGTCAAGGGCAGCACCTATCC
CAATCCGCCTGTCGGTGCGGTCATTCTGGATGCCGCCGGGCAGGTCGCCGGTGTGGGCGGTACTCGTCCACCGGGGCAGG
AACATGCCGAGGTGGTAGCGCTTGCCGGGGCCGGTGCGGCCGCCCGGGGCGGTACCGCCGTGGTCACTCTGGAGCCGTGC
AACCATCAGGGCAGGACCGGTCCGTGTGTGGATGCGCTTGCCGCGGCGGGTGTTTCACGCGTGGTCTATGCCGTCGCCGA
TCCGAATCCGCAGGCCGCGGGGGGAGCGGCGCGTCTACGCACGCTGGGTATCGAGGTGCTTGATGGCCTGGCCTCTGACC
GCGTCTCGGCGGGACCACTGCGGGAGTGGCTACACAAGCAGCGCACTGGACGTCCTCATGTCACCTGGAAATACGGTGCC
AGTGTCGATGGGCGTAGTGCCGCCAATGACGGCACCAGCCAATGGATCACCAGCGAGCAGTCGCGGGCCGATGTACATCG
GCGCCGGGCATTCGCCGATGCCGTCCTGGTGGGAACCGGCACCGTATTCGCCGATGACCCCCAGCTCACCGCGCGTACCC
CGGACAACGAGTTGGTGCCGCATCAGCCACTGCGCGTGGTGGTCGGTATGCGTGAGGTGTCATCGGACGCAAAGGTTTTG
AACGACGACTCGCACACCATGGTGATCCGTACCCATGATCCCGCGGAGGTGCTCGCGGCACTGGGTGACCGCACCGACAT
CATCCTGGAAGGTGGCCCGACACTCGCCGGCGCGTTCCTGCGCGCCGGCTTGGTCGACCGTATCCTGGCCTACCTGGCGC
CGATGCTGCTGGGTGGCAACGTCCCCGCCGTGGAGGACGTGGGCGTTACCACCCTGTCGCGGGCACTGCGTTGGGAGTAC
GACCAGATCGAGCGGATGGGTCCGGACGTACTACTGAGCCTCGTGCCCCGACTTCCGGTGTGA

Upstream 100 bases:

>100_bases
CAGGTTCGGCGGTCTATGGGGCGCAGAACCCCGAAGCGGCGGTGCGGGCGCTGCGCGAGCAAGCCGCCAGGGCAGCAGCA
CATTCGGCCCGTTGATTGAT

Downstream 100 bases:

>100_bases
GCCGACGAATATCGCGATAACCGCCGCGATGACACAGACGACCGCCGTGATCGCGAACATCTCGCTGTACATCTCGCTGT
AGGCGGTGATGCTCCGATTC

Product: bifunctional riboflavin biosynthesis protein RibG

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTNPIGLDEAMDLAIRAAEEVKGSTYPNPPVGAVILDAAGQVAGVGGTRPPGQEHAEVVALAGAGAAARGGTAVVTLEPC
NHQGRTGPCVDALAAAGVSRVVYAVADPNPQAAGGAARLRTLGIEVLDGLASDRVSAGPLREWLHKQRTGRPHVTWKYGA
SVDGRSAANDGTSQWITSEQSRADVHRRRAFADAVLVGTGTVFADDPQLTARTPDNELVPHQPLRVVVGMREVSSDAKVL
NDDSHTMVIRTHDPAEVLAALGDRTDIILEGGPTLAGAFLRAGLVDRILAYLAPMLLGGNVPAVEDVGVTTLSRALRWEY
DQIERMGPDVLLSLVPRLPV

Sequences:

>Translated_340_residues
MTNPIGLDEAMDLAIRAAEEVKGSTYPNPPVGAVILDAAGQVAGVGGTRPPGQEHAEVVALAGAGAAARGGTAVVTLEPC
NHQGRTGPCVDALAAAGVSRVVYAVADPNPQAAGGAARLRTLGIEVLDGLASDRVSAGPLREWLHKQRTGRPHVTWKYGA
SVDGRSAANDGTSQWITSEQSRADVHRRRAFADAVLVGTGTVFADDPQLTARTPDNELVPHQPLRVVVGMREVSSDAKVL
NDDSHTMVIRTHDPAEVLAALGDRTDIILEGGPTLAGAFLRAGLVDRILAYLAPMLLGGNVPAVEDVGVTTLSRALRWEY
DQIERMGPDVLLSLVPRLPV
>Mature_339_residues
TNPIGLDEAMDLAIRAAEEVKGSTYPNPPVGAVILDAAGQVAGVGGTRPPGQEHAEVVALAGAGAAARGGTAVVTLEPCN
HQGRTGPCVDALAAAGVSRVVYAVADPNPQAAGGAARLRTLGIEVLDGLASDRVSAGPLREWLHKQRTGRPHVTWKYGAS
VDGRSAANDGTSQWITSEQSRADVHRRRAFADAVLVGTGTVFADDPQLTARTPDNELVPHQPLRVVVGMREVSSDAKVLN
DDSHTMVIRTHDPAEVLAALGDRTDIILEGGPTLAGAFLRAGLVDRILAYLAPMLLGGNVPAVEDVGVTTLSRALRWEYD
QIERMGPDVLLSLVPRLPV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=364, Percent_Identity=40.3846153846154, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 35538; Mature: 35406

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPIGLDEAMDLAIRAAEEVKGSTYPNPPVGAVILDAAGQVAGVGGTRPPGQEHAEVVA
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCCCEEEE
LAGAGAAARGGTAVVTLEPCNHQGRTGPCVDALAAAGVSRVVYAVADPNPQAAGGAARLR
EECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCHHHEEEEEECCCCCCCCHHHHHH
TLGIEVLDGLASDRVSAGPLREWLHKQRTGRPHVTWKYGASVDGRSAANDGTSQWITSEQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCH
SRADVHRRRAFADAVLVGTGTVFADDPQLTARTPDNELVPHQPLRVVVGMREVSSDAKVL
HHHHHHHHHHHHHEEEEECCEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEE
NDDSHTMVIRTHDPAEVLAALGDRTDIILEGGPTLAGAFLRAGLVDRILAYLAPMLLGGN
CCCCCEEEEEECCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
VPAVEDVGVTTLSRALRWEYDQIERMGPDVLLSLVPRLPV
CCCHHHCCHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure 
TNPIGLDEAMDLAIRAAEEVKGSTYPNPPVGAVILDAAGQVAGVGGTRPPGQEHAEVVA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCEECCCCCCCCCCCCCEEEE
LAGAGAAARGGTAVVTLEPCNHQGRTGPCVDALAAAGVSRVVYAVADPNPQAAGGAARLR
EECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCHHHEEEEEECCCCCCCCHHHHHH
TLGIEVLDGLASDRVSAGPLREWLHKQRTGRPHVTWKYGASVDGRSAANDGTSQWITSEQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCH
SRADVHRRRAFADAVLVGTGTVFADDPQLTARTPDNELVPHQPLRVVVGMREVSSDAKVL
HHHHHHHHHHHHHEEEEECCEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEE
NDDSHTMVIRTHDPAEVLAALGDRTDIILEGGPTLAGAFLRAGLVDRILAYLAPMLLGGN
CCCCCEEEEEECCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
VPAVEDVGVTTLSRALRWEYDQIERMGPDVLLSLVPRLPV
CCCHHHCCHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]