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The map label for this gene is ribE [H]

Identifier: 169629881

GI number: 169629881

Start: 2846629

End: 2847222

Strand: Reverse

Name: ribE [H]

Synonym: MAB_2797c

Alternate gene names: 169629881

Gene position: 2847222-2846629 (Counterclockwise)

Preceding gene: 169629882

Following gene: 169629880

Centisome position: 56.19

GC content: 65.15

Gene sequence:

>594_bases
ATGTTCACAGGAATCGTTGAGGAGCTTGGCGAGATCCTGGGCAGGGAGGACCTCGGGGACTCTGCCCGTCTCACTGTGCT
CGGACCTCTCGTCGTGGAGGACGCGAAACACGGCGACTCGATCGCCGTCAACGGCGTGTGCCTGACGGTGGTCGATGTAC
GCGAGGGGGGCGTCTTCACCACGGACGTGATGGGCGAGACGCTGGCACGGTCCAGTCTGGACAAGATCGAGGCGGGCGCC
AAGGTCAACCTGGAGCGGGCGGCGGCGGTCAACAGCCGGCTCGGCGGGCACATCGTGCAGGGGCATGTCGACGGCACCGG
CAATGTGCTGTCGCGCTCACCGTCGGAGAACTGGGAAGTGGTGCGGGTCTCACTGCCCTCGGCGGTGGCCAGGTATGTGG
TCGAAAAGGGATCGATCACCGTGGACGGGGTGTCCCTGACGGTCTCCGGGCTGGGGCCGGATTGGTTCGAGGTGTCGCTC
ATTCCGACCACGCTGGATCTGACCACGCTGGGCGCCGCGGCGGTGGGAACGACGGTCAATCTCGAGGTGGATGTGATCGC
GAAGTACGTCGAGAGATTGCTTGAGCACCGATGA

Upstream 100 bases:

>100_bases
GATGTGCAGATGGCGTGCGCGGCGGCGGGAACGCGCGCCTGAAACCGATTGCACGATAAGGCGATCAAAAGGGGAGCGGC
GGCGGCGCTAGGCTTGTCGA

Downstream 100 bases:

>100_bases
GCGGCTTGCGCGAAGAGCGCAGACACCGATGAGCGGCTTGCGCGAAGAGCGCAGACACCGATGAGCGGCTTGCGCGAAGA
GCGCAGATAGCGCGGCTCGT

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MFTGIVEELGEILGREDLGDSARLTVLGPLVVEDAKHGDSIAVNGVCLTVVDVREGGVFTTDVMGETLARSSLDKIEAGA
KVNLERAAAVNSRLGGHIVQGHVDGTGNVLSRSPSENWEVVRVSLPSAVARYVVEKGSITVDGVSLTVSGLGPDWFEVSL
IPTTLDLTTLGAAAVGTTVNLEVDVIAKYVERLLEHR

Sequences:

>Translated_197_residues
MFTGIVEELGEILGREDLGDSARLTVLGPLVVEDAKHGDSIAVNGVCLTVVDVREGGVFTTDVMGETLARSSLDKIEAGA
KVNLERAAAVNSRLGGHIVQGHVDGTGNVLSRSPSENWEVVRVSLPSAVARYVVEKGSITVDGVSLTVSGLGPDWFEVSL
IPTTLDLTTLGAAAVGTTVNLEVDVIAKYVERLLEHR
>Mature_197_residues
MFTGIVEELGEILGREDLGDSARLTVLGPLVVEDAKHGDSIAVNGVCLTVVDVREGGVFTTDVMGETLARSSLDKIEAGA
KVNLERAAAVNSRLGGHIVQGHVDGTGNVLSRSPSENWEVVRVSLPSAVARYVVEKGSITVDGVSLTVSGLGPDWFEVSL
IPTTLDLTTLGAAAVGTTVNLEVDVIAKYVERLLEHR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=203, Percent_Identity=36.4532019704434, Blast_Score=111, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319733, Length=206, Percent_Identity=38.3495145631068, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 20702; Mature: 20702

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEELGEILGREDLGDSARLTVLGPLVVEDAKHGDSIAVNGVCLTVVDVREGGVFT
CCCHHHHHHHHHHCCCCCCCCCEEEEECCEEEECCCCCCEEEECCEEEEEEEECCCCEEE
TDVMGETLARSSLDKIEAGAKVNLERAAAVNSRLGGHIVQGHVDGTGNVLSRSPSENWEV
HHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEE
VRVSLPSAVARYVVEKGSITVDGVSLTVSGLGPDWFEVSLIPTTLDLTTLGAAAVGTTVN
EEEECHHHHHHHHHHCCCEEEECEEEEEECCCCCEEEEEEECEEECHHHHCHHHHCCEEE
LEVDVIAKYVERLLEHR
EEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFTGIVEELGEILGREDLGDSARLTVLGPLVVEDAKHGDSIAVNGVCLTVVDVREGGVFT
CCCHHHHHHHHHHCCCCCCCCCEEEEECCEEEECCCCCCEEEECCEEEEEEEECCCCEEE
TDVMGETLARSSLDKIEAGAKVNLERAAAVNSRLGGHIVQGHVDGTGNVLSRSPSENWEV
HHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEE
VRVSLPSAVARYVVEKGSITVDGVSLTVSGLGPDWFEVSLIPTTLDLTTLGAAAVGTTVN
EEEECHHHHHHHHHHCCCEEEECEEEEEECCCCCEEEEEEECEEECHHHHCHHHHCCEEE
LEVDVIAKYVERLLEHR
EEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]