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The map label for this gene is ctaB

Identifier: 169629842

GI number: 169629842

Start: 2804821

End: 2805762

Strand: Reverse

Name: ctaB

Synonym: MAB_2758c

Alternate gene names: 169629842

Gene position: 2805762-2804821 (Counterclockwise)

Preceding gene: 169629848

Following gene: 169629840

Centisome position: 55.37

GC content: 65.07

Gene sequence:

>942_bases
GTGCGGATGCGAGAGACGCAGGGCGCGCAAGGCCGTGGCCGGAACGCACCGCCCTTTCTCCGCACCATCCTCGCGTACAT
CGCGCTGACCAAGCCGCGCGTCATCGAGCTGCTGCTGGTCACCACCATTCCGGCGATGTTGCTGGCGGATCGCGGCGACG
TGAACCCGCTGCTCATCCTGAATACGCTGCTGGGTGGCGTGATGGCGGCAGCCAGCGCCAATACCCTGAATTGCGTCGCC
GACGCCGATATCGACAAGGTGATGAAGCGCACCGCACGGCGGCCGCTGGCCATGTCCTCGGTGACCACCCGTAACGCCCT
GATCTTCGGAGTCGTGCTGGGTGTGGGCGCCTTCGCGTGGTTGTGGTGGACCGCCAATCTGCTGTCGGGCCTGCTCGCCG
TGGCGACCATCGCTTTCTATGTCTTCGTCTACACGCTCGTGCTCAAGCGTCGCACCGCGCAGAACGTGGTGTGGGGCGGA
GCCGCCGGATGCATGCCGGTGATGATCGGGTGGTCGGCGGTCACGAACACGATTCAGTGGCCGGCGCTGGTGATGTTCGC
GGTCATCTTCTTCTGGACGCCGCCGCACACCTGGGCTCTCGCGATGCGGTACAAGGAGGACTACCGCGCCGCCGGAGTCC
CCATGCTGCCGGTGATCGCCACCGAGGAGAAGGTCACCAAGCTGATCCTGGTGTACACCTGGCTCACGGTGCTGTCCACG
TTGGCGCTCGCGCTGGCCGCCGGTGTCATCTACGCGGTGGTCGCTTTCCTGGCTGGGGTGTGGTTCCTGGCGATGGCGCA
CCAGCTGTACTCGGGTGTGCGCAAAGGCCAGCCCATCAGGCCGCTGCGTCTTTTCCTGCAATCGAACAACTATCTGGCTG
TGGTTTTCTGCGCGCTCGCCGTCGACTCTGTGGTCGGCTGGCCAACCCTTTTCCAGCTCTGA

Upstream 100 bases:

>100_bases
GTCGACGCCGGACCCTGGCGGTCTACCATCGTGTGTAGTAGAGCGCTCAGTGCCGCGGGTCGGCTGGCTCACCAAAAAGC
TACCCAGGAGGATCAGCGCG

Downstream 100 bases:

>100_bases
GCCGCGTCAGGGAACCAATACGACCGACCCCGTGGTCTTGCGTGCCTCCAGGTCGGTATGGGCCTGGGCGGCCTGTTCGA
GCGGGTAGCCGGCACCGATC

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRMRETQGAQGRGRNAPPFLRTILAYIALTKPRVIELLLVTTIPAMLLADRGDVNPLLILNTLLGGVMAAASANTLNCVA
DADIDKVMKRTARRPLAMSSVTTRNALIFGVVLGVGAFAWLWWTANLLSGLLAVATIAFYVFVYTLVLKRRTAQNVVWGG
AAGCMPVMIGWSAVTNTIQWPALVMFAVIFFWTPPHTWALAMRYKEDYRAAGVPMLPVIATEEKVTKLILVYTWLTVLST
LALALAAGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRPLRLFLQSNNYLAVVFCALAVDSVVGWPTLFQL

Sequences:

>Translated_313_residues
MRMRETQGAQGRGRNAPPFLRTILAYIALTKPRVIELLLVTTIPAMLLADRGDVNPLLILNTLLGGVMAAASANTLNCVA
DADIDKVMKRTARRPLAMSSVTTRNALIFGVVLGVGAFAWLWWTANLLSGLLAVATIAFYVFVYTLVLKRRTAQNVVWGG
AAGCMPVMIGWSAVTNTIQWPALVMFAVIFFWTPPHTWALAMRYKEDYRAAGVPMLPVIATEEKVTKLILVYTWLTVLST
LALALAAGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRPLRLFLQSNNYLAVVFCALAVDSVVGWPTLFQL
>Mature_313_residues
MRMRETQGAQGRGRNAPPFLRTILAYIALTKPRVIELLLVTTIPAMLLADRGDVNPLLILNTLLGGVMAAASANTLNCVA
DADIDKVMKRTARRPLAMSSVTTRNALIFGVVLGVGAFAWLWWTANLLSGLLAVATIAFYVFVYTLVLKRRTAQNVVWGG
AAGCMPVMIGWSAVTNTIQWPALVMFAVIFFWTPPHTWALAMRYKEDYRAAGVPMLPVIATEEKVTKLILVYTWLTVLST
LALALAAGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRPLRLFLQSNNYLAVVFCALAVDSVVGWPTLFQL

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily

Homologues:

Organism=Homo sapiens, GI17921982, Length=190, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786631, Length=248, Percent_Identity=34.6774193548387, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71998235, Length=252, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325085, Length=196, Percent_Identity=29.0816326530612, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19921064, Length=198, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COXX_MYCA9 (B1MC66)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703491.1
- EnsemblBacteria:   EBMYCT00000007203
- GeneID:   5965266
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2758c
- GeneTree:   EBGT00050000016790
- HOGENOM:   HBG656003
- OMA:   SYYQLTK
- ProtClustDB:   PRK04375
- BioCyc:   MABS561007:MAB_2758C-MONOMER
- HAMAP:   MF_00154
- InterPro:   IPR006369
- InterPro:   IPR000537
- PANTHER:   PTHR11048:SF3
- TIGRFAMs:   TIGR01473

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 34256; Mature: 34256

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf7d7b20)-; HASH(0xf2e1cec)-; HASH(0xfc8ec74)-; HASH(0xe9349dc)-; HASH(0xee1a5ac)-; HASH(0xeeca068)-; HASH(0xf64a7ac)-; HASH(0xf1c10f8)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMRETQGAQGRGRNAPPFLRTILAYIALTKPRVIELLLVTTIPAMLLADRGDVNPLLIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
NTLLGGVMAAASANTLNCVADADIDKVMKRTARRPLAMSSVTTRNALIFGVVLGVGAFAW
HHHHHHHHHHCCCCCEEEHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LWWTANLLSGLLAVATIAFYVFVYTLVLKRRTAQNVVWGGAAGCMPVMIGWSAVTNTIQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
PALVMFAVIFFWTPPHTWALAMRYKEDYRAAGVPMLPVIATEEKVTKLILVYTWLTVLST
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
LALALAAGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRPLRLFLQSNNYLAVVFCALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHH
VDSVVGWPTLFQL
HHHHHCCHHHHCH
>Mature Secondary Structure
MRMRETQGAQGRGRNAPPFLRTILAYIALTKPRVIELLLVTTIPAMLLADRGDVNPLLIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
NTLLGGVMAAASANTLNCVADADIDKVMKRTARRPLAMSSVTTRNALIFGVVLGVGAFAW
HHHHHHHHHHCCCCCEEEHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LWWTANLLSGLLAVATIAFYVFVYTLVLKRRTAQNVVWGGAAGCMPVMIGWSAVTNTIQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
PALVMFAVIFFWTPPHTWALAMRYKEDYRAAGVPMLPVIATEEKVTKLILVYTWLTVLST
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHH
LALALAAGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRPLRLFLQSNNYLAVVFCALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHH
VDSVVGWPTLFQL
HHHHHCCHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA