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The map label for this gene is iap [H]

Identifier: 169629812

GI number: 169629812

Start: 2776431

End: 2777861

Strand: Reverse

Name: iap [H]

Synonym: MAB_2728c

Alternate gene names: 169629812

Gene position: 2777861-2776431 (Counterclockwise)

Preceding gene: 169629813

Following gene: 169629811

Centisome position: 54.82

GC content: 65.48

Gene sequence:

>1431_bases
ATGAAGCGGACAGTGAATGACCGTTTCGCGGTGCGGGGCAAACGAACCGTGGCAACTGCGCTGATGGTGCCGCCGCTACT
GGTCGCCGGGCTGATGATGTTTCCCACGACTGTCGCAGTAACGTCCGCCGAGCCGAACGACATGGCCTCGTTGATCACGC
AGCTGGCCGATACGAACCAGCAGATCGAACAACTGACCGCCGATGTGCAGACCCAGCAAGAGTCCATCAACAAGGGGCTG
GTCGATCTGCAGGCCGCGCGTGATAACGCCGCCAGTGCCGCCGCGCAGGTCGCCGAGGGGCAGCGCGCCGTCGACGCCGC
CAACGGTGCCATCGAGGAGGCTCAGGGCAAGTTCGATCGGATGGCCGCGGCCACCTATATGGCGGGCCCGTCCACCTCAT
ATCTGACCGCGACCAATCCTGATGACGTGGTGCGTCTGGCCTCCGTGACCAAGAGTGTCGAAGCGAGCTCGCAGACGGTC
ATGGACAATCTGCGCCGGGCGCGTACCGAGCAGGTCAACAAGCAATCGCAGGCCCGGGCCATCCAGGAGAAGGCCGACCA
GGCGGCCGCGGATGCCCAACAGCAACAAGACGATCTGGTGTCCGCGATGAAGGACGTGCAGAAGAAGCTGGAGGCCCAGC
GTGGCGTCGCCGCGGACCTGACGGCCAAGAAGAAGAGTGCGGAGGCGCAGCTCGCGGCGGCGCGCGGCCCGGCCTATGCC
GCCTCGACCGCGACCGCCCGGGTGATCAACCCGAGTGCCGCGATCGCCGGCAATGGCAATGAATGGACCGAGGGCCCCGC
GCCGGTCTCCTCCGGCGGCCAGTGGGACACCACCCTCCCGATGATCGCCAGTGCCAACGTGCCCACCGACCCGACGCAGA
CCATCAACATGGTCTTGGGGATCGGCAATACCGCGGCCAATGTCGGGCAATCAGCGGTGTGCGGTGTGATCGGCATCTTC
TGCCCGAAGGCCGCCCCGGCGGCGGCGGCTTCGGGCGAGGGCGGCGAGTACCTCCCCAAGGTCTATGGCCGCGAGAACGT
GGAGCGCGTCATCGCCCGCGCCGGTAGTGCCATGGGCACGCCGTATTCCTGGGGCGGTGGCTCCTATAACGGCCCTACTC
GTGGAATCGATTCCGGTGCAGGAACTGTCGGCTATGACTGCTCCGGGCTGATGATGTACGGCTTCGCCGCGGTCGGCATC
AGGCTGCGGCACTACACCGGATACCAGTACAACTCCGGGCGCAAGGTTCCCAGCGCACAGATGAAGCGCGGCGACATGAT
CTTCTACGGCCCCAACGCAAGTCAGCACGTTGCGCTGTACCTGGGCAACGGTCAGATGCTTGAAGCGCCGAACACCGGCG
ATGTGGTCAAGGTGTCGCCGGTCCGCACCAGTGGCATGACGCCCTATGTAACCCGGATGATTGAGTGGTAG

Upstream 100 bases:

>100_bases
CTTATGTGACAACTGGGAGCGTGTCGGGGAAGGGCCGCTAATGACCGAGAAGGCTCGACCAGTGCAGAGACTTGGCAGGA
ATAGGGAGACGGCAGACGCG

Downstream 100 bases:

>100_bases
AAGTGGTGAAGGCGGCAAAGGTGCTAAAAGTGCAGGGGCTCTTCCTATTACGGTCGGCCATCGCAGTGACTATCGCCATC
GCACTGGTGTTGTTCATGGG

Product: invasion protein Inv1

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MKRTVNDRFAVRGKRTVATALMVPPLLVAGLMMFPTTVAVTSAEPNDMASLITQLADTNQQIEQLTADVQTQQESINKGL
VDLQAARDNAASAAAQVAEGQRAVDAANGAIEEAQGKFDRMAAATYMAGPSTSYLTATNPDDVVRLASVTKSVEASSQTV
MDNLRRARTEQVNKQSQARAIQEKADQAAADAQQQQDDLVSAMKDVQKKLEAQRGVAADLTAKKKSAEAQLAAARGPAYA
ASTATARVINPSAAIAGNGNEWTEGPAPVSSGGQWDTTLPMIASANVPTDPTQTINMVLGIGNTAANVGQSAVCGVIGIF
CPKAAPAAAASGEGGEYLPKVYGRENVERVIARAGSAMGTPYSWGGGSYNGPTRGIDSGAGTVGYDCSGLMMYGFAAVGI
RLRHYTGYQYNSGRKVPSAQMKRGDMIFYGPNASQHVALYLGNGQMLEAPNTGDVVKVSPVRTSGMTPYVTRMIEW

Sequences:

>Translated_476_residues
MKRTVNDRFAVRGKRTVATALMVPPLLVAGLMMFPTTVAVTSAEPNDMASLITQLADTNQQIEQLTADVQTQQESINKGL
VDLQAARDNAASAAAQVAEGQRAVDAANGAIEEAQGKFDRMAAATYMAGPSTSYLTATNPDDVVRLASVTKSVEASSQTV
MDNLRRARTEQVNKQSQARAIQEKADQAAADAQQQQDDLVSAMKDVQKKLEAQRGVAADLTAKKKSAEAQLAAARGPAYA
ASTATARVINPSAAIAGNGNEWTEGPAPVSSGGQWDTTLPMIASANVPTDPTQTINMVLGIGNTAANVGQSAVCGVIGIF
CPKAAPAAAASGEGGEYLPKVYGRENVERVIARAGSAMGTPYSWGGGSYNGPTRGIDSGAGTVGYDCSGLMMYGFAAVGI
RLRHYTGYQYNSGRKVPSAQMKRGDMIFYGPNASQHVALYLGNGQMLEAPNTGDVVKVSPVRTSGMTPYVTRMIEW
>Mature_476_residues
MKRTVNDRFAVRGKRTVATALMVPPLLVAGLMMFPTTVAVTSAEPNDMASLITQLADTNQQIEQLTADVQTQQESINKGL
VDLQAARDNAASAAAQVAEGQRAVDAANGAIEEAQGKFDRMAAATYMAGPSTSYLTATNPDDVVRLASVTKSVEASSQTV
MDNLRRARTEQVNKQSQARAIQEKADQAAADAQQQQDDLVSAMKDVQKKLEAQRGVAADLTAKKKSAEAQLAAARGPAYA
ASTATARVINPSAAIAGNGNEWTEGPAPVSSGGQWDTTLPMIASANVPTDPTQTINMVLGIGNTAANVGQSAVCGVIGIF
CPKAAPAAAASGEGGEYLPKVYGRENVERVIARAGSAMGTPYSWGGGSYNGPTRGIDSGAGTVGYDCSGLMMYGFAAVGI
RLRHYTGYQYNSGRKVPSAQMKRGDMIFYGPNASQHVALYLGNGQMLEAPNTGDVVKVSPVRTSGMTPYVTRMIEW

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=136, Percent_Identity=28.6764705882353, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787944, Length=110, Percent_Identity=29.0909090909091, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 49839; Mature: 49839

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTVNDRFAVRGKRTVATALMVPPLLVAGLMMFPTTVAVTSAEPNDMASLITQLADTNQ
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCHH
QIEQLTADVQTQQESINKGLVDLQAARDNAASAAAQVAEGQRAVDAANGAIEEAQGKFDR
HHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHH
MAAATYMAGPSTSYLTATNPDDVVRLASVTKSVEASSQTVMDNLRRARTEQVNKQSQARA
HHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQEKADQAAADAQQQQDDLVSAMKDVQKKLEAQRGVAADLTAKKKSAEAQLAAARGPAYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
ASTATARVINPSAAIAGNGNEWTEGPAPVSSGGQWDTTLPMIASANVPTDPTQTINMVLG
CCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHEEEEEE
IGNTAANVGQSAVCGVIGIFCPKAAPAAAASGEGGEYLPKVYGRENVERVIARAGSAMGT
CCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCC
PYSWGGGSYNGPTRGIDSGAGTVGYDCSGLMMYGFAAVGIRLRHYTGYQYNSGRKVPSAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCEECCCCCCCHHH
MKRGDMIFYGPNASQHVALYLGNGQMLEAPNTGDVVKVSPVRTSGMTPYVTRMIEW
HCCCCEEEECCCCCCEEEEEECCCEEEECCCCCCEEEECCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MKRTVNDRFAVRGKRTVATALMVPPLLVAGLMMFPTTVAVTSAEPNDMASLITQLADTNQ
CCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCHH
QIEQLTADVQTQQESINKGLVDLQAARDNAASAAAQVAEGQRAVDAANGAIEEAQGKFDR
HHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHH
MAAATYMAGPSTSYLTATNPDDVVRLASVTKSVEASSQTVMDNLRRARTEQVNKQSQARA
HHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQEKADQAAADAQQQQDDLVSAMKDVQKKLEAQRGVAADLTAKKKSAEAQLAAARGPAYA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
ASTATARVINPSAAIAGNGNEWTEGPAPVSSGGQWDTTLPMIASANVPTDPTQTINMVLG
CCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHEEEEEE
IGNTAANVGQSAVCGVIGIFCPKAAPAAAASGEGGEYLPKVYGRENVERVIARAGSAMGT
CCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCC
PYSWGGGSYNGPTRGIDSGAGTVGYDCSGLMMYGFAAVGIRLRHYTGYQYNSGRKVPSAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCEECCCCCCCHHH
MKRGDMIFYGPNASQHVALYLGNGQMLEAPNTGDVVKVSPVRTSGMTPYVTRMIEW
HCCCCEEEECCCCCCEEEEEECCCEEEECCCCCCEEEECCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2111287; 1459966; 11679669 [H]