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The map label for this gene is lip2 [H]

Identifier: 169629740

GI number: 169629740

Start: 2698267

End: 2699316

Strand: Direct

Name: lip2 [H]

Synonym: MAB_2655

Alternate gene names: 169629740

Gene position: 2698267-2699316 (Clockwise)

Preceding gene: 169629739

Following gene: 169629741

Centisome position: 53.25

GC content: 64.67

Gene sequence:

>1050_bases
ATGACGAGCATCACTGCGGAGGCACCGCCACGCCTGACCGTCTCCGAACTGATCCAGCGCGCCGCGTTCACAACACTGGA
CCGAATTCCGAAAGTTGTTCTTCGCCAGCTTATCCCACCGGTAGTCAACGCGGATGGCGATGTCATGGCACCGGAGATCG
CATTGCTCATGCGATTCGCCGCCGCAGCACCTGACTTCAGCGACTGTGGCGTCGCCGAAGCGAGGGCCATCATCGAAACC
GACTCCAGAGTGTTCGCGGACACCTCCGAGACCGCTGACGCAGACTCCGGCATCGTGCTCCCCAGCGGCATCCGAGCCAG
CCTCTACCGCCCAAAGACACAGTCGAACGGGTTGGTGCTGTTCCTGCACGGTGGAGGTTTCGTCCTCGGCAGCCGCACGG
CATACGACTCCCCCGCCCGGCTCATCGCGGCCCACGCCGGCGTCAACGTCCTGTCGATCGAGTATCGACTAGCCCCCGAG
GCCCCCTTCCCCGCCGCGCTCGAGGATGCCTCGGAAGCATGGCGATTCGCAGTCGGCCACAGCTCCGACTGGGGCATCGA
CCCGGCCCGTATCGTGCTGCTCGGCGACAGTGCCGGCGCAAACCTGTGCGCAGTGCTCTCGAACCAACTCCGCGATGAGG
AGATCCGGCCCAGAATGCAGGTATTGATGTACCCCGTCGTCGATGCCGTAGGTGAGTACCGTTCACGCGAGGAGTTCGCC
GACAACCCGGCACTCTCGGCCAAGCAGATCGAATGGCTGTCCGCACTGTATGTGCCCGACGCGAGCGACCGATCCGACCC
GCGCGTGTCACCGATGCTTGCCGACGATCTGTCCGGGGCGCCGGCGACGCTCATCACCGTCGCCGGTTTCGACCCGCTGC
GCGACGAGGCAATCGCCTACGCCAAGCGGCTCAAGGATTCCGGGGTATCCACGCGACTGCTACGCGAAGGCAGCCTCGTA
CACGGCTACATCTCCATGACACAGATCAGCCAGGCCGCACGCAATGCCGTCCAACGTGTCGCCGCCGCCATCAACCACGC
AGTGCGCTAA

Upstream 100 bases:

>100_bases
ACTTCAGTTCGCGGTTGGAGCGCGAACTGAAGGACAGCGGCAGCAACAGTCCTGATCGTCGCACCCAGATCAGCCGAGCA
TCTTCCGGAGGCGCGACGTC

Downstream 100 bases:

>100_bases
CGGTTACCGGCCCCGCCCACACCTATATCGAAAGTCTGAGCTTTGATCGTGTCCACAAACCGGCGAGCACTGCTTCTAGG
CGGGCTTGCGTTCACGGCCG

Product: lipase/esterase (LipN)

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTSITAEAPPRLTVSELIQRAAFTTLDRIPKVVLRQLIPPVVNADGDVMAPEIALLMRFAAAAPDFSDCGVAEARAIIET
DSRVFADTSETADADSGIVLPSGIRASLYRPKTQSNGLVLFLHGGGFVLGSRTAYDSPARLIAAHAGVNVLSIEYRLAPE
APFPAALEDASEAWRFAVGHSSDWGIDPARIVLLGDSAGANLCAVLSNQLRDEEIRPRMQVLMYPVVDAVGEYRSREEFA
DNPALSAKQIEWLSALYVPDASDRSDPRVSPMLADDLSGAPATLITVAGFDPLRDEAIAYAKRLKDSGVSTRLLREGSLV
HGYISMTQISQAARNAVQRVAAAINHAVR

Sequences:

>Translated_349_residues
MTSITAEAPPRLTVSELIQRAAFTTLDRIPKVVLRQLIPPVVNADGDVMAPEIALLMRFAAAAPDFSDCGVAEARAIIET
DSRVFADTSETADADSGIVLPSGIRASLYRPKTQSNGLVLFLHGGGFVLGSRTAYDSPARLIAAHAGVNVLSIEYRLAPE
APFPAALEDASEAWRFAVGHSSDWGIDPARIVLLGDSAGANLCAVLSNQLRDEEIRPRMQVLMYPVVDAVGEYRSREEFA
DNPALSAKQIEWLSALYVPDASDRSDPRVSPMLADDLSGAPATLITVAGFDPLRDEAIAYAKRLKDSGVSTRLLREGSLV
HGYISMTQISQAARNAVQRVAAAINHAVR
>Mature_348_residues
TSITAEAPPRLTVSELIQRAAFTTLDRIPKVVLRQLIPPVVNADGDVMAPEIALLMRFAAAAPDFSDCGVAEARAIIETD
SRVFADTSETADADSGIVLPSGIRASLYRPKTQSNGLVLFLHGGGFVLGSRTAYDSPARLIAAHAGVNVLSIEYRLAPEA
PFPAALEDASEAWRFAVGHSSDWGIDPARIVLLGDSAGANLCAVLSNQLRDEEIRPRMQVLMYPVVDAVGEYRSREEFAD
NPALSAKQIEWLSALYVPDASDRSDPRVSPMLADDLSGAPATLITVAGFDPLRDEAIAYAKRLKDSGVSTRLLREGSLVH
GYISMTQISQAARNAVQRVAAAINHAVR

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI206597554, Length=290, Percent_Identity=28.6206896551724, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI68299767, Length=306, Percent_Identity=27.4509803921569, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI157041239, Length=309, Percent_Identity=24.9190938511327, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI68051721, Length=276, Percent_Identity=26.4492753623188, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI21328446, Length=131, Percent_Identity=37.4045801526718, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI61966717, Length=285, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI226423947, Length=284, Percent_Identity=26.056338028169, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786682, Length=274, Percent_Identity=25.9124087591241, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17567059, Length=272, Percent_Identity=29.4117647058824, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI72001146, Length=135, Percent_Identity=37.7777777777778, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71996133, Length=134, Percent_Identity=38.8059701492537, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17540028, Length=131, Percent_Identity=39.6946564885496, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24656084, Length=104, Percent_Identity=36.5384615384615, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24656076, Length=104, Percent_Identity=36.5384615384615, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20130169, Length=104, Percent_Identity=36.5384615384615, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 37389; Mature: 37258

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSITAEAPPRLTVSELIQRAAFTTLDRIPKVVLRQLIPPVVNADGDVMAPEIALLMRFA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEHHHHHHHHHHH
AAAPDFSDCGVAEARAIIETDSRVFADTSETADADSGIVLPSGIRASLYRPKTQSNGLVL
HCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCCCCHHEECCCCCCCCEEE
FLHGGGFVLGSRTAYDSPARLIAAHAGVNVLSIEYRLAPEAPFPAALEDASEAWRFAVGH
EEECCCEEEECCCCCCCHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHEEECCC
SSDWGIDPARIVLLGDSAGANLCAVLSNQLRDEEIRPRMQVLMYPVVDAVGEYRSREEFA
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DNPALSAKQIEWLSALYVPDASDRSDPRVSPMLADDLSGAPATLITVAGFDPLRDEAIAY
CCCCCCHHHHHHHHHEECCCCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHH
AKRLKDSGVSTRLLREGSLVHGYISMTQISQAARNAVQRVAAAINHAVR
HHHHHHCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSITAEAPPRLTVSELIQRAAFTTLDRIPKVVLRQLIPPVVNADGDVMAPEIALLMRFA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEHHHHHHHHHHH
AAAPDFSDCGVAEARAIIETDSRVFADTSETADADSGIVLPSGIRASLYRPKTQSNGLVL
HCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCCCCHHEECCCCCCCCEEE
FLHGGGFVLGSRTAYDSPARLIAAHAGVNVLSIEYRLAPEAPFPAALEDASEAWRFAVGH
EEECCCEEEECCCCCCCHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHEEECCC
SSDWGIDPARIVLLGDSAGANLCAVLSNQLRDEEIRPRMQVLMYPVVDAVGEYRSREEFA
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DNPALSAKQIEWLSALYVPDASDRSDPRVSPMLADDLSGAPATLITVAGFDPLRDEAIAY
CCCCCCHHHHHHHHHEECCCCCCCCCCCCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHH
AKRLKDSGVSTRLLREGSLVHGYISMTQISQAARNAVQRVAAAINHAVR
HHHHHHCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]