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The map label for this gene is trpB [H]

Identifier: 169629729

GI number: 169629729

Start: 2684700

End: 2685959

Strand: Reverse

Name: trpB [H]

Synonym: MAB_2644c

Alternate gene names: 169629729

Gene position: 2685959-2684700 (Counterclockwise)

Preceding gene: 169629730

Following gene: 169629728

Centisome position: 53.01

GC content: 63.41

Gene sequence:

>1260_bases
ATGAAGAACACCGGCCTGCCGCAGATGAGCACTGCGATCGCTGAGCCCACCGCGCACGATCCTGACGCCCGGGGCCATTT
CGGTCCGTACGGTGGCCGCTACGTGGCCGAGGCACTGATGGCCGTCATCGAGGAAGTAACGGCCGCCTACGAAAAGATCA
GGTCCGACCGGTCATTCCTCGACGAACTCGATCGCTTGCAGACCCACTACGTGGGACGCCCATCGCCGCTGTACGAAGCG
GAACGACTTAGTGCTCACGCCGGCGGCGCACGTATCTTTCTCAAACGAGAAGACCTGAACCACACTGGTTCTCACAAGAT
CAACAACGTTCTCGGTCAAGTTCTACTGGCCAAGAAGATGGGCAAGACCCGCGTGATCGCCGAGACCGGTGCCGGGCAGC
ACGGTGTTGCCACCGCCACCGCATGCGCGCTGCTGGGCCTGGAATGCGTGATTTACATGGGCGCGGTCGACACCGCACGG
CAAGCCCTCAATGTCGCGCGGATGCGGCTGTTGGGATCGACCGTGGTGTCGGTGGAATCGGGGTCGAAAACCCTCAAGGA
CGCGATCAATGACGCGATGCGTGACTGGGTAACCAACGCGCACAACACCTATTACTGCTTCGGTACGGCCGCCGGGCCGC
ACCCCTTTCCGGTGATGGTCCGCGATTTTCAGCGCATCATCGGTATGGAGGCGCGGGCGCAAGTTCTCGATCAAGTGGGC
AGATTGCCGGATGCGGCAGTGGCCTGCGTCGGCGGCGGCTCCAACGCCATCGGCCTGTTCCATGCGTTTATCGATGATCC
GGCAGTGCGCCTGGTGGGCTACGAGGCTGCGGGTGACGGTGTCGAAACCGGAAGGCACGCCGCCACATTCACCGGTGGTA
CCCCGGGCGCTTTCCAGGGCTCCTACTCTTATCTGCTCCAGGACGACGACGGTCAGACCATCGAATCTCATTCGATCTCA
GCCGGTCTGGACTACCCGGGAGTCGGACCGGAGCACGCCTGGCTGCGTGAGAGCGGGCGCGCGGACTACCGTCCGATCAC
CGACGGCGAGGCCATGGATGCCTTCCTGTTGCTTTCGCGTGCAGAGGGCATCATCCCCGCCATCGAATCGGCGCACGCCG
TGGCCGGCGCACTCAAACTCGGCGGCGAGTTGAGCGAGGGCGCGGTCATCGTGGTGAGCCTGTCGGGTCGCGGCGACAAG
GATGTCGAGACCGCCGCCAAGTGGTTCGACCTACTGGAGAAGGACGGCAGCCAGTCATGA

Upstream 100 bases:

>100_bases
GTGAGGGGCTGGTGACCAGCGGAGACCCCCGAGGTGCGGTCGCCGATCTGGTGACCGCGGGCACGCATCCGTCCTGCCCC
AAACCGGCTCGCTAGACGTC

Downstream 100 bases:

>100_bases
CACAGCCCGGCCGTCTGACCGAGGTCTTCGACAAGTGCCGCGCCGAAGAACGCGCCGCGCTGATCGGGTACCTGCCCAAC
GGTTACCCGGACCTGGACAC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKNTGLPQMSTAIAEPTAHDPDARGHFGPYGGRYVAEALMAVIEEVTAAYEKIRSDRSFLDELDRLQTHYVGRPSPLYEA
ERLSAHAGGARIFLKREDLNHTGSHKINNVLGQVLLAKKMGKTRVIAETGAGQHGVATATACALLGLECVIYMGAVDTAR
QALNVARMRLLGSTVVSVESGSKTLKDAINDAMRDWVTNAHNTYYCFGTAAGPHPFPVMVRDFQRIIGMEARAQVLDQVG
RLPDAAVACVGGGSNAIGLFHAFIDDPAVRLVGYEAAGDGVETGRHAATFTGGTPGAFQGSYSYLLQDDDGQTIESHSIS
AGLDYPGVGPEHAWLRESGRADYRPITDGEAMDAFLLLSRAEGIIPAIESAHAVAGALKLGGELSEGAVIVVSLSGRGDK
DVETAAKWFDLLEKDGSQS

Sequences:

>Translated_419_residues
MKNTGLPQMSTAIAEPTAHDPDARGHFGPYGGRYVAEALMAVIEEVTAAYEKIRSDRSFLDELDRLQTHYVGRPSPLYEA
ERLSAHAGGARIFLKREDLNHTGSHKINNVLGQVLLAKKMGKTRVIAETGAGQHGVATATACALLGLECVIYMGAVDTAR
QALNVARMRLLGSTVVSVESGSKTLKDAINDAMRDWVTNAHNTYYCFGTAAGPHPFPVMVRDFQRIIGMEARAQVLDQVG
RLPDAAVACVGGGSNAIGLFHAFIDDPAVRLVGYEAAGDGVETGRHAATFTGGTPGAFQGSYSYLLQDDDGQTIESHSIS
AGLDYPGVGPEHAWLRESGRADYRPITDGEAMDAFLLLSRAEGIIPAIESAHAVAGALKLGGELSEGAVIVVSLSGRGDK
DVETAAKWFDLLEKDGSQS
>Mature_419_residues
MKNTGLPQMSTAIAEPTAHDPDARGHFGPYGGRYVAEALMAVIEEVTAAYEKIRSDRSFLDELDRLQTHYVGRPSPLYEA
ERLSAHAGGARIFLKREDLNHTGSHKINNVLGQVLLAKKMGKTRVIAETGAGQHGVATATACALLGLECVIYMGAVDTAR
QALNVARMRLLGSTVVSVESGSKTLKDAINDAMRDWVTNAHNTYYCFGTAAGPHPFPVMVRDFQRIIGMEARAQVLDQVG
RLPDAAVACVGGGSNAIGLFHAFIDDPAVRLVGYEAAGDGVETGRHAATFTGGTPGAFQGSYSYLLQDDDGQTIESHSIS
AGLDYPGVGPEHAWLRESGRADYRPITDGEAMDAFLLLSRAEGIIPAIESAHAVAGALKLGGELSEGAVIVVSLSGRGDK
DVETAAKWFDLLEKDGSQS

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=392, Percent_Identity=53.0612244897959, Blast_Score=412, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321412, Length=382, Percent_Identity=56.282722513089, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44466; Mature: 44466

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTGLPQMSTAIAEPTAHDPDARGHFGPYGGRYVAEALMAVIEEVTAAYEKIRSDRSFL
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELDRLQTHYVGRPSPLYEAERLSAHAGGARIFLKREDLNHTGSHKINNVLGQVLLAKKM
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHC
GKTRVIAETGAGQHGVATATACALLGLECVIYMGAVDTARQALNVARMRLLGSTVVSVES
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECC
GSKTLKDAINDAMRDWVTNAHNTYYCFGTAAGPHPFPVMVRDFQRIIGMEARAQVLDQVG
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHC
RLPDAAVACVGGGSNAIGLFHAFIDDPAVRLVGYEAAGDGVETGRHAATFTGGTPGAFQG
CCCCHHEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCC
SYSYLLQDDDGQTIESHSISAGLDYPGVGPEHAWLRESGRADYRPITDGEAMDAFLLLSR
CEEEEEECCCCCEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
AEGIIPAIESAHAVAGALKLGGELSEGAVIVVSLSGRGDKDVETAAKWFDLLEKDGSQS
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKNTGLPQMSTAIAEPTAHDPDARGHFGPYGGRYVAEALMAVIEEVTAAYEKIRSDRSFL
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELDRLQTHYVGRPSPLYEAERLSAHAGGARIFLKREDLNHTGSHKINNVLGQVLLAKKM
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHC
GKTRVIAETGAGQHGVATATACALLGLECVIYMGAVDTARQALNVARMRLLGSTVVSVES
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECC
GSKTLKDAINDAMRDWVTNAHNTYYCFGTAAGPHPFPVMVRDFQRIIGMEARAQVLDQVG
CHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHC
RLPDAAVACVGGGSNAIGLFHAFIDDPAVRLVGYEAAGDGVETGRHAATFTGGTPGAFQG
CCCCHHEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCCCC
SYSYLLQDDDGQTIESHSISAGLDYPGVGPEHAWLRESGRADYRPITDGEAMDAFLLLSR
CEEEEEECCCCCEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
AEGIIPAIESAHAVAGALKLGGELSEGAVIVVSLSGRGDKDVETAAKWFDLLEKDGSQS
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]