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The map label for this gene is sugE [H]

Identifier: 169629725

GI number: 169629725

Start: 2682107

End: 2682421

Strand: Reverse

Name: sugE [H]

Synonym: MAB_2640c

Alternate gene names: 169629725

Gene position: 2682421-2682107 (Counterclockwise)

Preceding gene: 169629726

Following gene: 169629724

Centisome position: 52.94

GC content: 62.54

Gene sequence:

>315_bases
ATGGTGTGGTTGGTCCTAGTTCTCGCGGGTCTGCTCGAGGTGGGCTGGGCCATCGGCCTCAAATACACCGAGGGTTTCAC
GCGGTTGTGGCCCACGGTCGGAACTGTCGGCTCGATGATCATCAGCATCGCGCTGCTGGGCATCGCGATGAAGAGTCTGC
CGGTGGGCACCGCGTATGCGATCTGGGTCGGTGTCGGAGCCGTCGGGACCGCGATCCTTGGCATCGTGCTGTTCGGCGAC
TCCGCCAACGTTTGGCGGCTGCTTAGCCTCGGATTGATCGTGGCAGGGATCATCGGCCTCAAATTGGCGACCTGA

Upstream 100 bases:

>100_bases
GCCAGCTTCGGGATTGACGTGTGCGAGAATTGAGGTGACCGGGACGGCCCGGTCATTCTTTCGCCAGGGGACGGCCTCAC
CGAATACGGAGGTATCTCTC

Downstream 100 bases:

>100_bases
CAACGCAAACCGTTGAAGGTAACCGGTGAGTGAATCGTGCCCGCGCTGACTCGTGAGTAGGTGGCACCCCGACTATGCTC
AAAAGTCGTGACGAGACGCG

Product: putative multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MVWLVLVLAGLLEVGWAIGLKYTEGFTRLWPTVGTVGSMIISIALLGIAMKSLPVGTAYAIWVGVGAVGTAILGIVLFGD
SANVWRLLSLGLIVAGIIGLKLAT

Sequences:

>Translated_104_residues
MVWLVLVLAGLLEVGWAIGLKYTEGFTRLWPTVGTVGSMIISIALLGIAMKSLPVGTAYAIWVGVGAVGTAILGIVLFGD
SANVWRLLSLGLIVAGIIGLKLAT
>Mature_104_residues
MVWLVLVLAGLLEVGWAIGLKYTEGFTRLWPTVGTVGSMIISIALLGIAMKSLPVGTAYAIWVGVGAVGTAILGIVLFGD
SANVWRLLSLGLIVAGIIGLKLAT

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=71.1538461538462, Blast_Score=136, Evalue=3e-34,
Organism=Escherichia coli, GI1786755, Length=83, Percent_Identity=40.9638554216867, Blast_Score=62, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10750; Mature: 10750

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLVLVLAGLLEVGWAIGLKYTEGFTRLWPTVGTVGSMIISIALLGIAMKSLPVGTAYA
CHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWVGVGAVGTAILGIVLFGDSANVWRLLSLGLIVAGIIGLKLAT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVWLVLVLAGLLEVGWAIGLKYTEGFTRLWPTVGTVGSMIISIALLGIAMKSLPVGTAYA
CHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWVGVGAVGTAILGIVLFGDSANVWRLLSLGLIVAGIIGLKLAT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]