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The map label for this gene is livH [H]

Identifier: 169629710

GI number: 169629710

Start: 2665579

End: 2666649

Strand: Reverse

Name: livH [H]

Synonym: MAB_2625c

Alternate gene names: 169629710

Gene position: 2666649-2665579 (Counterclockwise)

Preceding gene: 169629711

Following gene: 169629709

Centisome position: 52.63

GC content: 62.28

Gene sequence:

>1071_bases
ATGATTTCGGGGTGGATGGCACAGACGGGTGTGCAGGCCAGCACAATTTCATTCGATCTGCACGGACTGTGGAGCAGCAT
CGGACAACTGACCATTGACGGTTTGGCATGGGGCGCCATCTATGCGCTGGTCGCGGTCGGCTACACGCTGGTCTTCGGGG
TGCTGCGGCTTATCAACTTCGCGCACTCGGAAGTTTTCATGTTGGGCATGTTCGGGGCGTATTTCGCACTCGATGTGGTG
CTCGGATTCTCGCCGGGCGGCAATGCCTACAACAAAGGCGTGTCACTGACCGTGCTGTACCTGGGTGTAGCCATGCTCGT
CGCCATGGCCGTGTCGGCCACGACCGCACTGGGCCTGGAGGCCGTTGCGTACCGGCCGCTGCGGCGCCGTGGTGCGCGGC
CGTTGACCTTTCTCATCACCGCCATCGGTATGTCCTTCGTGATCCAGGAGTTTGTGCACTGGGTATTGCCGAAGATCGCC
AAGGGGTACGGCGGTAGCAACGCACAGCAGCCGCTCATGCTGGTGACTCCCAGGCCGGTGTGGACGTTCGGTCCCTTCGA
CGTGAGCGGCCACCACATCCCGTTCCAGGCGACGATCACCAATGTCACCGTCGTCGTGGTCGCGGCGGCGCTGGTGCTGG
CGTTCGTGACGGATATCGCGATCAATCACACCAAGTTCGGACGCGGCATTCGTGCCGTCGCACAAGATTCCACGACGGCG
ACGCTGATGGGTGTCTCCCGCGAACGCATCATCATGGCGACCTTCGTCATCGGCGGCCTGCTGGCCGGCGCCGCGGCGCT
GCTGTACACGTTGAAGGTGCCGCAGGGCATCATCTACTCGGGTGGGTTCTTGTTGGGTATCAAGGCGTTCTCGGCCGCGG
TGCTTGGTGGTATCGGCAATCTTCGCGGTGCGTTGCTTGGCGGCTTGATCCTGGGCGTGATGGAGAACTACGGCCAGGCG
GTATTTGGCACGCAGTGGCGCGATGTGGTGGCGTTCGTACTGCTGGTGTTGGTGCTCATGTTCCGTCCCACCGGCATTCT
CGGCGAGAGCCTAGGGCGGGCAAAGGCATGA

Upstream 100 bases:

>100_bases
GCGAGAGTACAAGTGGAACGAAAACGGGGAGCTAACTTCCACACTTATCTGGGTGTATAAGGTCACGTAACACATACGAG
GGGACTAGGCTCAGCCGCAA

Downstream 100 bases:

>100_bases
GCGCAGCACGTGCCCTGGCACCCGGCGACTCCATCCGACGGTGGTGGTCCGAGCTGGCCCGTCCGGTGCAGTGGGTGTAC
GGGGTAGTCGGATTCGCATT

Product: branched chain amino acid ABC transporter

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MISGWMAQTGVQASTISFDLHGLWSSIGQLTIDGLAWGAIYALVAVGYTLVFGVLRLINFAHSEVFMLGMFGAYFALDVV
LGFSPGGNAYNKGVSLTVLYLGVAMLVAMAVSATTALGLEAVAYRPLRRRGARPLTFLITAIGMSFVIQEFVHWVLPKIA
KGYGGSNAQQPLMLVTPRPVWTFGPFDVSGHHIPFQATITNVTVVVVAAALVLAFVTDIAINHTKFGRGIRAVAQDSTTA
TLMGVSRERIIMATFVIGGLLAGAAALLYTLKVPQGIIYSGGFLLGIKAFSAAVLGGIGNLRGALLGGLILGVMENYGQA
VFGTQWRDVVAFVLLVLVLMFRPTGILGESLGRAKA

Sequences:

>Translated_356_residues
MISGWMAQTGVQASTISFDLHGLWSSIGQLTIDGLAWGAIYALVAVGYTLVFGVLRLINFAHSEVFMLGMFGAYFALDVV
LGFSPGGNAYNKGVSLTVLYLGVAMLVAMAVSATTALGLEAVAYRPLRRRGARPLTFLITAIGMSFVIQEFVHWVLPKIA
KGYGGSNAQQPLMLVTPRPVWTFGPFDVSGHHIPFQATITNVTVVVVAAALVLAFVTDIAINHTKFGRGIRAVAQDSTTA
TLMGVSRERIIMATFVIGGLLAGAAALLYTLKVPQGIIYSGGFLLGIKAFSAAVLGGIGNLRGALLGGLILGVMENYGQA
VFGTQWRDVVAFVLLVLVLMFRPTGILGESLGRAKA
>Mature_356_residues
MISGWMAQTGVQASTISFDLHGLWSSIGQLTIDGLAWGAIYALVAVGYTLVFGVLRLINFAHSEVFMLGMFGAYFALDVV
LGFSPGGNAYNKGVSLTVLYLGVAMLVAMAVSATTALGLEAVAYRPLRRRGARPLTFLITAIGMSFVIQEFVHWVLPKIA
KGYGGSNAQQPLMLVTPRPVWTFGPFDVSGHHIPFQATITNVTVVVVAAALVLAFVTDIAINHTKFGRGIRAVAQDSTTA
TLMGVSRERIIMATFVIGGLLAGAAALLYTLKVPQGIIYSGGFLLGIKAFSAAVLGGIGNLRGALLGGLILGVMENYGQA
VFGTQWRDVVAFVLLVLVLMFRPTGILGESLGRAKA

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=322, Percent_Identity=36.0248447204969, Blast_Score=168, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 37570; Mature: 37570

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGWMAQTGVQASTISFDLHGLWSSIGQLTIDGLAWGAIYALVAVGYTLVFGVLRLINF
CCCCCHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHSEVFMLGMFGAYFALDVVLGFSPGGNAYNKGVSLTVLYLGVAMLVAMAVSATTALGLE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAYRPLRRRGARPLTFLITAIGMSFVIQEFVHWVLPKIAKGYGGSNAQQPLMLVTPRPV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCC
WTFGPFDVSGHHIPFQATITNVTVVVVAAALVLAFVTDIAINHTKFGRGIRAVAQDSTTA
EEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHCCCCHH
TLMGVSRERIIMATFVIGGLLAGAAALLYTLKVPQGIIYSGGFLLGIKAFSAAVLGGIGN
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCHHH
LRGALLGGLILGVMENYGQAVFGTQWRDVVAFVLLVLVLMFRPTGILGESLGRAKA
HHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
>Mature Secondary Structure
MISGWMAQTGVQASTISFDLHGLWSSIGQLTIDGLAWGAIYALVAVGYTLVFGVLRLINF
CCCCCHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHSEVFMLGMFGAYFALDVVLGFSPGGNAYNKGVSLTVLYLGVAMLVAMAVSATTALGLE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAYRPLRRRGARPLTFLITAIGMSFVIQEFVHWVLPKIAKGYGGSNAQQPLMLVTPRPV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCC
WTFGPFDVSGHHIPFQATITNVTVVVVAAALVLAFVTDIAINHTKFGRGIRAVAQDSTTA
EEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHCCCCHH
TLMGVSRERIIMATFVIGGLLAGAAALLYTLKVPQGIIYSGGFLLGIKAFSAAVLGGIGN
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCHHH
LRGALLGGLILGVMENYGQAVFGTQWRDVVAFVLLVLVLMFRPTGILGESLGRAKA
HHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]