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The map label for this gene is ycgM [C]

Identifier: 169629661

GI number: 169629661

Start: 2620325

End: 2621263

Strand: Reverse

Name: ycgM [C]

Synonym: MAB_2575c

Alternate gene names: 169629661

Gene position: 2621263-2620325 (Counterclockwise)

Preceding gene: 169629662

Following gene: 169629660

Centisome position: 51.73

GC content: 61.34

Gene sequence:

>939_bases
ATGACCATCGCAATCCTGCGCACCGCCGACGCCTGGTGGGTGCACACCGCCACCGGCGCCGTGCGAATCGACAGCTCGGC
AACGACCACCGGCGGGCTACTCTCCGATCGGGCCGCCATAGCCGCCGCGACGCGTGGCGGCGACGCAGTGCCTATCGACG
CCCTTGAGCTGCTCTCCCCCGTCACCGCTCCCTGCCGTGTGGTCGCTCAGATGACCAACTTCGCCTCGCATGTCAAAGAC
GCCGGCATGGACCCAAAGACCATCCCGCTCACGTTTTTTCGCAAGTCTTCTAGCTCGATCAGCGGACCTTTCGACGACAT
CGTCAAACCCGCCCACGTGCAGTACCTGGACTACGAAGTAGAGATCGGCATCGTGATCGGACAAACCATCGAGGTGGGTT
CGGTGATCACCCGGGACAATCTGGCCGACTACATCACGGCCTGGGTGGTGACCAATGATGTGTCGGCCCGCGACGTGCAA
CTGACCAAAACCCAATTTTACGAAGCCAAATCATATCCAACGTTCACACCGGTTGGCCCGTCACTGGTACTGATCGATCC
TGCTGAACTGCAACGATTTAACGAGCTGCGGCTCCAGTTAAAGGTCAACGGGCAACTCCGCCAGAACATGCTGGTCGGCG
CCGACATGATCTTCTCGCCGCTGCAGGCGCTACAGGCGCTGACCCGATTCCAACGTCTTGACGCCGGAGATCTGCTGTTG
ACAGGAACACCGGTCGGCACCGCACTCAGCGCCCCACCCAAACCGGTCGAAAAGATCGGTGCGCTGCTACCGCCCGCACT
CAAATGGCGGCTGTTCTTCGCCTCTCAGGGCAAAAACCCCAAGTACCTGCACGACGGCGACGTGGTGGAGGCCTCGGTGG
CCACCGATGACGGCAGCATCTGCCTGGGAACCCAGCGCACCACGGTGAGATTCTCGTGA

Upstream 100 bases:

>100_bases
AATCCCTACCTCACGAAGCACAGTCGATCTTCGCGGCCCTGCGAGGCGACAACGAATTCGATATCAACCGACTCATCGGC
CTACTGAAAGTAGCGAACTC

Downstream 100 bases:

>100_bases
AGTCCGACGATCTATTGTGGCCTTGCTACCGCGGGCCCGAGGATCTGGCCGCGATCGAATCGATCCCGTTGTCGCAGCGC
GGCCTGCCGGTATCGACCTA

Product: putative fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MTIAILRTADAWWVHTATGAVRIDSSATTTGGLLSDRAAIAAATRGGDAVPIDALELLSPVTAPCRVVAQMTNFASHVKD
AGMDPKTIPLTFFRKSSSSISGPFDDIVKPAHVQYLDYEVEIGIVIGQTIEVGSVITRDNLADYITAWVVTNDVSARDVQ
LTKTQFYEAKSYPTFTPVGPSLVLIDPAELQRFNELRLQLKVNGQLRQNMLVGADMIFSPLQALQALTRFQRLDAGDLLL
TGTPVGTALSAPPKPVEKIGALLPPALKWRLFFASQGKNPKYLHDGDVVEASVATDDGSICLGTQRTTVRFS

Sequences:

>Translated_312_residues
MTIAILRTADAWWVHTATGAVRIDSSATTTGGLLSDRAAIAAATRGGDAVPIDALELLSPVTAPCRVVAQMTNFASHVKD
AGMDPKTIPLTFFRKSSSSISGPFDDIVKPAHVQYLDYEVEIGIVIGQTIEVGSVITRDNLADYITAWVVTNDVSARDVQ
LTKTQFYEAKSYPTFTPVGPSLVLIDPAELQRFNELRLQLKVNGQLRQNMLVGADMIFSPLQALQALTRFQRLDAGDLLL
TGTPVGTALSAPPKPVEKIGALLPPALKWRLFFASQGKNPKYLHDGDVVEASVATDDGSICLGTQRTTVRFS
>Mature_311_residues
TIAILRTADAWWVHTATGAVRIDSSATTTGGLLSDRAAIAAATRGGDAVPIDALELLSPVTAPCRVVAQMTNFASHVKDA
GMDPKTIPLTFFRKSSSSISGPFDDIVKPAHVQYLDYEVEIGIVIGQTIEVGSVITRDNLADYITAWVVTNDVSARDVQL
TKTQFYEAKSYPTFTPVGPSLVLIDPAELQRFNELRLQLKVNGQLRQNMLVGADMIFSPLQALQALTRFQRLDAGDLLLT
GTPVGTALSAPPKPVEKIGALLPPALKWRLFFASQGKNPKYLHDGDVVEASVATDDGSICLGTQRTTVRFS

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=232, Percent_Identity=31.8965517241379, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI40786394, Length=232, Percent_Identity=31.4655172413793, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI66348062, Length=189, Percent_Identity=30.1587301587302, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI215422413, Length=189, Percent_Identity=30.1587301587302, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI13654274, Length=189, Percent_Identity=30.1587301587302, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787428, Length=186, Percent_Identity=28.494623655914, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17557057, Length=185, Percent_Identity=30.8108108108108, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28572127, Length=251, Percent_Identity=28.6852589641434, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24663695, Length=214, Percent_Identity=26.1682242990654, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 33610; Mature: 33479

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAILRTADAWWVHTATGAVRIDSSATTTGGLLSDRAAIAAATRGGDAVPIDALELLSP
CEEEEEEECCCEEEEECCCEEEECCCCCCCCCCHHCCHHEEEECCCCCCCCHHHHHHHCC
VTAPCRVVAQMTNFASHVKDAGMDPKTIPLTFFRKSSSSISGPFDDIVKPAHVQYLDYEV
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHCCCCEEEEEEEEE
EIGIVIGQTIEVGSVITRDNLADYITAWVVTNDVSARDVQLTKTQFYEAKSYPTFTPVGP
EEEEEEECEEECCCEEECCHHHHHEEEEEEECCCCCCEEEEEHHHHHHCCCCCCCCCCCC
SLVLIDPAELQRFNELRLQLKVNGQLRQNMLVGADMIFSPLQALQALTRFQRLDAGDLLL
CEEEECHHHHHHHEEEEEEEEECCCCHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
TGTPVGTALSAPPKPVEKIGALLPPALKWRLFFASQGKNPKYLHDGDVVEASVATDDGSI
ECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCEECCCCEEEEEEECCCCCE
CLGTQRTTVRFS
EEECCCEEEEEC
>Mature Secondary Structure 
TIAILRTADAWWVHTATGAVRIDSSATTTGGLLSDRAAIAAATRGGDAVPIDALELLSP
EEEEEEECCCEEEEECCCEEEECCCCCCCCCCHHCCHHEEEECCCCCCCCHHHHHHHCC
VTAPCRVVAQMTNFASHVKDAGMDPKTIPLTFFRKSSSSISGPFDDIVKPAHVQYLDYEV
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHCCCCEEEEEEEEE
EIGIVIGQTIEVGSVITRDNLADYITAWVVTNDVSARDVQLTKTQFYEAKSYPTFTPVGP
EEEEEEECEEECCCEEECCHHHHHEEEEEEECCCCCCEEEEEHHHHHHCCCCCCCCCCCC
SLVLIDPAELQRFNELRLQLKVNGQLRQNMLVGADMIFSPLQALQALTRFQRLDAGDLLL
CEEEECHHHHHHHEEEEEEEEECCCCHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
TGTPVGTALSAPPKPVEKIGALLPPALKWRLFFASQGKNPKYLHDGDVVEASVATDDGSI
ECCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCEECCCCEEEEEEECCCCCE
CLGTQRTTVRFS
EEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]