Click here to switch to the map view.

The map label for this gene is arsC1 [H]

Identifier: 169629654

GI number: 169629654

Start: 2611698

End: 2612117

Strand: Direct

Name: arsC1 [H]

Synonym: MAB_2568

Alternate gene names: 169629654

Gene position: 2611698-2612117 (Clockwise)

Preceding gene: 169629653

Following gene: 169629663

Centisome position: 51.54

GC content: 59.05

Gene sequence:

>420_bases
ATGACCGATAAGCCGACGGTGCTGTTCTTATGTACCCACAATGCCGGGCGCTCCCAAATGGCACTGGGGTACTTTACGAA
TCTGGCCAGAGGCAACGCGGTCGGAATGTCGGGTGGTTCCGAGCCGGCCGACCAGATCAACCCCGCCGCAATCGCAGTCA
TGCACGAAGTGGGTATCGATATCACCACCGAGTATCCCAAACCGTGGTCGGTCGAAACTGTGCAGGCCGCTGATGTCGTG
GTCACGATGGGCTGTGACGACAGCTGCCCGTATTTTCCCGGAAAGCGCTACGAGAATTGGGAGCTCGCCGACCCTGCCGG
ACAATCCGTAGAAGCTATACGGCCGATTCGTGACGACATCGAACAGCGAGTGAGGGAACTGTTGATCAGCCTCGGCGTTG
CCGGCGTTGTGGAGCCCTGA

Upstream 100 bases:

>100_bases
GTGCCGGTGTTGGTGGCGTTGGTGTACGTCTCACTCGCGCTGCGACGGCGATTCGATCCTGAAACTCAGCACGCTTCGCA
TACTGAAGAGGATCCGAACG

Downstream 100 bases:

>100_bases
GCTGTTGTCGCCGCACTAATCTGGTTGGGGCACCGAGAGAAATCCAACTCGATTTCGCCTTCGGTCTTGACCTGCTCATC
AAAGGACTGACGCAACGGCG

Product: putative arsenate reductase or tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase 1; Arsenical pump modifier 1; Low molecular weight protein-tyrosine-phosphatase 1 [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MTDKPTVLFLCTHNAGRSQMALGYFTNLARGNAVGMSGGSEPADQINPAAIAVMHEVGIDITTEYPKPWSVETVQAADVV
VTMGCDDSCPYFPGKRYENWELADPAGQSVEAIRPIRDDIEQRVRELLISLGVAGVVEP

Sequences:

>Translated_139_residues
MTDKPTVLFLCTHNAGRSQMALGYFTNLARGNAVGMSGGSEPADQINPAAIAVMHEVGIDITTEYPKPWSVETVQAADVV
VTMGCDDSCPYFPGKRYENWELADPAGQSVEAIRPIRDDIEQRVRELLISLGVAGVVEP
>Mature_138_residues
TDKPTVLFLCTHNAGRSQMALGYFTNLARGNAVGMSGGSEPADQINPAAIAVMHEVGIDITTEYPKPWSVETVQAADVVV
TMGCDDSCPYFPGKRYENWELADPAGQSVEAIRPIRDDIEQRVRELLISLGVAGVVEP

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 15008; Mature: 14877

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKPTVLFLCTHNAGRSQMALGYFTNLARGNAVGMSGGSEPADQINPAAIAVMHEVGID
CCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHCCHHHEEEEHHCCCE
ITTEYPKPWSVETVQAADVVVTMGCDDSCPYFPGKRYENWELADPAGQSVEAIRPIRDDI
EEECCCCCCCCEEEEECEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EQRVRELLISLGVAGVVEP
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDKPTVLFLCTHNAGRSQMALGYFTNLARGNAVGMSGGSEPADQINPAAIAVMHEVGID
CCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHCCHHHEEEEHHCCCE
ITTEYPKPWSVETVQAADVVVTMGCDDSCPYFPGKRYENWELADPAGQSVEAIRPIRDDI
EEECCCCCCCCEEEEECEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
EQRVRELLISLGVAGVVEP
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA