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The map label for this gene is arsB [H]

Identifier: 169629653

GI number: 169629653

Start: 2610593

End: 2611708

Strand: Direct

Name: arsB [H]

Synonym: MAB_2567

Alternate gene names: 169629653

Gene position: 2610593-2611708 (Clockwise)

Preceding gene: 169629652

Following gene: 169629654

Centisome position: 51.52

GC content: 61.74

Gene sequence:

>1116_bases
ATGAGCCAGGCGACGGCCGCGCGCAATGCGGACACCACGGTAGGAAAGCTCTCGACGCTAGATCGCTACTTGCCGCTGTG
GATCGGACTGGCAATGGCTGCCGGACTGCTGCTTGGACGAAACGTTCCCGGCCTGAACTCGGCGCTGGAAAAGGTTCAGG
TCGACGGCATTTCACTGCCCATTGCTGTCGGCCTACTGATCATGATGTACCCGGTGTTGGCCAAGGTGCGCTACGACCGC
CTCGGCTCCGTTGCCGGTGACCGCAAGCTGCTGGCCGGGTCCCTCGTGCTGAACTGGGTGCTGGGCCCGGCCCTGATGTT
CACCTTGGCGTGGCTGTTGCTGCCAGATCTGCCGGAGTATCGCACCGGACTGATCATCGTGGGCCTGGCCAGATGCATTG
CCATGGTGATCATCTGGAACGATCTGGCGTGCGGAGACCGCGAATCAGCCGCCGTGCTGGTGGCCCTGAACTCACTGTTC
CAGGTGCTGACGTTCGCGGCCCTGGGCTGGTTCTATTTGTCGGTGCTGCCCGGCTGGTTGCACCTGCCTCAAACAGCCAT
CACGGCCTCACCGTGGGAGATCGCCACATCAGTCTTGATATTTCTGGGAATACCGCTGATGGCCGGATATCTGTCCCGAC
GGTTCGGCGAGAAGGTCAGAGGGCGTGGCTGGTACGAGTCGAAGTTCCTGCCAGCGATCAGCCCGTGGGCGCTATACGGA
TTGTTGTTCACCATCGTGATTCTCTTCGCGTTACAAGGCGCCCAAATCACCTCCCATCCCTGGGACGTGGCACGAATCGC
GCTGCCGCTGCTGGCCTATTTCGCCATCATGTGGGGCGGGGGATACCTGCTCGGCGCATCCCTCGGCCTCGGGTATGCGC
GTACCACCACGCTGGCATTTACCGCCGCGGGAAACAACTTTGAGCTGGCGATCGCGGTGGCCATCGCCACTTATGGTGCG
ACCTCCGGTCAAGCCTTGGCCGGGGTGGTCGGGCCACTCATCGAGGTGCCGGTGTTGGTGGCGTTGGTGTACGTCTCACT
CGCGCTGCGACGGCGATTCGATCCTGAAACTCAGCACGCTTCGCATACTGAAGAGGATCCGAACGATGACCGATAA

Upstream 100 bases:

>100_bases
TCTACGCGGTGTTGGCCGACTCGGAGACCTTCGGTGACACCCCACGGCTGACCGACAAGAATCCTGGCGGTAGTACGGCG
CCTTCTTGCTGCGCCACGTC

Downstream 100 bases:

>100_bases
GCCGACGGTGCTGTTCTTATGTACCCACAATGCCGGGCGCTCCCAAATGGCACTGGGGTACTTTACGAATCTGGCCAGAG
GCAACGCGGTCGGAATGTCG

Product: arsenic-transport integral membrane protein ArsC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSQATAARNADTTVGKLSTLDRYLPLWIGLAMAAGLLLGRNVPGLNSALEKVQVDGISLPIAVGLLIMMYPVLAKVRYDR
LGSVAGDRKLLAGSLVLNWVLGPALMFTLAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDRESAAVLVALNSLF
QVLTFAALGWFYLSVLPGWLHLPQTAITASPWEIATSVLIFLGIPLMAGYLSRRFGEKVRGRGWYESKFLPAISPWALYG
LLFTIVILFALQGAQITSHPWDVARIALPLLAYFAIMWGGGYLLGASLGLGYARTTTLAFTAAGNNFELAIAVAIATYGA
TSGQALAGVVGPLIEVPVLVALVYVSLALRRRFDPETQHASHTEEDPNDDR

Sequences:

>Translated_371_residues
MSQATAARNADTTVGKLSTLDRYLPLWIGLAMAAGLLLGRNVPGLNSALEKVQVDGISLPIAVGLLIMMYPVLAKVRYDR
LGSVAGDRKLLAGSLVLNWVLGPALMFTLAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDRESAAVLVALNSLF
QVLTFAALGWFYLSVLPGWLHLPQTAITASPWEIATSVLIFLGIPLMAGYLSRRFGEKVRGRGWYESKFLPAISPWALYG
LLFTIVILFALQGAQITSHPWDVARIALPLLAYFAIMWGGGYLLGASLGLGYARTTTLAFTAAGNNFELAIAVAIATYGA
TSGQALAGVVGPLIEVPVLVALVYVSLALRRRFDPETQHASHTEEDPNDDR
>Mature_370_residues
SQATAARNADTTVGKLSTLDRYLPLWIGLAMAAGLLLGRNVPGLNSALEKVQVDGISLPIAVGLLIMMYPVLAKVRYDRL
GSVAGDRKLLAGSLVLNWVLGPALMFTLAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDRESAAVLVALNSLFQ
VLTFAALGWFYLSVLPGWLHLPQTAITASPWEIATSVLIFLGIPLMAGYLSRRFGEKVRGRGWYESKFLPAISPWALYGL
LFTIVILFALQGAQITSHPWDVARIALPLLAYFAIMWGGGYLLGASLGLGYARTTTLAFTAAGNNFELAIAVAIATYGAT
SGQALAGVVGPLIEVPVLVALVYVSLALRRRFDPETQHASHTEEDPNDDR

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=385, Percent_Identity=36.3636363636364, Blast_Score=194, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 39950; Mature: 39818

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQATAARNADTTVGKLSTLDRYLPLWIGLAMAAGLLLGRNVPGLNSALEKVQVDGISLP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
IAVGLLIMMYPVLAKVRYDRLGSVAGDRKLLAGSLVLNWVLGPALMFTLAWLLLPDLPEY
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
RTGLIIVGLARCIAMVIIWNDLACGDRESAAVLVALNSLFQVLTFAALGWFYLSVLPGWL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLPQTAITASPWEIATSVLIFLGIPLMAGYLSRRFGEKVRGRGWYESKFLPAISPWALYG
HCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LLFTIVILFALQGAQITSHPWDVARIALPLLAYFAIMWGGGYLLGASLGLGYARTTTLAF
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHEEEE
TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVALVYVSLALRRRFDPETQHA
EECCCCEEEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SHTEEDPNDDR
CCCCCCCCCCC
>Mature Secondary Structure 
SQATAARNADTTVGKLSTLDRYLPLWIGLAMAAGLLLGRNVPGLNSALEKVQVDGISLP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
IAVGLLIMMYPVLAKVRYDRLGSVAGDRKLLAGSLVLNWVLGPALMFTLAWLLLPDLPEY
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
RTGLIIVGLARCIAMVIIWNDLACGDRESAAVLVALNSLFQVLTFAALGWFYLSVLPGWL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLPQTAITASPWEIATSVLIFLGIPLMAGYLSRRFGEKVRGRGWYESKFLPAISPWALYG
HCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LLFTIVILFALQGAQITSHPWDVARIALPLLAYFAIMWGGGYLLGASLGLGYARTTTLAF
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHEEEE
TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVALVYVSLALRRRFDPETQHA
EECCCCEEEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SHTEEDPNDDR
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]