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The map label for this gene is yciL [C]

Identifier: 169629456

GI number: 169629456

Start: 2426017

End: 2426808

Strand: Direct

Name: yciL [C]

Synonym: MAB_2370

Alternate gene names: 169629456

Gene position: 2426017-2426808 (Clockwise)

Preceding gene: 169629455

Following gene: 169629457

Centisome position: 47.88

GC content: 63.26

Gene sequence:

>792_bases
GTGCTGGTTCTGGTGATGCTCCCGCTTTTACCGTTGATCAGGACTGAGACCATGAGCGAAGAAGGCATTCGGCTCCAGAA
GGTGTTGTCGCAAGCGGGTATTGCGTCACGCCGGGTTGCCGAAAGGATGATTTACGACGGTCGCGTCGAGGTGGACGGCG
AGATTGTCACCGAGCAGGGCAGACGAATCGACCCGGCTGTCAACGTGGTTCGCGTTGACGGTGCGCGTGTGATCATGAAC
ACCGATCTGGTGTATCTGGCTCTCAACAAGCCCTTCGGCATGCTGTCGACCATGTCGGACGACCGTGGCCGCCCCTGCGT
CGGCAAGCTGATCGAGGAACGGGTTCGGGGCAACCAGGGGGTGCGCAATGTCGGCCGTCTGGATGCCGACACCGTCGGGC
TGATCCTGCTCACCAACGACGGAGAGCTGACCCACCGGCTCATGCACCCGTCTTACGAGGTGCCTAAGACGTACATCGCG
ACCGTCGCCGGCACGATCCCGCGTGGCTTGGGGCGGCAGTTACGAGACGGCGTCGAGCTCGCCGACGGCCCGGCCAAGGT
GGACGAGTTCAAGTTCCTGGGCACCACGGACGGCCAGAGCATGGTGCAGCTGACGCTGCATGAGGGCCGCAATCGCATTG
TGCGACGCATGATGGACGCTGCCGGGCACCCGGTAGTGGAATTGGTGCGCACCAAGATCGGCGATGTGACGCTGGGCAAT
CAGCGCCCCGGGAGCCTACGTGCCCTGGGCCGCGATGAGATCGGCTCGCTGTACAAGGCGGTAGGACTGTGA

Upstream 100 bases:

>100_bases
ATCGCACCGCTGCTTCCCGATATCGATGTGATCGACGACCTATCCGAAAACCTCGGCGACGAGCCGCGGTTCGCGCGGCT
CAACCGGACAGCCGATAGCG

Downstream 100 bases:

>100_bases
CGCGCCTAGTGGTTGCCGTAGATGGCCCATCCGGTACCGGAAAGTCCTCCGTCGCAAAAGAATTGGCTCGTCAGCTAGGG
GCCTCATATCTCGATACCGG

Product: l RNA pseudouridine synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLVLVMLPLLPLIRTETMSEEGIRLQKVLSQAGIASRRVAERMIYDGRVEVDGEIVTEQGRRIDPAVNVVRVDGARVIMN
TDLVYLALNKPFGMLSTMSDDRGRPCVGKLIEERVRGNQGVRNVGRLDADTVGLILLTNDGELTHRLMHPSYEVPKTYIA
TVAGTIPRGLGRQLRDGVELADGPAKVDEFKFLGTTDGQSMVQLTLHEGRNRIVRRMMDAAGHPVVELVRTKIGDVTLGN
QRPGSLRALGRDEIGSLYKAVGL

Sequences:

>Translated_263_residues
MLVLVMLPLLPLIRTETMSEEGIRLQKVLSQAGIASRRVAERMIYDGRVEVDGEIVTEQGRRIDPAVNVVRVDGARVIMN
TDLVYLALNKPFGMLSTMSDDRGRPCVGKLIEERVRGNQGVRNVGRLDADTVGLILLTNDGELTHRLMHPSYEVPKTYIA
TVAGTIPRGLGRQLRDGVELADGPAKVDEFKFLGTTDGQSMVQLTLHEGRNRIVRRMMDAAGHPVVELVRTKIGDVTLGN
QRPGSLRALGRDEIGSLYKAVGL
>Mature_263_residues
MLVLVMLPLLPLIRTETMSEEGIRLQKVLSQAGIASRRVAERMIYDGRVEVDGEIVTEQGRRIDPAVNVVRVDGARVIMN
TDLVYLALNKPFGMLSTMSDDRGRPCVGKLIEERVRGNQGVRNVGRLDADTVGLILLTNDGELTHRLMHPSYEVPKTYIA
TVAGTIPRGLGRQLRDGVELADGPAKVDEFKFLGTTDGQSMVQLTLHEGRNRIVRRMMDAAGHPVVELVRTKIGDVTLGN
QRPGSLRALGRDEIGSLYKAVGL

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=226, Percent_Identity=42.4778761061947, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788510, Length=236, Percent_Identity=36.0169491525424, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790453, Length=246, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081838, Length=175, Percent_Identity=36.5714285714286, Blast_Score=98, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 28887; Mature: 28887

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLVMLPLLPLIRTETMSEEGIRLQKVLSQAGIASRRVAERMIYDGRVEVDGEIVTEQG
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCEEEECCC
RRIDPAVNVVRVDGARVIMNTDLVYLALNKPFGMLSTMSDDRGRPCVGKLIEERVRGNQG
CEECCCCEEEEECCEEEEEECCEEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCC
VRNVGRLDADTVGLILLTNDGELTHRLMHPSYEVPKTYIATVAGTIPRGLGRQLRDGVEL
HHHHCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
ADGPAKVDEFKFLGTTDGQSMVQLTLHEGRNRIVRRMMDAAGHPVVELVRTKIGDVTLGN
CCCCCCHHHEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEECC
QRPGSLRALGRDEIGSLYKAVGL
CCCCCHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLVLVMLPLLPLIRTETMSEEGIRLQKVLSQAGIASRRVAERMIYDGRVEVDGEIVTEQG
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCEEEECCC
RRIDPAVNVVRVDGARVIMNTDLVYLALNKPFGMLSTMSDDRGRPCVGKLIEERVRGNQG
CEECCCCEEEEECCEEEEEECCEEEEEECCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCC
VRNVGRLDADTVGLILLTNDGELTHRLMHPSYEVPKTYIATVAGTIPRGLGRQLRDGVEL
HHHHCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
ADGPAKVDEFKFLGTTDGQSMVQLTLHEGRNRIVRRMMDAAGHPVVELVRTKIGDVTLGN
CCCCCCHHHEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEECC
QRPGSLRALGRDEIGSLYKAVGL
CCCCCHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]