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The map label for this gene is xerD [H]

Identifier: 169629452

GI number: 169629452

Start: 2422458

End: 2423405

Strand: Direct

Name: xerD [H]

Synonym: MAB_2366

Alternate gene names: 169629452

Gene position: 2422458-2423405 (Clockwise)

Preceding gene: 169629451

Following gene: 169629453

Centisome position: 47.81

GC content: 68.57

Gene sequence:

>948_bases
GTGACGGCCGCGGTCGGGCTCCTTGACGGCGAGATCCAGTCCTACCTGGATCATCTCGACGTGGAACGCGGCGTCGCCGC
CAATACGCTGAGCTCCTACCGTCGGGACCTGCGCCGCTACCAGCAGCATCTCGCCGACCGCAAGATCGACCGGTTGGCCG
AGGTCTGCGAAACCGATGTCAGCGATTTCGTGGTCACGCTGCGCCGGGGCGATCCGGCGAACGGAGTGCCCGAGCTGTCC
GCGTCCTCGGCGGCCCGCGCATTGATCGCCGTGCGAGGGCTGCACCGGTTTGCCGCCATCGAGGGGCTGGCGCCCACGGA
TGTCGCCCGTGCGGTGAAACCGCCGACCCCCAACCGCCGGCTGCCGAAGAGCCTGACGGTCGAACAGGTGGAAGCACTGC
TGAATGCCGCGGGTGGCGGCGGCTCGGACGGACCACTGGATCTGCGCAACCGTGCACTGCTGGAGCTGCTGTACTCGACC
GGAGCACGCATCTCCGAGGCCGTGGGGCTGGACGTCGACGATGTGGATGTGCAGGCTCGTTCGGTGCTGCTGTGGGGCAA
GGGCGGCAAGCAGCGCCTGGTGCCGGTGGGTCGGCCTGCCGTAGAGGCGCTGCAGGCATACCTGGTGCGTGGCCGTCCCG
ATCTGGCACGCCGGGGACGCGGCGGCGTCCCCGCCCTGTTTCTGAACTCCCGGGGCGGACGGCTTTCCCGCCAGAGCGCA
TGGCAGGTGCTGGCCGACGCCGCCGAACGGGCCAAGATCAGCGCGGCGGTTTCCCCGCACACCCTGCGACATTCCTTTGC
GACACATCTGCTGGAGGGCGGCGCCGACGTTCGTGTTGTCCAGGAGTTACTCGGCCATGCGTCGGTGACAACGACCCAGA
TCTACACGTTGGTCACGGTCAGTGCGCTGCGCGAAGTATGGGCAGGTGCGCATCCCCGTGCCCGTTAG

Upstream 100 bases:

>100_bases
TTCTGGCCACGCATATCGCACTCGGGGGTCACCACACCCGGCCGGTGGACGCGCCCTGGCCGGACCGGCCCACGGCCTTC
GCGGAACGCAAGGCCGCAAC

Downstream 100 bases:

>100_bases
CAGTCGCCACATGCGCGGGTTGCCGCTACCGAAGGCCGCAACCCCACTAGACTTGCCCGAATGCCTTCGATGAGGCCCCC
GCATGCGGGAGCTACCACCA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTAAVGLLDGEIQSYLDHLDVERGVAANTLSSYRRDLRRYQQHLADRKIDRLAEVCETDVSDFVVTLRRGDPANGVPELS
ASSAARALIAVRGLHRFAAIEGLAPTDVARAVKPPTPNRRLPKSLTVEQVEALLNAAGGGGSDGPLDLRNRALLELLYST
GARISEAVGLDVDDVDVQARSVLLWGKGGKQRLVPVGRPAVEALQAYLVRGRPDLARRGRGGVPALFLNSRGGRLSRQSA
WQVLADAAERAKISAAVSPHTLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTLVTVSALREVWAGAHPRAR

Sequences:

>Translated_315_residues
MTAAVGLLDGEIQSYLDHLDVERGVAANTLSSYRRDLRRYQQHLADRKIDRLAEVCETDVSDFVVTLRRGDPANGVPELS
ASSAARALIAVRGLHRFAAIEGLAPTDVARAVKPPTPNRRLPKSLTVEQVEALLNAAGGGGSDGPLDLRNRALLELLYST
GARISEAVGLDVDDVDVQARSVLLWGKGGKQRLVPVGRPAVEALQAYLVRGRPDLARRGRGGVPALFLNSRGGRLSRQSA
WQVLADAAERAKISAAVSPHTLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTLVTVSALREVWAGAHPRAR
>Mature_314_residues
TAAVGLLDGEIQSYLDHLDVERGVAANTLSSYRRDLRRYQQHLADRKIDRLAEVCETDVSDFVVTLRRGDPANGVPELSA
SSAARALIAVRGLHRFAAIEGLAPTDVARAVKPPTPNRRLPKSLTVEQVEALLNAAGGGGSDGPLDLRNRALLELLYSTG
ARISEAVGLDVDDVDVQARSVLLWGKGGKQRLVPVGRPAVEALQAYLVRGRPDLARRGRGGVPALFLNSRGGRLSRQSAW
QVLADAAERAKISAAVSPHTLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTLVTVSALREVWAGAHPRAR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=304, Percent_Identity=41.7763157894737, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1790244, Length=308, Percent_Identity=35.7142857142857, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI1790767, Length=193, Percent_Identity=31.0880829015544, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790768, Length=186, Percent_Identity=31.1827956989247, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33805; Mature: 33674

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVGLLDGEIQSYLDHLDVERGVAANTLSSYRRDLRRYQQHLADRKIDRLAEVCETDV
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SDFVVTLRRGDPANGVPELSASSAARALIAVRGLHRFAAIEGLAPTDVARAVKPPTPNRR
HHHEEHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
LPKSLTVEQVEALLNAAGGGGSDGPLDLRNRALLELLYSTGARISEAVGLDVDDVDVQAR
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCEE
SVLLWGKGGKQRLVPVGRPAVEALQAYLVRGRPDLARRGRGGVPALFLNSRGGRLSRQSA
EEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCHHHHH
WQVLADAAERAKISAAVSPHTLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTLVTV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
SALREVWAGAHPRAR
HHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAAVGLLDGEIQSYLDHLDVERGVAANTLSSYRRDLRRYQQHLADRKIDRLAEVCETDV
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SDFVVTLRRGDPANGVPELSASSAARALIAVRGLHRFAAIEGLAPTDVARAVKPPTPNRR
HHHEEHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
LPKSLTVEQVEALLNAAGGGGSDGPLDLRNRALLELLYSTGARISEAVGLDVDDVDVQAR
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCEE
SVLLWGKGGKQRLVPVGRPAVEALQAYLVRGRPDLARRGRGGVPALFLNSRGGRLSRQSA
EEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCCHHHHH
WQVLADAAERAKISAAVSPHTLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTLVTV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
SALREVWAGAHPRAR
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]