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The map label for this gene is argD [H]

Identifier: 169629425

GI number: 169629425

Start: 2394151

End: 2395353

Strand: Direct

Name: argD [H]

Synonym: MAB_2339

Alternate gene names: 169629425

Gene position: 2394151-2395353 (Clockwise)

Preceding gene: 169629424

Following gene: 169629426

Centisome position: 47.25

GC content: 66.58

Gene sequence:

>1203_bases
GTGACCGAAGCACCAGACAGCACCTCCCGGGCACAGCAGCGCTGGGAGCACGTCATGATGAACAACTACGGCACACCGCC
GATTGTTCTCGCCGAGGGCGAGGGCGCCGTGGTTACCGACGTTGACGGCAAGCGGTATCTGGATCTATTGGGCGGTATCG
CGGTCAATGTGCTGGGGCACCGCAACCAATCAGTCATCGACGCCGTCACCCAACAGCTCTCCACCCTGGGCCACACGTCG
AATCTGTACGCGACAGGGCCGGCCATCGAACTCTCCGAGGCGCTGGTCGCCCGGCTGGGGGTGCCCGGCAGGGTCTTTCT
CTGCAACTCCGGCACCGAGGCCAACGAGGCCGCCTTCAAACTGACCCGTCTTACCGGTCGCACCAAAGTCGTAGCGGCCG
AAGGGGCTTTCCACGGCCGGACCATGGGATCGCTGGCGCTCACCGGCCAGCCGGCCAAACAGGCACCATTCGAACCGCTA
CCGGCGGGTGTGCTCCATGTGCCGTACGGCGATCTCGCCGCCATAGAGGCTGCTGTCGACGGTGACACGGCCGCCGTGTT
CCTGGAGCCGATCATGGGTGAGGGCGGCGTGGTCGTGCCACCGGAGGGCTACCTGGCGGGGGTGCGCGAGATCACCGCAC
GCCATGGCGCGCTCCTGGTGCTCGACGAGGTGCAGACCGGAATCGGCCGCACCGGAACGTTCTTCGCGCATCAGCAGGCC
GGTATCACCCCTGATGTCGTCACCCTGGCCAAGGGCCTGGGCGGAGGGCTCCCCATCGGGGCATGCATCGCCACCGGCGC
GGCAGCCGACTTACTCACCCCTGGCATGCACGGCAGCACGTTCGGCGGCAATCCGGTCTGCGTGGCAGCGGCATTGGCGG
TGCTGCGCGTGCTCGACGAACAGGACCTTGTCGACCATGCCGCCGCGGCGGGCAAGTCATTGAGTCATTCCGTTGAAGAA
CTCAACCATCCGTTGGTCGATCGGGTGCGCGGTGCGGGACTGCTTCTCGGCATCGTCTTGACGGAGCAACGCGCCAAGGC
CGCCGAGACGGCCGCGCGCGAGGCCGGGTTCCTCGTCAACGCCGCCGCACCCGATGTGCTGCGGCTGGCGCCACCGCTGA
TCATCACCGATGAACAAATCGGGGAATTTGTCACCGCGCTGCCGGGAATCCTCGACACCGCCGCAGAACAGGAGCAGGCA
TGA

Upstream 100 bases:

>100_bases
GGGTGCCCAGCGCCCACATCATCGACGGGCGTGTCGAGCATTGCGTGCTGGTCGAACTGTTCACCGACGAGGGCGTCGGG
ACAATCATCAGGAGTAAGTC

Downstream 100 bases:

>100_bases
TTCAGTCGAAGTCACTTCGCCATTTTCTGAGGGACGACGACCTCTCACCTGCCGAACAGGCCGAAGTCCTCACGTTGGCA
GCCGAACTCAAGAAGGCGCC

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTEAPDSTSRAQQRWEHVMMNNYGTPPIVLAEGEGAVVTDVDGKRYLDLLGGIAVNVLGHRNQSVIDAVTQQLSTLGHTS
NLYATGPAIELSEALVARLGVPGRVFLCNSGTEANEAAFKLTRLTGRTKVVAAEGAFHGRTMGSLALTGQPAKQAPFEPL
PAGVLHVPYGDLAAIEAAVDGDTAAVFLEPIMGEGGVVVPPEGYLAGVREITARHGALLVLDEVQTGIGRTGTFFAHQQA
GITPDVVTLAKGLGGGLPIGACIATGAAADLLTPGMHGSTFGGNPVCVAAALAVLRVLDEQDLVDHAAAAGKSLSHSVEE
LNHPLVDRVRGAGLLLGIVLTEQRAKAAETAAREAGFLVNAAAPDVLRLAPPLIITDEQIGEFVTALPGILDTAAEQEQA

Sequences:

>Translated_400_residues
MTEAPDSTSRAQQRWEHVMMNNYGTPPIVLAEGEGAVVTDVDGKRYLDLLGGIAVNVLGHRNQSVIDAVTQQLSTLGHTS
NLYATGPAIELSEALVARLGVPGRVFLCNSGTEANEAAFKLTRLTGRTKVVAAEGAFHGRTMGSLALTGQPAKQAPFEPL
PAGVLHVPYGDLAAIEAAVDGDTAAVFLEPIMGEGGVVVPPEGYLAGVREITARHGALLVLDEVQTGIGRTGTFFAHQQA
GITPDVVTLAKGLGGGLPIGACIATGAAADLLTPGMHGSTFGGNPVCVAAALAVLRVLDEQDLVDHAAAAGKSLSHSVEE
LNHPLVDRVRGAGLLLGIVLTEQRAKAAETAAREAGFLVNAAAPDVLRLAPPLIITDEQIGEFVTALPGILDTAAEQEQA
>Mature_399_residues
TEAPDSTSRAQQRWEHVMMNNYGTPPIVLAEGEGAVVTDVDGKRYLDLLGGIAVNVLGHRNQSVIDAVTQQLSTLGHTSN
LYATGPAIELSEALVARLGVPGRVFLCNSGTEANEAAFKLTRLTGRTKVVAAEGAFHGRTMGSLALTGQPAKQAPFEPLP
AGVLHVPYGDLAAIEAAVDGDTAAVFLEPIMGEGGVVVPPEGYLAGVREITARHGALLVLDEVQTGIGRTGTFFAHQQAG
ITPDVVTLAKGLGGGLPIGACIATGAAADLLTPGMHGSTFGGNPVCVAAALAVLRVLDEQDLVDHAAAAGKSLSHSVEEL
NHPLVDRVRGAGLLLGIVLTEQRAKAAETAAREAGFLVNAAAPDVLRLAPPLIITDEQIGEFVTALPGILDTAAEQEQA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=396, Percent_Identity=35.6060606060606, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI284507298, Length=290, Percent_Identity=40, Blast_Score=200, Evalue=1e-51,
Organism=Homo sapiens, GI13994255, Length=414, Percent_Identity=31.1594202898551, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=29.1866028708134, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI24119277, Length=415, Percent_Identity=30.8433734939759, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=28.7081339712919, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI226442709, Length=383, Percent_Identity=29.7650130548303, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI188536080, Length=432, Percent_Identity=24.7685185185185, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679950, Length=432, Percent_Identity=24.7685185185185, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679946, Length=432, Percent_Identity=24.7685185185185, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=40.6824146981627, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789759, Length=391, Percent_Identity=39.6419437340153, Blast_Score=284, Evalue=6e-78,
Organism=Escherichia coli, GI145693181, Length=368, Percent_Identity=41.5760869565217, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1789016, Length=430, Percent_Identity=34.1860465116279, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1787560, Length=381, Percent_Identity=35.1706036745407, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786349, Length=343, Percent_Identity=30.9037900874636, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786991, Length=394, Percent_Identity=29.4416243654822, Blast_Score=118, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=372, Percent_Identity=36.8279569892473, Blast_Score=241, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI25144274, Length=363, Percent_Identity=33.8842975206612, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI32564660, Length=414, Percent_Identity=30.1932367149758, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71992977, Length=422, Percent_Identity=29.6208530805687, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17541228, Length=413, Percent_Identity=26.1501210653753, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=161, Percent_Identity=33.5403726708075, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=35.969387755102, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6323470, Length=424, Percent_Identity=34.4339622641509, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6321456, Length=432, Percent_Identity=24.3055555555556, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357415, Length=377, Percent_Identity=35.8090185676393, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI28574759, Length=406, Percent_Identity=31.5270935960591, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI161085790, Length=413, Percent_Identity=31.2348668280872, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=29.8578199052133, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI281366494, Length=426, Percent_Identity=25.1173708920188, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667139, Length=426, Percent_Identity=25.1173708920188, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667143, Length=426, Percent_Identity=25.1173708920188, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41140; Mature: 41009

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAPDSTSRAQQRWEHVMMNNYGTPPIVLAEGEGAVVTDVDGKRYLDLLGGIAVNVLGH
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCC
RNQSVIDAVTQQLSTLGHTSNLYATGPAIELSEALVARLGVPGRVFLCNSGTEANEAAFK
CCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHEE
LTRLTGRTKVVAAEGAFHGRTMGSLALTGQPAKQAPFEPLPAGVLHVPYGDLAAIEAAVD
EEEECCCEEEEEECCCCCCCCCCCEEECCCCHHCCCCCCCCCCEEECCCCCHHHHHHHCC
GDTAAVFLEPIMGEGGVVVPPEGYLAGVREITARHGALLVLDEVQTGIGRTGTFFAHQQA
CCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHCCCEEEEEECHHHCCCCCCEEEEECCC
GITPDVVTLAKGLGGGLPIGACIATGAAADLLTPGMHGSTFGGNPVCVAAALAVLRVLDE
CCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCH
QDLVDHAAAAGKSLSHSVEELNHPLVDRVRGAGLLLGIVLTEQRAKAAETAAREAGFLVN
HHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEE
AAAPDVLRLAPPLIITDEQIGEFVTALPGILDTAAEQEQA
CCCCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEAPDSTSRAQQRWEHVMMNNYGTPPIVLAEGEGAVVTDVDGKRYLDLLGGIAVNVLGH
CCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCC
RNQSVIDAVTQQLSTLGHTSNLYATGPAIELSEALVARLGVPGRVFLCNSGTEANEAAFK
CCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHEE
LTRLTGRTKVVAAEGAFHGRTMGSLALTGQPAKQAPFEPLPAGVLHVPYGDLAAIEAAVD
EEEECCCEEEEEECCCCCCCCCCCEEECCCCHHCCCCCCCCCCEEECCCCCHHHHHHHCC
GDTAAVFLEPIMGEGGVVVPPEGYLAGVREITARHGALLVLDEVQTGIGRTGTFFAHQQA
CCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHCCCEEEEEECHHHCCCCCCEEEEECCC
GITPDVVTLAKGLGGGLPIGACIATGAAADLLTPGMHGSTFGGNPVCVAAALAVLRVLDE
CCCHHHHHHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCH
QDLVDHAAAAGKSLSHSVEELNHPLVDRVRGAGLLLGIVLTEQRAKAAETAAREAGFLVN
HHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEE
AAAPDVLRLAPPLIITDEQIGEFVTALPGILDTAAEQEQA
CCCCCHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA