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The map label for this gene is argB [H]

Identifier: 169629424

GI number: 169629424

Start: 2393273

End: 2394154

Strand: Direct

Name: argB [H]

Synonym: MAB_2338

Alternate gene names: 169629424

Gene position: 2393273-2394154 (Clockwise)

Preceding gene: 169629423

Following gene: 169629425

Centisome position: 47.23

GC content: 63.15

Gene sequence:

>882_bases
GTGAAGGCAACCAAGAAGGCCACGAAAAAGGCCGCTGTGCTGGCGGGCGCGCTCCCGTGGCTCAAGAAGCTGCACGGCAC
CATCGTCGTCATCAAGTACGGCGGTAACGCGATGACCGACGACGCGCTGAAGAACGCCTTCGCCGAAGACATGGTGTTTC
TGCGCAACTGTGGTATCCACCCGGTCGTCGTGCACGGCGGAGGCCCGCAGATCAGCGCGATGCTGAAAAAACTCGGTGTC
GACGGTGAATTCAAGGGTGGGTTCCGCGTCACCACGCCGGAGGTGCTCGATATCGCGCGCATGGTGCTATTCGGCCAGGT
TGGCCGCGAGTTGGTCGGATTGATCAACAGCCACGGACCGTATGCGGTCGGGATCACGGGTGAGGACGCGCAGCTGTTCA
CGGCCGTCCGGCGCACCGCGACGGTGGATGGAGTCGAGACCGATATCGGATTGGTCGGTGATGTCGCACAGGTGAGTCCC
GAGGCTATTCTCGACCTGATCGACGCCGGCCGTATCCCGGTGGTCTCGACGGTGGCGCCGGATGCGGACGGCGTGGTACA
CAACCTGAACGCCGATACAGCAGCCGGTGCGCTCGCGGAAGCCCTTGGCGCCGAACGTCTCCTGATGCTCACCGACATCG
AAGGCCTGTACACAGACTGGCCGGACCGAGAGTCCTTGGTCACGGAGATCGCGGCCGAAGATCTGCGGTCGCTGCTACCG
AAGCTGGAATCGGGGATGATCCCGAAGATCGAGGCTTGCTTGCGAGCCGTCGACGGTGGGGTGCCCAGCGCCCACATCAT
CGACGGGCGTGTCGAGCATTGCGTGCTGGTCGAACTGTTCACCGACGAGGGCGTCGGGACAATCATCAGGAGTAAGTCGT
GA

Upstream 100 bases:

>100_bases
TCGAGGTACTCATCGACCTTGGTGCCGGAGACCGGTCGGCAACCATCCGCACCACCGATCTGTCGCACGCCTATGTCGAA
GAGAACTCGGCGTACAGCTC

Downstream 100 bases:

>100_bases
CCGAAGCACCAGACAGCACCTCCCGGGCACAGCAGCGCTGGGAGCACGTCATGATGAACAACTACGGCACACCGCCGATT
GTTCTCGCCGAGGGCGAGGG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKATKKATKKAAVLAGALPWLKKLHGTIVVIKYGGNAMTDDALKNAFAEDMVFLRNCGIHPVVVHGGGPQISAMLKKLGV
DGEFKGGFRVTTPEVLDIARMVLFGQVGRELVGLINSHGPYAVGITGEDAQLFTAVRRTATVDGVETDIGLVGDVAQVSP
EAILDLIDAGRIPVVSTVAPDADGVVHNLNADTAAGALAEALGAERLLMLTDIEGLYTDWPDRESLVTEIAAEDLRSLLP
KLESGMIPKIEACLRAVDGGVPSAHIIDGRVEHCVLVELFTDEGVGTIIRSKS

Sequences:

>Translated_293_residues
MKATKKATKKAAVLAGALPWLKKLHGTIVVIKYGGNAMTDDALKNAFAEDMVFLRNCGIHPVVVHGGGPQISAMLKKLGV
DGEFKGGFRVTTPEVLDIARMVLFGQVGRELVGLINSHGPYAVGITGEDAQLFTAVRRTATVDGVETDIGLVGDVAQVSP
EAILDLIDAGRIPVVSTVAPDADGVVHNLNADTAAGALAEALGAERLLMLTDIEGLYTDWPDRESLVTEIAAEDLRSLLP
KLESGMIPKIEACLRAVDGGVPSAHIIDGRVEHCVLVELFTDEGVGTIIRSKS
>Mature_293_residues
MKATKKATKKAAVLAGALPWLKKLHGTIVVIKYGGNAMTDDALKNAFAEDMVFLRNCGIHPVVVHGGGPQISAMLKKLGV
DGEFKGGFRVTTPEVLDIARMVLFGQVGRELVGLINSHGPYAVGITGEDAQLFTAVRRTATVDGVETDIGLVGDVAQVSP
EAILDLIDAGRIPVVSTVAPDADGVVHNLNADTAAGALAEALGAERLLMLTDIEGLYTDWPDRESLVTEIAAEDLRSLLP
KLESGMIPKIEACLRAVDGGVPSAHIIDGRVEHCVLVELFTDEGVGTIIRSKS

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI145693208, Length=232, Percent_Identity=32.3275862068966, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789181, Length=285, Percent_Identity=25.2631578947368, Blast_Score=74, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320913, Length=266, Percent_Identity=29.3233082706767, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 30847; Mature: 30847

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATKKATKKAAVLAGALPWLKKLHGTIVVIKYGGNAMTDDALKNAFAEDMVFLRNCGIH
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
PVVVHGGGPQISAMLKKLGVDGEFKGGFRVTTPEVLDIARMVLFGQVGRELVGLINSHGP
EEEEECCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YAVGITGEDAQLFTAVRRTATVDGVETDIGLVGDVAQVSPEAILDLIDAGRIPVVSTVAP
EEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCEEEECCC
DADGVVHNLNADTAAGALAEALGAERLLMLTDIEGLYTDWPDRESLVTEIAAEDLRSLLP
CCCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHH
KLESGMIPKIEACLRAVDGGVPSAHIIDGRVEHCVLVELFTDEGVGTIIRSKS
HHHCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEEEEEEECCCCCCCEEECCC
>Mature Secondary Structure
MKATKKATKKAAVLAGALPWLKKLHGTIVVIKYGGNAMTDDALKNAFAEDMVFLRNCGIH
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
PVVVHGGGPQISAMLKKLGVDGEFKGGFRVTTPEVLDIARMVLFGQVGRELVGLINSHGP
EEEEECCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YAVGITGEDAQLFTAVRRTATVDGVETDIGLVGDVAQVSPEAILDLIDAGRIPVVSTVAP
EEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCEEEECCC
DADGVVHNLNADTAAGALAEALGAERLLMLTDIEGLYTDWPDRESLVTEIAAEDLRSLLP
CCCCEEEECCCCHHHHHHHHHHCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHH
KLESGMIPKIEACLRAVDGGVPSAHIIDGRVEHCVLVELFTDEGVGTIIRSKS
HHHCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEEEEEEECCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA