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The map label for this gene is argC

Identifier: 169629422

GI number: 169629422

Start: 2391022

End: 2392065

Strand: Direct

Name: argC

Synonym: MAB_2336

Alternate gene names: 169629422

Gene position: 2391022-2392065 (Clockwise)

Preceding gene: 169629421

Following gene: 169629423

Centisome position: 47.19

GC content: 67.43

Gene sequence:

>1044_bases
ATGACTACTGGGTTCTCGGTCGCGGTCGCCGGTGCCAGCGGATATGCAGGCGGGGAAATCCTGCGCCTGCTGCTGGCACA
TCCGGCGTACACCGCGGGCCGTCTGCGTATCGGAGTGCTGACCGCCGGTTCGAACGCCGGCAGCAGCCTCATCGAGCACC
ACCCGAATCTGACGCCGCTCGCTGACCACAAACTACAGCCCACCGATTCCACGCTGTTGCGGGGGCATGACGTGGTTTTC
CTGGCGTTACCGCATGGATCTTCGGCAAAGATCGCCGAGGAACTGGGCCCGCAGACCCTCATCATCGACTGCGGTGCCGA
TTTCCGGCTGACCGATGCCGCGGCATGGGAGCGTTACTACGGGTCAAAGCACGCGGGAAGCTGGCCGTACGGGCTGCCTG
AGCTTCCGGGCGGCCGGGATGCGCTGCATGGCACCAAGCGCGTCGCGGTGCCGGGCTGTTACCCGACTGCGGCACTGCTG
GCCCTGTCGCCCGCGGTGACCGCCGGTTTGGTGGAGCCATCGGTCACGGTGGTGGCGGTGAGCGGCACCACCGGTGCGGG
CCGCGCCCCCAAGGCCGAGCTACTTGCCTCCGAGGTGATGGGGTCGGCTCGCGCGTACAACATCGCCGGCGCCCACCGGC
ATACCCCTGAAATCGCTCAGGGGCTCAAGCATCCGTCGGGTGGTCCGGTGAGCGTGTCGTTCACGCCGGTTCTCATCCCG
ATGCCCCGCGGCATTCTCGCCACCTGTACGGCGCCGACCACGGCCTCCCTGTCGGAGATACGCGACGCTTACGAGGACGC
TTATCGGACCGAAGAGTTCATTCACGTGCTGCCCGAGGGGCACTTGCCCACCACGAAGGCGGTGGTGGGGAGCAACGCGG
TACACATCGGACTCGCGGTCGACCCCGATGCCGGTGTGCTGGTTGCCGTCGCCGCTATCGACAACCTGGTCAAGGGCACC
GCGGGTGCCGCAATCCAGTCCATGAACCTCGCCCTCGGCTGGCCCGAGGCCGACGGGCTGTCCATCGTGGGAGTGGCGCC
GTGA

Upstream 100 bases:

>100_bases
CGCATTACACCGTTTAGCTCAAGTTGAGGTTGACCGGCGGTGGCCGAAGGCTTGCCGAATATATTTGCGCTCTTGTGCAT
AATGATACAGAATTGGTCTC

Downstream 100 bases:

>100_bases
CCAACGAAACTGTGATCTCACGGCTCGTGCGCACGCAAGGCGTCACCGCACCCGCGGGCTTCAAGGCCGCCGGAATCAGC
GCTGGTATCAAGGCTTCCGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTTGFSVAVAGASGYAGGEILRLLLAHPAYTAGRLRIGVLTAGSNAGSSLIEHHPNLTPLADHKLQPTDSTLLRGHDVVF
LALPHGSSAKIAEELGPQTLIIDCGADFRLTDAAAWERYYGSKHAGSWPYGLPELPGGRDALHGTKRVAVPGCYPTAALL
ALSPAVTAGLVEPSVTVVAVSGTTGAGRAPKAELLASEVMGSARAYNIAGAHRHTPEIAQGLKHPSGGPVSVSFTPVLIP
MPRGILATCTAPTTASLSEIRDAYEDAYRTEEFIHVLPEGHLPTTKAVVGSNAVHIGLAVDPDAGVLVAVAAIDNLVKGT
AGAAIQSMNLALGWPEADGLSIVGVAP

Sequences:

>Translated_347_residues
MTTGFSVAVAGASGYAGGEILRLLLAHPAYTAGRLRIGVLTAGSNAGSSLIEHHPNLTPLADHKLQPTDSTLLRGHDVVF
LALPHGSSAKIAEELGPQTLIIDCGADFRLTDAAAWERYYGSKHAGSWPYGLPELPGGRDALHGTKRVAVPGCYPTAALL
ALSPAVTAGLVEPSVTVVAVSGTTGAGRAPKAELLASEVMGSARAYNIAGAHRHTPEIAQGLKHPSGGPVSVSFTPVLIP
MPRGILATCTAPTTASLSEIRDAYEDAYRTEEFIHVLPEGHLPTTKAVVGSNAVHIGLAVDPDAGVLVAVAAIDNLVKGT
AGAAIQSMNLALGWPEADGLSIVGVAP
>Mature_346_residues
TTGFSVAVAGASGYAGGEILRLLLAHPAYTAGRLRIGVLTAGSNAGSSLIEHHPNLTPLADHKLQPTDSTLLRGHDVVFL
ALPHGSSAKIAEELGPQTLIIDCGADFRLTDAAAWERYYGSKHAGSWPYGLPELPGGRDALHGTKRVAVPGCYPTAALLA
LSPAVTAGLVEPSVTVVAVSGTTGAGRAPKAELLASEVMGSARAYNIAGAHRHTPEIAQGLKHPSGGPVSVSFTPVLIPM
PRGILATCTAPTTASLSEIRDAYEDAYRTEEFIHVLPEGHLPTTKAVVGSNAVHIGLAVDPDAGVLVAVAAIDNLVKGTA
GAAIQSMNLALGWPEADGLSIVGVAP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=351, Percent_Identity=36.4672364672365, Blast_Score=154, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6320913, Length=352, Percent_Identity=28.6931818181818, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_MYCA9 (B1MAZ6)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703071.1
- ProteinModelPortal:   B1MAZ6
- SMR:   B1MAZ6
- EnsemblBacteria:   EBMYCT00000004602
- GeneID:   5964846
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2336
- GeneTree:   EBGT00050000015828
- HOGENOM:   HBG294213
- OMA:   MTHINAV
- ProtClustDB:   PRK00436
- BioCyc:   MABS561007:MAB_2336-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 35441; Mature: 35310

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 153-153

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGFSVAVAGASGYAGGEILRLLLAHPAYTAGRLRIGVLTAGSNAGSSLIEHHPNLTPL
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHCCCCCCC
ADHKLQPTDSTLLRGHDVVFLALPHGSSAKIAEELGPQTLIIDCGADFRLTDAAAWERYY
CCCCCCCCCCHHCCCCCEEEEEECCCCCCHHHHHCCCCEEEEECCCCCEECHHHHHHHHC
GSKHAGSWPYGLPELPGGRDALHGTKRVAVPGCYPTAALLALSPAVTAGLVEPSVTVVAV
CCCCCCCCCCCCCCCCCCCHHHCCCCEEECCCCCHHHHHHHHCHHHHHHCCCCCEEEEEE
SGTTGAGRAPKAELLASEVMGSARAYNIAGAHRHTPEIAQGLKHPSGGPVSVSFTPVLIP
ECCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCEEEEEEEEEEEE
MPRGILATCTAPTTASLSEIRDAYEDAYRTEEFIHVLPEGHLPTTKAVVGSNAVHIGLAV
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHCCCEEEEEEEE
DPDAGVLVAVAAIDNLVKGTAGAAIQSMNLALGWPEADGLSIVGVAP
CCCCCEEEEHHHHHHHHHCCCCHHEEECEEEEECCCCCCEEEEEECC
>Mature Secondary Structure 
TTGFSVAVAGASGYAGGEILRLLLAHPAYTAGRLRIGVLTAGSNAGSSLIEHHPNLTPL
CCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHCCCCCCC
ADHKLQPTDSTLLRGHDVVFLALPHGSSAKIAEELGPQTLIIDCGADFRLTDAAAWERYY
CCCCCCCCCCHHCCCCCEEEEEECCCCCCHHHHHCCCCEEEEECCCCCEECHHHHHHHHC
GSKHAGSWPYGLPELPGGRDALHGTKRVAVPGCYPTAALLALSPAVTAGLVEPSVTVVAV
CCCCCCCCCCCCCCCCCCCHHHCCCCEEECCCCCHHHHHHHHCHHHHHHCCCCCEEEEEE
SGTTGAGRAPKAELLASEVMGSARAYNIAGAHRHTPEIAQGLKHPSGGPVSVSFTPVLIP
ECCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCEEEEEEEEEEEE
MPRGILATCTAPTTASLSEIRDAYEDAYRTEEFIHVLPEGHLPTTKAVVGSNAVHIGLAV
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHCCCEEEEEEEE
DPDAGVLVAVAAIDNLVKGTAGAAIQSMNLALGWPEADGLSIVGVAP
CCCCCEEEEHHHHHHHHHCCCCHHEEECEEEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA