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The map label for this gene is mtb12 [H]

Identifier: 169629247

GI number: 169629247

Start: 2175299

End: 2175826

Strand: Reverse

Name: mtb12 [H]

Synonym: MAB_2161c

Alternate gene names: 169629247

Gene position: 2175826-2175299 (Counterclockwise)

Preceding gene: 169629255

Following gene: 169629246

Centisome position: 42.94

GC content: 66.29

Gene sequence:

>528_bases
ATGACGGGGGTCGCCATGCTGGGTTTACTCGCGGCCGTGGCGGTTGGCTCGGCAGTGCCGACGGGCGAGCCGACAGCCAG
CTCTGCTAGCCCAACAGCAACGACCGTGACGTCCTTCACCATCGCCCCCGCGTCATGGGATGTGCCCCTGGATGTGCCCG
CCGAGCCCGCCGACGGGACACCCACGCCCGACGAGCTGAGCGGTTTGCTGTATTCGCTCGCCGATCCGGGCGTGTCGGCG
CTCGCCAAGGGCGGTCTGGTGGAGGGCGGCATCGGTGCCGGGGAAGCCATCTATGCCGATCGCGCCTTCAAGAACGCCAA
CCGTGACGGGTTCCTGCCGCTGGCCTTCACCGTGTCCAACGTCAAGTCCACCGGGCCAGGCCTCGCCGCGGCCGCGGTCA
CCATTACCGGCCCCAAAACCCAGGCCTACACCACCAACATCAACTTCGTGGATCAGGACGGCTGGAAGATCAGCAAGGCC
TCGGCCATTTCGCTGATTCAGGCAGCATCCGGTAAGTCTGGAAGGTAG

Upstream 100 bases:

>100_bases
CTACGCGTGCGGGGTCTACCCGTTCATGGGGACGTCTACGCTGTTAGCGTTCGTCACATTCAGGCCGATCGAAAGGACAA
CCGTGAGCTCACGAACCGGT

Downstream 100 bases:

>100_bases
ACGTGGATGAGGAGGATTGGACGATCTCCAAAACCTCACTCGCCGATATCGTCACCGCACTTGGCCGAATGACTTAGCCG
ATACGCCGAATGGGAGTCAC

Product: low molecular weight antigen Mtb12

Products: NA

Alternate protein names: CFP-2; Low molecular weight protein antigen 2 [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTGVAMLGLLAAVAVGSAVPTGEPTASSASPTATTVTSFTIAPASWDVPLDVPAEPADGTPTPDELSGLLYSLADPGVSA
LAKGGLVEGGIGAGEAIYADRAFKNANRDGFLPLAFTVSNVKSTGPGLAAAAVTITGPKTQAYTTNINFVDQDGWKISKA
SAISLIQAASGKSGR

Sequences:

>Translated_175_residues
MTGVAMLGLLAAVAVGSAVPTGEPTASSASPTATTVTSFTIAPASWDVPLDVPAEPADGTPTPDELSGLLYSLADPGVSA
LAKGGLVEGGIGAGEAIYADRAFKNANRDGFLPLAFTVSNVKSTGPGLAAAAVTITGPKTQAYTTNINFVDQDGWKISKA
SAISLIQAASGKSGR
>Mature_174_residues
TGVAMLGLLAAVAVGSAVPTGEPTASSASPTATTVTSFTIAPASWDVPLDVPAEPADGTPTPDELSGLLYSLADPGVSAL
AKGGLVEGGIGAGEAIYADRAFKNANRDGFLPLAFTVSNVKSTGPGLAAAAVTITGPKTQAYTTNINFVDQDGWKISKAS
AISLIQAASGKSGR

Specific function: May play a role in the development of protective immune responses [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTB12 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020235
- ProDom:   PD033474 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17307; Mature: 17175

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVAMLGLLAAVAVGSAVPTGEPTASSASPTATTVTSFTIAPASWDVPLDVPAEPADGT
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCC
PTPDELSGLLYSLADPGVSALAKGGLVEGGIGAGEAIYADRAFKNANRDGFLPLAFTVSN
CCHHHHHHHHHHHCCCCHHHHHCCCCEECCCCCCCEEEHHHHHHCCCCCCCEEEEEEECC
VKSTGPGLAAAAVTITGPKTQAYTTNINFVDQDGWKISKASAISLIQAASGKSGR
CCCCCCCCEEEEEEEECCCCEEEEECCEEEECCCCEECHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TGVAMLGLLAAVAVGSAVPTGEPTASSASPTATTVTSFTIAPASWDVPLDVPAEPADGT
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCC
PTPDELSGLLYSLADPGVSALAKGGLVEGGIGAGEAIYADRAFKNANRDGFLPLAFTVSN
CCHHHHHHHHHHHCCCCHHHHHCCCCEECCCCCCCEEEHHHHHHCCCCCCCEEEEEEECC
VKSTGPGLAAAAVTITGPKTQAYTTNINFVDQDGWKISKASAISLIQAASGKSGR
CCCCCCCCEEEEEEEECCCCEEEEECCEEEECCCCEECHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]