| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is penA [H]
Identifier: 169629087
GI number: 169629087
Start: 1996666
End: 1998594
Strand: Direct
Name: penA [H]
Synonym: MAB_2000
Alternate gene names: 169629087
Gene position: 1996666-1998594 (Clockwise)
Preceding gene: 169629086
Following gene: 169629088
Centisome position: 39.4
GC content: 64.07
Gene sequence:
>1929_bases GTGAACCGGCAGGATCGGTCCCGGCCGGTCGGCGCCCGTCGCACCCGGCGGCCGGCCGCTGCCGTTTCGCGGACGGCAGG GTTCGCCTTTCGCCACCGCACGGGCAACATCATCATTTTCTTGACCTTGGCCATCGCGGCCATTCAGCTGTTCACCCTGC AGGGCCCGCGTGCGGCGGGTCTGCGTGCGGAGGCCTCGGGGCAGCTCAAGGTCACCGAGACCGAGAAGGCGCTGCGCGGC ACGATCGTGGACCGTGCGGGCAACAAGTTGGCGTTCACCATCGAGGCTCGCGCACTGACTTTCCAGCCGAAGAAGATCCG CGAACAACTCAACAAGGCGTGGGAGAAGAGCCAAGAGATCCTCAAGGATCCCGGGAAGAGTGACGCCGATAAGGCTGCTG CGGCGAAAATCAGGTCCGTCGAGCCCGAGCGCCGGCTGCAGGACATCGCCAATGGGGTTTCGGCCAAGCTGGGTAACAAA CCCGACGCCAAGAGTCTGCTGAAGAAGATCCGCAGTGATGACACCTTCGCCTACCTGGCGCGCTCGGTCGACCCGGGTAT CGCCGCCCAGATAACCAAGGAGTTTCCCGAGGTCGGCGCCGAACGTCAGGATATTCGCCAGTATCCCGGTGGCTCGCTGG CCGCCAACATCGTCGGCAGTATCGACTGGGAGGGTTACGGCCTTCTTGGGCTTGAGGATTCACTGGACAGTGCGCTGGCC GGCAAGGATGGATCGCTGACCTACGATCGCGGCTCCGACGGTGCGGTCATCCCCGGCAGCTACCGGGACCGCCATGACGC GGTGAACGGGTCCACCGTTGAACTCACGCTGGACAACGACATTCAGTTCTACGTGCAGCAGCAGGTCCAGCAGGCCAAGG ACTTGTCCGAAGCGCGCAGTGTGTCCGCGGTTGTTCTTGATTCCAAGACCGGTGAGGTCTTGGCGATGGCCAATGACAAT ACCTTTGACCCGTCGCAGAACCTGGGTAAGCAGGGCAACCGCGAGATGGGAAACCTCTCGGTCTCCTCGCCGTTCGAGCC GGGATCGGTCAACAAGGTCATCACCGCGTCGGCGGTGATCGAGAATGATTTGTCCAATCCCGATGAGGTGCTGCAGGTTC CGGGTTCCATCAACATGGGCGGGGTCACGGTCCGCGATGCGTGGCCGCACGGGACGGTGCCCTTCACCACCACGGGTGTT TTCGGGAAGTCGTCCAACGTGGGCACGCTCATGCTCGCCCAGCGGGTCGGGCCGGAGCGATTCATGGACCTGGTGGACAA GTTCGGCCTGGGACAGCGCACGGGTGTCGGCCTGCCCGGGGAGAGCGCCGGTATTGTGCCACCGATCGAGCAATGGTCGG GCAGCACGTTCTCGAATCTGCCGATCGGTCAGGGCTTGTCGATGACACTGCTGCAGATGGCCGGCATGTACCAGGCCATC GCCAACGACGGGGTGCGGATCCCGCCGCGCATCGTCAAGAGCATCACGGCGCCGGATGGGTCCCGTAAGGAGGAGCCACG CCCGGAACCCGTCCAGGTGGTCAACGCCGGAACCGCGCGTACCGTCCGGAACATGCTGCGCGCGGTGCTGCAGCCGGATG CGCGCCAGATTCAGAACGGCACCGGCGCGTCCGGCGCGGTCGACGGTTATCAGCTCAGCGGCAAAACCGGCACCGCCCAG CAGATCAATCCGGCCTGTGGGTGCTACTTCGATGACGTGTACTGGATCACATTCGCGGGCATCGCCACCACCGACGATCC CCGATACGTCATCGGCATCGAGATGAACGCGCCGAAACGAGGCTCGGATGGTAGTCCGCACATGACAGCCGCGCCGTTGT TCCACAACATCGCGTCCTGGCTGATGCGGCGCGAAAACGTGCCACTATCACCTGATCCCGGACCGCCACTGATCCTGCAG GCGACCTGA
Upstream 100 bases:
>100_bases CCCCCGTGGCCGACGCGCCGCAAGCATCAAATATCACGAATTCTCCAGTAACCGGGGAACAATTCAATCCCGTGGCAACA ACGAGTCCCCTCCCGGCGGC
Downstream 100 bases:
>100_bases GCCCGTCCTCGTCTGATCGGCGGCAGCCTGCCCGCCCGGTAATGTCGTTTGACGCCCGAGGACGAGCAGCCGGCGCGAAT ACCGTCGAGCCAGGGCATGG
Product: penicillin-binding membrane protein PbpB
Products: NA
Alternate protein names: PBP-2 [H]
Number of amino acids: Translated: 642; Mature: 642
Protein sequence:
>642_residues MNRQDRSRPVGARRTRRPAAAVSRTAGFAFRHRTGNIIIFLTLAIAAIQLFTLQGPRAAGLRAEASGQLKVTETEKALRG TIVDRAGNKLAFTIEARALTFQPKKIREQLNKAWEKSQEILKDPGKSDADKAAAAKIRSVEPERRLQDIANGVSAKLGNK PDAKSLLKKIRSDDTFAYLARSVDPGIAAQITKEFPEVGAERQDIRQYPGGSLAANIVGSIDWEGYGLLGLEDSLDSALA GKDGSLTYDRGSDGAVIPGSYRDRHDAVNGSTVELTLDNDIQFYVQQQVQQAKDLSEARSVSAVVLDSKTGEVLAMANDN TFDPSQNLGKQGNREMGNLSVSSPFEPGSVNKVITASAVIENDLSNPDEVLQVPGSINMGGVTVRDAWPHGTVPFTTTGV FGKSSNVGTLMLAQRVGPERFMDLVDKFGLGQRTGVGLPGESAGIVPPIEQWSGSTFSNLPIGQGLSMTLLQMAGMYQAI ANDGVRIPPRIVKSITAPDGSRKEEPRPEPVQVVNAGTARTVRNMLRAVLQPDARQIQNGTGASGAVDGYQLSGKTGTAQ QINPACGCYFDDVYWITFAGIATTDDPRYVIGIEMNAPKRGSDGSPHMTAAPLFHNIASWLMRRENVPLSPDPGPPLILQ AT
Sequences:
>Translated_642_residues MNRQDRSRPVGARRTRRPAAAVSRTAGFAFRHRTGNIIIFLTLAIAAIQLFTLQGPRAAGLRAEASGQLKVTETEKALRG TIVDRAGNKLAFTIEARALTFQPKKIREQLNKAWEKSQEILKDPGKSDADKAAAAKIRSVEPERRLQDIANGVSAKLGNK PDAKSLLKKIRSDDTFAYLARSVDPGIAAQITKEFPEVGAERQDIRQYPGGSLAANIVGSIDWEGYGLLGLEDSLDSALA GKDGSLTYDRGSDGAVIPGSYRDRHDAVNGSTVELTLDNDIQFYVQQQVQQAKDLSEARSVSAVVLDSKTGEVLAMANDN TFDPSQNLGKQGNREMGNLSVSSPFEPGSVNKVITASAVIENDLSNPDEVLQVPGSINMGGVTVRDAWPHGTVPFTTTGV FGKSSNVGTLMLAQRVGPERFMDLVDKFGLGQRTGVGLPGESAGIVPPIEQWSGSTFSNLPIGQGLSMTLLQMAGMYQAI ANDGVRIPPRIVKSITAPDGSRKEEPRPEPVQVVNAGTARTVRNMLRAVLQPDARQIQNGTGASGAVDGYQLSGKTGTAQ QINPACGCYFDDVYWITFAGIATTDDPRYVIGIEMNAPKRGSDGSPHMTAAPLFHNIASWLMRRENVPLSPDPGPPLILQ AT >Mature_642_residues MNRQDRSRPVGARRTRRPAAAVSRTAGFAFRHRTGNIIIFLTLAIAAIQLFTLQGPRAAGLRAEASGQLKVTETEKALRG TIVDRAGNKLAFTIEARALTFQPKKIREQLNKAWEKSQEILKDPGKSDADKAAAAKIRSVEPERRLQDIANGVSAKLGNK PDAKSLLKKIRSDDTFAYLARSVDPGIAAQITKEFPEVGAERQDIRQYPGGSLAANIVGSIDWEGYGLLGLEDSLDSALA GKDGSLTYDRGSDGAVIPGSYRDRHDAVNGSTVELTLDNDIQFYVQQQVQQAKDLSEARSVSAVVLDSKTGEVLAMANDN TFDPSQNLGKQGNREMGNLSVSSPFEPGSVNKVITASAVIENDLSNPDEVLQVPGSINMGGVTVRDAWPHGTVPFTTTGV FGKSSNVGTLMLAQRVGPERFMDLVDKFGLGQRTGVGLPGESAGIVPPIEQWSGSTFSNLPIGQGLSMTLLQMAGMYQAI ANDGVRIPPRIVKSITAPDGSRKEEPRPEPVQVVNAGTARTVRNMLRAVLQPDARQIQNGTGASGAVDGYQLSGKTGTAQ QINPACGCYFDDVYWITFAGIATTDDPRYVIGIEMNAPKRGSDGSPHMTAAPLFHNIASWLMRRENVPLSPDPGPPLILQ AT
Specific function: Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=561, Percent_Identity=29.4117647058824, Blast_Score=199, Evalue=7e-52, Organism=Escherichia coli, GI1786854, Length=417, Percent_Identity=24.220623501199, Blast_Score=78, Evalue=2e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: NA
Molecular weight: Translated: 68780; Mature: 68780
Theoretical pI: Translated: 8.88; Mature: 8.88
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRQDRSRPVGARRTRRPAAAVSRTAGFAFRHRTGNIIIFLTLAIAAIQLFTLQGPRAAG CCCCCCCCCCCCHHCCCCHHHHHHHHCEEEEECCCCEEEEHHHHHHHHHHHEECCCCCCC LRAEASGQLKVTETEKALRGTIVDRAGNKLAFTIEARALTFQPKKIREQLNKAWEKSQEI CCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHH LKDPGKSDADKAAAAKIRSVEPERRLQDIANGVSAKLGNKPDAKSLLKKIRSDDTFAYLA HHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHH RSVDPGIAAQITKEFPEVGAERQDIRQYPGGSLAANIVGSIDWEGYGLLGLEDSLDSALA HHCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHCCCCCCCEEEEECCHHHHHHHC GKDGSLTYDRGSDGAVIPGSYRDRHDAVNGSTVELTLDNDIQFYVQQQVQQAKDLSEARS CCCCCEEECCCCCCCCCCCCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHC VSAVVLDSKTGEVLAMANDNTFDPSQNLGKQGNREMGNLSVSSPFEPGSVNKVITASAVI EEEEEEECCCCCEEEEECCCCCCCHHHHCCCCCCCCCCEECCCCCCCCCCCCEEEHHHHH ENDLSNPDEVLQVPGSINMGGVTVRDAWPHGTVPFTTTGVFGKSSNVGTLMLAQRVGPER HHCCCCHHHHEECCCCCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCEEEHHHHCCHHH FMDLVDKFGLGQRTGVGLPGESAGIVPPIEQWSGSTFSNLPIGQGLSMTLLQMAGMYQAI HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH ANDGVRIPPRIVKSITAPDGSRKEEPRPEPVQVVNAGTARTVRNMLRAVLQPDARQIQNG HCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHCCC TGASGAVDGYQLSGKTGTAQQINPACGCYFDDVYWITFAGIATTDDPRYVIGIEMNAPKR CCCCCCCCCEEECCCCCCHHHCCCCCCCEECCEEEEEEECEEECCCCCEEEEEEECCCCC GSDGSPHMTAAPLFHNIASWLMRRENVPLSPDPGPPLILQAT CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC >Mature Secondary Structure MNRQDRSRPVGARRTRRPAAAVSRTAGFAFRHRTGNIIIFLTLAIAAIQLFTLQGPRAAG CCCCCCCCCCCCHHCCCCHHHHHHHHCEEEEECCCCEEEEHHHHHHHHHHHEECCCCCCC LRAEASGQLKVTETEKALRGTIVDRAGNKLAFTIEARALTFQPKKIREQLNKAWEKSQEI CCCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHH LKDPGKSDADKAAAAKIRSVEPERRLQDIANGVSAKLGNKPDAKSLLKKIRSDDTFAYLA HHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHH RSVDPGIAAQITKEFPEVGAERQDIRQYPGGSLAANIVGSIDWEGYGLLGLEDSLDSALA HHCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHCCCCCCCEEEEECCHHHHHHHC GKDGSLTYDRGSDGAVIPGSYRDRHDAVNGSTVELTLDNDIQFYVQQQVQQAKDLSEARS CCCCCEEECCCCCCCCCCCCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHC VSAVVLDSKTGEVLAMANDNTFDPSQNLGKQGNREMGNLSVSSPFEPGSVNKVITASAVI EEEEEEECCCCCEEEEECCCCCCCHHHHCCCCCCCCCCEECCCCCCCCCCCCEEEHHHHH ENDLSNPDEVLQVPGSINMGGVTVRDAWPHGTVPFTTTGVFGKSSNVGTLMLAQRVGPER HHCCCCHHHHEECCCCCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCEEEHHHHCCHHH FMDLVDKFGLGQRTGVGLPGESAGIVPPIEQWSGSTFSNLPIGQGLSMTLLQMAGMYQAI HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH ANDGVRIPPRIVKSITAPDGSRKEEPRPEPVQVVNAGTARTVRNMLRAVLQPDARQIQNG HCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHCCC TGASGAVDGYQLSGKTGTAQQINPACGCYFDDVYWITFAGIATTDDPRYVIGIEMNAPKR CCCCCCCCCEEECCCCCCHHHCCCCCCCEECCEEEEEEECEEECCCCCEEEEEEECCCCC GSDGSPHMTAAPLFHNIASWLMRRENVPLSPDPGPPLILQAT CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 3126399 [H]