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The map label for this gene is glnA [H]

Identifier: 169629008

GI number: 169629008

Start: 1920623

End: 1921963

Strand: Direct

Name: glnA [H]

Synonym: MAB_1920

Alternate gene names: 169629008

Gene position: 1920623-1921963 (Clockwise)

Preceding gene: 169629007

Following gene: 169629009

Centisome position: 37.9

GC content: 64.13

Gene sequence:

>1341_bases
ATGGATCGTCAGAAGGAATTCGTGCTGCGCACGCTGGAAGAACGCGATATCCGTTTCGTCCGGCTGTGGTTCACCGATGT
GCTCGGCTACCTCAAGAGCGTCTCCATTGCGCCCGCTGAGCTGGAGGGCGCTTTCGAGGAGGGCATCGGTTTCGATGGCT
CGTCCATCGAAGGCTTCGCCCGTGTCTCCGAATCGGACACCGTCGCCCACCCCGATCCGTCGACCTTCCAGGTGCTGCCC
TGGACCACGAGCGCGGGCAAGCACCACTCGGCGCGCATGTTCTGCGACATCAAACTGCCCGACGGCTCGCCGTCGTGGTC
GGACCCTCGGCACGTGCTGCGCCGTCAGCTGGCCAAGGCGAGCGATTTGGGCTTTTCCTGCTACGTACACCCGGAGATCG
AGTTCTTCCTGCTGAAGAACCTGCCCGACGACGGGACGGCACCCATCCCCGCCGACGACGCCGGATACTTCGACCAGGCA
GTGCACGAGGCCGCGCCCAACTTCCGCCGGCATGCGATCGACGCGCTCGAATCCATGGGCATCTCGGTGGAATTCAGCCA
CCACGAGGGTGCGCCCGGCCAGCAGGAGATCGATTTACGGTACGCCGACGCCCTTTCCATGGCGGACAACGTGATGACAT
TCCGGAACGTCGTCAAGGAAGTGGCGATCATCGACGGCGTGCATGCCACGTTCATGCCCAAGCCGTTCAGTGATCACCCC
GGCAGTGCCATGCACACCCATATGAGCCTGTTCGAGGGCGATACCAACGCCTTCCACAATCCCGATGACCCGCTTCAGCT
TTCGGATGTCGGCAAGTCGTTCATCGCCGGCATCCTGGAGCACGCCAACGAGATCAGCGCCGTCACCAATCAGTGGGTGA
ATTCCTACAAGCGCCTGGTGCAGGGCGGTGAGGCGCCGACGGCGGCGTCCTGGGGTGCGGCCAACCGTTCGGCGCTGGTG
CGGGTTCCGATGTACACGCCCAACAAGTCGTCGTCACGTCGCATCGAGGTACGCAGCCCGGACTCCGCGTGCAACCCGTA
TCTGACGTATGCGGTGCTGCTGGCCGCCGGTCTGCGGGGTGTGGAGCAGGGCTACACCCTGGGCCCGGAAGCCGAGGACG
ACGTCTGGGGCCTGACCCGTGCGGAGCGCCAGGCCATGGGCTACAAGGAGCTGCCCAGCACGCTGGAGAACGCCCTCATC
GCGATGGAGGGCTCCGAGCTGGTCGCAGAAGCCTTGGGAGAGCATGTCTTTGACTTCTTCCTGCGCAACAAGCGGGCCGA
GTGGGCGCGCTACCGCAGCAATGTGACGCCGTTCGAACTGCGTGCCTACTTGGGTCTGTGA

Upstream 100 bases:

>100_bases
AACGGTGAGGCATGTGTCGATGACGTGGTGACGCGCTACTTCGTCGACGGCACCGTGCCTCCTAAAGACGTGCGCTGCTG
ACCTGCGGCATACTCTCCCC

Downstream 100 bases:

>100_bases
CGCGATCTTCTGAGCGTTCGAAGGTCCCTGGTGTCGGGCGGCTGGGGCTTGTCGATCCGCGGGCCGCGGCACTGCTCGAA
GAGCTGGGCTGGACCACCGA

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase 2 [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVSIAPAELEGAFEEGIGFDGSSIEGFARVSESDTVAHPDPSTFQVLP
WTTSAGKHHSARMFCDIKLPDGSPSWSDPRHVLRRQLAKASDLGFSCYVHPEIEFFLLKNLPDDGTAPIPADDAGYFDQA
VHEAAPNFRRHAIDALESMGISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRNVVKEVAIIDGVHATFMPKPFSDHP
GSAMHTHMSLFEGDTNAFHNPDDPLQLSDVGKSFIAGILEHANEISAVTNQWVNSYKRLVQGGEAPTAASWGAANRSALV
RVPMYTPNKSSSRRIEVRSPDSACNPYLTYAVLLAAGLRGVEQGYTLGPEAEDDVWGLTRAERQAMGYKELPSTLENALI
AMEGSELVAEALGEHVFDFFLRNKRAEWARYRSNVTPFELRAYLGL

Sequences:

>Translated_446_residues
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVSIAPAELEGAFEEGIGFDGSSIEGFARVSESDTVAHPDPSTFQVLP
WTTSAGKHHSARMFCDIKLPDGSPSWSDPRHVLRRQLAKASDLGFSCYVHPEIEFFLLKNLPDDGTAPIPADDAGYFDQA
VHEAAPNFRRHAIDALESMGISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRNVVKEVAIIDGVHATFMPKPFSDHP
GSAMHTHMSLFEGDTNAFHNPDDPLQLSDVGKSFIAGILEHANEISAVTNQWVNSYKRLVQGGEAPTAASWGAANRSALV
RVPMYTPNKSSSRRIEVRSPDSACNPYLTYAVLLAAGLRGVEQGYTLGPEAEDDVWGLTRAERQAMGYKELPSTLENALI
AMEGSELVAEALGEHVFDFFLRNKRAEWARYRSNVTPFELRAYLGL
>Mature_446_residues
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVSIAPAELEGAFEEGIGFDGSSIEGFARVSESDTVAHPDPSTFQVLP
WTTSAGKHHSARMFCDIKLPDGSPSWSDPRHVLRRQLAKASDLGFSCYVHPEIEFFLLKNLPDDGTAPIPADDAGYFDQA
VHEAAPNFRRHAIDALESMGISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRNVVKEVAIIDGVHATFMPKPFSDHP
GSAMHTHMSLFEGDTNAFHNPDDPLQLSDVGKSFIAGILEHANEISAVTNQWVNSYKRLVQGGEAPTAASWGAANRSALV
RVPMYTPNKSSSRRIEVRSPDSACNPYLTYAVLLAAGLRGVEQGYTLGPEAEDDVWGLTRAERQAMGYKELPSTLENALI
AMEGSELVAEALGEHVFDFFLRNKRAEWARYRSNVTPFELRAYLGL

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=442, Percent_Identity=27.6018099547511, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1790301, Length=475, Percent_Identity=34.3157894736842, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI87081870, Length=388, Percent_Identity=28.8659793814433, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 49420; Mature: 49420

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVSIAPAELEGAFEEGIGFDGSSIEGFA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHH
RVSESDTVAHPDPSTFQVLPWTTSAGKHHSARMFCDIKLPDGSPSWSDPRHVLRRQLAKA
HCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHH
SDLGFSCYVHPEIEFFLLKNLPDDGTAPIPADDAGYFDQAVHEAAPNFRRHAIDALESMG
HCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCC
ISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRNVVKEVAIIDGVHATFMPKPFSDHP
CEEEECCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
GSAMHTHMSLFEGDTNAFHNPDDPLQLSDVGKSFIAGILEHANEISAVTNQWVNSYKRLV
CCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGGEAPTAASWGAANRSALVRVPMYTPNKSSSRRIEVRSPDSACNPYLTYAVLLAAGLRG
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
VEQGYTLGPEAEDDVWGLTRAERQAMGYKELPSTLENALIAMEGSELVAEALGEHVFDFF
HHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHH
LRNKRAEWARYRSNVTPFELRAYLGL
HHCCHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVSIAPAELEGAFEEGIGFDGSSIEGFA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHH
RVSESDTVAHPDPSTFQVLPWTTSAGKHHSARMFCDIKLPDGSPSWSDPRHVLRRQLAKA
HCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHH
SDLGFSCYVHPEIEFFLLKNLPDDGTAPIPADDAGYFDQAVHEAAPNFRRHAIDALESMG
HCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCC
ISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRNVVKEVAIIDGVHATFMPKPFSDHP
CEEEECCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
GSAMHTHMSLFEGDTNAFHNPDDPLQLSDVGKSFIAGILEHANEISAVTNQWVNSYKRLV
CCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGGEAPTAASWGAANRSALVRVPMYTPNKSSSRRIEVRSPDSACNPYLTYAVLLAAGLRG
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
VEQGYTLGPEAEDDVWGLTRAERQAMGYKELPSTLENALIAMEGSELVAEALGEHVFDFF
HHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHH
LRNKRAEWARYRSNVTPFELRAYLGL
HHCCHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA