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The map label for this gene is rnr [H]

Identifier: 169629001

GI number: 169629001

Start: 1909994

End: 1911514

Strand: Direct

Name: rnr [H]

Synonym: MAB_1913

Alternate gene names: 169629001

Gene position: 1909994-1911514 (Clockwise)

Preceding gene: 169628995

Following gene: 169629003

Centisome position: 37.69

GC content: 67.0

Gene sequence:

>1521_bases
ATGGATGGTCGCCGCCGCGTGGCCGCGGCTAGCCCGTGGCTGTGCGGAACAGGATCCGGCTTACAGGCCAACTCGTTCGC
CTCTTACCCTGAACCGGTGACGTTGAAGCGACTGGTTGCTCGCGACCTCAACTTCGACGGCATTCGTACCGAGTTCGGGT
TGCCCGCAGAATTCAGCCCCGAAGCCCAGCGCGATGCTGCCCAGGCAGTGGACCGCTATCGCGCAGCACGCGTCGATCGC
ACCGATCTGGAGCTGGTGACCATCGACCCGCCCGGATCCCGTGACCTGGACCAGGCCCTGCGCCTGGAACGCACCGCCGA
CGGCTACCTGCTGCACTACGCCATTGCTGACGTTGCGGCGCAGATCGAGCCCGGCAGCACACTGGATATCGAGGCACGTG
AACGCGGCGAGACGATCTACCTACCCGATGGTTCGGTACCGCTGCATCCGTTGGTGTTCTCCGAGGGCTCGGCGAGCTTG
TTGCCCCACGAGATCAGGCCCGCCGCCTTGTGGCGGATCGAGACCGACCACGATGCCAACCCGGTGGCGTGGACCGTGCA
GCGCGCCCTCGTGAAATCCGTGCGACAGCTGACTTACCGGGAGGCTCAGGACGCGGCCGCCGCGGGCAATCCGCATCCCG
CCGTGGCCGTACTCCCTGAATTTGGCCGCAAAAGACGAGATCTCGGGCTAGCCAGGGGCGCCATCGAGCTCAATCTGCCC
GAGCAGGATGTGGTGCGCGGCGCCGGCGGTGACTGGGAGCTCGTCATCGAGGCGCGCACCGAAACCGACGGCTGGAACGC
GCAGATATCGCTGCTCACCGGGATCTGCGCGGCACGGATCATGCTCGACGGCGGGATCGGCATGCTGCGTACGTTGCCGC
CGGCGGACGGCGATGTGCGCCGCTGGATGCGCCGCACCGCCGAGGCCCTCGGGGTTCCATGGACCAACGACACACCGATA
GGGGAGCAGCTCGCCGCGCTAGACCCCTGCGCCACAACCACATTGGCGATGATGACGCAGGCCACGACGCTGCTGCGGGG
TGCCTCGTATCTGGTTTTCGACGGTGTACGTCCCGACGAGCAGGCCGCTCAACACGCCGGTATCGCCGCCCCCTACGCGC
ATGTGACCGCACCCTTGCGCAGGCTGGGGGACCGGTTTGTCACCGAAATCTGCCTGGCACTGTCCGCCGGCACCCCGGTG
CCGCAATGGGCCCGCGAGGGCCTGGCCGACATTCGATCGTCCTTGCTGAAATCGAACACGTTGGCCAACAAGGTGGAGCA
GGCGTGCCTGGATCTCGCCGAGGCCCACATCCTGGCCCCGCAACAGGGGCAGACCTTCGACTCGGTGGTGCTGCGAGGCG
CCGAGAAGAAGCGGGCTGCGGAGGTTTTCGTGAGCGATCCGCCGATTCTTGCCCGGTGCGAGGGCAATCCGCCCGAAGGT
CAGCGCGCCAAACTCACCCTGCGTGAAGCCGACCCCGTCACCAGGACCGTGCTATTCGGGTTCCCGGCGGACGGCCGCTG
A

Upstream 100 bases:

>100_bases
GGCCAAAAGGCTGTGCGTGCACAGCTGCGGAAGTGTTCGAGGGCTGCTCGCCCGAGCTTCCGGGTAGGCCGCTCGAGGTA
CCCGGCGACGGTGTACCCAG

Downstream 100 bases:

>100_bases
TCACTTCTTGTGACGCACCGCCTTGCGGAGCGCCTTCAGTGTCGCCTCCACCTGGTGGCGCGCCGTCTCCGCCGCATCGT
GCTCACGCTGGTACAGCACT

Product: hypothetical protein

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDGRRRVAAASPWLCGTGSGLQANSFASYPEPVTLKRLVARDLNFDGIRTEFGLPAEFSPEAQRDAAQAVDRYRAARVDR
TDLELVTIDPPGSRDLDQALRLERTADGYLLHYAIADVAAQIEPGSTLDIEARERGETIYLPDGSVPLHPLVFSEGSASL
LPHEIRPAALWRIETDHDANPVAWTVQRALVKSVRQLTYREAQDAAAAGNPHPAVAVLPEFGRKRRDLGLARGAIELNLP
EQDVVRGAGGDWELVIEARTETDGWNAQISLLTGICAARIMLDGGIGMLRTLPPADGDVRRWMRRTAEALGVPWTNDTPI
GEQLAALDPCATTTLAMMTQATTLLRGASYLVFDGVRPDEQAAQHAGIAAPYAHVTAPLRRLGDRFVTEICLALSAGTPV
PQWAREGLADIRSSLLKSNTLANKVEQACLDLAEAHILAPQQGQTFDSVVLRGAEKKRAAEVFVSDPPILARCEGNPPEG
QRAKLTLREADPVTRTVLFGFPADGR

Sequences:

>Translated_506_residues
MDGRRRVAAASPWLCGTGSGLQANSFASYPEPVTLKRLVARDLNFDGIRTEFGLPAEFSPEAQRDAAQAVDRYRAARVDR
TDLELVTIDPPGSRDLDQALRLERTADGYLLHYAIADVAAQIEPGSTLDIEARERGETIYLPDGSVPLHPLVFSEGSASL
LPHEIRPAALWRIETDHDANPVAWTVQRALVKSVRQLTYREAQDAAAAGNPHPAVAVLPEFGRKRRDLGLARGAIELNLP
EQDVVRGAGGDWELVIEARTETDGWNAQISLLTGICAARIMLDGGIGMLRTLPPADGDVRRWMRRTAEALGVPWTNDTPI
GEQLAALDPCATTTLAMMTQATTLLRGASYLVFDGVRPDEQAAQHAGIAAPYAHVTAPLRRLGDRFVTEICLALSAGTPV
PQWAREGLADIRSSLLKSNTLANKVEQACLDLAEAHILAPQQGQTFDSVVLRGAEKKRAAEVFVSDPPILARCEGNPPEG
QRAKLTLREADPVTRTVLFGFPADGR
>Mature_506_residues
MDGRRRVAAASPWLCGTGSGLQANSFASYPEPVTLKRLVARDLNFDGIRTEFGLPAEFSPEAQRDAAQAVDRYRAARVDR
TDLELVTIDPPGSRDLDQALRLERTADGYLLHYAIADVAAQIEPGSTLDIEARERGETIYLPDGSVPLHPLVFSEGSASL
LPHEIRPAALWRIETDHDANPVAWTVQRALVKSVRQLTYREAQDAAAAGNPHPAVAVLPEFGRKRRDLGLARGAIELNLP
EQDVVRGAGGDWELVIEARTETDGWNAQISLLTGICAARIMLDGGIGMLRTLPPADGDVRRWMRRTAEALGVPWTNDTPI
GEQLAALDPCATTTLAMMTQATTLLRGASYLVFDGVRPDEQAAQHAGIAAPYAHVTAPLRRLGDRFVTEICLALSAGTPV
PQWAREGLADIRSSLLKSNTLANKVEQACLDLAEAHILAPQQGQTFDSVVLRGAEKKRAAEVFVSDPPILARCEGNPPEG
QRAKLTLREADPVTRTVLFGFPADGR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=373, Percent_Identity=26.5415549597855, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI190014623, Length=373, Percent_Identity=26.5415549597855, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI87082383, Length=325, Percent_Identity=29.2307692307692, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787542, Length=335, Percent_Identity=25.0746268656716, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI212645896, Length=389, Percent_Identity=27.2493573264781, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324552, Length=329, Percent_Identity=27.0516717325228, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24649634, Length=398, Percent_Identity=28.643216080402, Blast_Score=104, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 54804; Mature: 54804

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGRRRVAAASPWLCGTGSGLQANSFASYPEPVTLKRLVARDLNFDGIRTEFGLPAEFSP
CCCCCCEECCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EAQRDAAQAVDRYRAARVDRTDLELVTIDPPGSRDLDQALRLERTADGYLLHYAIADVAA
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHH
QIEPGSTLDIEARERGETIYLPDGSVPLHPLVFSEGSASLLPHEIRPAALWRIETDHDAN
HCCCCCEEEEEHHCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCC
PVAWTVQRALVKSVRQLTYREAQDAAAAGNPHPAVAVLPEFGRKRRDLGLARGAIELNLP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHCCHHHHHHHHCCEEEECCC
EQDVVRGAGGDWELVIEARTETDGWNAQISLLTGICAARIMLDGGIGMLRTLPPADGDVR
HHHHHHCCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHH
RWMRRTAEALGVPWTNDTPIGEQLAALDPCATTTLAMMTQATTLLRGASYLVFDGVRPDE
HHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHH
QAAQHAGIAAPYAHVTAPLRRLGDRFVTEICLALSAGTPVPQWAREGLADIRSSLLKSNT
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LANKVEQACLDLAEAHILAPQQGQTFDSVVLRGAEKKRAAEVFVSDPPILARCEGNPPEG
HHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCHHHHHEEEECCCCEEEEECCCCCCC
QRAKLTLREADPVTRTVLFGFPADGR
CCEEEEEECCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MDGRRRVAAASPWLCGTGSGLQANSFASYPEPVTLKRLVARDLNFDGIRTEFGLPAEFSP
CCCCCCEECCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
EAQRDAAQAVDRYRAARVDRTDLELVTIDPPGSRDLDQALRLERTADGYLLHYAIADVAA
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHH
QIEPGSTLDIEARERGETIYLPDGSVPLHPLVFSEGSASLLPHEIRPAALWRIETDHDAN
HCCCCCEEEEEHHCCCCEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCC
PVAWTVQRALVKSVRQLTYREAQDAAAAGNPHPAVAVLPEFGRKRRDLGLARGAIELNLP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHCCHHHHHHHHCCEEEECCC
EQDVVRGAGGDWELVIEARTETDGWNAQISLLTGICAARIMLDGGIGMLRTLPPADGDVR
HHHHHHCCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHH
RWMRRTAEALGVPWTNDTPIGEQLAALDPCATTTLAMMTQATTLLRGASYLVFDGVRPDE
HHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCHH
QAAQHAGIAAPYAHVTAPLRRLGDRFVTEICLALSAGTPVPQWAREGLADIRSSLLKSNT
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LANKVEQACLDLAEAHILAPQQGQTFDSVVLRGAEKKRAAEVFVSDPPILARCEGNPPEG
HHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCHHHHHEEEECCCCEEEEECCCCCCC
QRAKLTLREADPVTRTVLFGFPADGR
CCEEEEEECCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]