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The map label for this gene is fur [H]

Identifier: 169628768

GI number: 169628768

Start: 1705102

End: 1705560

Strand: Reverse

Name: fur [H]

Synonym: MAB_1678c

Alternate gene names: 169628768

Gene position: 1705560-1705102 (Counterclockwise)

Preceding gene: 169628769

Following gene: 169628764

Centisome position: 33.66

GC content: 66.45

Gene sequence:

>459_bases
ATGACTCCCGCGCAGGCCGGGGGGTCGCCAAGCGTGCACGAGGACAGGCCGGCATTGCGCGGAACGGTGCGTTCCACCCG
TCAGCGCGCGGCCATCACCGCCCTGCTCAAGCGCACCGATGAATTCAAGTCGGCGCAGGATCTACACGACGAGCTCAAGC
GCGACGGCGAGGGCATCGGCCTGACCACCGTCTACCGCACCCTGCAGTCGATGTCGACATCGGGTGAGGTGGATGTGCTG
CGCAACGACACCGGCGAGTCGGTGTACCGGCGCTGCTCGGACGGCCATCACCATCACTTGGTCTGCCAGAGTTGCGGTTT
CGCGGTCGAGGTGCAGGCAGGCGCGGTCGAGAAGTGGGCGACCGACATCGCCGAAGAGCACGGTTTCACCGAGGTACACC
ACACCGTCGAGGTCTTCGGTTTCTGCAGCCGCTGCACCGCCGAGCGCCGAAGCTCCTAG

Upstream 100 bases:

>100_bases
TCTCGGGCGAACGGCAGGGCCGTGAGGTGATGTACCGCCTCGTCGACGACCACCTCTCCCACATCGTGGTCGACGCGGTT
GCCCATACCGAGGAACAAAG

Downstream 100 bases:

>100_bases
TTGCCCAATGCCTTTCGCGCGTCAGCGCCGGTGGCGAACACCATCATGAGCAGTGTCACCAGGGCGTCGTCGTCATCGAT
CCCGGTGGCCGGAAAGTTGT

Product: putative ferric uptake regulator FurB

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MTPAQAGGSPSVHEDRPALRGTVRSTRQRAAITALLKRTDEFKSAQDLHDELKRDGEGIGLTTVYRTLQSMSTSGEVDVL
RNDTGESVYRRCSDGHHHHLVCQSCGFAVEVQAGAVEKWATDIAEEHGFTEVHHTVEVFGFCSRCTAERRSS

Sequences:

>Translated_152_residues
MTPAQAGGSPSVHEDRPALRGTVRSTRQRAAITALLKRTDEFKSAQDLHDELKRDGEGIGLTTVYRTLQSMSTSGEVDVL
RNDTGESVYRRCSDGHHHHLVCQSCGFAVEVQAGAVEKWATDIAEEHGFTEVHHTVEVFGFCSRCTAERRSS
>Mature_151_residues
TPAQAGGSPSVHEDRPALRGTVRSTRQRAAITALLKRTDEFKSAQDLHDELKRDGEGIGLTTVYRTLQSMSTSGEVDVLR
NDTGESVYRRCSDGHHHHLVCQSCGFAVEVQAGAVEKWATDIAEEHGFTEVHHTVEVFGFCSRCTAERRSS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=125, Percent_Identity=32.8, Blast_Score=73, Evalue=6e-15,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16727; Mature: 16595

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAQAGGSPSVHEDRPALRGTVRSTRQRAAITALLKRTDEFKSAQDLHDELKRDGEGIG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LTTVYRTLQSMSTSGEVDVLRNDTGESVYRRCSDGHHHHLVCQSCGFAVEVQAGAVEKWA
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHHCCCEEEECCCHHHHHH
TDIAEEHGFTEVHHTVEVFGFCSRCTAERRSS
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPAQAGGSPSVHEDRPALRGTVRSTRQRAAITALLKRTDEFKSAQDLHDELKRDGEGIG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LTTVYRTLQSMSTSGEVDVLRNDTGESVYRRCSDGHHHHLVCQSCGFAVEVQAGAVEKWA
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCHHHHHHHCCCEEEECCCHHHHHH
TDIAEEHGFTEVHHTVEVFGFCSRCTAERRSS
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8996110 [H]