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The map label for this gene is clpX [H]

Identifier: 169628673

GI number: 169628673

Start: 1612822

End: 1614102

Strand: Direct

Name: clpX [H]

Synonym: MAB_1583

Alternate gene names: 169628673

Gene position: 1612822-1614102 (Clockwise)

Preceding gene: 169628672

Following gene: 169628674

Centisome position: 31.83

GC content: 62.61

Gene sequence:

>1281_bases
ATGGCACGTATCGGAGACGGCGGCGACCTGCTGAAATGCTCGTTCTGCGGAAAGAGCCAGAAGCAGGTCAAGAAGCTCAT
CGCCGGCCCCGGCGTGTACATCTGCGATGAATGCATCGACCTCTGCAACGAGATCATCGAAGAGGAGTTGGCCGACGCCG
ACGACGTCAAGCTTGATGAACTGCCCAAGCCCGCAGAGATCCGCGACTTCCTGGAGAACTACGTCATCGGCCAGGACACC
GCGAAGAAGACGCTGGCTGTCGCCGTCTACAACCACTACAAGCGCATCCAGGCCGGGGACAAGGCTCGCGACGCCCGCGG
CGAGACCGTTGAACTGGCCAAGTCCAATATCTTGATGCTCGGCCCGACCGGCTGCGGCAAGACCTACCTGGCGCAGACGC
TCGCCAAGATGCTCAACGTGCCGTTCGCGATCGCAGATGCCACCGCGCTGACCGAGGCCGGATATGTCGGCGAGGATGTG
GAGAACATTCTCCTCAAGCTGATTCAGGCCGCCGACTACGACGTGAAGCGTGCCGAGACCGGCATCATCTACATCGACGA
GGTCGACAAGATCGCCCGCAAGAGCGAGAACCCGTCCATCACCCGCGATGTCTCCGGTGAGGGCGTACAGCAGGCGTTGC
TGAAGATCCTGGAAGGCACGCAGGCCTCGGTGCCCCCGCAGGGTGGCCGCAAGCACCCGCATCAGGAGTTCATCCAGATC
GACACCACCAACGTGCTCTTCATCGTGGCGGGCGCATTCGCAGGCCTGGAGAAGATCGTTTCGGATCGTGTCGGCAAGCG
CGGCCTGGGCTTCGGCGCCGAGGTCAAGTCCAAGGCCGACATCGACACCACCGACCACTTCGCAGAGGTCATGCCCGAGG
ATCTGATCAAGTTCGGGCTCATCCCCGAGTTCATCGGCCGTCTGCCGATCGTCGCCTCGGTGACCAACCTTGATCGCGAG
TCGCTCATCAAGATTCTGTCCGAGCCGAAGAACGCGTTGGTGAAGCAGTACACCCGCCTCTTCGAGATGGACGGGGTCGA
GCTGGAATTCAGCCAGGACGCGCTGGAGGCCATCGCCGATCAGGCCATCCACCGTGGCACCGGTGCCCGCGGTCTGCGCG
CCATCATGGAGGAAGTCTTGCAGCCGGTGATGTACGACATCCCGAGCCGCGACGATGTCGCCAAGGTCGTTGTGACCGGA
GAGACCGTGATCGACAACGTGCTGCCGACGATCGTTCCGCGTAAGCCCTCGCGCACCGAGCGGCGCGACAAGTCCGCGTA
G

Upstream 100 bases:

>100_bases
CGGTGCGGCCGATATTGCGGGTAGCGTCGGGACCAACAGGTCAGAGGACGTGTTGACACCACGATCCACCACCGCGTGAC
AGGAAGTAGGACTGGCCACC

Downstream 100 bases:

>100_bases
GTCCTCGTGCAGAGCGCCATGGAGCTGGCGCGGGCCGAGCGTATCGACCTCGCCGACTTTCTGGCCGGATTGACCGCCGA
GCAGTGGGATGCGCCCTCGT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIRDFLENYVIGQDT
AKKTLAVAVYNHYKRIQAGDKARDARGETVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDV
ENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
DTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVKSKADIDTTDHFAEVMPEDLIKFGLIPEFIGRLPIVASVTNLDRE
SLIKILSEPKNALVKQYTRLFEMDGVELEFSQDALEAIADQAIHRGTGARGLRAIMEEVLQPVMYDIPSRDDVAKVVVTG
ETVIDNVLPTIVPRKPSRTERRDKSA

Sequences:

>Translated_426_residues
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIRDFLENYVIGQDT
AKKTLAVAVYNHYKRIQAGDKARDARGETVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDV
ENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
DTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVKSKADIDTTDHFAEVMPEDLIKFGLIPEFIGRLPIVASVTNLDRE
SLIKILSEPKNALVKQYTRLFEMDGVELEFSQDALEAIADQAIHRGTGARGLRAIMEEVLQPVMYDIPSRDDVAKVVVTG
ETVIDNVLPTIVPRKPSRTERRDKSA
>Mature_425_residues
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIRDFLENYVIGQDTA
KKTLAVAVYNHYKRIQAGDKARDARGETVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVE
NILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQID
TTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVKSKADIDTTDHFAEVMPEDLIKFGLIPEFIGRLPIVASVTNLDRES
LIKILSEPKNALVKQYTRLFEMDGVELEFSQDALEAIADQAIHRGTGARGLRAIMEEVLQPVMYDIPSRDDVAKVVVTGE
TVIDNVLPTIVPRKPSRTERRDKSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=351, Percent_Identity=47.5783475783476, Blast_Score=299, Evalue=4e-81,
Organism=Escherichia coli, GI1786642, Length=413, Percent_Identity=63.680387409201, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=108, Percent_Identity=44.4444444444444, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=45.016077170418, Blast_Score=268, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=45.016077170418, Blast_Score=267, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI71988663, Length=413, Percent_Identity=37.2881355932203, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=39.0438247011952, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6319704, Length=428, Percent_Identity=39.018691588785, Blast_Score=273, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24648291, Length=330, Percent_Identity=45.1515151515152, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24648289, Length=330, Percent_Identity=45.1515151515152, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46564; Mature: 46433

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDE
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHC
LPKPAEIRDFLENYVIGQDTAKKTLAVAVYNHYKRIQAGDKARDARGETVELAKSNILML
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEHHCCEEEE
GPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAET
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCC
GIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
CEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEE
DTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVKSKADIDTTDHFAEVMPEDLIKFGL
CCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
IPEFIGRLPIVASVTNLDRESLIKILSEPKNALVKQYTRLFEMDGVELEFSQDALEAIAD
HHHHHCCCCHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
QAIHRGTGARGLRAIMEEVLQPVMYDIPSRDDVAKVVVTGETVIDNVLPTIVPRKPSRTE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCHH
RRDKSA
HCCCCC
>Mature Secondary Structure 
ARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDE
CCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHC
LPKPAEIRDFLENYVIGQDTAKKTLAVAVYNHYKRIQAGDKARDARGETVELAKSNILML
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEHHCCEEEE
GPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAET
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCC
GIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQI
CEEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEEE
DTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVKSKADIDTTDHFAEVMPEDLIKFGL
CCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
IPEFIGRLPIVASVTNLDRESLIKILSEPKNALVKQYTRLFEMDGVELEFSQDALEAIAD
HHHHHCCCCHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
QAIHRGTGARGLRAIMEEVLQPVMYDIPSRDDVAKVVVTGETVIDNVLPTIVPRKPSRTE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHCCCCCCCHH
RRDKSA
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA