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The map label for this gene is fbpC [H]

Identifier: 169628669

GI number: 169628669

Start: 1608202

End: 1609197

Strand: Direct

Name: fbpC [H]

Synonym: MAB_1579

Alternate gene names: 169628669

Gene position: 1608202-1609197 (Clockwise)

Preceding gene: 169628666

Following gene: 169628670

Centisome position: 31.74

GC content: 62.75

Gene sequence:

>996_bases
ATGGAATTCCTGCAGAAGATGCGCGGCGCAACCGCGCGCCTGGCTGCTGTTGCCGCGGTCGCTGCGGCGATATTGCCCGG
TCTGATCGGCGTGACAGGCGGTTCGGCGATCGCGGGGGCCTTCTCACGCCCGGGATTGCCGGTCGAATACCTGCAGGTGC
CTTCGCCCGCCATGGGGCGCGACATCGTGGTCGAGTTTCAGCCCGGTGGTCCCCACGCGGTCTACCTACTGGATGGCCAG
CGTGCCCGCGAGGATTACAACGGCTGGGATATCGAGACGACCGCGTTCGAGGACTACTACCAGTCGGGTATCTCGGTCGT
CATGCCCGTCGGTGGGCAATCGAGCAATTACACCGATTGGTACAACCCGGCCAAAGGCAAAGACGGGGTATGGACGTACA
AGTGGGAAACCTTTCTGACCACAGAATTGCCGCAGTGGCTGGGTGTCAACAAGGGCATCTCGCCGGCGGCGAACGCCGTG
GTCGGACTGTCCATGGCGGGCCCGTCCGCCCTGACGCTGGCGATCTACCACCCGCAACAGTTCGTATACGCGGGTGCACT
GTCTGCGCCGCTTCATCCCTCCGACCAGAAATGGCAGATCCGGGTGGCTATGAGCGATGCCGGTGGCTTCAACGCGGACG
ACATGTGGGGCCCGGACAGCGATCCAGCGTGGGCTCGCAACGACCCGTTTCTGCACATCGATCAGCTCATCGCGAACAAC
ACTCGACTGTGGATCTATTGCGGCAGTGGTGATGCCACCGACCTCGACAAGGATCGCAACGGCCTCGAGGTCATCTCCGG
TGGCGTCATCGAGGGGCAGGTGATCGATTCGGACAAGAAGTTCGCCGAGGCCTATGGCTCGGCGGGTGGCGCCAACGCAC
ACTTCGAATTTCCCAAGGGAGGCATCCACAACTGGACATACTGGGGCAACCAACTACGTGCCATGAAGGCCGATCTGGTC
GGGTACCTGACCAAGCCGGGCACGGCCGCCGTATGA

Upstream 100 bases:

>100_bases
ACACTGTTTGCATGGACTCCACCAGCGAGCTAGCCTTCACAAACAGTGTTTCAAACACTGTTTGAATCGAGAATTGCCGG
ACAAGTGGAGGTTGAGAAAG

Downstream 100 bases:

>100_bases
GCCGAACTCACCGATGAGAGGAGTGGTCAATGGGCCGCGGGCGCCCCGATCGGGTTCTCCACCTGATCGGGCGTCGGCCC
CGGAGTGCTGCTGGAGCGGG

Product: antigen 85-B precursor

Products: NA

Alternate protein names: Antigen 85 complex C; 85C; Ag85C; Fibronectin-binding protein C; Mycolyl transferase 85C [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEFLQKMRGATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSRPGLPVEYLQVPSPAMGRDIVVEFQPGGPHAVYLLDGQ
RAREDYNGWDIETTAFEDYYQSGISVVMPVGGQSSNYTDWYNPAKGKDGVWTYKWETFLTTELPQWLGVNKGISPAANAV
VGLSMAGPSALTLAIYHPQQFVYAGALSAPLHPSDQKWQIRVAMSDAGGFNADDMWGPDSDPAWARNDPFLHIDQLIANN
TRLWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGSAGGANAHFEFPKGGIHNWTYWGNQLRAMKADLV
GYLTKPGTAAV

Sequences:

>Translated_331_residues
MEFLQKMRGATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSRPGLPVEYLQVPSPAMGRDIVVEFQPGGPHAVYLLDGQ
RAREDYNGWDIETTAFEDYYQSGISVVMPVGGQSSNYTDWYNPAKGKDGVWTYKWETFLTTELPQWLGVNKGISPAANAV
VGLSMAGPSALTLAIYHPQQFVYAGALSAPLHPSDQKWQIRVAMSDAGGFNADDMWGPDSDPAWARNDPFLHIDQLIANN
TRLWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGSAGGANAHFEFPKGGIHNWTYWGNQLRAMKADLV
GYLTKPGTAAV
>Mature_331_residues
MEFLQKMRGATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSRPGLPVEYLQVPSPAMGRDIVVEFQPGGPHAVYLLDGQ
RAREDYNGWDIETTAFEDYYQSGISVVMPVGGQSSNYTDWYNPAKGKDGVWTYKWETFLTTELPQWLGVNKGISPAANAV
VGLSMAGPSALTLAIYHPQQFVYAGALSAPLHPSDQKWQIRVAMSDAGGFNADDMWGPDSDPAWARNDPFLHIDQLIANN
TRLWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGSAGGANAHFEFPKGGIHNWTYWGNQLRAMKADLV
GYLTKPGTAAV

Specific function: Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintain

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial A85 antigen family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 35504; Mature: 35504

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLQKMRGATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSRPGLPVEYLQVPSPAMGR
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEECCCCCCCC
DIVVEFQPGGPHAVYLLDGQRAREDYNGWDIETTAFEDYYQSGISVVMPVGGQSSNYTDW
EEEEEEECCCCEEEEEECCHHHHCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCCC
YNPAKGKDGVWTYKWETFLTTELPQWLGVNKGISPAANAVVGLSMAGPSALTLAIYHPQQ
CCCCCCCCCEEEEEEEEEEEHHCHHHHCCCCCCCCHHHHEEEEEECCCCEEEEEEECCCC
FVYAGALSAPLHPSDQKWQIRVAMSDAGGFNADDMWGPDSDPAWARNDPFLHIDQLIANN
EEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHCC
TRLWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGSAGGANAHFEFPKG
CEEEEEECCCCCCCCCCCCCCCEEEECCEEEEEEECCHHHHHHHHCCCCCCCCEEECCCC
GIHNWTYWGNQLRAMKADLVGYLTKPGTAAV
CCCCCEEECCHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MEFLQKMRGATARLAAVAAVAAAILPGLIGVTGGSAIAGAFSRPGLPVEYLQVPSPAMGR
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEECCCCCCCC
DIVVEFQPGGPHAVYLLDGQRAREDYNGWDIETTAFEDYYQSGISVVMPVGGQSSNYTDW
EEEEEEECCCCEEEEEECCHHHHCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCCCCC
YNPAKGKDGVWTYKWETFLTTELPQWLGVNKGISPAANAVVGLSMAGPSALTLAIYHPQQ
CCCCCCCCCEEEEEEEEEEEHHCHHHHCCCCCCCCHHHHEEEEEECCCCEEEEEEECCCC
FVYAGALSAPLHPSDQKWQIRVAMSDAGGFNADDMWGPDSDPAWARNDPFLHIDQLIANN
EEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHCC
TRLWIYCGSGDATDLDKDRNGLEVISGGVIEGQVIDSDKKFAEAYGSAGGANAHFEFPKG
CEEEEEECCCCCCCCCCCCCCCEEEECCEEEEEEECCHHHHHHHHCCCCCCCCEEECCCC
GIHNWTYWGNQLRAMKADLVGYLTKPGTAAV
CCCCCEEECCHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]