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The map label for this gene is paaF [H]

Identifier: 169628584

GI number: 169628584

Start: 1506113

End: 1506898

Strand: Reverse

Name: paaF [H]

Synonym: MAB_1493c

Alternate gene names: 169628584

Gene position: 1506898-1506113 (Counterclockwise)

Preceding gene: 169628587

Following gene: 169628579

Centisome position: 29.74

GC content: 65.78

Gene sequence:

>786_bases
ATGTCCGACTACGAAACCCTGCGCATTCGCCGCGATGGATATGTCCTGGTCATCGGTCTGAACCGGCCCGCCAAGCGCAA
TGCCTTCGACAAGACCATGCTCGAAGAACTGGCGCTGGCGCTCGGCGAGTACGAGACCGACACCGACCTGCGTGCCGCGG
TGCTGTACGGCGAGGGCCCGTTGTTCACCGCCGGCCTTGACCTGGCCAGCGTGGCCGCCGAGATTCAAGGCGGCGCATCG
CTGACGCCCGAGGGCGGAATCAACCCGTGGCAGGTCGACGGAAGGCAGCTTTCCAAGCCGCTGCTCGTCGCCGTACACGG
CAAGGTGCTCACACTGGGCATCGAACTGGCACTGGCCGCAGATATCGTGATCGCCGATGAGACCGCGACATTCGCTCAGC
TCGAAGTCAACCGTGGCATCTACCCGTTCGGCGGCGCCACCATTCGCTTCCCCCGCACAGCCGGTTGGGGCAACGCGATG
CGGTGGATGCTGACCGCAGACACCTTCGACGCGGTCGAGGCTCATCGGATCGGCATCGTGCAGGAGATTGTGCCGGTCGG
CGAGCACGTCGACACGGCGATTGCCATCGCCCAGACGATCGCGCGTCAGGCACCGCTGGGCGTGCAGGCGACCCTACGCA
ATGCCAGATTGGCTGTGCGCGAGGGCGATGCGGCTGCCGAGGAGCAGCTGGTGCCCACCGTGCGTGAACTGTTCACCAGT
GAGGACGCCACGCTGGGCGTGCAGGCATTTCTGTCTCGCACCACCGCCGAGTTCGTGGGCCGCTAG

Upstream 100 bases:

>100_bases
AACCATTCGTTCGCGCGGGGTGCTCAATCGTCGTCCTTCCCGAGGAGTTCCGGTCTATGTATGATGCTCTACATAATCCG
CCACCGATCCGGAGAAGTCA

Downstream 100 bases:

>100_bases
CGGGCGCTCACGGCCTTGCGTACGTCACCGAGCTCACCGATCGGCACAGTGCGCGTCGAAGCAACCGGACGCACCCCCGG
GCCGTCCGGCTTGGACACCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSDYETLRIRRDGYVLVIGLNRPAKRNAFDKTMLEELALALGEYETDTDLRAAVLYGEGPLFTAGLDLASVAAEIQGGAS
LTPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIELALAADIVIADETATFAQLEVNRGIYPFGGATIRFPRTAGWGNAM
RWMLTADTFDAVEAHRIGIVQEIVPVGEHVDTAIAIAQTIARQAPLGVQATLRNARLAVREGDAAAEEQLVPTVRELFTS
EDATLGVQAFLSRTTAEFVGR

Sequences:

>Translated_261_residues
MSDYETLRIRRDGYVLVIGLNRPAKRNAFDKTMLEELALALGEYETDTDLRAAVLYGEGPLFTAGLDLASVAAEIQGGAS
LTPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIELALAADIVIADETATFAQLEVNRGIYPFGGATIRFPRTAGWGNAM
RWMLTADTFDAVEAHRIGIVQEIVPVGEHVDTAIAIAQTIARQAPLGVQATLRNARLAVREGDAAAEEQLVPTVRELFTS
EDATLGVQAFLSRTTAEFVGR
>Mature_260_residues
SDYETLRIRRDGYVLVIGLNRPAKRNAFDKTMLEELALALGEYETDTDLRAAVLYGEGPLFTAGLDLASVAAEIQGGASL
TPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIELALAADIVIADETATFAQLEVNRGIYPFGGATIRFPRTAGWGNAMR
WMLTADTFDAVEAHRIGIVQEIVPVGEHVDTAIAIAQTIARQAPLGVQATLRNARLAVREGDAAAEEQLVPTVRELFTSE
DATLGVQAFLSRTTAEFVGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=254, Percent_Identity=31.496062992126, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI70995211, Length=265, Percent_Identity=31.3207547169811, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI25453481, Length=261, Percent_Identity=22.2222222222222, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI51538573, Length=261, Percent_Identity=22.2222222222222, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4502327, Length=280, Percent_Identity=28.2142857142857, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4757966, Length=254, Percent_Identity=22.8346456692913, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI51538581, Length=254, Percent_Identity=22.8346456692913, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4757968, Length=252, Percent_Identity=21.8253968253968, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI49355787, Length=252, Percent_Identity=21.8253968253968, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI221136756, Length=259, Percent_Identity=22.3938223938224, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI221136753, Length=259, Percent_Identity=22.3938223938224, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI260274832, Length=263, Percent_Identity=24.7148288973384, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI45643119, Length=263, Percent_Identity=24.7148288973384, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI260275230, Length=263, Percent_Identity=24.7148288973384, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI221307494, Length=259, Percent_Identity=22.3938223938224, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20127408, Length=182, Percent_Identity=30.2197802197802, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI31542718, Length=184, Percent_Identity=25.5434782608696, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=34.7490347490347, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI221142681, Length=262, Percent_Identity=31.6793893129771, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=31.0077519379845, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082183, Length=272, Percent_Identity=26.8382352941176, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788597, Length=260, Percent_Identity=24.2307692307692, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788682, Length=204, Percent_Identity=27.9411764705882, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=214, Percent_Identity=32.7102803738318, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=210, Percent_Identity=36.6666666666667, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25145438, Length=240, Percent_Identity=32.5, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=269, Percent_Identity=27.1375464684015, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=213, Percent_Identity=30.0469483568075, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=213, Percent_Identity=26.7605633802817, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17558304, Length=223, Percent_Identity=26.9058295964126, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17549921, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25144276, Length=221, Percent_Identity=27.1493212669683, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=263, Percent_Identity=22.4334600760456, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357171, Length=268, Percent_Identity=28.7313432835821, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24650670, Length=215, Percent_Identity=33.4883720930233, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=31.0483870967742, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=31.0483870967742, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24653139, Length=232, Percent_Identity=33.6206896551724, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920382, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24654903, Length=186, Percent_Identity=24.1935483870968, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28041; Mature: 27910

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYETLRIRRDGYVLVIGLNRPAKRNAFDKTMLEELALALGEYETDTDLRAAVLYGEGP
CCCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
LFTAGLDLASVAAEIQGGASLTPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIELALAA
EEEECCHHHHHHHHHCCCCCCCCCCCCCCCEECHHHCCCCEEEEECCEEEEEEEEEEEEE
DIVIADETATFAQLEVNRGIYPFGGATIRFPRTAGWGNAMRWMLTADTFDAVEAHRIGIV
EEEEECCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
QEIVPVGEHVDTAIAIAQTIARQAPLGVQATLRNARLAVREGDAAAEEQLVPTVRELFTS
HHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCC
EDATLGVQAFLSRTTAEFVGR
CCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDYETLRIRRDGYVLVIGLNRPAKRNAFDKTMLEELALALGEYETDTDLRAAVLYGEGP
CCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
LFTAGLDLASVAAEIQGGASLTPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIELALAA
EEEECCHHHHHHHHHCCCCCCCCCCCCCCCEECHHHCCCCEEEEECCEEEEEEEEEEEEE
DIVIADETATFAQLEVNRGIYPFGGATIRFPRTAGWGNAMRWMLTADTFDAVEAHRIGIV
EEEEECCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
QEIVPVGEHVDTAIAIAQTIARQAPLGVQATLRNARLAVREGDAAAEEQLVPTVRELFTS
HHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCC
EDATLGVQAFLSRTTAEFVGR
CCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]