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The map label for this gene is atpD [H]

Identifier: 169628544

GI number: 169628544

Start: 1457404

End: 1458834

Strand: Direct

Name: atpD [H]

Synonym: MAB_1453

Alternate gene names: 169628544

Gene position: 1457404-1458834 (Clockwise)

Preceding gene: 169628543

Following gene: 169628545

Centisome position: 28.76

GC content: 64.57

Gene sequence:

>1431_bases
ATGACCGCACCAACTGCTAACAAGACCGCCGGGCGAGTGGTCCGCGTTACCGGCCCGGTCGTCGACGTGGAGTTCCCGCG
TGACGCCGTGCCGCCGCTCTTCTCCGCCCTCAACGCCGAGATCACCTACGAGGCAATGGCCAAGACGCTGACCCTCGAGG
TGGCACAGCACCTGGGTGACAACCTGGTGCGCACCATCTCGATGCAGCCCACCGACGGCCTGGTCCGTGGCGTGGACGTC
GTCAGCACCGGCAACACCATTGCGGTGCCCGTCGGTGACGGAGTCAAGGGCCACGTGTTCAATGCCCTGGGCAACTGCCT
GGACGAGCCGGGCTACGGCAGCGACTTCGAGAAGTGGTCGATCCACCGCAAGCCGCCGGCCTTCGATCAGCTTGAGCCGC
GTACCGAGATGCTGGAGACCGGTCTGAAGGTCGTCGACCTGCTGACCCCGTACGTGCGTGGTGGCAAGATCGCGCTGTTC
GGTGGTGCTGGTGTGGGCAAGACCGTTCTGATCCAGGAGATGATCAACCGTATCGCCCGCAACTTCGGTGGAACCTCGGT
CTTCGCCGGTGTGGGTGAGCGCACCCGTGAAGGCAACGACCTGTGGGTCGAGCTTGCCGACGCCAACGTGCTCAAGGACA
CCGCCTTGGTGTTCGGCCAGATGGACGAGCCGCCCGGCACGCGTATGAGGGTCGCCCTGTCTGCATTGACGATGGCCGAG
TACTTCCGTGACGAGCAGGGCCAGGACGTGCTGCTGTTCATCGACAACATCTTCCGGTTCACCCAGGCCGGCTCCGAGGT
GTCGACCCTGCTGGGCCGTATGCCTTCGGCCGTGGGTTACCAGCCGACGCTGGCCGATGAGATGGGTGAACTGCAGGAGC
GCATCACCTCGACACGCGGCCGCTCCATCACCTCGATGCAGGCCGTGTACGTGCCCGCCGACGACTACACCGACCCGGCA
CCCGCGACCACATTCGCGCACCTGGACGCCACCACCGAGCTTTCCCGTGCGGTGTTCTCCAAGGGCATCTTCCCGGCTGT
GGATCCGCTGGCGTCGTCGTCGACGATTCTGCTGCCGTCCGTGGTGGGCGAGGAGCACTACCGTGTCGCGCAGGAGGTCA
TCCGCATCCTTCAGCGTTACCAGGACCTGCAGGACATCATCGCCATCCTCGGTATCGACGAGCTGTCGGAAGAGGACAAG
CAGCTGGTGGGCCGCGCGCGTCGTATCGAGCGCTTCCTGAGCCAGAACATGATGGCTGCCGAGCAATTCACCGGTCAGCC
CGGTTCGACCGTGCCGCTCAAGGAAACCATCGAGGCGTTCGACAAGCTCACCAAGGGCGAGTTCGATCATCTGCCCGAGC
AGGCGTTCTTCCTCATCGGTGGCCTGGACGACTTGGCCAAGAAGGCCGAAAGCCTCGGCGCCAAGCTGTAG

Upstream 100 bases:

>100_bases
CTCGCCAGGCCCAGATCACCCAGGAAATCAGCGAAATCGTCGGTGGCGTGAACGCGCTCGCCGACGCTGCAGGCCACTAG
AGAACGAGAAGAGACGAGTA

Downstream 100 bases:

>100_bases
TTCGTCACTAGCCATCTGAAGGAGGTGCATTGAATGTCCGAGATTGATGTCGAGATCGTCGCCGTCGAGCGTGAGATCTG
GTCGGGTAAGGCCACATTCG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MTAPTANKTAGRVVRVTGPVVDVEFPRDAVPPLFSALNAEITYEAMAKTLTLEVAQHLGDNLVRTISMQPTDGLVRGVDV
VSTGNTIAVPVGDGVKGHVFNALGNCLDEPGYGSDFEKWSIHRKPPAFDQLEPRTEMLETGLKVVDLLTPYVRGGKIALF
GGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSALTMAE
YFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPA
PATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILLPSVVGEEHYRVAQEVIRILQRYQDLQDIIAILGIDELSEEDK
QLVGRARRIERFLSQNMMAAEQFTGQPGSTVPLKETIEAFDKLTKGEFDHLPEQAFFLIGGLDDLAKKAESLGAKL

Sequences:

>Translated_476_residues
MTAPTANKTAGRVVRVTGPVVDVEFPRDAVPPLFSALNAEITYEAMAKTLTLEVAQHLGDNLVRTISMQPTDGLVRGVDV
VSTGNTIAVPVGDGVKGHVFNALGNCLDEPGYGSDFEKWSIHRKPPAFDQLEPRTEMLETGLKVVDLLTPYVRGGKIALF
GGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSALTMAE
YFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPA
PATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILLPSVVGEEHYRVAQEVIRILQRYQDLQDIIAILGIDELSEEDK
QLVGRARRIERFLSQNMMAAEQFTGQPGSTVPLKETIEAFDKLTKGEFDHLPEQAFFLIGGLDDLAKKAESLGAKL
>Mature_475_residues
TAPTANKTAGRVVRVTGPVVDVEFPRDAVPPLFSALNAEITYEAMAKTLTLEVAQHLGDNLVRTISMQPTDGLVRGVDVV
STGNTIAVPVGDGVKGHVFNALGNCLDEPGYGSDFEKWSIHRKPPAFDQLEPRTEMLETGLKVVDLLTPYVRGGKIALFG
GAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSALTMAEY
FRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAP
ATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILLPSVVGEEHYRVAQEVIRILQRYQDLQDIIAILGIDELSEEDKQ
LVGRARRIERFLSQNMMAAEQFTGQPGSTVPLKETIEAFDKLTKGEFDHLPEQAFFLIGGLDDLAKKAESLGAKL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=476, Percent_Identity=60.2941176470588, Blast_Score=560, Evalue=1e-160,
Organism=Homo sapiens, GI19913424, Length=322, Percent_Identity=27.9503105590062, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI50345984, Length=437, Percent_Identity=27.2311212814645, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4757810, Length=437, Percent_Identity=27.2311212814645, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI19913426, Length=357, Percent_Identity=23.8095238095238, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI19913428, Length=361, Percent_Identity=23.8227146814404, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1790170, Length=462, Percent_Identity=60.3896103896104, Blast_Score=560, Evalue=1e-161,
Organism=Escherichia coli, GI1788251, Length=303, Percent_Identity=30.6930693069307, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790172, Length=320, Percent_Identity=26.875, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25144756, Length=479, Percent_Identity=59.0814196242171, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI17565854, Length=328, Percent_Identity=28.9634146341463, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=355, Percent_Identity=24.2253521126761, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17570191, Length=353, Percent_Identity=23.5127478753541, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988080, Length=365, Percent_Identity=27.6712328767123, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=365, Percent_Identity=27.6712328767123, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=350, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322581, Length=469, Percent_Identity=59.4882729211087, Blast_Score=547, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6319370, Length=364, Percent_Identity=27.1978021978022, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319603, Length=428, Percent_Identity=24.5327102803738, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=232, Percent_Identity=26.7241379310345, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24638766, Length=468, Percent_Identity=60.4700854700855, Blast_Score=556, Evalue=1e-158,
Organism=Drosophila melanogaster, GI28574560, Length=473, Percent_Identity=58.1395348837209, Blast_Score=530, Evalue=1e-150,
Organism=Drosophila melanogaster, GI20129479, Length=322, Percent_Identity=29.5031055900621, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24583992, Length=347, Percent_Identity=27.0893371757925, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583988, Length=346, Percent_Identity=27.7456647398844, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583986, Length=346, Percent_Identity=27.7456647398844, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583984, Length=346, Percent_Identity=27.7456647398844, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281361666, Length=360, Percent_Identity=25.2777777777778, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646341, Length=360, Percent_Identity=25.2777777777778, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17136796, Length=360, Percent_Identity=25.2777777777778, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24658560, Length=364, Percent_Identity=26.3736263736264, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24638768, Length=94, Percent_Identity=47.8723404255319, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 51751; Mature: 51619

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPTANKTAGRVVRVTGPVVDVEFPRDAVPPLFSALNAEITYEAMAKTLTLEVAQHLGD
CCCCCCCCCCCCEEEEECCEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
NLVRTISMQPTDGLVRGVDVVSTGNTIAVPVGDGVKGHVFNALGNCLDEPGYGSDFEKWS
HHEEEEECCCCCCHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHCC
IHRKPPAFDQLEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIAR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
NFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSALTMAE
HCCCCHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
YFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRG
HHHCCCCCEEEEHHHHHHHHHHCCHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHCC
RSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILLPS
CCEEEEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHH
VVGEEHYRVAQEVIRILQRYQDLQDIIAILGIDELSEEDKQLVGRARRIERFLSQNMMAA
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFTGQPGSTVPLKETIEAFDKLTKGEFDHLPEQAFFLIGGLDDLAKKAESLGAKL
HHHCCCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHEEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAPTANKTAGRVVRVTGPVVDVEFPRDAVPPLFSALNAEITYEAMAKTLTLEVAQHLGD
CCCCCCCCCCCEEEEECCEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
NLVRTISMQPTDGLVRGVDVVSTGNTIAVPVGDGVKGHVFNALGNCLDEPGYGSDFEKWS
HHEEEEECCCCCCHHHCCEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHCC
IHRKPPAFDQLEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIAR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHH
NFGGTSVFAGVGERTREGNDLWVELADANVLKDTALVFGQMDEPPGTRMRVALSALTMAE
HCCCCHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
YFRDEQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRG
HHHCCCCCEEEEHHHHHHHHHHCCHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHCC
RSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRAVFSKGIFPAVDPLASSSTILLPS
CCEEEEEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHH
VVGEEHYRVAQEVIRILQRYQDLQDIIAILGIDELSEEDKQLVGRARRIERFLSQNMMAA
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFTGQPGSTVPLKETIEAFDKLTKGEFDHLPEQAFFLIGGLDDLAKKAESLGAKL
HHHCCCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHEEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA