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The map label for this gene is atpA

Identifier: 169628542

GI number: 169628542

Start: 1454801

End: 1456447

Strand: Direct

Name: atpA

Synonym: MAB_1451

Alternate gene names: 169628542

Gene position: 1454801-1456447 (Clockwise)

Preceding gene: 169628541

Following gene: 169628543

Centisome position: 28.71

GC content: 65.7

Gene sequence:

>1647_bases
ATGACAGAGTTGACGATCTCCTCGGCGGATATCTCCGGCGCGATCGAGCAGTACGTCGCGACGTTCTCTGCCGACCCCAC
CCGCGAAGAAATCGGCATCGTCTCCGACGCCGGTGACGGCATCGCCCACGTCGAGGGTCTGCCCTCCGTGATGACCCAGG
AACTCCTCGAGTTCCCCGGTGGCGTGCTGGGCGTGGCGCTGAACCTCGACGAGCGCAGCGTCGGCACCGTTGTCCTCGGT
GACTTCCAGGACATCGAAGAAGGCCAGCAGGTCAAGCGCACCGGTGAAGTGCTCTCGGTACCCGTCGGCGACGCCTTCCT
CGGCCGCGTCATCAACCCACTGGGCCAGCCGATCGACGGCCGCGGCGACATCGAAGCCGAGACCCGTCGTGCCCTCGAGC
TCCAGGCCCCGAGCGTGGTCCAGCGTCAAAGTGTTTCGGAGCCGCTGCAGACCGGCATCAAGGCGATCGATTCGCAGACT
CCGATCGGCCGCGGTCAGCGTCAGCTGATCATCGGCGACCGCAAGACCGGCAAGACCGCGGTCTGCATCGACACCATCCT
GAACCAGAAGCAGGCCTGGGAGACCGGTGATCCGGCTCAGCAGGTGCGCTGCATCTACGTTGCCGTCGGCCAGAAGGGTT
CCACCGTCGCCGCCGTGCGACGCACCCTGGACGAGGCCGGCGCTCTGGAATACACCACCATCGTCGCCGCCCCGGCCTCC
GACGCCGCCGGCTTCAAGTGGCTGGCCCCGTACACCGGCTCCGCCCTCGGTCAGCACTGGATGTACCAGGGCAAGCACGT
TCTGATCGTGTTCGACGACCTGACCAAGCAGGCCGAGGCCTACCGCGCCATCTCGCTGCTGCTGCGTCGTCCGCCGGGCC
GCGAGGCGTACCCCGGTGACGTCTTCTACCTGCACTCGCGTCTGCTGGAGCGTTGCGCGAAGCTTTCCGATGAGCTGGGT
GCCGGCTCGCTGACCGGTCTGCCGATCATCGAGACCAAGGCCAACGATATTTCGGCCTACATTCCGACCAACGTCATCTC
CATCACCGACGGCCAGTGCTTCCTGCAGACCGACCTGTTCAACCAGGGTGTGCGCCCCGCCGTCAACGTCGGTGTGTCGG
TCTCCCGCGTCGGTGGTGCCGCGCAGATCAAGGCGATGAAGGAGGTGGCAGGCTCGCTGCGTCTGGAGCTGTCGCAGTAC
CGCGAGCTGGAAGCCTTCGCGGCCTTCGCCTCCGACCTGGATGCCACCTCGAAGGCTCAGCTCGAGCGTGGTGCTCGTCT
GGTCGAGCTGCTCAAGCAGCCGCAGAACTCCCCGTACCCGGTTGAGGAGCAGGTCGTCGCCATCTACCTGGGCACCGGTG
GTCATCTCGACTCGGTGCCGGTTGAGGACGTCATGCGTTTTGAGCAGGAGTTCCTCGACCACGTGCGCGGTTCGCACGCC
GACATCCTCGCCGACATCCGGGAGACCAAGAAGTTCTCCGAGGACACCGAGACCAAGCTGACCAACGCCGTGAACGCCTT
CAAGAAGAGTTTTGCGGCGACCGATGGCAGCTCGGTTGAGGTCAAGGGTGTCGCCGCCGAGGCGCTCGACGAGTCCGCGG
TCGGGCAGGAAACCGTCCAGGTCCGCAAGCCGGCTCCCAAGAAGTAG

Upstream 100 bases:

>100_bases
GACGGCAGCCTGTCCACCCGGCTTTCCGCGGCCGCCCTACATCTGCCCAACTAACCACCATTAGACCTACCCCGATAGAC
GAGCAGGAAGACGAAAAGCC

Downstream 100 bases:

>100_bases
CAACGAGCCATGGGTGCACAAATCCGAGAACTGCGCCGGCGGATCAAATCCGCCGGAGCGATCAAAAAGATCACCAAGGC
GCAGGAACTGATCGCGACAT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MTELTISSADISGAIEQYVATFSADPTREEIGIVSDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDERSVGTVVLG
DFQDIEEGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDGRGDIEAETRRALELQAPSVVQRQSVSEPLQTGIKAIDSQT
PIGRGQRQLIIGDRKTGKTAVCIDTILNQKQAWETGDPAQQVRCIYVAVGQKGSTVAAVRRTLDEAGALEYTTIVAAPAS
DAAGFKWLAPYTGSALGQHWMYQGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELG
AGSLTGLPIIETKANDISAYIPTNVISITDGQCFLQTDLFNQGVRPAVNVGVSVSRVGGAAQIKAMKEVAGSLRLELSQY
RELEAFAAFASDLDATSKAQLERGARLVELLKQPQNSPYPVEEQVVAIYLGTGGHLDSVPVEDVMRFEQEFLDHVRGSHA
DILADIRETKKFSEDTETKLTNAVNAFKKSFAATDGSSVEVKGVAAEALDESAVGQETVQVRKPAPKK

Sequences:

>Translated_548_residues
MTELTISSADISGAIEQYVATFSADPTREEIGIVSDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDERSVGTVVLG
DFQDIEEGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDGRGDIEAETRRALELQAPSVVQRQSVSEPLQTGIKAIDSQT
PIGRGQRQLIIGDRKTGKTAVCIDTILNQKQAWETGDPAQQVRCIYVAVGQKGSTVAAVRRTLDEAGALEYTTIVAAPAS
DAAGFKWLAPYTGSALGQHWMYQGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELG
AGSLTGLPIIETKANDISAYIPTNVISITDGQCFLQTDLFNQGVRPAVNVGVSVSRVGGAAQIKAMKEVAGSLRLELSQY
RELEAFAAFASDLDATSKAQLERGARLVELLKQPQNSPYPVEEQVVAIYLGTGGHLDSVPVEDVMRFEQEFLDHVRGSHA
DILADIRETKKFSEDTETKLTNAVNAFKKSFAATDGSSVEVKGVAAEALDESAVGQETVQVRKPAPKK
>Mature_547_residues
TELTISSADISGAIEQYVATFSADPTREEIGIVSDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDERSVGTVVLGD
FQDIEEGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDGRGDIEAETRRALELQAPSVVQRQSVSEPLQTGIKAIDSQTP
IGRGQRQLIIGDRKTGKTAVCIDTILNQKQAWETGDPAQQVRCIYVAVGQKGSTVAAVRRTLDEAGALEYTTIVAAPASD
AAGFKWLAPYTGSALGQHWMYQGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELGA
GSLTGLPIIETKANDISAYIPTNVISITDGQCFLQTDLFNQGVRPAVNVGVSVSRVGGAAQIKAMKEVAGSLRLELSQYR
ELEAFAAFASDLDATSKAQLERGARLVELLKQPQNSPYPVEEQVVAIYLGTGGHLDSVPVEDVMRFEQEFLDHVRGSHAD
ILADIRETKKFSEDTETKLTNAVNAFKKSFAATDGSSVEVKGVAAEALDESAVGQETVQVRKPAPKK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=506, Percent_Identity=55.7312252964427, Blast_Score=578, Evalue=1e-165,
Organism=Homo sapiens, GI4757810, Length=506, Percent_Identity=55.7312252964427, Blast_Score=578, Evalue=1e-165,
Organism=Homo sapiens, GI19913428, Length=293, Percent_Identity=28.6689419795222, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI32189394, Length=449, Percent_Identity=24.9443207126949, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913426, Length=293, Percent_Identity=27.9863481228669, Blast_Score=109, Evalue=6e-24,
Organism=Escherichia coli, GI1790172, Length=518, Percent_Identity=49.4208494208494, Blast_Score=518, Evalue=1e-148,
Organism=Escherichia coli, GI1790170, Length=364, Percent_Identity=25.2747252747253, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788251, Length=323, Percent_Identity=26.3157894736842, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=505, Percent_Identity=57.2277227722772, Blast_Score=591, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI71988080, Length=505, Percent_Identity=57.2277227722772, Blast_Score=589, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI71988074, Length=505, Percent_Identity=53.6633663366337, Blast_Score=538, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17570191, Length=291, Percent_Identity=28.8659793814433, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=355, Percent_Identity=25.6338028169014, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=453, Percent_Identity=23.3995584988962, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=55.0695825049702, Blast_Score=565, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6322581, Length=399, Percent_Identity=26.8170426065163, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319603, Length=296, Percent_Identity=28.7162162162162, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24658560, Length=507, Percent_Identity=55.818540433925, Blast_Score=577, Evalue=1e-165,
Organism=Drosophila melanogaster, GI281361666, Length=302, Percent_Identity=29.1390728476821, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=302, Percent_Identity=29.1390728476821, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=302, Percent_Identity=29.1390728476821, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24638766, Length=418, Percent_Identity=26.0765550239234, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28574560, Length=431, Percent_Identity=24.5939675174014, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_MYCA9 (B1MLW0)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702191.1
- ProteinModelPortal:   B1MLW0
- SMR:   B1MLW0
- EnsemblBacteria:   EBMYCT00000004777
- GeneID:   5963972
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_1451
- GeneTree:   EBGT00050000014996
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   MABS561007:MAB_1451-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 58855; Mature: 58724

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELTISSADISGAIEQYVATFSADPTREEIGIVSDAGDGIAHVEGLPSVMTQELLEFPG
CCEEEECCCHHHHHHHHHHHHHCCCCCHHHCCEEECCCCCHHHHCCCHHHHHHHHHHCCC
GVLGVALNLDERSVGTVVLGDFQDIEEGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDG
CEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCC
RGDIEAETRRALELQAPSVVQRQSVSEPLQTGIKAIDSQTPIGRGQRQLIIGDRKTGKTA
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEE
VCIDTILNQKQAWETGDPAQQVRCIYVAVGQKGSTVAAVRRTLDEAGALEYTTIVAAPAS
EHHHHHHCHHHCCCCCCHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEECCC
DAAGFKWLAPYTGSALGQHWMYQGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGD
CCCCCEEECCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCH
VFYLHSRLLERCAKLSDELGAGSLTGLPIIETKANDISAYIPTNVISITDGQCFLQTDLF
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCCEEEEEHHH
NQGVRPAVNVGVSVSRVGGAAQIKAMKEVAGSLRLELSQYRELEAFAAFASDLDATSKAQ
CCCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LERGARLVELLKQPQNSPYPVEEQVVAIYLGTGGHLDSVPVEDVMRFEQEFLDHVRGSHA
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHH
DILADIRETKKFSEDTETKLTNAVNAFKKSFAATDGSSVEVKGVAAEALDESAVGQETVQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCHHHHH
VRKPAPKK
CCCCCCCC
>Mature Secondary Structure 
TELTISSADISGAIEQYVATFSADPTREEIGIVSDAGDGIAHVEGLPSVMTQELLEFPG
CEEEECCCHHHHHHHHHHHHHCCCCCHHHCCEEECCCCCHHHHCCCHHHHHHHHHHCCC
GVLGVALNLDERSVGTVVLGDFQDIEEGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDG
CEEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCC
RGDIEAETRRALELQAPSVVQRQSVSEPLQTGIKAIDSQTPIGRGQRQLIIGDRKTGKTA
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEE
VCIDTILNQKQAWETGDPAQQVRCIYVAVGQKGSTVAAVRRTLDEAGALEYTTIVAAPAS
EHHHHHHCHHHCCCCCCHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEECCC
DAAGFKWLAPYTGSALGQHWMYQGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGD
CCCCCEEECCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCH
VFYLHSRLLERCAKLSDELGAGSLTGLPIIETKANDISAYIPTNVISITDGQCFLQTDLF
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCCEEEEEHHH
NQGVRPAVNVGVSVSRVGGAAQIKAMKEVAGSLRLELSQYRELEAFAAFASDLDATSKAQ
CCCCCCHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LERGARLVELLKQPQNSPYPVEEQVVAIYLGTGGHLDSVPVEDVMRFEQEFLDHVRGSHA
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHH
DILADIRETKKFSEDTETKLTNAVNAFKKSFAATDGSSVEVKGVAAEALDESAVGQETVQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCHHHHH
VRKPAPKK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA