Click here to switch to the map view.

The map label for this gene is atpFH

Identifier: 169628541

GI number: 169628541

Start: 1453408

End: 1454754

Strand: Direct

Name: atpFH

Synonym: MAB_1450

Alternate gene names: 169628541

Gene position: 1453408-1454754 (Clockwise)

Preceding gene: 169628540

Following gene: 169628542

Centisome position: 28.68

GC content: 66.67

Gene sequence:

>1347_bases
ATGTCGACATTTATCGGACAGCTCATCGGTTTCGCTGTCATTGTGTTCCTGGTGGTCAAGTACGTGGTGCCGCCGGTGCG
CACGTTGATGGCCAAGCAGCAGGATGCGGTACGCCAGCAGCTCGCTGACAGCAAGACCGCTGCGGACAAGCTGGTCGAGG
CCGAAGGCGCGCACGCCAAGGCCATCGAAGACGCCAAGGCCGATGCCGCCCAGATCGCGGAAGAAGCCAAGGCCGATGCG
GTCCAGATCTCGAAGCAGCTGCGTGAGCAGGCCGATGCCGAGGTCGAGCGGATCAAGGTGCACGGCCAGGAGCAGATCGT
GCTCCAGCGCCAACAACTGATCCGTCAGCTCCGCGGCGACCTCGGAGCCGAATCCGTGCGCCGCGCAGGCGACCTGGTGC
GCTCGCATGTGGCCGACCCGTCGGCTCAATCGGCCACGGTCGACCGTTTCCTCGACGAGCTGTCGCAGATGGCCGGCAGC
GTCGGTGCCGCCAAACGCCCGGTACCCGGTGGCTACTCCGGTATGCACGCGGCCAGCCGCGAATCCCTGGCTGCCCAGGT
GAGCACGTTCCGCGAGACCGCGGCTTCGCTGGATTCGTCGGCGCTCAGTGCGCTCGCCGAGGACATCGCCGCCGTCGCCG
AGCTGCTGATCTCCGAGCTCGTGCTGCGCAAGCATCTTTCCGAGCCGGTGGACGCCAGCGAGAACGAGGCCAAGCTGACG
CTCGTGAATTCGTTGCTCGGCAACAAGATCGGCGCCCCGGCACTCGCCATCGTGCGTTCGGCCGTCACCGCGCGGTGGTC
GGCCTCCAGCGACCTGATCACCTCGCTGGAGTACATCGCGCGGCTGGCACTGCTGGAGCGCGCTGAACGGGACGGCCAGA
TCGAGGATGTCGAAGACCAGTTGTTCCGGGTGAGCCGAGTGCTCGACGCGGAGCCGCAGCTGGCCACCCTGCTCAGCGAT
TCGACTGCTCCGGCGCAGGGGCGAGTTGCCCTGCTGACCAACGTGTTGGGCGGACGTGCCAACGAGGTGACCACCGCATT
GCTCGCGCAGACGGTACGGCTGCTGTATTCGGTTCGCGCCGAGGTTGCGGTATTGGACGTCGCCGAGCTGGCGGTCGCCC
GCCGCGATGAGTCGGTGGCTCACGTGAAGGCAGCCGCACCCATCACTGACGCACAGCGCACCCGGCTGGCCCAGGTGCTC
GGACAGATTTACGGCCGCACCATCGCGGTGCAGTTGGATGTGGACCCCGAACTGCTGGGCGGGCTCGTCGTCAACATCGG
TGACGAGGAGATCGACGGCAGCCTGTCCACCCGGCTTTCCGCGGCCGCCCTACATCTGCCCAACTAA

Upstream 100 bases:

>100_bases
GCTGGCGACGAACGTCGACAGCTTGTCCCGGACCCTCGCCGAACGCGTTCTCGGCGTGAGCCTTTCGGAACCAGCGAACG
CAGGGCGAGGCTAAACACAG

Downstream 100 bases:

>100_bases
CCACCATTAGACCTACCCCGATAGACGAGCAGGAAGACGAAAAGCCATGACAGAGTTGACGATCTCCTCGGCGGATATCT
CCGGCGCGATCGAGCAGTAC

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase subunit b; ATP synthase F(0) sector subunit b 2; ATPase subunit I 2; F-type ATPase subunit b 2; F-ATPase subunit b 2; ATP synthase subunit delta; ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MSTFIGQLIGFAVIVFLVVKYVVPPVRTLMAKQQDAVRQQLADSKTAADKLVEAEGAHAKAIEDAKADAAQIAEEAKADA
VQISKQLREQADAEVERIKVHGQEQIVLQRQQLIRQLRGDLGAESVRRAGDLVRSHVADPSAQSATVDRFLDELSQMAGS
VGAAKRPVPGGYSGMHAASRESLAAQVSTFRETAASLDSSALSALAEDIAAVAELLISELVLRKHLSEPVDASENEAKLT
LVNSLLGNKIGAPALAIVRSAVTARWSASSDLITSLEYIARLALLERAERDGQIEDVEDQLFRVSRVLDAEPQLATLLSD
STAPAQGRVALLTNVLGGRANEVTTALLAQTVRLLYSVRAEVAVLDVAELAVARRDESVAHVKAAAPITDAQRTRLAQVL
GQIYGRTIAVQLDVDPELLGGLVVNIGDEEIDGSLSTRLSAAALHLPN

Sequences:

>Translated_448_residues
MSTFIGQLIGFAVIVFLVVKYVVPPVRTLMAKQQDAVRQQLADSKTAADKLVEAEGAHAKAIEDAKADAAQIAEEAKADA
VQISKQLREQADAEVERIKVHGQEQIVLQRQQLIRQLRGDLGAESVRRAGDLVRSHVADPSAQSATVDRFLDELSQMAGS
VGAAKRPVPGGYSGMHAASRESLAAQVSTFRETAASLDSSALSALAEDIAAVAELLISELVLRKHLSEPVDASENEAKLT
LVNSLLGNKIGAPALAIVRSAVTARWSASSDLITSLEYIARLALLERAERDGQIEDVEDQLFRVSRVLDAEPQLATLLSD
STAPAQGRVALLTNVLGGRANEVTTALLAQTVRLLYSVRAEVAVLDVAELAVARRDESVAHVKAAAPITDAQRTRLAQVL
GQIYGRTIAVQLDVDPELLGGLVVNIGDEEIDGSLSTRLSAAALHLPN
>Mature_447_residues
STFIGQLIGFAVIVFLVVKYVVPPVRTLMAKQQDAVRQQLADSKTAADKLVEAEGAHAKAIEDAKADAAQIAEEAKADAV
QISKQLREQADAEVERIKVHGQEQIVLQRQQLIRQLRGDLGAESVRRAGDLVRSHVADPSAQSATVDRFLDELSQMAGSV
GAAKRPVPGGYSGMHAASRESLAAQVSTFRETAASLDSSALSALAEDIAAVAELLISELVLRKHLSEPVDASENEAKLTL
VNSLLGNKIGAPALAIVRSAVTARWSASSDLITSLEYIARLALLERAERDGQIEDVEDQLFRVSRVLDAEPQLATLLSDS
TAPAQGRVALLTNVLGGRANEVTTALLAQTVRLLYSVRAEVAVLDVAELAVARRDESVAHVKAAAPITDAQRTRLAQVLG
QIYGRTIAVQLDVDPELLGGLVVNIGDEEIDGSLSTRLSAAALHLPN

Specific function: This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral "stator" stalk which links F(1) to F(0)

COG id: COG0711

COG function: function code C; F0F1-type ATP synthase, subunit b

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATPase delta chain family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPFD_MYCA9 (B1MLV9)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702190.1
- ProteinModelPortal:   B1MLV9
- SMR:   B1MLV9
- EnsemblBacteria:   EBMYCT00000004530
- GeneID:   5963971
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_1450
- GeneTree:   EBGT00050000016867
- HOGENOM:   HBG566588
- OMA:   YVVPPVR
- ProtClustDB:   PRK13428
- BioCyc:   MABS561007:MAB_1450-MONOMER
- HAMAP:   MF_01398
- HAMAP:   MF_01416
- InterPro:   IPR002146
- InterPro:   IPR005864
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01144
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00430 ATP-synt_B; PF00213 OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 47644; Mature: 47512

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00389 ATPASE_DELTA; PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1fdb7504)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFIGQLIGFAVIVFLVVKYVVPPVRTLMAKQQDAVRQQLADSKTAADKLVEAEGAHAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AIEDAKADAAQIAEEAKADAVQISKQLREQADAEVERIKVHGQEQIVLQRQQLIRQLRGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
LGAESVRRAGDLVRSHVADPSAQSATVDRFLDELSQMAGSVGAAKRPVPGGYSGMHAASR
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
ESLAAQVSTFRETAASLDSSALSALAEDIAAVAELLISELVLRKHLSEPVDASENEAKLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LVNSLLGNKIGAPALAIVRSAVTARWSASSDLITSLEYIARLALLERAERDGQIEDVEDQ
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LFRVSRVLDAEPQLATLLSDSTAPAQGRVALLTNVLGGRANEVTTALLAQTVRLLYSVRA
HHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EVAVLDVAELAVARRDESVAHVKAAAPITDAQRTRLAQVLGQIYGRTIAVQLDVDPELLG
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHC
GLVVNIGDEEIDGSLSTRLSAAALHLPN
CEEEECCCHHHCCHHHHHHHHHHHCCCH
>Mature Secondary Structure 
STFIGQLIGFAVIVFLVVKYVVPPVRTLMAKQQDAVRQQLADSKTAADKLVEAEGAHAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AIEDAKADAAQIAEEAKADAVQISKQLREQADAEVERIKVHGQEQIVLQRQQLIRQLRGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
LGAESVRRAGDLVRSHVADPSAQSATVDRFLDELSQMAGSVGAAKRPVPGGYSGMHAASR
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH
ESLAAQVSTFRETAASLDSSALSALAEDIAAVAELLISELVLRKHLSEPVDASENEAKLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LVNSLLGNKIGAPALAIVRSAVTARWSASSDLITSLEYIARLALLERAERDGQIEDVEDQ
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LFRVSRVLDAEPQLATLLSDSTAPAQGRVALLTNVLGGRANEVTTALLAQTVRLLYSVRA
HHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EVAVLDVAELAVARRDESVAHVKAAAPITDAQRTRLAQVLGQIYGRTIAVQLDVDPELLG
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHC
GLVVNIGDEEIDGSLSTRLSAAALHLPN
CEEEECCCHHHCCHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA